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Oligonucleotides for Long QT Syndrome
Oligonucleotides to prevent poly(A) adenylation at intron 9 of the KCNH2 gene, and pharmaceutical compositions comprising the oligonucleotides and methods to use same to treat long QT syndrome. Included are antisense sequences to specific sites in intron 9. KCNH2, also known as ether-a-go-go related gene 1 (hERG1) encodes the Kv11.1 channel that conducts...
Published: 1/29/2015   |   Inventor(s): Zhengfeng Zhou, Qiuming Gong, Matthew Stump
Keywords(s): Therapeutics, Therapeutics - General, Therapeutics - Other
Category(s): Therapeutics
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