<?xml version="1.0" encoding="utf-8"?><rss version="2.0"><channel><title>Latest technologies from Oregon Portal</title><link>http://icoregon.technologypublisher.com</link><description>Be the first to know about the latest inventions and technologies available from Oregon Portal 2</description><language>en-US</language><pubDate>Mon, 13 Apr 2026 15:12:57 GMT</pubDate><lastBuildDate>Fri, 03 Apr 2026 16:02:06 GMT</lastBuildDate><docs>http://blogs.law.harvard.edu/tech/rss</docs><webMaster>borenk@ohsu.edu</webMaster><copyright>Copyright 2026, Oregon Portal</copyright><item><title>Next-Generation Photothermal Nanoagent for Safe Systemic Tumor Ablation</title><caseId>OSU-25-56</caseId><link>http://icoregon.technologypublisher.com/technology/61069</link><description><![CDATA[A resonance energy transfer (RET)&ndash;engineered nanoplatform enabling complete tumor ablation using near-infrared irradiation 

Background   
Photothermal therapy (PTT) uses NIR light to generate localized tumor heating. However, many systems require elevated laser power densities to achieve therapeutic temperatures, limiting translational feasibility. A systemically deliverable photothermal agent capable of operating within low-power irradiation parameters is needed to advance oncology applications. 

Technology Description    
This technology enables systemic, image-guided photothermal tu...]]></description><pubDate>Fri, 03 Apr 2026 16:02:06 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/61069</guid></item><item><title>3D Multilayer Multicellular In Vitro Model of Endometrial Cancer</title><caseId>OSU-24-11</caseId><link>http://icoregon.technologypublisher.com/technology/60977</link><description>A 3D in vitro model of endometrial cancer incorporating endothelial and endometrial cancer cells to facilitate drug screening analysis. 

Background 
As the number of patients diagnosed with endometrial cancer keeps increasing, the demand for physiologically relevant and high-throughput screening platforms also increases. In recent years, 3D in vitro models have gained attention for their use in screening novel anticancer drugs. However, there are limited 3D in vitro models tested with chemotherapy agents specifically targeting endometrial cancer. Many current treatments have faltered due to t...</description><pubDate>Mon, 23 Mar 2026 16:56:09 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60977</guid></item><item><title>Hybrid Water and Nutrient Recovery Process</title><caseId>OSU-23-35</caseId><link>http://icoregon.technologypublisher.com/technology/60976</link><description>
This process is a combination of electrodialysis (ED) and forward osmosis (FO) to recover nutrients and water from wastewater streams. 

Background 
The agriculture sector is the largest freshwater consumer in the United States, accounting for up to 70% of available freshwater withdrawals. However, water shortage has been exacerbated and is becoming a critical problem in many regions of the country where more frequent and intense droughts are expected. Given that water shortages in agriculture can have far-reaching effects on food security, more and more regions see irrigation with reclaimed ...</description><pubDate>Mon, 23 Mar 2026 15:12:04 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60976</guid></item><item><title>Novel Reactor Design for Particle-gas Counterflow</title><caseId>OSU-23-26</caseId><link>http://icoregon.technologypublisher.com/technology/60975</link><description>
This reactor design incorporates a fluidized bed, a counterflow gravity-driven spouted bed, transitioning to a moving bed. 

Background 
Thermochemical energy storage (TCES) using metal oxide particles has emerged as a promising technology to enable renewable energy dispatchability. The basic principle of TCES is to store energy as chemical bonds in metal oxide particles for short or long-term periods, which can then be released as heat when needed. In addition to providing energy storage, TCES offers several other advantages, including high energy density, decoupled charging and discharging ...</description><pubDate>Mon, 23 Mar 2026 14:33:43 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60975</guid></item><item><title>Tensioning Tool for Flexible Materials</title><caseId>OSU-22-03</caseId><link>http://icoregon.technologypublisher.com/technology/60974</link><description>
Tensioning Tool for Flexible Materials

Background
This tool can securely hold flexible materials, like tendons or ligaments, under accurate tension while affixing the material.

Technology Description
Engineers or surgeons often need to mount a flexible length of material on a surface. Flexible lengths of material can include wires, cables, ropes, or soft connective tissues such as tendons and ligaments. After applying a specific amount of tension to a flexible material it can often be difficult to hold the material at that tension while simultaneously mounting it on a surface. In many setti...</description><pubDate>Mon, 23 Mar 2026 14:01:55 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60974</guid></item><item><title>Furanic Quaternary Ammonium Salt Antibacterial Compounds</title><caseId>OSU-21-10</caseId><link>http://icoregon.technologypublisher.com/technology/60945</link><description>This technology describes novel quaternary ammonium salt compounds with antibacterial properties and their methods of making.

Background   
Increased resistance to current antibiotics and QAS compounds exhibited by bacteria requires the discovery and production of new formulations. Moreover, the replacement of the benzyl functionality of traditional QAS bactericidals with a furyl group promises significant improvements in the sustainability of their production and use, as well as improved supply chain logistics, given that furfural is a broadly available raw material sourced from biomass. 

T...</description><pubDate>Wed, 18 Mar 2026 14:57:46 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60945</guid></item><item><title>Nanomaterial Printhead for Additive Manufacturing</title><caseId>OSU-19-90</caseId><link>http://icoregon.technologypublisher.com/technology/60941</link><description>This printhead can deposit reactive materials as they are generated in real time 

Background 
The ability to integrate multifunctional parameters into one material has crosscutting impacts in several applications. For example, one can engineer and modify structural materials that provide high mechanical strength at various length scales to attain additional functionality, such as sensing, actuation, and energy transport. Such materials are critical in smart systems in which material properties such as chemical, mechanical, optical, and electrical characteristics respond to external stimuli. T...</description><pubDate>Wed, 18 Mar 2026 11:55:40 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60941</guid></item><item><title>Membrane-less, Gravity Independent Liquid-Liquid and Gas-Liquid Extraction and Phase Separation</title><caseId>OSU-22-46</caseId><link>http://icoregon.technologypublisher.com/technology/60940</link><description>A membrane-less device enabling liquid-liquid and gas-liquid separation without requiring gravity 

Background   
The separation of mixtures of fluid phases, particularly liquid-liquid and gas-liquid extraction, is relevant to many industrial chemical and biochemical processes, including fuels production, pharmaceuticals, and hydrometallurgy. Many solvent extraction processes, however, are reliant on costly and bulky equipment which requires considerable investment. Furthermore, this equipment may rely on gravitational forces, membranes, or other components that impose restrictions on the use ...</description><pubDate>Wed, 18 Mar 2026 10:07:15 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60940</guid></item><item><title>Inclusion Body–Based Expression Platform for PTM-Preserved Proteins (PIInBody)</title><caseId>OSU-25-67</caseId><link>http://icoregon.technologypublisher.com/technology/60508</link><description>Enables high-yield production of unstable, post-translationally modified proteins by protecting them during expression and gentle release 

Background   
Intrinsically disordered proteins (IDPs), particularly those carrying labile post-translational modifications (PTMs), are difficult to produce recombinantly due to degradation, aggregation, and loss of modification during expression. Existing strategies often yield low quantities, heterogeneous products, or require harsh chemical treatments that damage sensitive PTMs, limiting their use in research, diagnostics, and drug discovery. 

Technolo...</description><pubDate>Thu, 19 Feb 2026 11:09:10 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/60508</guid></item><item><title>Seafarer Lantern</title><caseId>UO-22-053</caseId><link>http://icoregon.technologypublisher.com/technology/59778</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a versatile lantern designed for sailors and boaters, combining the functionality of a camping lantern, navigation lights, and an anchor light into&nbsp;a compact, sturdy housing. The lantern features color-changing LEDs, an adjustable hanging cable made of strong&nbsp;Dyneema&nbsp;line, and&nbsp;is rechargeable through a waterproof USB port. This innovative design offers significant potential for applications in outdoor equipment, marine accessories, and emergency lighting.&nbsp;The technology&nbsp;is currently in the development stage an...]]></description><pubDate>Sun, 04 Jan 2026 13:20:59 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59778</guid></item><item><title>3D Printed Electrodes</title><caseId>UO-21-008</caseId><link>http://icoregon.technologypublisher.com/technology/59769</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel method for fabricating 3D electronic devices using 3D-printed electronic components. This technology leverages 3D printing techniques to create complex multi-electrode arrays for brain recording and stimulation, integrating neurotrophic factors to enhance functionality. The technology offers significant potential for applications in medical devices, wearable electronics, and robotics, providing a scalable and cost-effective solution for advanced electronic&nbsp;component&nbsp;fabrication. Currently in the development stage, this te...]]></description><pubDate>Fri, 02 Jan 2026 18:10:23 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59769</guid></item><item><title>Advanced Catalysts for Water Oxidation Alkaline and Alkaline Membrane Electrolyzers</title><caseId>UO-24-012</caseId><link>http://icoregon.technologypublisher.com/technology/59768</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel catalytic architecture for water oxidation electrodes, specifically designed for alkaline membrane&nbsp;electrolyzers. This advanced catalyst&nbsp;leverages&nbsp;a multicomponent metal oxide structure to achieve superior performance, high electrical conductivity, and stability under water oxidation conditions. The technology is currently in the development stage and holds significant potential for cross-industry applications in hydrogen production, fuel cells, and renewable energy. The invention is protected by pending patents, ens...]]></description><pubDate>Fri, 02 Jan 2026 18:07:16 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59768</guid></item><item><title>Passivated Anode for Membrane Water Electrolyzers</title><caseId>UO-22-021</caseId><link>http://icoregon.technologypublisher.com/technology/59767</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a passivated anode for membrane water&nbsp;electrolyzers, designed to increase durability and performance by preventing unwanted oxidation of ionomers. The anode is coated with a thin layer of a porous ion-permeable oxide, such as HfO2, allowing the flow of hydroxide ions to the catalyst while preventing electron flow from ionomer to catalyst. This innovative design offers significant potential for applications in hydrogen production, fuel cells, and electrochemical processes. Currently in the development stage, this technology holds stron...]]></description><pubDate>Fri, 02 Jan 2026 18:00:21 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59767</guid></item><item><title>Donor/Acceptor Nanohoops</title><caseId>UO-15-24</caseId><link>http://icoregon.technologypublisher.com/technology/59766</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on donor/acceptor&nbsp;nanohoops, which are novel, conjugated, hoop-shaped molecules designed for organic semiconducting materials. These&nbsp;nanohoops&nbsp;incorporate electron-donating and electron-accepting molecules into their structure, allowing for easy tuning of band gaps. The technology is currently in the development stage, with promising cross-industry applications in organic electronics, sensing technologies, and material science.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Enhanced Solubility: Provides better solubility compar...]]></description><pubDate>Fri, 02 Jan 2026 15:35:29 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59766</guid></item><item><title>Electrochemical Cell Designs for Producing Iron Metal from Oxide Powders and Salt Water</title><caseId>UO-24-026</caseId><link>http://icoregon.technologypublisher.com/technology/59765</link><description><![CDATA[1. Technology Overview&nbsp;

The invention presents an innovative electrochemical cell design for producing iron metal from iron oxide powders and salt water. This technology leverages low-cost and abundant raw materials to produce high-purity iron, while co-producing valuable byproducts such as chlorine and sodium hydroxide. The process is highly efficient, scalable, and environmentally friendly, offering a sustainable alternative to traditional iron production methods. Currently in the development stage, this technology holds significant potential for cross-industry applications in steel ma...]]></description><pubDate>Fri, 02 Jan 2026 15:33:23 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59765</guid></item><item><title>Electrochemical Process for the Continuous Co-production of Iron and Chlorine Gas</title><caseId>UO-22-032</caseId><link>http://icoregon.technologypublisher.com/technology/59764</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces an innovative electrochemical process for the continuous co-production of iron and chlorine gas, known as the &quot;Chlor-Iron process.&quot; This technology&nbsp;leverages&nbsp;a low-temperature reactor powered by renewable electricity to produce iron metal and chlorine gas from iron ore and concentrated seawater. The process is highly efficient, scalable, and environmentally friendly, offering a sustainable alternative to traditional iron production methods. Currently in the development stage, this technology holds significant potential ...]]></description><pubDate>Fri, 02 Jan 2026 15:30:14 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59764</guid></item><item><title>Walking and Running Prosthesis (WARP)</title><caseId>UO-17-24</caseId><link>http://icoregon.technologypublisher.com/technology/59763</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on a versatile lower limb prosthesis, named Walking and Running Prosthesis (WARP), designed to improve locomotion across both low-impact walking and higher-impact running tasks. The prosthesis actively varies its properties to match different tasks, using semi-active actuation to&nbsp;modify&nbsp;its structure without requiring human-scale power input. The technology is currently in the development stage, with promising cross-industry applications in prosthetics, rehabilitation, and sports equipment.&nbsp;

2. Key Features and Benefits&nbsp;
...]]></description><pubDate>Fri, 02 Jan 2026 15:24:19 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59763</guid></item><item><title>Diindenoanthracene and Diindenopentacene</title><caseId>UO-15-20</caseId><link>http://icoregon.technologypublisher.com/technology/59762</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on&nbsp;diindenoanthracene&nbsp;(DIAn), a novel compound featuring mild biradical character with potential applications in singlet fission for organic photovoltaics and organic spin electronics.&nbsp;DIAn&nbsp;is designed with bulky mesityl and&nbsp;triisopropylsilylacetylene&nbsp;groups to stabilize reactive sites and prevent intermolecular decomposition. The technology is currently in the development stage, with promising cross-industry applications in organic photovoltaics, spin electronics, and material science.&nbsp;

2. Key Features and...]]></description><pubDate>Fri, 02 Jan 2026 14:18:52 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59762</guid></item><item><title>Malassezia-Secreted Factor with Antibiotic Activity</title><caseId>UO-21-029</caseId><link>http://icoregon.technologypublisher.com/technology/59761</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel antimicrobial activity produced by human-associated fungi, specifically Malassezia&nbsp;sympodialis, for potential development as antibiotics. The secreted factor&nbsp;exhibits&nbsp;bactericidal activity against Staphylococcus aureus and enhances bacterial sensitivity to other antibiotics, making it suitable for combination therapy. The technology leverages&nbsp;established&nbsp;microbiological and genetic techniques, offering significant potential for applications in antibiotic development, biotechnology, and clinical diagnostics....]]></description><pubDate>Fri, 02 Jan 2026 14:14:01 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59761</guid></item><item><title>Mechanical Quantum Networks of Spin Qubits with Long Range Connectivity</title><caseId>UO-25-006</caseId><link>http://icoregon.technologypublisher.com/technology/59760</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a groundbreaking method for developing mechanical quantum networks of spin qubits with long-range connectivity using&nbsp;Wannier-Stark ladders of diamond Lamb wave resonators (LWRs). This innovative approach&nbsp;leverages&nbsp;the ultralow damping rates and excellent optical and spin properties of diamond LWRs to create robust and scalable quantum networks. Currently in the development stage, this technology holds significant potential for cross-industry applications in quantum computing, communication, and advanced materials.&nbsp;

2. ...]]></description><pubDate>Fri, 02 Jan 2026 14:10:22 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59760</guid></item><item><title>Moderate-Affinity Affibodies for Controlled Protein Delivery and Bioactivity</title><caseId>UO-22-057</caseId><link>http://icoregon.technologypublisher.com/technology/59759</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel method for controlled protein delivery and bioactivity using&nbsp;moderate-affinity&nbsp;affibodies. These 58-amino acid peptides can specifically bind to various proteins, allowing for the controlled release or sequestration of multiple payloads within a single vehicle. The technology&nbsp;leverages&nbsp;the conjugation of affibodies to hydrogel vehicles, enabling&nbsp;the independent&nbsp;control of protein release rates. This innovative approach offers significant potential for applications in drug delivery, tissue engineering, ...]]></description><pubDate>Fri, 02 Jan 2026 14:10:12 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59759</guid></item><item><title>Resonant Excitation of Compression Mechanical Modes in a Mechanical Resonator with an Optical Gradient Force</title><caseId>UO-24-053</caseId><link>http://icoregon.technologypublisher.com/technology/59758</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces&nbsp;ultracoherent&nbsp;GHz diamond spin-mechanical Lamb wave resonators (LWRs) protected by a&nbsp;phononic&nbsp;band gap. These resonators enable coherent interactions between single phonons and spins, providing a robust platform for quantum spin-mechanics. The technology leverages all-optical excitation and detection methods, ensuring high performance and scalability. Currently in the development stage, this technology holds significant potential for cross-industry applications in quantum computing, communication, and advanced materials...]]></description><pubDate>Fri, 02 Jan 2026 13:55:31 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59758</guid></item><item><title>3D-printed Ion Trap</title><caseId>UO-22-003</caseId><link>http://icoregon.technologypublisher.com/technology/59757</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a 3D-printed ion trap designed for quantum computing applications. This innovative device&nbsp;leverages&nbsp;additive 3D printing of glass structures to create ion traps that can be integrated onto wafers&nbsp;containing&nbsp;micro-fabricated elements. The technology offers significant potential for improving trapping efficiency, depth, and harmonicity compared to traditional 2D surface-electrode traps. Currently in the development stage, this technology holds strong potential for commercialization in quantum computing, semiconductor manu...]]></description><pubDate>Fri, 02 Jan 2026 13:45:37 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59757</guid></item><item><title>Polyfunctional Silica Material</title><caseId>UO-17-01</caseId><link>http://icoregon.technologypublisher.com/technology/59756</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on the recovery and collection of rare earth elements (REEs) from natural waters and geothermal brines using nanostructured sorbents. These sorbents are functionalized with ligands such as&nbsp;diphosphonic&nbsp;acid (DiPhos), propionamide phosphonic acid (PropPhos), and iminodiacetic acid (IDAA) to enhance their affinity and selectivity for REEs. The technology is currently in the development stage, with promising cross-industry applications in water treatment, mining, and environmental monitoring.&nbsp;

2. Key Features and Benefits&nbsp;

...]]></description><pubDate>Fri, 02 Jan 2026 13:32:06 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59756</guid></item><item><title>Anisotropic Poly(ethylene glycol)-Based Hydrogels Synthesized via Two-Stage Polymerization and Mechanical Alignment</title><caseId>UO-24-010</caseId><link>http://icoregon.technologypublisher.com/technology/59755</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces synthetic&nbsp;poly(ethylene glycol)-based hydrogels with anisotropic polymer network topology, mimicking the structure of musculoskeletal tissues. These hydrogels are synthesized using a two-stage polymerization process, allowing for the application of mechanical force to impart anisotropy. The technology also enables the encapsulation of&nbsp;cells for tissue regeneration applications. Currently in the development stage, this technology holds significant potential for cross-industry applications in tissue engineering, regenerative medici...]]></description><pubDate>Fri, 02 Jan 2026 13:26:18 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59755</guid></item><item><title>Anion Sensing with nanoMOF Electrodes</title><caseId>UO-23-028</caseId><link>http://icoregon.technologypublisher.com/technology/59754</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel method for selective anion sensing using chromium&nbsp;triazolate&nbsp;metal-organic framework (MOF) nanocrystals. These nanocrystals enable the detection of&nbsp;anion&nbsp;identity and concentration through&nbsp;voltammetric&nbsp;sweeping, offering high selectivity, sensitivity, and reusability. The technology leverages electrochemical manipulation of anion intercalation and de-intercalation processes, making it suitable for various applications in environmental monitoring, biomedical diagnostics, and industrial safety. Currently...]]></description><pubDate>Fri, 02 Jan 2026 13:20:21 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59754</guid></item><item><title>Small MOF Particles</title><caseId>UO-21-022</caseId><link>http://icoregon.technologypublisher.com/technology/59753</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces nanoparticles of 1,2,3-triazolate metal-organic frameworks (MOFs) with varying metal ions, offering a scalable and cost-effective solution for creating high-quality thin films. These nanoparticles are synthesized using solution processing methods, allowing for the formation of small and/or monodisperse nanomaterials. The technology holds significant potential for applications in electrocatalysis, ion sensing, and advanced materials, providing enhanced performance and scalability. Currently in the development stage, this technology is poise...]]></description><pubDate>Fri, 02 Jan 2026 13:15:08 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59753</guid></item><item><title>A Fast, Broadband, Room-temperature Graphene Nanomechanical Light Detector</title><caseId>UO-18-33</caseId><link>http://icoregon.technologypublisher.com/technology/59752</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on a fast, broadband, room-temperature graphene nanomechanical light detector. This device detects light by measuring shifts in the mechanical resonance of suspended graphene, which changes its pitch when it absorbs light and warms up. The technology is currently in the development stage, with promising cross-industry applications in imaging, spectroscopy, environmental monitoring, and medical diagnostics.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Broadband Sensitivity: Detects a wide range of light, including the blind spot.&nbsp;
	



...]]></description><pubDate>Fri, 02 Jan 2026 11:22:25 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59752</guid></item><item><title>Non-Linear Single-Molecule FRET</title><caseId>UO-22-002</caseId><link>http://icoregon.technologypublisher.com/technology/59729</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel method for measuring the relative orientation of donor-acceptor (D-A) pairs in fluorescence resonance energy transfer (FRET) microscopy. This method&nbsp;leverages&nbsp;non-linear spectroscopy and phase-tagged photon counting to achieve precise measurements of the relative orientation and distance between D-A pairs. The technology offers significant potential for applications in molecular biology, biophysics, medical diagnostics, and pharmaceutical research. Currently in the development stage, this technology holds strong potential...]]></description><pubDate>Wed, 31 Dec 2025 13:07:11 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/59729</guid></item><item><title>A photocrosslinkable bone derived biomaterial for tissue engineering applications</title><caseId>2875</caseId><link>http://icoregon.technologypublisher.com/technology/58072</link><description><![CDATA[
Summary

Demineralized bone matrix has been widely used in the clinic to heal bone injuries due to its remarkable regenerative properties. However, this is not a material that can be synthesized in large batches, with highly reproducible chemistry, and cannot be set/polymerized in-situ for precise adaptation.&nbsp; BoneMA is photopolymerizable material that is primarily composed of the bone extracellular matrix and is amenable to in situ polymerization. It also has been show to be more angiogenic and vasculogenic than other hydrogels in the field, while being amendable to controllable loading...]]></description><pubDate>Wed, 23 Jul 2025 15:27:34 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/58072</guid></item><item><title>Micro-channels, Micro-mixers and Micro-reactors</title><caseId>OSU-12-09</caseId><link>http://icoregon.technologypublisher.com/technology/57661</link><description><![CDATA[Microreactor architectures for mixing, reactions, and/or heat exchange 

Background   
Microfluidic systems and micro-reactors have emerged as promising platforms for precise, small-scale fluid processing. Microfluidic systems offer reduced reagent use, enhanced control over reaction kinetics, and improved safety through process intensification. However, efficient mixing of immiscible fluids or fluids of differing viscosities remains challenging.

Conventional micromixers often fail to achieve sufficient mass transfer across fluid interfaces&mdash;particularly when mixing liquids with contrast...]]></description><pubDate>Mon, 23 Jun 2025 15:30:26 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/57661</guid></item><item><title>Novel Line-of-Sight RF Signal Classification Method</title><caseId>OSU-24-37</caseId><link>http://icoregon.technologypublisher.com/technology/57633</link><description>This is a method for classifying Line-of-Sight (LOS) and Non-Line-of-Sight (NLOS) conditions in radio frequency (RF) communication 

Background   
Indoor positioning systems struggle with accurately identifying LOS and NLOS signal conditions ‑ a critical capability since most localization algorithms assume the presence of a direct signal path. However, indoor environments introduce numerous obstacles, leading to multipath propagation that distorts signal characteristics. Traditional classification approaches are hindered by high computational demands, sensitivity to environmental changes, or r...</description><pubDate>Wed, 18 Jun 2025 13:21:17 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/57633</guid></item><item><title>Atomically Smooth Nanoporous Alumina Thin Films</title><caseId>OSU-16-08</caseId><link>http://icoregon.technologypublisher.com/technology/56009</link><description>A novel method of producing near-atomically smooth and porous alumina thin films with a tunable index of refraction 

Background   
Typically, high quality thin films are produced via vacuum-based techniques, though the nature of this technique makes it difficult to produce porous films. In lieu of vacuum techniques, solution processing is a low-energy alternative to thin-film deposition. To manufacture porous thin films by solution processing, sol-gel precursors have received much attention. However, these precursors foster nanoparticle formation due to their highly reactive ligands, typicall...</description><pubDate>Fri, 17 Jan 2025 13:06:09 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/56009</guid></item><item><title>Method for Rapid Fabrication of Microfluidic Analytical Devices</title><caseId>OSU-20-17</caseId><link>http://icoregon.technologypublisher.com/technology/56005</link><description>A rapid two-step fabrication method for 2D, 3D, and enclosed microfluidic devices using porous-media materials and polymeric films 

Background   
Microfluidic analytical devices are widely used in various clinical, diagnostic, and forensic applications, and can be used in the field to test for analytes of interest. Most current methods for the fabrication of porous substrate microfluidic devices utilize techniques to create barriers within the substrates by using hydrophobic materials. These methods can often be expensive and time-consuming, requiring layers of the device to be formed separat...</description><pubDate>Fri, 17 Jan 2025 10:41:55 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/56005</guid></item><item><title>Phage Bank for Selection of Personalized Therapeutic Treatments against Mycobacteria</title><caseId>OSU-19-60</caseId><link>http://icoregon.technologypublisher.com/technology/56004</link><description>A phage bank comprising lytic phages against mycobacteria, used to create phage cocktails for treatment of drug-resistant infections 

Background   
Non‑tuberculous mycobacteria (NTM) pathogens are extremely antibiotic resistant causing the most difficult-to-treat pulmonary infections in immunocompromised individuals such are cystic fibrosis (CF), bronchiectasis, emphysema, and in patients with prior tuberculosis. NTM incidents have been increasing worldwide in recent years leading to high morbidity and fatality rates. While clinically available antibiotics effectively kill NTM in vitro, despi...</description><pubDate>Fri, 17 Jan 2025 10:13:48 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/56004</guid></item><item><title>Selective Modulators of Ah-R to Treat Cancer</title><caseId>OSU-21-48</caseId><link>http://icoregon.technologypublisher.com/technology/55949</link><description>Synergistic compositions and method of using modulators of Ah-R activity and synergistic compounds to treat cancer 

Background   
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. When activated by the binding of a wide range of both endogenous and exogenous small molecules, AhR signaling influences cellular outcomes in different developmental, immunological, and cancer-related contexts. Once activated, AhR translocates from the cytosol into the nucleus and heterodimerizes with AhR Nuclear Translocator (ARNT). Binding of the AhR/ARNT complex to specific promoter sequ...</description><pubDate>Wed, 08 Jan 2025 09:59:03 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55949</guid></item><item><title>Personalized type 1 diabetes decision support using digital twins</title><caseId>3305</caseId><link>http://icoregon.technologypublisher.com/technology/55717</link><description><![CDATA[Summary
The current technology is the first decision support tool for type 1 diabetes that provides personalized recommendations based on digital twin simulations and accounts for variables such as carbohydrate consumption, exercise, and nighttime risk of hypoglycemia.

Technology Overview
Managing glucose levels is challenging for individuals with type 1 diabetes (T1D) since multiple factors can impact an individual&rsquo;s insulin sensitivity. Current decision support tools lack personalized recommendations and fail to account for factors like exercise and meal consumption that can alter ins...]]></description><pubDate>Tue, 03 Dec 2024 07:03:14 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/55717</guid></item><item><title>Malaria transmission blocking using ELQ-infused bed nets</title><caseId>3147</caseId><link>http://icoregon.technologypublisher.com/technology/55348</link><description><![CDATA[Summary
Insecticide-treated mosquito bed nets reduce the transmission of malaria, but mosquitos have developed resistance to insecticides leading to reduced efficacy.&nbsp; Our new technology is a chemical solution for mosquito nets that kills malaria, is less prone to drug-resistance and is not toxic to humans. 

Technology Overview
Insecticide-treated mosquito bed nets are an effective strategy to decrease the spread of malaria. However, insecticides can be toxic to humans, and mosquitoes have developed resistance to these compounds over time. Additionally, drug resistance developed by the m...]]></description><pubDate>Tue, 15 Oct 2024 09:28:44 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/55348</guid></item><item><title>UVsynC: a sterilization drain cover for hospital sinks</title><caseId>3300</caseId><link>http://icoregon.technologypublisher.com/technology/55292</link><description><![CDATA[Summary
The current technology is designed to limit the growth and spread of drug-resistant pathogens in hospitals by providing a UV-C LED Pathogen mitigation drain cover device for hospital sinks.&nbsp; The device is a drain cap that can be quickly installed on hospital sinks and provides effective control of biofilm growth than current solutions. 

Technology Overview
Patients staying in hospital are at risk of infection from multiple different drug-resistant pathogens, which can cause significant health complications. These pathogens can build up in the biofilm of hospital sinks, particular...]]></description><pubDate>Tue, 08 Oct 2024 08:25:14 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/55292</guid></item><item><title>A Low-power Magnetorheological Fluid Clutch</title><caseId>OSU-23-14</caseId><link>http://icoregon.technologypublisher.com/technology/55055</link><description>This clutch device enables low-power, rapid, and reversible actuation of soft robotic devices to improve physical human-robot interactions

Background 
Common implementations of soft robotics and compliant mechanisms utilize deformable materials, such as silicone or other elastomers, in their designs. Flexibility and elasticity improve overall compliance, but constructing robots from these materials often limits the overall strength and speed of a robot. This smart material clutch enables several control strategies, improving physical human robot interactions through variable stiffness joints ...</description><pubDate>Thu, 05 Sep 2024 10:56:07 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55055</guid></item><item><title>Enhancing Methotrexate Efficacy for Ectopic Pregnancy Treatment</title><caseId>OSU-23-13</caseId><link>http://icoregon.technologypublisher.com/technology/55054</link><description>Methotrexate (MTX) loaded polymersomes are used to preferentially deliver MTX to sites of ectopic pregnancy 

Background   
Ectopic pregnancy, abnormal pregnancy implantation at sites other than in the uterine cavity, leads to internal bleeding if not identified and treated in a timely manner, and is a major cause of maternal morbidity and mortality. Accounting for about 1-2% of pregnancies in the United States, ectopic pregnancy is normally treated using a systemic administration of methotrexate (MTX). However, the failure rate of MTX treatment can exceed 10%. The risk factors of such failure...</description><pubDate>Thu, 05 Sep 2024 10:55:59 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55054</guid></item><item><title>SUCCESSOR™ Barley (DH1190481)</title><caseId>OSU-23-12</caseId><link>http://icoregon.technologypublisher.com/technology/55053</link><description><![CDATA[Features &amp; Benefits    


	Growth habit: spring
	Hull type: covered
	Awn type: awned
	Principal end use: feed


Status    
Please go to Barley World for more information about license details.]]></description><pubDate>Thu, 05 Sep 2024 10:55:51 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55053</guid></item><item><title>Shoot Inducing Genes for Improved Production of Transgenic Plants</title><caseId>OSU-23-11</caseId><link>http://icoregon.technologypublisher.com/technology/55052</link><description>This invention, using Agrobacterium gene clusters, enables passive regeneration of transgenic cells without the need for plant hormones

Background   
For plants which are recalcitrant (difficult) to transform, poor performance is usually associated with inadequate DNA delivery or difficult regeneration response. There is a need for improved methods of reducing transgenic plants.

Production of transgenic plants requires the delivery of foreign DNA, and subsequent regeneration of cells with delivered DNA into intact plants. Typical regeneration methods utilize chemical hormone treatments in st...</description><pubDate>Thu, 05 Sep 2024 10:55:43 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55052</guid></item><item><title>Improved Lox SItes for Cre Recombination Plants</title><caseId>OSU-23-07</caseId><link>http://icoregon.technologypublisher.com/technology/55051</link><description>Provides recombination sites for the most widely used recombinase that facilitate increased plant activity

Background   
Site-specific recombinases are widely used molecular tools for performing DNA manipulations both in vitro and in vivo, with applications in research and biotechnology. This includes deletion, integration, and inversion of target sequences of interest. Cre acts upon recognition sequences which are called lox sites, the most widely used of which is loxP, which is naturally present in the phage P1 genome. The inventors developed novel lox sequences, and a method for generating...</description><pubDate>Thu, 05 Sep 2024 10:55:25 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55051</guid></item><item><title>Hibiscus syriacus ‘ORSTHIB5x1’ - "Petite Pink Flamingo ™"</title><caseId>OSU-23-02</caseId><link>http://icoregon.technologypublisher.com/technology/55050</link><description>

Features


	Seedless pentaploid selection
	Single pink flowers produced in large numbers
	Dark green foliage early in the season 
	Upright and vigorous, but compact growth habit


Status


	Plant patent application pending
	Available for non-exclusive license
</description><pubDate>Thu, 05 Sep 2024 10:55:08 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/55050</guid></item><item><title>Combination therapy for the treatment of triple negative breast cancer</title><caseId>3234</caseId><link>http://icoregon.technologypublisher.com/technology/54964</link><description><![CDATA[Summary
Researchers at OHSU have discovered a novel combination therapy for triple negative breast cancer, which increases immune responses, causes tumor regression and improves survival in animal models. &nbsp;

Technology Overview
Triple negative breast cancer (TNBC) represents one of the most aggressive forms of all breast cancer subtypes with a very high rate of recurrence. A recently approved immune checkpoint inhibitors (ICI) for TNBC patients increases median overall survival by ~7 months. However, median overall survival is still under two years even with the use of ICI and 50% of TNBC...]]></description><pubDate>Thu, 22 Aug 2024 12:46:17 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/54964</guid></item><item><title>Machine-learning based forecasting of visual field deficits for glaucoma management</title><caseId>3321</caseId><link>http://icoregon.technologypublisher.com/technology/54908</link><description>Summary
The current technology is a machine learning algorithm that can accurately forecast glaucoma-induced visual field deficits and outperforms existing forecasting methods. This technology could allow for more efficient management of glaucoma by reducing the number of office-based visual field assessments.

Technology Overview
Glaucoma is characterized by a progressive loss of the visual field (VF). As such, physicians currently rely on frequent office-based testing of the VF to monitoring these patients. Conventional VF trend analysis requires a minimum of three previous VF assessments an...</description><pubDate>Thu, 15 Aug 2024 07:24:28 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/54908</guid></item><item><title>Protease Activity Sensing Probes For Early Detection and Prognosis of Pancreatic Cancer</title><caseId>3213</caseId><link>http://icoregon.technologypublisher.com/technology/54797</link><description><![CDATA[Summary
The current technology is a liquid biopsy diagnostic screen for pancreatic ductal adenocarcinoma (PDAC), which is high throughput, requires very small blood volumes and has been validated in a large patient dataset.&nbsp; 

Technology Overview
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers and is typically discovered by accident since there are few approved detection methods. Early detection of cancer through liquid biopsy diagnostics greatly improves patient prognosis and survival rates.&nbsp; However, current detection of PDAC through evaluation of CA19-9 lev...]]></description><pubDate>Wed, 31 Jul 2024 08:50:40 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/54797</guid></item><item><title>USDA Blueberry 'Mini Blues'</title><caseId>EXT-13-10</caseId><link>http://icoregon.technologypublisher.com/technology/54693</link><description><![CDATA[Technology Description
&lsquo;Mini Blues&rsquo; is a blueberry clone distinguished by its high yield of very small fruit that can be harvested by machine, has excellent flavor, and is well suited to the processed fruit industry on a bush that is vigorous and upright. This new blueberry cultivar was discovered in Corvallis, Oregon in July 1999 and originated from a cross between the female blueberry plant &lsquo;US 647&rsquo; (unpatented) and the male blueberry parent &lsquo;US 645&rsquo; (unpatented); the cross was made in East Lansing, MI. The original seedling of the new cultivar was asexual...]]></description><pubDate>Fri, 19 Jul 2024 13:49:19 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54693</guid></item><item><title>USDA Blackberry 'Columbia Sunrise'</title><caseId>EXT-13-11</caseId><link>http://icoregon.technologypublisher.com/technology/54692</link><description><![CDATA[Technology Description
&lsquo;Columbia Sunrise&rsquo; is the earliest ripening thornless blackberry currently on the market. It has very good yields of medium sized well-formed fruit that taste good. &lsquo;Columbia Sunrise&rsquo; can be machine harvested for the processed market. The early ripening characteristic gives fresh market growers an extended season and processed growers a cultivar option that, due to its early ripening, will need fewer insecticide applications for spotted winged drosophila.

Features &amp; Benefits    


	Thornless cultivar that ripens 10-14 d before current earlies...]]></description><pubDate>Fri, 19 Jul 2024 13:47:04 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54692</guid></item><item><title>USDA Blueberry 'Echo'</title><caseId>EXT-13-13</caseId><link>http://icoregon.technologypublisher.com/technology/54690</link><description><![CDATA[Technology Description
Repeat flowering and fruiting in blueberry is unusual in northern temperate climates. &lsquo;Perpetua&rsquo; was the first of these sorts to be released and &lsquo;Echo&rsquo; is an offspring of &lsquo;Perpetua&rsquo;. &lsquo;Echo&rsquo; has a relatively small crop in spring and a larger crop in late summer. The combination of attractive foliage, fruit, and flowers at a time in the season where there is really nothing like it is appealing. It is an attractive ornamental year round and should be especially suited to summer nursery sales when the plant is particularly attr...]]></description><pubDate>Fri, 19 Jul 2024 13:44:46 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54690</guid></item><item><title>USDA Strawberry 'Mary's Peak'</title><caseId>EXT-13-12</caseId><link>http://icoregon.technologypublisher.com/technology/54689</link><description><![CDATA[Technology Description
&#39;Marys Peak&#39; is a high yielding strawberry that is suited to production in perennial matter row systems. The plants are vigorous and open. This plant architecture combined with large and firm fruit and high yields make &lsquo;Marys Peak&rsquo; very efficient to pick and desirable to harvest labor. The fruit are firm with good internal and external color. While suited for wholesale fresh market sales, it will be primarily grown for thee processing market. The fruit have very good flavor and have very good quality after being frozen and thawed. 

Features &amp; Ben...]]></description><pubDate>Fri, 19 Jul 2024 13:44:36 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54689</guid></item><item><title>USDA Blackberry 'Hall's Beauty'</title><caseId>EXT-13-14</caseId><link>http://icoregon.technologypublisher.com/technology/54688</link><description><![CDATA[Technology Description
&lsquo;Hall&rsquo;s Beauty&rsquo;, tested as ORUS 3453-2, was selected in Corvallis, Ore. in 2008 from a cross made in 2005 of NZ 9629R-1 (NZ 9336FI.0 x NZ 9256RHB.4) and ORUS 1939-2 (NW 8832-1 [NZ 8316I21 {&lsquo;Boysen&rsquo; x &lsquo;Marion&rsquo;} x &lsquo;Waldo&rsquo;] x &lsquo;Siskiyou&rsquo;). &lsquo;Hall&rsquo;s Beauty&rsquo; carries the &lsquo;Lincoln Logan&rsquo; source of thornlessness. A U.S. Patent application has been filed.

Features &amp; Benefits    


	High quality and early ripening fruit with excellent flavor
	Very attractive, large, double-petaled fl...]]></description><pubDate>Fri, 19 Jul 2024 13:40:33 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54688</guid></item><item><title>USDA Red Raspberry 'Kokanee'</title><caseId>EXT-13-09</caseId><link>http://icoregon.technologypublisher.com/technology/54687</link><description><![CDATA[Technology Description
Oregon State University is seeking to commercialize &lsquo;Kokanee&rsquo; a new red raspberry cultivar that was jointly developed by the OSU Department of Horticulture and the USDA Agricultural Research Service. &lsquo;Kokanee&rsquo; is a primocane fruiting (fall fruiting; everbearing) type raspberry that produces bright red, colorful, sweet and flavorful fruit that are suitable for local and wholesale fresh market. Yields and fruit quality have been evaluated extensively in observation plots and commercial plantings. In addition to production in the Pacific Northwest, &...]]></description><pubDate>Fri, 19 Jul 2024 13:36:39 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54687</guid></item><item><title>USDA Blackberry 'Columbia Giant'</title><caseId>EXT-13-08</caseId><link>http://icoregon.technologypublisher.com/technology/54686</link><description><![CDATA[Technology Description
The most outstanding characteristics of &lsquo;Columbia Giant&rsquo; are its good yields of extremely large well- formed fruit. The fruit quality is excellent for fresh due to its visual appeal. The extremely large size, over 12 g, can make packaging in clam shells for fresh market problematic but the size is very positive for local retail sales or if specialized packaging is used. &lsquo;Columbia Giant&rsquo;, is thornless and can be machine harvested for a high quality processed product.

Features &amp; Benefits    


	Obscenely large, attractive fruit
	Uniformly sized...]]></description><pubDate>Fri, 19 Jul 2024 13:23:32 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54686</guid></item><item><title>USDA Strawberry 'Charm'</title><caseId>EXT-13-07</caseId><link>http://icoregon.technologypublisher.com/technology/54685</link><description><![CDATA[Technology Description
CHARM has held up well with excellent yields in the second harvest season and therefore was assumed to be relatively tolerant to viruses. The most outstanding characteristics of CHARM are its high yield of easily harvested fruit with excellent flavor that were well adapted to diverse and trying locations. The fruit also has a full, balanced sweet-to-acid strawberry flavor.

Features &amp; Benefits    


	High yielding cultivar
	Easily capped
	Particularly well suited for ice cream formulations
	Tolerant for viruses
	Excellent flavor


Applications    


	Fresh fruit mark...]]></description><pubDate>Fri, 19 Jul 2024 13:12:37 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54685</guid></item><item><title>USDA Strawberry 'Sweet Sunrise'</title><caseId>EXT-13-06</caseId><link>http://icoregon.technologypublisher.com/technology/54684</link><description><![CDATA[Technology Description
Sweet Sunrise is a high yielding cultivar that has been successfully tested in multiple trials in Oregon as well as Washington and British Columbia. The strawberry has scored well in subjective evaluations of fresh fruit characteristics and as a processed fruit. Sweet Sunrise has a full, and balanced sweet-to-acid strawberry flavor with a deep red internal color.

Features &amp; Benefits    


	High yielding cultivar
	High quality processed fruit
	Full, balanced sweet-to-acid strawberry flavor
	Ripening in the early midseason


Applications   


	Fresh fruit market
	Proc...]]></description><pubDate>Fri, 19 Jul 2024 13:11:04 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54684</guid></item><item><title>USDA Blackberry 'Columbia Star'</title><caseId>EXT-13-05</caseId><link>http://icoregon.technologypublisher.com/technology/54683</link><description><![CDATA[Technology Description
Oregon State University is seeking to commercialize the Columbia Star Blackberry. In a collaboration between the USDA-Agricultural Research Service, the Oregon Agricultural Experiment Station and the Washington Agricultural Research, they have created a thornless, machine harvestable, high quality blackberry for the processed fruit market. The plant has been harvested using an over-the-row machine in trials in Oregon and Washington and has performed extremely well. Columbia Star is the first commercial blackberry-type cultivar to be released using the &lsquo;Lincoln Loga...]]></description><pubDate>Fri, 19 Jul 2024 13:02:28 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54683</guid></item><item><title>USDA Red Raspberry 'Vintage'</title><caseId>EXT-13-03</caseId><link>http://icoregon.technologypublisher.com/technology/54680</link><description>Technology Description
Oregon State University is seeking to commercialize Vintage, a new raspberry cultivar. Jointly developed by the OSU Horticulture department and USDA Agricultural Research Service, Vintage yields bright red colored, sweet, flavorful fruit that is suitable for local and wholesale fresh market. Yields and fruit quality have been evaluated extensively in observation plots and commercial orchards. Fruit characteristics such as color, flavor, texture and firmness of Vintage were evaluated against a commercially comparable variety, Heritage. Vintage berries were found to have b...</description><pubDate>Fri, 19 Jul 2024 12:47:24 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54680</guid></item><item><title>USDA Blackberry 'Onyx'</title><caseId>EXT-13-02</caseId><link>http://icoregon.technologypublisher.com/technology/54679</link><description>Technology Description
Oregon State University is seeking to commercialize Onyx, a new blackberry hybrid plant. Jointly developed by the OSU Horticulture department and USDA Agricultural Research Service, Onyx yields firm, sweet, and high quality fruit that is suitable for local and wholesale fresh market. Yields and berry quality have been evaluated extensively in observation plots and commercial orchards. In these trials, berry yield and berry weight of Onyx were better than or comparable to the yield and weight of two other commercially available blackberry plants. When compared to the comm...</description><pubDate>Fri, 19 Jul 2024 12:40:25 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54679</guid></item><item><title>TOP SHELF™ Barley (DH162310)</title><caseId>OSU-24-02</caseId><link>http://icoregon.technologypublisher.com/technology/54635</link><description><![CDATA[Features &amp; Benefits    


	Growth habit: winter
	Hull type: covered
	Awn type: awned
	Principal end use: malt


Status    
Please go to Barley World for more information about license details.]]></description><pubDate>Thu, 11 Jul 2024 16:13:56 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54635</guid></item><item><title>OREGON PROMISE™ Barley (DH120285)</title><caseId>OSU-20-53</caseId><link>http://icoregon.technologypublisher.com/technology/54634</link><description><![CDATA[Features &amp; Benefits    


	Growth habit: spring
	Hull type: covered
	Awn type: awned
	Principal end use: malt


Status    
Please go to Barley World for more information about license details.]]></description><pubDate>Thu, 11 Jul 2024 16:11:22 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54634</guid></item><item><title>LONTRA™ Barley (DH142010)</title><caseId>OSU-23-21</caseId><link>http://icoregon.technologypublisher.com/technology/54633</link><description><![CDATA[Features &amp; Benefits    


	Growth habit: winter
	Hull type: covered
	Awn type: awned
	Principal end use(s) in order of priority: malt, feed, food


Status    
Please go to Barley World for more information about license details.]]></description><pubDate>Thu, 11 Jul 2024 15:59:08 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54633</guid></item><item><title>5th Amendment to A Radio-Frequency-Free Hybrid Electrostatic/ Magnetostatic Cell for Transporting, Trapping, and Dissociating Ions in Mass Spectrometers - Internal Electron Source Configurations</title><caseId>OSU-11-55</caseId><link>http://icoregon.technologypublisher.com/technology/54441</link><description>Background   
The need to identify complex molecules in real-world samples has propelled mass spectrometry into a $3 billion industry growing 8% annually. The fragmentation of molecules within a mass spectrometer is necessary to accurately reveal their identity. The current approach uses a sledgehammer that complicates identification. Our technology uses low-energy electrons as a scalpel to cut molecules with precision. We switch between three complementary methods of fragmentation in milliseconds to correctly identify molecules as large as whole proteins. These methods are well established bu...</description><pubDate>Mon, 17 Jun 2024 17:15:14 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54441</guid></item><item><title>Fabrication of Polycaprolactone (PCL) Microfluidic chips, Interconnects, and Microdevices</title><caseId>OSU-11-28</caseId><link>http://icoregon.technologypublisher.com/technology/54440</link><description>Technology Description    
This technology describes using uniformly thin polycaprolactone coated polymer as a bonding agent to enclose various microchannels made with hard polymer, including but not limited to PMMA,PC, PEI and PETE.

The technology could also be applied to connect any hard polymer ports/headers to the aforementioned microchannels. The convenient, low cost and versatility technique makes it useful for both rapid prototyping and mass production of polymer-based microfluidic devices operating at ambient temperature that could withstand 1,500 psi. 

Status    
Patented US 8,999,2...</description><pubDate>Mon, 17 Jun 2024 16:53:40 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54440</guid></item><item><title>Active Force Control of Inherent Passive Dynamics</title><caseId>OSU-10-46</caseId><link>http://icoregon.technologypublisher.com/technology/54439</link><description>Background   
Unlike moving animals, current robots do not maintain sufficient energy efficiency and robustness to (ground) disturbances. Current energy efficient passive walkers fail to handle minor disturbances in walking surface, whereas robotic solutions incorporating active control are robust to disturbances, yet inadequate in energy consumption. This technology addresses this problem with optimal performance in both respects, similar to animals (and us humans) which utilize passive dynamics with active force control. In general, this technology improves the physical function and efficien...</description><pubDate>Mon, 17 Jun 2024 16:49:36 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54439</guid></item><item><title>Inhibitors of Transporters or Uptake of Monoaminergic Neurotransmitters</title><caseId>OSU-06-07</caseId><link>http://icoregon.technologypublisher.com/technology/54436</link><description>Background   
One form of medical treatment for depression and neuropathic pain features a dual inhibitor called Cymbalta. This drug is manufactured and marketed by Eli Lilly. Researchers at Oregon State University have discovered a very efficient way of synthesizing Synosutine, which is comparable to Cymbalta in limited in vitro and in vivo assay. This drug could have powerful implications for treatment of depression and neuropathic pain. 

Technology Description    
This technology is a simple and efficient way for synthesizing Synosutine, a drug to be potentially used to treat depression an...</description><pubDate>Mon, 17 Jun 2024 14:30:17 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54436</guid></item><item><title>Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues</title><caseId>OSU-23-25</caseId><link>http://icoregon.technologypublisher.com/technology/54312</link><description><![CDATA[A nanocarrier system to effectively deliver anti-inflammatory drugs and improve the treatment of inflammatory diseases 

Background   
The inflammatory response is the body&rsquo;s natural defense mechanism against infection and injury. In certain instances, however, persistent and uncontrolled inflammation becomes detrimental and contributes to the development and progression of various debilitating diseases, including cancer, atherosclerosis, autoimmune and neurodegenerative disorders. Anti-inflammatory drugs are considered a viable strategy for preventing and treating inflammation. However,...]]></description><pubDate>Thu, 30 May 2024 18:03:35 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54312</guid></item><item><title>Microbial Electrosynthesis of Single Cell Protein</title><caseId>OSU-22-38</caseId><link>http://icoregon.technologypublisher.com/technology/54309</link><description>This technology uses a microbial electrolysis cell to consume organic waste and produce high quality single cell protein 

Background   
As population growth continues, the world is increasingly deficient in high quality protein. Most protein is produced from an inefficient industrial agriculture system that depletes natural resources and stresses arable land while contributing to climate change. We are in need of technologies that produce protein more efficiently, with less water and arable land, while producing less waste and mitigating climate impacts. Single cell protein is an attractive s...</description><pubDate>Thu, 30 May 2024 16:43:41 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54309</guid></item><item><title>Growth Factor Loaded Nanofibers for Wound Healing</title><caseId>OSU-23-20</caseId><link>http://icoregon.technologypublisher.com/technology/54308</link><description><![CDATA[The nanofibers are loaded with a pair of growth factors that promote efficient wound healing through sustained activation of select pathways 

Background   
An average of 2% of the total United States population have chronic wounds, but current treatments are inadequate. We&rsquo;re developing new ways to heal chronic wounds by using electrospun nanofibers loaded with specific growth factors. Electrospun nanofibers structurally and functionally resemble extracellular matrix, and when loaded with wound healing factors, are a promising form of wound dressing to promote better healing. 

Technolo...]]></description><pubDate>Thu, 30 May 2024 16:21:47 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/54308</guid></item><item><title>Inhibitors of cancer-mediated bone destruction</title><caseId>2670</caseId><link>http://icoregon.technologypublisher.com/technology/54228</link><description><![CDATA[Summary
Current drugs for bone metastases merely prevent and slow the breakdown of bone, but are ineffective in slowing the spread of cancer. The current technology is a dual-acting bone defender (DABD), which acts to prevent bone destruction while simultaneously attacking cancer&rsquo;s ability to spread.

Technology Overview
In many cancers, especially prostate, breast and lung, a primary site of metastasis is bone.&nbsp; Approximately 280,000 adults in US currently have metastatic bone disease and each year an additional 323,000 cancers at high-risk for bone metastasis are diagnosed. This c...]]></description><pubDate>Mon, 20 May 2024 15:14:24 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/54228</guid></item><item><title>Sunscreen Compounds and Formulations</title><caseId>OSU-23-51</caseId><link>http://icoregon.technologypublisher.com/technology/53422</link><description>Meadowfoam derived sunscreen compounds that reduce UVB-induced DNA damage 

Background   
Chronic skin exposure to solar ultraviolet radiation (UVR) leads to accumulated DNA damage resulting in skin aging and the possibility of cancer. To prevent this, sunscreens are formulated with additives that reflect or absorb UV wavelengths that are incident on the skin (i.e., UVA and UVB). While commercially available sunscreen formulations effectively prevent the deleterious effects of UVR, there have been some recent concerns related to safety and environmental toxicity for marine organisms. New sunsc...</description><pubDate>Fri, 23 Feb 2024 16:47:24 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/53422</guid></item><item><title>eDentin- a tissue engineered reparative dentin</title><caseId>3192</caseId><link>http://icoregon.technologypublisher.com/technology/53350</link><description><![CDATA[Summary

Current dental restoration materials trigger immune responses and poorly replicate the natural structure of the tooth, which delays the healing process.&nbsp; The current technology is a novel biomaterial that more closely mimics natural dentin and thereby allows for more efficient healing of the tooth.

Technology Overview

Cement-based materials are the current gold standard used for reparative dental procedures where damage to the internal dentin has occurred.&nbsp; However, these materials lack the complexity and functionality of dentin, trigger large immune responses, and result ...]]></description><pubDate>Thu, 15 Feb 2024 09:07:44 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/53350</guid></item><item><title>Artificial Intelligence-Assisted Projection-Resolved Optical Coherence Tomographic Angiography (aiPR-OCTA)</title><caseId>3193</caseId><link>http://icoregon.technologypublisher.com/technology/53211</link><description><![CDATA[Summary

The current artificial intelligence algorithm removes projection artifacts in optical coherence tomographic angiography images and improves the signal-to-noise ratio.

Technology Overview

A major limitation of optical coherence tomography angiography (OCTA) are image artifacts, particularly projection artifacts, which make the detection of flow changes difficult to localize. 

Researchers from OHSU&rsquo;s Casey Eye Institute have developed the first artificial intelligence algorithm to remove OCTA projection artifacts. The AI algorithm consists of a combined convolutional neural net...]]></description><pubDate>Fri, 02 Feb 2024 07:43:49 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/53211</guid></item><item><title>A microcontroller for easier whole-cell patch clamping on dendrites and axons</title><caseId>3127</caseId><link>http://icoregon.technologypublisher.com/technology/53066</link><description><![CDATA[Summary

The current technology is a microcontroller that allows for the application of controlled negative pressure and simultaneous electrical impulses to make it easier to obtain whole-cell patch clamp recordings on small cellular structures. 

Technology Overview

Whole-cell patch clamping is a technique commonly employed to study the electrical properties of neurons and other biological cells. However, the methodology requires extensive training and can be difficult for new students and technicians to learn.&nbsp; This is especially true for clamping onto small structures such as dendrite...]]></description><pubDate>Tue, 16 Jan 2024 06:57:35 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/53066</guid></item><item><title>Covalent inhibitors of PARP-16 for cancer treatment</title><caseId>3015</caseId><link>http://icoregon.technologypublisher.com/technology/53027</link><description><![CDATA[Summary
The current technology is a selective, covalent inhibitor of PARP16 with potential therapeutic applications for the treatment of cancer. 

Technology Overview
The poly-ADP-ribose-polymerase (PARP) family is made up of 17 enzymes in humans that are increasingly recognized as major downstream regulators of NAD+-mediated signaling in cells.&nbsp; PARP1 inhibitors have shown efficacy as cancer drugs, raising interest in understanding the therapeutic potential for other PARP family members. 

Recent studies demonstrate that PARP16 is essential for the survival of several cancers, including ...]]></description><pubDate>Fri, 05 Jan 2024 13:04:12 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/53027</guid></item><item><title>An OCT method to improve scleral lens fitting</title><caseId>3133</caseId><link>http://icoregon.technologypublisher.com/technology/53022</link><description><![CDATA[Summary
The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting.

Technology Overview
Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition area between the cornea and the sclera (see Figure). &nbsp;Currently, patients must go through a process of trial and error to have scleral lenses fitted, which is inefficient and highly dependent on a practitioner&rsquo;s experience.&nbsp; ...]]></description><pubDate>Fri, 05 Jan 2024 10:20:52 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/53022</guid></item><item><title>CD74 as a biomarker and therapeutic target for familial platelet (FPD) disorder</title><caseId>3286</caseId><link>http://icoregon.technologypublisher.com/technology/53009</link><description><![CDATA[Summary
Research at OHSU has identified the CD74 signaling cascade as a potential therapeutic target and diagnostic biomarker for RUNX1-mutated familial platelet disorder (FPD), which is a premalignant condition for acute myeloid leukemia.&nbsp; 

Technology Overview
Current estimates suggest as many as 18,000 people may be living with RUNX1-FPD in the United States, and these patients are at an increased risk for the development of blood and bone marrow cancers. Roughly 35-40% of FPD patients go on to develop acute myeloid leukemia at an average age of 33 years. &nbsp;As such, diagnosis of FP...]]></description><pubDate>Wed, 03 Jan 2024 09:55:08 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/53009</guid></item><item><title>Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin</title><caseId>OSU-06-38</caseId><link>http://icoregon.technologypublisher.com/technology/52895</link><description>Background   
The emerging and persistent threat of multidrug-resistant bacterial infections has resulted in enormous healthcare costs and poses major challenges to public health. To address the need for new antibiotics capable of combating the gowning problem of resistance, Oregon State University researchers cloned and patented the biosynthetic gene cluster for Enramycin, which is a peptide antibiotic produced in S. fungicidicus and widely used as a feed additive for pigs and chickens, and also developed methods for generating a library of enramycin analogs. 

Technology Description    
To p...</description><pubDate>Thu, 07 Dec 2023 13:16:27 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52895</guid></item><item><title>Metamaterial Micro-LED Device</title><caseId>OSU-22-48</caseId><link>http://icoregon.technologypublisher.com/technology/52786</link><description>This LED uses a hybrid nanostructure to improve efficiency and intensity while avoiding costly transfer processes 

Background   
Recently, colloidal quantum dots (QDs) have appeared as promising emissive materials for micro-LEDs that can be used to form display panels without complicated transfer processes. Despite the remarkable luminescence properties of QDs, LEDs based solely on photoluminescence and/or electroluminescence inefficiently convert light excitation or injected current to radiative emissions. Also, a limited percentage of the generated photons can escape the device to the free ...</description><pubDate>Tue, 14 Nov 2023 16:51:54 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52786</guid></item><item><title>Workplace Mental Health Support Training for Leaders - individual training seats</title><caseId>3191-A</caseId><link>http://icoregon.technologypublisher.com/technology/52772</link><description>Summary

The Workplace Mental Health Support Training for Leaders is a 1-hour online training designed by occupational health psychology scientists and has been scientifically demonstrated to provide valuable training for company leaders and improve employee feelings of wellness. 

Technology Overview

Burnout, mental distress, and mental illnesses like depression and anxiety are at an all-time high in the wake of COVID-19. According to the National Safety Council, employers spend approximately $15,000 annually per employee who is experiencing mental distress, due to lost days and increased em...</description><pubDate>Mon, 13 Nov 2023 11:38:22 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/52772</guid></item><item><title>Postprocessing algorithms to minimize fixed pattern artifact and reduce trigger jitter in swept source OCT</title><caseId>2057</caseId><link>http://icoregon.technologypublisher.com/technology/52482</link><description><![CDATA[
Summary

OHSU developed post-processing algorithms which could minimize fixed pattern artifact and reduce trigger jitter in swept source optical coherence tomography (SS-OCT).

Technology Overview

Swept-source OCT has advantages of less fringe washout and faster imaging speeds compared to conventional spectraldomain detection.&nbsp; Therefore, it is attractive for both structural and Doppler OCT imaging. Unfortunately, in some SS-OCT systems, there is uncertainty in trigger timing so that the starting point of the spectral interferogram acquisition changes from cycle to cycle in wavenumber (...]]></description><pubDate>Wed, 27 Sep 2023 07:23:57 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/52482</guid></item><item><title>COVID-19 vaccination training video</title><caseId>2982</caseId><link>http://icoregon.technologypublisher.com/technology/52481</link><description><![CDATA[
Technology Overview

This training video provides comprehensive training on COVID-19 vaccinations and key aspects of a COVID-19 mass immunization program.&nbsp; It is a one-stop shop resource to train participants to be able to provide safe and effective COVID-19 vaccinations.&nbsp; This training is being used by 58 counties in California through the State of California Emergency Medical Services Authority.

This video was used to train OHSU vaccinators, including Day 2 nursing students.&nbsp; We carried out 27,000 shots in a little over one month.

This COVID-19 Vaccination Training Video, a...]]></description><pubDate>Wed, 27 Sep 2023 07:17:10 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/52481</guid></item><item><title>Retinomorphic Sensors</title><caseId>OSU-20-48</caseId><link>http://icoregon.technologypublisher.com/technology/52429</link><description>This sensor, intended for use in computer vision applications, only produces a signal in response to changes in light conditions. 

Background   
Inspired by the way retinal cells respond to light, retinomorphic sensors are hoped to enable faster identification of moving objects than software-based approaches. Unlike conventional optical sensors, such as photodiodes, retinomorphic sensors are designed to produce an output signal in response to changes in illumination, but not under constant illumination. Currently, the analysis of visual information occurs almost exclusively in processors, wit...</description><pubDate>Thu, 14 Sep 2023 14:36:16 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52429</guid></item><item><title>Aluminum Oxide Thin Films from Aqueous Precursors</title><caseId>OSU-10-30</caseId><link>http://icoregon.technologypublisher.com/technology/52358</link><description>A patented aqueous synthesis route for making high quality alumina thin films of exceptional quality and smoothness 

Background   
Aluminum oxide has many desirable properties making it technologically important as a barrier coating, optical film, and as a dieletric thin-film component of electronic devices. The quality of the material varies with precursor quality and deposition method. Variations in quality can have a profound impact on commercial and industrial applications. Conventional approaches for the formation of aluminum oxide thin films include, for example, chemical vapor depositi...</description><pubDate>Thu, 31 Aug 2023 17:35:06 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52358</guid></item><item><title>Engine Modification for Onboard NG Compression and Refueling</title><caseId>OSU-14-15</caseId><link>http://icoregon.technologypublisher.com/technology/52282</link><description>A dual mode engine cylinder that allows a single engine to both operate from and compress natural gas for onboard refueling 

Background   
Reciprocating internal combustion engines for passenger and commercial vehicles that are configured to operate on natural gas are commonly available. Internal combustion engines configured to operate using conventional motor fuels, such as gasoline or diesel, are also easily converted to run on natural gas. However, relatively few refueling stations exist that offer compressed natural gas for use in passenger and commercial vehicles. As a result, operators...</description><pubDate>Sun, 13 Aug 2023 16:48:59 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52282</guid></item><item><title>Engine Modification for Onboard NG Compression and Refueling</title><caseId>OSU-13-09</caseId><link>http://icoregon.technologypublisher.com/technology/52281</link><description>A dual mode engine cylinder that allows a single engine to both operate from and compress natural gas for onboard refueling 

Background   
Reciprocating internal combustion engines for passenger and commercial vehicles that are configured to operate on natural gas are commonly available. Internal combustion engines configured to operate using conventional motor fuels, such as gasoline or diesel, are also easily converted to run on natural gas. However, relatively few refueling stations exist that offer compressed natural gas for use in passenger and commercial vehicles. As a result, operators...</description><pubDate>Sun, 13 Aug 2023 16:43:46 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52281</guid></item><item><title>Cobalt and Nickel FREE Cathodes for Li-Ion Batteries</title><caseId>OSU-22-16</caseId><link>http://icoregon.technologypublisher.com/technology/52278</link><description>A composite copper sulfide - alkali metal salt cathode composition for high efficiency, high density alkali metal batteries

Background 
High energy rechargeable batteries are in ever-increasing demand to power consumer electronics and electric vehicles. Although lithium-ion batteries (LIBs) have been successfully used for portable electronics in the past three decades and more recently for electric vehicles, they are facing a challenging bottleneck regarding high cost and the lack of sustainability. The conventional cathodes of LIBs that operate on topotactic insertion reactions such as lithi...</description><pubDate>Fri, 11 Aug 2023 14:45:27 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52278</guid></item><item><title>Electrocatalytic Polymer Biosensor</title><caseId>OSU-22-15</caseId><link>http://icoregon.technologypublisher.com/technology/52277</link><description>An extremely sensitive, stable, and specific biosensor using electrocatalytic molecularly imprinted polymers and no enzymes or reagents

Background 
Electrochemical biosensors can successfully detect and quantify diverse biological samples including macromolecules, whole viruses, and cells. Due to their fabrication methods electrochemical biosensors can be mass produced inexpensively. However, many electrochemical biosensors do not have a specific binding mechanism resulting in non-specific binding of analytes. To overcome this issue, the general solution has been to coat electrode surfaces in...</description><pubDate>Fri, 11 Aug 2023 11:38:49 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/52277</guid></item><item><title>Multimeric Therapeutic Nanobodies</title><caseId>OSU-21-51</caseId><link>http://icoregon.technologypublisher.com/technology/51796</link><description><![CDATA[Background   
Assembling nanobodies (Nb) into polyvalent multimers is a powerful strategy for improving the effectiveness of Nb-based therapeutics and biotechnological tools. However, generally effective approaches to Nb assembly are currently restricted to the N- or C-termini, greatly limiting the diversity of Nb multimers that can be produced. 

Here, Oregon State University researchers show that reactive tetrazine groups &ndash; site-specifically inserted by genetic code expansion (GCE) at Nb surface sites &ndash; are compatible with Nb folding and function. 

This tetrazine-based approach ...]]></description><pubDate>Mon, 31 Jul 2023 09:29:35 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/51796</guid></item><item><title>Nanoparticle ultrasound contrast agents with high acoustic activity</title><caseId>2823</caseId><link>http://icoregon.technologypublisher.com/technology/51359</link><description><![CDATA[
Summary

Contrast-enhanced ultrasound allows for low-cost minimally-invasive imaging; however, the size of typical contrast reagents prevents them from penetrating tumors thereby limiting their utility for cancer diagnostic and therapeutic purposes (theranostics). Oregon Health &amp; Science University (OHSU) researchers have developed novel nanoparticle contrast agents that can be prepared at large scale, utilized at low concentrations and used in both research and clinical applications with standard ultrasound equipment. 

Technology Overview

Contrast-enhanced is a cost-effective imaging t...]]></description><pubDate>Thu, 15 Jun 2023 07:04:51 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/51359</guid></item><item><title>Meal detection and size estimation for artificial pancreas devices using machine learning</title><caseId>3112</caseId><link>http://icoregon.technologypublisher.com/technology/51325</link><description><![CDATA[&shy;Summary
The current technology can be used within an automated insulin delivery system to automate insulin delivery (AID) in response to meals. This technology has the potential to reduce the burden of a person living with type 1 diabetes using an AID and potentially improving glucose management by accurately and automatically delivering insulin in response to detected meals. 

Technology Overview
Closed-loop systems, also known as artificial pancreas devices, for automated insulin delivery (AID) facilitate diabetes management, but still require patients to manually enter meals and estima...]]></description><pubDate>Thu, 08 Jun 2023 07:39:47 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/51325</guid></item><item><title>Rapid antibody conjugation technique</title><caseId>3194</caseId><link>http://icoregon.technologypublisher.com/technology/51110</link><description><![CDATA[&shy;Summary
The current technology is an improved method of antibody conjugation that allows for rapid and scalable antibody labeling, which could be utilized for a number of omics techniques and other antibody-based platforms.

Technology Overview
In order to label and functionalize antibodies, direct or secondary conjugations are typically employed. Current approaches of antibody conjugation, including the use of antibody targeting proteins, have been instrumental in accelerating multi-omics analyses by enabling a large array of biological targets to be labeled and subsequently identified o...]]></description><pubDate>Wed, 17 May 2023 12:42:52 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/51110</guid></item><item><title>De novo peptide sequencer</title><caseId>3108</caseId><link>http://icoregon.technologypublisher.com/technology/51106</link><description>Summary
De novo protein-sequencing approaches are poised to revolutionize nearly all fields of biological research and medicine; however current approaches are low-throughput and limited in their sensitivity. The current technology is a novel method that could be implemented with existing reagents and equipment to improve de novo peptide sequencing capabilities. 

Technology Overview
Currently, untargeted proteomics primarily relies on digesting intact proteins into small peptides and reading their sequence using liquid chromatography-mass spectroscopy (LC-MS). However, LC-MS and other current...</description><pubDate>Wed, 17 May 2023 12:29:35 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/51106</guid></item><item><title>Novel single-gene biomarker for acute myeloid leukemia prognosis</title><caseId>3081</caseId><link>http://icoregon.technologypublisher.com/technology/50878</link><description>Summary
The current technology is a novel set of biomarkers derived from the largest ever genomic and transcriptomic data set for acute myeloid leukemia (AML), which includes a novel single gene biomarker capable of strongly predicting AML prognosis.

Technology Overview
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with an incidence of over 20,000 cases per year in the US. Complex genetic and biological features of AML contribute to frequent drug resistance and disease relapse, with only a small percentage of patients achieving durable remission.

Using a dataset contai...</description><pubDate>Thu, 20 Apr 2023 10:07:41 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50878</guid></item><item><title>A method of enhancing cancer immunotherapies through androgen receptor modulation</title><caseId>3063</caseId><link>http://icoregon.technologypublisher.com/technology/50778</link><description><![CDATA[&shy;Summary
The current technology has the potential to enhance the effectiveness of checkpoint blockade for advanced prostate cancer patients by directly enhancing T cell function through a reduction in intrinsic androgen receptor signaling. 

Technology Overview
In many patients with advanced cancer, immunotherapy treatments have largely failed. Mechanisms of immunotherapy resistance are varied and represent tumor cell intrinsic mechanisms of treatment escape as well as tumor microenvironment mechanisms of resistance. Hormones such as androgens, represent one possible mechanism of immunothe...]]></description><pubDate>Wed, 05 Apr 2023 08:13:21 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50778</guid></item><item><title>Improved detection of heart-rate variability for wearable devices</title><caseId>2937</caseId><link>http://icoregon.technologypublisher.com/technology/50689</link><description><![CDATA[
Summary

Heart-rate variability (HRV) is a suggested marker of the autonomic nervous system, but artifacts produced by movement with wrist worn devices decreases the validity and utility of this data. Oregon Health &amp; Science University researchers have developed an improved method of removing motion artifacts, understanding the amount of data that can be removed without affecting the accuracy of the HRV specific metrics, and accurately measuring HRV from wearable devices for better monitoring in outpatient care and clinical trials. This technology can be used for medical technology, clini...]]></description><pubDate>Fri, 24 Mar 2023 09:51:50 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50689</guid></item><item><title>Anoxic/hypoxic brain imaging map</title><caseId>2745</caseId><link>http://icoregon.technologypublisher.com/technology/50633</link><description>Summary
Brain damage in newborns arises as a consequence of oxygen shortage in the brain. This injury is often difficult to diagnose in young children due to intrinsic differences between the developing and adult brain. Scientists at OHSU have developed a highly-accurate diagnostic analysis to localize brain injuries in developing as well as adult brains. 

Technology Overview
One of the leading causes of infant brain damage is the lack of oxygen shortly after birth, called anoxia (prolonged lack of oxygen) or hypoxia (decrease in oxygen levels). Traditional imaging methods often fail to captu...</description><pubDate>Thu, 16 Mar 2023 07:28:58 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50633</guid></item><item><title>Effective combinations of targeted agents for hematologic malignancies</title><caseId>2349</caseId><link>http://icoregon.technologypublisher.com/technology/50632</link><description><![CDATA[Summary
Current treatment strategies for acute myeloid leukemia (AML) have low efficacy rates, due in part to the complex and heterogenous underlying genetics of this cancer. Oregon Health &amp; Science University researchers have developed a precision medicine approach for the treatment of AML by identifying an effective combination therapy for a specific genetic subpopulation of patients, potentially providing a means for more effective treatment of AML.

Technology Overview
Precision medicine relies on the ability to align medical interventions with individual patients at the time of diagno...]]></description><pubDate>Thu, 16 Mar 2023 07:15:41 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50632</guid></item><item><title>DailyDose decision support smart phone app to improve glycemic control in type 1 diabetes (T1D)</title><caseId>2936</caseId><link>http://icoregon.technologypublisher.com/technology/50297</link><description><![CDATA[Summary
A smart phone application and graphical user interface, which provides real-time dosing advice and weekly insulin dose adjustments to improve glucose management in patients with type 1 diabetes using daily insulin injections. 

Technology Overview
Close to 1.5 million people in the US have type 1 diabetes and many have difficulty managing their glucose effectively, particularly those without access to automated insulin pumps.&nbsp; These patients must attempt to accurately dose themselves multiple times a day with insulin injections to achieve stable glucose levels.&nbsp; Factors such ...]]></description><pubDate>Fri, 03 Feb 2023 10:58:27 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50297</guid></item><item><title>Metabolic activity diffusion imaging (MADI): dye-free, high-resolution MRI metabolic imaging</title><caseId>2346</caseId><link>http://icoregon.technologypublisher.com/technology/50296</link><description><![CDATA[Summary

The current technology is a contrast agent-free method of metabolic imaging based on detection of Na/K ATPase activity with MRI, that provides significantly higher resolution than current approaches such as PET. &nbsp;

Technology Overview 

Measuring metabolic activity in vivo can facilitate diagnoses of disease states and therapeutic responses. &nbsp;Existing imaging modalities for detecting metabolic activity, such PET and MRSI, require administration of&nbsp; exogeneous contrast agents and have lower spatial resolution than desired.&nbsp; To overcome these limitations, Oregon Heal...]]></description><pubDate>Fri, 03 Feb 2023 10:54:28 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50296</guid></item><item><title>Monoclonal antibodies for detection of viral capsids and gene therapy research</title><caseId>2808-A</caseId><link>http://icoregon.technologypublisher.com/technology/50242</link><description><![CDATA[&shy;Summary
The current technology is a series of monoclonal antibodies against AAVAnc80 capsids for gene therapy research.

Technology Overview
Detection and neutralization of viral capsids are needed to advance gene therapy research, but to date, no antibodies exist that can exclusively detect fully assembled AAVAnc80 capsids and not other serotype capsids.&nbsp; &nbsp;&nbsp;OHSU researchers have developed a set of novel monoclonal antibodies against AAVAnc80 capsids, including:


	Antibodies that recognize the fully-assembled AAVAnc80 capsids.
	Antibodies that recognize both fully-assemble...]]></description><pubDate>Wed, 01 Feb 2023 06:54:25 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50242</guid></item><item><title>Label-free fluorescent sensing of protease activity</title><caseId>2985</caseId><link>http://icoregon.technologypublisher.com/technology/50143</link><description><![CDATA[&shy;Summary
The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. 

Technology Overview
Dysregulated proteolytic activity is linked to many human diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Currently designed protease activity probes often suffer from high background signal due to the incomplete quenching of the dyes. The current technology offers a new type of prot...]]></description><pubDate>Wed, 18 Jan 2023 07:25:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/50143</guid></item><item><title>Improved removal of projection artifacts in optical coherence tomographic angiography</title><caseId>3142</caseId><link>http://icoregon.technologypublisher.com/technology/48922</link><description><![CDATA[&shy;Summary
The current algorithm improves projection artifacts removal for more accurate optical coherence tomographic angiography (OCTA) scans and better quantitative detection and monitoring of vascular abnormalities.

Technology Overview
Projection artifacts are one of the significant limitations of OCTA imaging, and a reliable projection-resolved OCTA algorithm is essential for accurate measurements of vascular abnormalities, such as macular ischemia and choroidal neovascularization (CNV). However, current solutions require time-intensive segmentation steps and still have limitations in ...]]></description><pubDate>Tue, 06 Dec 2022 08:20:28 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48922</guid></item><item><title>Spatially-resolved transcriptomics with enhanced capture and versatility</title><caseId>3048</caseId><link>http://icoregon.technologypublisher.com/technology/48920</link><description>Summary
An improved platform for spatial transcriptomics, which could be mass produced and would allow for overall increased detection of transcripts, including for lower-expressed sequences. 

Technology Overview
Spatial transcriptomics allows for the measurement of gene activity within a sample while mapping where that activity is occurring; however, current methods are limited in the number of probes that can fit onto the 2D sampling surface (i.e. slide). 

OHSU researchers have developed an improved platform that allows for an increased number of probes and thus captured sequences. Feature...</description><pubDate>Tue, 06 Dec 2022 06:46:47 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48920</guid></item><item><title>High-throughput precision medicine screening for solid tumors</title><caseId>2584</caseId><link>http://icoregon.technologypublisher.com/technology/48899</link><description>Summary
The current technology provides a unique ex vivo biopsy culture method for improved and personalized screening of multiple drug combinations for solid tumors. 

Technology Overview
Precision medicine allows for cancer therapies to be tailored to individual tumor characteristics, but current screening methods often lack the capacity to 1) capture the full tumor microenvironment and/or 2) allow for the testing of multiple drugs and drug combinations. The current technology provides a novel method for precision medicine screening of solid tumors to better predict effective tumor therapies...</description><pubDate>Fri, 02 Dec 2022 09:06:56 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48899</guid></item><item><title>Software for deep learning-based inference of biomarker distribution in cancer samples</title><caseId>2630</caseId><link>http://icoregon.technologypublisher.com/technology/48898</link><description><![CDATA[Summary
Multiplexed tissue imaging (MTI) &nbsp;is a powerful tool for cancer pathology, but it is also expensive, which has limited its availability for underserved communities, particularly in the developing world. The current software uses hematoxylin &amp; eosin (H&amp;E) staining, which is more widely available, to predict oncology biomarker distribution, thereby making sophisticated pathology analysis cheaper and easier to perform. 

Technology Overview
Multiplexed Tissue Imaging (MTI) Immunofluorescent (IF) imaging is a powerful method of measuring the spatial distribution of critically-...]]></description><pubDate>Fri, 02 Dec 2022 08:26:39 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48898</guid></item><item><title>Improved Thin Film</title><caseId>OSU-18-67</caseId><link>http://icoregon.technologypublisher.com/technology/48875</link><description>Background   
Thin film deposition of metal oxide materials from aqueous solution is challenged by the solubility and gelling behavior of precursors. For example, some metal cations are poorly soluble at neutral pH, but added acid or base is detrimental to substrate stability and film adherence. In addition, soluble salts of metal cations tend to crystallize rather than gel, leading to poor film morphology without adherence or conformal coverage. An intriguing alternative to water-sensitive alkoxide precursors for spin coating of metal oxide thin films is metal-oxo clusters. 

Technology Descr...</description><pubDate>Mon, 28 Nov 2022 12:12:18 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/48875</guid></item><item><title>Framework for 3D retinal pathology detection by OCT/OCT-angiography</title><caseId>3088</caseId><link>http://icoregon.technologypublisher.com/technology/48620</link><description>​​Summary
The current technology provides a platform for a fully-automated OCT-based 3D detection of retinal pathologies with significantly reduced processing requirements, which could allow for more wide-spread adoption of OCT/OCT-angiography 3D analysis. 

Technology Overview
Optical coherence tomography (OCT) and its angiography can be used to provide more accurate analysis of retinal pathologies in 3D; however, it can be prohibitively time-consuming and remains under-utilized. The current technology is a framework for structural and angiographic OCT 3D image analysis developed by leaders i...</description><pubDate>Fri, 14 Oct 2022 14:41:19 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48620</guid></item><item><title>Fully-automated diabetic retinopathy (DR) screening based on OCT and its angiography</title><caseId>3105</caseId><link>http://icoregon.technologypublisher.com/technology/48619</link><description><![CDATA[Summary
The current technology provides a framework for a fully-automated deep-learning-based diabetic retinopathy screening that relies solely on optical coherence tomography (OCT) and its angiography, without the need for fundus photography or time-intensive clinical evaluation.

Technology Overview
Diabetic retinopathy (DR) is a leading cause of preventable blindness globally but current diagnosis methods rely on fundus photography, which has low sensitivity and specificity.&nbsp; Optical coherence tomography (OCT) offers improved sensitivity and has been used to supplement fundus photograp...]]></description><pubDate>Fri, 14 Oct 2022 14:08:10 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48619</guid></item><item><title>Nocturnal hypoglycemia prediction algorithm</title><caseId>2708</caseId><link>http://icoregon.technologypublisher.com/technology/48554</link><description>Summary
This hypoglycemia prediction algorithm calculates the risk of possible hypoglycemic episodes before the patient goes to bed.

Technology Overview
Utilizing a support regression algorithm (SVR) to predict minimum glucose levels and a decision theory/cost-benefit analysis to estimate nocturnal glucose alert levels, this algorithm predicts nighttime hypoglycemia before the patients goes to sleep. By using this algorithm, type 1 diabetes patients can minimize the risk of overnight hypoglycemic episodes as it can predict and notify patients to consume proper amounts of carbohydrates before ...</description><pubDate>Mon, 03 Oct 2022 15:18:37 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48554</guid></item><item><title>Non-surgical permanent female contraception using a novel transcervical delivery device</title><caseId>2919</caseId><link>http://icoregon.technologypublisher.com/technology/48489</link><description><![CDATA[Summary
This catheter device is designed to provide clinicians with a simple, inexpensive office-based procedure for the assessment of tubal patency or delivery of a permanent contraceptive agent to the fallopian tubes.

Technology Overview
Currently, all methods of female permanent contraception require invasive surgery. This limits access to have the procedure, particularly in low-resource areas without adequate surgical facilities.&nbsp; Thus, an unmet need for less-invasive approaches to permanent contraceptives for women looking for long-term pregnancy prevention exists worldwide. &nbsp;&...]]></description><pubDate>Mon, 19 Sep 2022 07:40:23 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48489</guid></item><item><title>Photoactivatable modulation of antibody binding</title><caseId>2939</caseId><link>http://icoregon.technologypublisher.com/technology/48080</link><description><![CDATA[&shy;Summary
The current technology involves a blocking construct that has the potential to increase antibody specificity and reduce unwanted off-target effects by modulating antibody activation in a manner that is predictable, reproducible and does not require genetic modification of the antibody sequence. 

Technology Overview
Traditional antibodies cannot be temporally or spatially controlled, which can lead to unwanted side effects in therapeutic applications such as cancer immunotherapy, where both heathy and cancerous cells are targeted. 

Oregon Health &amp; Science University researche...]]></description><pubDate>Tue, 16 Aug 2022 15:52:52 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48080</guid></item><item><title>Universal nanoprobes for imaging and treatment of cancer</title><caseId>3024</caseId><link>http://icoregon.technologypublisher.com/technology/48076</link><description><![CDATA[Summary
Medical imaging is currently incapable of detecting very small tumors and there is a need for new contrast agents that allow for earlier detection of cancers.&nbsp; The current technology is a self-assembled nanoprobe that specifically accumulates in a broad range of solid tumors to enable 1) high-resolution imaging for earlier cancer detection and 2) targeted drug delivery for cancer chemotherapy with less side-effects. 

Technology Overview
Medical imaging methods have multiple applications in cancer detection and management, including detection of solid malignancies, monitoring ther...]]></description><pubDate>Tue, 16 Aug 2022 13:57:07 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/48076</guid></item><item><title>Molecular Probe and Sensor for Detecting Cu2+</title><caseId>OSU-20-72</caseId><link>http://icoregon.technologypublisher.com/technology/47934</link><description>Background    
The detection of trace quantities of copper in environmental and biological samples is in high demand. Numerous analytical techniques are available to detect trace quantities of Cu2+, including atomic absorption spectrometry, inductively coupled plasma mass spectrometry, flame photometry, gravimetric detection, chromatography, fluorometry, and electrochemistry. Limitations of these techniques include sample pretreatment, use of complicated, bulky, and expensive instruments, and sophisticated procedures. These limitations are time-consuming and a challenge for the routine analysi...</description><pubDate>Thu, 04 Aug 2022 03:05:14 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/47934</guid></item><item><title>Magneto-Acoustic Signal Correlator</title><caseId>OSU-22-05</caseId><link>http://icoregon.technologypublisher.com/technology/47933</link><description>By harnessing coupling between magnetic and acoustic domains, this device is efficient for signal processing well into the mm-wave range 

Background   
Current acoustic transducers, filters, sensors, and communication systems face issues related to efficiency, frequency selectivity, tunability, and miniaturization. For example, acoustic wave filters are useable only up to about 6 GHz, beyond which excessive acoustic losses and dimensional scaling limits make acoustic devices ineffective. Further, some transducers may exhibit limited conversion efficiency or frequency response, and existing fi...</description><pubDate>Thu, 04 Aug 2022 02:33:53 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/47933</guid></item><item><title>A Device for Measuring Orbital States of Electrons</title><caseId>UO-16-22</caseId><link>http://icoregon.technologypublisher.com/technology/47151</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on a device for measuring orbital states of electrons, specifically their orbital angular momentum (OAM). This device uses spatially varying electric fields around needle electrodes to measure the quantized angular momentum of charged particles. The technology is currently in the development stage, with promising cross-industry applications in electron microscopy, spectroscopy, and laboratory systems.&nbsp;

2. Key Features and Benefits&nbsp;


	
	New Field of Electron Spectroscopy:&nbsp;Opens up&nbsp;new possibilities for measuring orbital a...]]></description><pubDate>Fri, 10 Jun 2022 22:42:24 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47151</guid></item><item><title>AB Zebrafish Line</title><caseId>UO-11-28</caseId><link>http://icoregon.technologypublisher.com/technology/47150</link><description>The AB line is derived from two lines, A and B, purchased by George Streisinger at different times from a pet shop in Albany, Oregon. The original A and B lines probably originated from a hatchery in Florida. Haploid offspring from individual females of the AB line were screened for healthy, good looking embryos, and those females were used to make future generations by crossing them to unselected males. The AB line was maintained in this manner by the Oregon labs from the 1970s to the 1990s. This procedure reduced the number of lethal mutations so that this line can be used for parthenogenesi...</description><pubDate>Fri, 10 Jun 2022 22:07:52 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47150</guid></item><item><title>absolute Zebrafish Line</title><caseId>UO-12-06</caseId><link>http://icoregon.technologypublisher.com/technology/47149</link><description><![CDATA[The absolute&nbsp;zebrafish line is a cross between two recessive, non-lethal mutations: mitfab692(nacre) and ednrb1ab140 (rose). The result is a transparent zebrafish line that allows observation of organs, as well as fluorescent reporter gene products, without invasive manipulations. The double mutant lacks Melanophores (black pigment cells) and iridophores (silver/reflective pigment cells), but retains some Xanthophores (yellow pigment cells). Adults have yellowish/transparent skin. The double-mutant line is bred according to standard mendelian genetics. &nbsp;&nbsp;&nbsp;

Advantages: Norm...]]></description><pubDate>Fri, 10 Jun 2022 21:33:06 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47149</guid></item><item><title>Device and Method for Creating Gaussian Electron Beams</title><caseId>UO-13-07</caseId><link>http://icoregon.technologypublisher.com/technology/47148</link><description><![CDATA[University&nbsp;of Oregon Researchers: Benjamin McMorran

Patent: 9,240,255 issued 1/19/2016 (UO-13-07)

Device and Method for Creating Gaussian Electron Beams.

Technology Background/Definition of Problem:&nbsp; Electron beams used in instrumentation such as scanning electron microscopes, transmission electron microscopes, microprobes, etc. exhibit numerous deficiencies that limit the performance of these instruments. For example, electron beams are generally defined by apertures with hard edges, usually circular. Diffraction from these hard-edge apertures results in a beam profile known as a...]]></description><pubDate>Fri, 10 Jun 2022 17:24:11 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47148</guid></item><item><title>Maize Seeds with Mu Insertions</title><caseId>UO-12-17</caseId><link>http://icoregon.technologypublisher.com/technology/47147</link><description>High-copy transposons have been effectively exploited as mutagens in a variety of organisms. However, their utility for phenotype-driven forward genetics has been hampered by the difficulty of identifying the specific insertions responsible for phenotypes of interest. University of Oregon researchers have invented a new method that can substantially increase the throughput of linking a disrupted gene to a known phenotype in high-copy Mutator (Mu) transposon lines in maize. The approach uses the Illumina platform to obtain sequences flanking Mu elements in pooled, bar-coded DNA samples. Inserti...</description><pubDate>Fri, 10 Jun 2022 17:19:36 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47147</guid></item><item><title>All-Optical Multiplexer and De-multiplexer for Temporal Modes of Electromagnetic Radiation using Nonlinear Optical Cavities and Shaped Laser Pulses</title><caseId>UO-18-26</caseId><link>http://icoregon.technologypublisher.com/technology/47146</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on an all-optical multiplexer and de-multiplexer for temporal modes of electromagnetic radiation using nonlinear optical cavities and shaped laser pulses. This device selectively shifts the carrier frequency of temporal-mode components of electromagnetic pulses using nonlinear wave mixing in a microcavity system. The technology is currently in the development stage, with promising cross-industry applications in telecommunications, quantum computing, and integrated photonics.&nbsp;

2. Key Features and Benefits&nbsp;


	
	100% Selective Quantu...]]></description><pubDate>Fri, 10 Jun 2022 16:57:43 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47146</guid></item><item><title>Use of Ultraviolet and Aluminum Nanoclusters to Form Water Repellents for Textiles</title><caseId>UO-21-031</caseId><link>http://icoregon.technologypublisher.com/technology/47145</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces a novel&nbsp;methodology&nbsp;for creating water-repellent coatings on textiles using UV light and an aluminum precursor. This ultralow-temperature process forms aluminum oxide (Al2O3) coatings, offering a scalable and cost-effective solution for enhancing the durability and water resistance of textiles. The technology leverages solution processing methods, making it suitable for large-scale applications in textile manufacturing, outdoor apparel, automotive, and aerospace industries. Currently in the development stage, this technology hold...]]></description><pubDate>Fri, 10 Jun 2022 16:01:32 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47145</guid></item><item><title>Device and Method for Determining the Speed of Printing of a Fiber and the Length of a Printed Fiber</title><caseId>UO-22-010</caseId><link>http://icoregon.technologypublisher.com/technology/47144</link><description><![CDATA[Summary of the Technology: This innovation allows the control of the process of electrohydrodynamic (EHD) jet printing in which an ink is printed on a substrate as a continuous line or fiber, forming predesigned 2D patterns and 3D structures (a.k.a. &ldquo;near-field electrospinning&rdquo; NFES). The technology allows determination of the speed at which the EHD ink jet approaches the substrate before it collects transforming into a printed fiber. The knowledge of its speed of approach is critical for controlling the process of printing and create high-resolution patterns and structures, and, u...]]></description><pubDate>Fri, 10 Jun 2022 15:56:41 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47144</guid></item><item><title>Printing Device and Method</title><caseId>UO-22-009</caseId><link>http://icoregon.technologypublisher.com/technology/47143</link><description><![CDATA[Summary of the Technology: A versatile 3D printing technology is offered in which electrostatic control is used to form a continuous electrohydrodynamic ink jet and to precisely position it on a substrate forming a predefined pattern made of solid fiber with fiber diameter typically in the few-micron or submicron ranges. The technology uses electrostatic forces to deflect the trajectory of the&nbsp;fast-moving jet in its flight toward the substrate, in a time-varying fashion. This technology is capable of printing predefined 2D patterns and 3D microstructures with submicrometer resolution and ...]]></description><pubDate>Fri, 10 Jun 2022 15:55:06 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47143</guid></item><item><title>Phononic Quantum Networks of Solid-state Spins Using Phononic Crystal Waveguides for One-sided Coupling</title><caseId>UO-18-23</caseId><link>http://icoregon.technologypublisher.com/technology/47140</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on&nbsp;phononic&nbsp;quantum networks of solid-state spins using&nbsp;phononic&nbsp;crystal waveguides for one-sided coupling. This system aims to realize a quantum network of solid-state spins using mechanical resonators and&nbsp;phononic&nbsp;crystal waveguides, serving as a platform for developing large-scale spin-based quantum computers. The technology is currently in the development stage, with promising cross-industry applications in quantum computing, telecommunications, and nanotechnology.&nbsp;

2. Key Features and Benefits&nbsp;


...]]></description><pubDate>Fri, 10 Jun 2022 15:31:45 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47140</guid></item><item><title>Deterministic Quantum Emitter Formation in Hexagonal Boron Nitride via Controlled Edge Creation</title><caseId>UO-19-19</caseId><link>http://icoregon.technologypublisher.com/technology/47131</link><description><![CDATA[1. Technology Overview&nbsp;

The invention&nbsp;leverages&nbsp;a novel method for deterministic quantum emitter formation in hexagonal boron nitride (hBN) using focused ion beam (FIB) milling. This technique achieves a high yield of quantum emitters with exceptional stability and brightness, making it ideal for integration into hybrid&nbsp;optoelectromechanical&nbsp;devices. The technology is currently in the development stage, with promising cross-industry applications in quantum computing, communication, and photonics.&nbsp;

2. Key Features and Benefits&nbsp;


	
	High Yield: Achieves 94% ...]]></description><pubDate>Fri, 10 Jun 2022 14:49:18 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/47131</guid></item><item><title>Label-free microfluidic device for cancer liquid biopsy</title><caseId>2812</caseId><link>http://icoregon.technologypublisher.com/technology/47040</link><description><![CDATA[
Summary

Liquid biopsies offer a less invasive method of early cancer detection; however, circulating cancer cells are rare and difficult to detect.&nbsp; The current technology is a device that allows for sensitive, label-free enrichment of circulating neoplastic cells in order to facilitate the detection of cancer biomarkers from peripheral blood samples.

Technology Overview

Cancer diagnostics is a growing market, and the ability to provide liquid biopsies is an attractive alternative for doctors and patients wanting to avoid invasive procedures. Researchers at Oregon Health &amp; Science...]]></description><pubDate>Wed, 01 Jun 2022 08:41:19 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/47040</guid></item><item><title>Cell-free RNA biomarkers capable of distinguishing cancer from premalignant disease</title><caseId>2825</caseId><link>http://icoregon.technologypublisher.com/technology/46598</link><description><![CDATA[
Summary

Early cancer detection is critical for improving long-term patient survival and highlights a need for new sensitive and minimally-invasive early detection methods.&nbsp; The current technology includes novel sets of cell-free RNA biomarkers that can be used to potentially distinguish between malignant and pre-malignant forms of certain cancers using a standard blood collection for liquid biopsy applications. 

Technology Overview

Cancer is often diagnosed after cancerous cells have spread systemically, dramatically lowering long-term patient survival. New tools for early cancer dete...]]></description><pubDate>Mon, 09 May 2022 07:20:30 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/46598</guid></item><item><title>Bipolar Membrane Catalysis</title><caseId>UO-19-64</caseId><link>http://icoregon.technologypublisher.com/technology/46569</link><description><![CDATA[University of Oregon Researchers are Producing Hydrogen via Membrane Water Electrolysis Using&nbsp;Earth Abundant Catalysts for Alkaline Exchange Membrane Electrolysis

Catalyzing heterolytic water dissociation (WD), H2O&rarr;H++OH&minus;, is practically important for accelerating electrocatalytic reactions that consume water and for fabricating bipolar-membrane (BPM) devices that couple different pH environments into a single electrochemical process. Slow water dissociation kinetics have led to bipolar membranes with poor electrochemical performance unsuitable for energy conversion technologi...]]></description><pubDate>Wed, 04 May 2022 12:58:27 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46569</guid></item><item><title>High Voltage Redox Electrolytes for Enhanced Electrochemical Capacitor Performance and Reduced Self-Discharge</title><caseId>UO-14-45</caseId><link>http://icoregon.technologypublisher.com/technology/46568</link><description><![CDATA[
Supercapacitors and batteries are the two leading forms of electrochemical energy storage. Both have unique advantages and can be applied to various applications. Supercapacitors can be charged quickly resulting in very high power density and can cycle hundreds of thousands of times with lifetimes measured in decades. However, these devices suffer from low energy density meaning their charge doesn&rsquo;t last as long when compared to a battery. On the other hand, batteries can maintain a longer charge but have a lower power output and lose their ability to retain energy over a lifetime of se...]]></description><pubDate>Wed, 04 May 2022 12:55:45 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46568</guid></item><item><title>Biological H2S / COS Donation by Thiocarbamates</title><caseId>UO-16-20</caseId><link>http://icoregon.technologypublisher.com/technology/46551</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on biological hydrogen sulfide (H₂S) and carbonyl sulfide (COS) donation using thiocarbamates. These compounds release COS, which is then converted to H₂S by hydrolysis or metabolism by carbonic anhydrase. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Slow-Releasing H₂S Donors: Provides sustained release of H₂S in response to external stimuli.&nbsp;
	



	
	Modular Donation Platform: A...]]></description><pubDate>Mon, 02 May 2022 14:52:30 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46551</guid></item><item><title>Fluorinated CPPs</title><caseId>UO-17-13</caseId><link>http://icoregon.technologypublisher.com/technology/46550</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on fluorinated cycloparaphenylenes (CPPs), which assemble into uniform, 1.3 nm cylindrical channels through a combination of&nbsp;perfluoroarene-arene and aryl C-H/aryl C-F interactions. This results in a well-defined, solid-state porous material reminiscent of&nbsp;a carbon nanotube. The technology is currently in the development stage, with promising cross-industry applications in nanotechnology, materials science, and chemical synthesis.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Uniform Cylindrical Channels: Provides defined nanostruc...]]></description><pubDate>Mon, 02 May 2022 14:47:48 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46550</guid></item><item><title>Indenoindenodi(benzothiophene)s (IIDBT)</title><caseId>UO-19-14</caseId><link>http://icoregon.technologypublisher.com/technology/46549</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on the synthesis and characterization of&nbsp;indenoindenodi(benzothiophene) (IIDBT) derivatives, which&nbsp;possess&nbsp;unique electronic properties, including large singlet-triplet energy gaps and moderately strong diradical character. These molecules are stable and have potential applications in organic electronics and materials science. The technology is currently in the development stage, with promising cross-industry applications in organic electronics, sensors, and advanced materials.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Lar...]]></description><pubDate>Mon, 02 May 2022 14:41:24 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46549</guid></item><item><title>Fluorescent Halogen Bonding Arylethynyl Scaffolds For Anion Recognition</title><caseId>UO-18-41</caseId><link>http://icoregon.technologypublisher.com/technology/46548</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on fluorescent halogen bonding&nbsp;arylethynyl&nbsp;scaffolds for anion recognition. These scaffolds&nbsp;utilize&nbsp;neutral para-positioned electron withdrawing groups to polarize halogen bond donating groups within the&nbsp;arylethynyl&nbsp;structure, enabling reversible anion binding in solution with a spectroscopic response upon binding. The technology is currently in the development stage, with promising cross-industry applications in agricultural, biomedical, and environmental monitoring.&nbsp;

2. Key Features and Benefits&nbsp;


	...]]></description><pubDate>Mon, 02 May 2022 14:25:50 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46548</guid></item><item><title>Method for Detection for Hydrosulfide Anion (HS-) and Hydrogen Sulfide (H2S)</title><caseId>UO-16-18</caseId><link>http://icoregon.technologypublisher.com/technology/46547</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on a new method for detecting hydrosulfide anion (HS⁻) and hydrogen sulfide (H₂S) using reversible, supramolecular binding interactions. This method&nbsp;utilizes&nbsp;non-covalent interactions, specifically hydrogen bonds, to detect HS⁻/H₂S without altering the analyte concentration. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Reversible Detection: Preserves analyte concentration du...]]></description><pubDate>Mon, 02 May 2022 14:22:51 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46547</guid></item><item><title>Compounds for Thiol-Triggered COS and/or H2S Release and Methods of Making and Using the Same</title><caseId>UO-18-43</caseId><link>http://icoregon.technologypublisher.com/technology/46544</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on thiol-triggered sulfenyl thiocarbonates and sulfenyl thiocarbamates that release carbonyl sulfide (COS) and hydrogen sulfide (H₂S) in the presence of biologically relevant thiols. These compounds offer a concomitant fluorescence response, providing optical&nbsp;indication&nbsp;of COS and H₂S release. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery.&nbsp;

2. Key Features and Benefits&nbsp;


	
	Fluorescence Response: Provides optic...]]></description><pubDate>Fri, 29 Apr 2022 11:40:39 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46544</guid></item><item><title>Thionoesters that Release H2S upon Thiol Ligation</title><caseId>UO-18-03</caseId><link>http://icoregon.technologypublisher.com/technology/46543</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on synthesizing&nbsp;thionoesters&nbsp;that release hydrogen sulfide (H₂S) upon thiol ligation. These small molecules react with L-cysteine and other cysteine derivatives to release H₂S,&nbsp;terminating&nbsp;in the formation of N-benzoyl-L-cysteine. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery.&nbsp;

2. Key Features and Benefits&nbsp;


	
	H₂S Release: Provides optical&nbsp;indication&nbsp;of biological processes.&nbsp;
	



	
	T...]]></description><pubDate>Fri, 29 Apr 2022 11:37:33 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46543</guid></item><item><title>Conductive Polymers Containing Nanohoop Building Blocks</title><caseId>UO-20-001</caseId><link>http://icoregon.technologypublisher.com/technology/46541</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces conductive polymers&nbsp;containing&nbsp;nanohoop&nbsp;building blocks, offering a scalable and cost-effective solution for enhancing the electrical and mechanical properties of organic electronic devices. These&nbsp;nanohoops&nbsp;are attached to the polymers via alkyne bonds, ensuring their pi-bond system is conjugated to that of the polymers. The technology holds significant potential for applications in organic electronics, flexible displays, chemical sensors, and photovoltaic cells, providing improved performance and scalability. Curr...]]></description><pubDate>Fri, 29 Apr 2022 11:13:58 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/46541</guid></item><item><title>Device for sustained doppler telemetry</title><caseId>2951</caseId><link>http://icoregon.technologypublisher.com/technology/45926</link><description><![CDATA[
Summary

Doppler measurement of blood flow following vascular surgery is critical for safe patient monitoring, but this procedure can be time intensive.&nbsp; The current device would allow for the Doppler transducer to be fixed to the patient, allowing for continuous monitoring and thereby improving patient care and reducing hospital staff burden. 

Technology Overview

Following a vascular operation, it is standard practice to evaluate restored blood flow in the affected leg or extremity by Doppler.&nbsp; Current practice typically calls for periodic hourly Doppler assessments, which could ...]]></description><pubDate>Thu, 17 Feb 2022 07:02:25 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45926</guid></item><item><title>Software for automated identification and segmentation of perivascular spaces on MRI</title><caseId>2531</caseId><link>http://icoregon.technologypublisher.com/technology/45922</link><description><![CDATA[
Summary

Enlarged perivascular spaces (ePVS) in the brain are linked to several diseases, but detection at the resolution of clinical MRI relies on manual visual assessment, which are subjective, time-intensive and prone to error. The software automates ePVS detection in several commonly acquired MRI contrasts to increase efficiency and objectivity in quantifying whole brain ePVS burden in vivo. 

Technology Overview

Increased areas of enlarged perivascular spaces (ePVS) are associated with many prevalent diseases, including Alzheimer&rsquo;s disease, cerebral small vessel disease, cerebral ...]]></description><pubDate>Wed, 16 Feb 2022 06:58:20 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45922</guid></item><item><title>A Unified Strategy to Simplify and Enhance Studies of Protein Function</title><caseId>UO-19-72</caseId><link>http://icoregon.technologypublisher.com/technology/45851</link><description><![CDATA[Protein studies are universal across disciplines in biological sciences. Because of this ubiquity, numerous strategies exist to purify, localize, redirect, deplete, and visualize proteins in all model organisms. However, it can be cumbersome to create required strains to investigate the many different aspects of protein function. Even in yeast, one of the &ldquo;simplest&rdquo; model organisms, there is no streamlined approach that allows for robust protein localization and purification from a single strain. Instead, there are a host of unique N- and C-terminal tags that can be added for diffe...]]></description><pubDate>Mon, 31 Jan 2022 14:36:54 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/45851</guid></item><item><title>SpdE, a Novel Amino Acid-sensing Diguanylate Cyclase</title><caseId>UO-19-33</caseId><link>http://icoregon.technologypublisher.com/technology/45777</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces&nbsp;SpdE, a novel bacterial protein that senses specific amino acids (valine, proline, and isoleucine) at nanomolar concentrations. This&nbsp;highly sensitive&nbsp;protein offers significant potential for applications in clinical diagnostics, biotechnology, and industrial processes. The technology leverages&nbsp;established&nbsp;molecular biology techniques for protein expression and purification, providing a scalable and cost-effective solution for detecting and quantifying amino acids. Currently in the development stage, this technology...]]></description><pubDate>Fri, 21 Jan 2022 09:04:04 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/45777</guid></item><item><title>Development of a Novel Zebrafish Screening System and Identification of a Novel Protein That Induces Pancreatic Beta-Cell Proliferation</title><caseId>UO-15-09</caseId><link>http://icoregon.technologypublisher.com/technology/45776</link><description><![CDATA[This invention enables a novel, microbiome-derived approach to diabetes treatment by leveraging a protein from the gut bacterium Aeromonas that increases pancreatic &beta; cell number through enhanced proliferation, differentiation, and survival. By targeting restoration of insulin-producing &beta; cells, the technology addresses a core unmet need in Type I diabetes and offers potential disease-modifying benefits beyond glucose management.

The platform includes therapeutic proteins and domains, their encoding nucleic acids, recombinant vectors, and engineered cells, supporting multiple develo...]]></description><pubDate>Fri, 21 Jan 2022 08:50:32 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/45776</guid></item><item><title>Polymers from Carbon Nanohoop Building Blocks</title><caseId>UO-19-70</caseId><link>http://icoregon.technologypublisher.com/technology/45772</link><description><![CDATA[1. Technology Overview&nbsp;

The invention introduces polymers from carbon&nbsp;nanohoop&nbsp;building blocks, offering a scalable and cost-effective solution for enhancing the optoelectronic and mechanical properties of polymeric materials. These&nbsp;nanohoops&nbsp;are fused with a norbornene moiety to enable ring-opening metathesis polymerization (ROMP), resulting in novel polymers with tunable properties. The technology holds significant potential for applications in advanced materials, organic electronics, chemical sensors, and photovoltaic cells, providing improved performance and scala...]]></description><pubDate>Thu, 20 Jan 2022 13:55:16 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/45772</guid></item><item><title>Catalysis Inside of Radially-Oriented π-Systems</title><caseId>UO-18-34</caseId><link>http://icoregon.technologypublisher.com/technology/45771</link><description><![CDATA[1. Technology Overview&nbsp;

The invention focuses on catalysis inside&nbsp;radially-oriented&nbsp;T-systems using cycloparaphenylenes (CPPs), the smallest fragment of armchair carbon nanotubes (CNTs). These CPPs are synthesized with atomistic precision, incorporating meta-substituted pyridine units to position metals inside the hoop, enabling catalysis within these&nbsp;nanohoop&nbsp;architectures. The technology is currently in the development stage, with promising cross-industry applications in nanotechnology, materials science, and chemical synthesis.&nbsp;

2. Key Features and Benefits&n...]]></description><pubDate>Thu, 20 Jan 2022 13:52:40 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/45771</guid></item><item><title>Sensorless adaptive optics (AO) control method for OCT/OCT-angiography retinal imaging</title><caseId>2917</caseId><link>http://icoregon.technologypublisher.com/technology/45760</link><description>
Summary

Researchers have developed an improved method of adaptive optics for OCT/OCT-angiography retinal scanning that is sensorless and allows for optical aberrations correction without considerably increasing scan times.

Technology Overview

Adaptive optics OCT (AO-OCT) allows for high lateral resolution imaging of the retinal tissue and blood flow by compensating for ocular aberrations. However, translation of AO-OCT from the bench to clinic has been challenged by a number of factors, including large instrument footprint, high cost, narrow field of view (FOV), and long scan times. OHSU r...</description><pubDate>Wed, 19 Jan 2022 07:03:43 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45760</guid></item><item><title>Process for Recycling PVC to HDPE</title><caseId>OSU-21-34</caseId><link>http://icoregon.technologypublisher.com/technology/45572</link><description>Background

Approximately 40 million tons of polyvinyl chloride (PVC) are produced annually, making PVC one of the most widely produced synthetic plastic polymers. Waste materials that contain PVC are extremely difficult to recycle mechanically. Thermochemical methods such as pyrolysis are also undesirable because of hydrochloric acid and chlorinated organic byproducts that are produced by thermal decomposition of PVC. This process is a unique chemical method of converting PVC to a chlorine‑free polymer, such as high density polyethylene (HDPE), that is recyclable.

Technology Overview

The pr...</description><pubDate>Mon, 03 Jan 2022 15:10:01 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/45572</guid></item><item><title>mRNA Therapeutic Against the SARS-CoV-2 Spike Protein</title><caseId>OSU-20-43</caseId><link>http://icoregon.technologypublisher.com/technology/45525</link><description><![CDATA[&nbsp;Background

Vaccines have shown great efficacy against SARS-CoV-2, the pathogen of COVID-19; however, methods of treatment are required for patients suffering from COVID‑19. 

More than 15 million cases with over 600,000 deaths have resulted from the ongoing coronavirus disease 2019 (COVID-19). SARS-CoV-2, the pathogen of COVID-19, is a &beta;-coronavirus that primarily enters through the airways and lungs. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters through the airways and infects the lungs, causing lethal pulmonary damage in vulnerable patients. This virus conta...]]></description><pubDate>Thu, 16 Dec 2021 09:42:24 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/45525</guid></item><item><title>Treatment for Metabolic Syndrome and Obesity Related Diseases</title><caseId>OSU-20-78</caseId><link>http://icoregon.technologypublisher.com/technology/45518</link><description><![CDATA[Background

Abdominal obesity is the most commonly observed component of metabolic syndrome and a major risk factor for type II diabetes and cardiovascular disease. In addition to obesity, an individual&rsquo;s risk of cardiovascular disease and type II diabetes is strongly correlated to a series of risk factors, collectively referred to as metabolic syndrome, including insulin insensitivity, elevated plasma triglycerides, hypertension and low plasma high-density lipoproteins (HDLs). Reducing obesity and successfully preventing or treating metabolic syndrome medicinally remains a significant c...]]></description><pubDate>Wed, 15 Dec 2021 15:12:09 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/45518</guid></item><item><title>Fluorophores for multicolor microscopy</title><caseId>2205-D</caseId><link>http://icoregon.technologypublisher.com/technology/45468</link><description><![CDATA[SummaryMulticolor microscopy can be used to localize and visualize complex subcellular systems, but current systems are often limited in the number of fluorophores that can be imaged simultaneously.&nbsp; Oregon Health &amp; Science University researchers have developed novel fluorophores that increase the number of channels and subcellular structures that can be imaged in a single sample as compared to traditional fluorophores.Technology OverviewSuper resolution microscopy allows for tracking of single-molecules by utilizing photoswitchable fluorophores and compiling numerous images into one ...]]></description><pubDate>Thu, 02 Dec 2021 06:48:19 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45468</guid></item><item><title>The Active Workplace Toolkit</title><caseId>2923</caseId><link>http://icoregon.technologypublisher.com/technology/45446</link><description><![CDATA[
Summary

OHSU researchers have developed a set of training materials that provides organizations with tools and skills to promote physical activity and actively support safety, health, and well-being among their employees in a sedentary work environment.

Technology Overview

Sedentary work environments can be detrimental to the physical and emotional health of employees.&nbsp; Occupational health specialists at OHSU have developed the Active Workplace Toolkit, which is an adaptable safety, health, and well-being program designed specifically for the unique needs of sedentary occupations, the...]]></description><pubDate>Tue, 23 Nov 2021 13:10:14 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45446</guid></item><item><title>Improved high-security fork latch for fence gates</title><caseId>2279</caseId><link>http://icoregon.technologypublisher.com/technology/45366</link><description><![CDATA[
Summary

The current gate fork latch was designed with hidden fasteners, pivots and anti-rotation pins, making it much more difficult to remove by thieves, thereby improving its security and utility as compared to traditional fork latches.&nbsp; 

Technology Overview

Fork latches are ubiquitous and popular for gate closures, but they pose a significant security risk since a wrench can be used to remove the entire latch, with the lock attached, and open the gate.&nbsp; Furthermore, this kind of break-in can be done with no obvious signs of tampering to the latch, lock or gate, thus delaying d...]]></description><pubDate>Fri, 12 Nov 2021 07:20:27 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45366</guid></item><item><title>Methods of treating venetoclax-resistant acute myeloid leukemia</title><caseId>2648</caseId><link>http://icoregon.technologypublisher.com/technology/45365</link><description><![CDATA[SummaryAcute myeloid leukemia (AML) is difficult to treat due to the genetic heterogeneity of the disorder and accompanying drug resistance observed in many patients.&nbsp; Oregon Health &amp; Science University researchers have identified a new therapeutic approach to overcome venetoclax resistance and improve outcomes and prognoses for AML patients experiencing drug resistance.Technology OverviewBCL2 is commonly expressed in hematologic malignancies and is targeted by the therapeutic venetoclax to induce cell death in multiple leukemia cell lines. However, venetoclax is only modestly effecti...]]></description><pubDate>Fri, 12 Nov 2021 07:10:49 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45365</guid></item><item><title>Mutation-specific treatment strategies for acute myeloid leukemia</title><caseId>2561</caseId><link>http://icoregon.technologypublisher.com/technology/45364</link><description><![CDATA[
Summary

The implementation of targeted therapies for acute myeloid leukemia (AML) has been challenged by complex mutational patterns within and across patients as well as a dearth of pharmacologic agents for most mutational events. Oregon Health &amp; Science University (OHSU) researchers have identified treatment strategies for a broad scope of AML mutations. 

Technology Overview

Approximately 21,000 people are diagnosed with AML with over 10,000 AML- related deaths annually in the United States. Cytogenetic and sequencing analyses have previously revealed at least 11 genetic classes of A...]]></description><pubDate>Fri, 12 Nov 2021 06:59:22 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45364</guid></item><item><title>Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications</title><caseId>2956</caseId><link>http://icoregon.technologypublisher.com/technology/45185</link><description><![CDATA[
Summary

Rhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health &amp; Science University researchers have developed a water-soluble and cell-permeant rhodamine dye for improved quantitative imaging.

Technology Overview

Fluorescent proteins have become common optogenetic tools for investigating cell structures, functions, and underlying mechanisms of subcell...]]></description><pubDate>Wed, 27 Oct 2021 06:06:53 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45185</guid></item><item><title>Sleep Apnea Detection System</title><caseId>1342</caseId><link>http://icoregon.technologypublisher.com/technology/45162</link><description><![CDATA[
Summary

The current technology is a non-obtrusive system to monitor and diagnose sleep apnea and hypopnea.

Technology Overview 

Diagnosis of sleep apnea is most commonly performed using multiple night PSG studies at a sleep center attended by a clinician. These studies have several limitations, including multiple sensors needing to be worn by patients and an unfamiliar location both of which can disrupt sleep. 

OHSU has developed a non-obtrusive system to monitor and diagnose sleep apnea and hypopnea through the use of load cells installed in the supports of a patient&rsquo;s bed. The loa...]]></description><pubDate>Thu, 21 Oct 2021 11:49:11 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/45162</guid></item><item><title>RadSearch: a radiology report search engine</title><caseId>2817</caseId><link>http://icoregon.technologypublisher.com/technology/44949</link><description><![CDATA[
Summary

Harnessing the power of large databases is contingent upon the ability to access datapoints efficiently and accurately; however, this has proven difficult in the field of radiology where complex visual and written records must be integrated. Oregon Health &amp; Science University research has led to the development of a novel radiology-specific search engine and report classification method, RadSearch, to allow for quick and accurate queries of radiology reports providing the potential for improved patient care, education and research.  

Technology Overview

Radiology is well-suited...]]></description><pubDate>Thu, 23 Sep 2021 08:45:23 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44949</guid></item><item><title>Koala Kushion: an improved feeding positioner for infants</title><caseId>2986</caseId><link>http://icoregon.technologypublisher.com/technology/44937</link><description><![CDATA[
Summary

Reflux or feeding difficulties are common for infants, causing significant stress to parents and the prescription of unneeded medications. Oregon Health &amp; Science University healthcare professionals have developed the Koala Kushion, a positioner&nbsp;designed specifically to make feeding infants, with and without reflux, easier. 

Technology Overview

Reflux is a recurring condition affecting 2.5 million newborn infants each year, where breastmilk or formula are repeatedly spit-up during a critical growth period. This condition has a large impact on the healthcare system by causi...]]></description><pubDate>Tue, 21 Sep 2021 06:51:20 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44937</guid></item><item><title>EAR Tool: external auricular retrieval tool</title><caseId>2915</caseId><link>http://icoregon.technologypublisher.com/technology/44892</link><description>
Summary

A simple low-cost device to remove foreign objects from even small child-sized ear canals, potentially decreasing patient anxiety and the need for more expensive and invasive procedures. 

Technology Overview

Objects lodged in ears of children are a frequent reason for emergency department visits, but no retrieval tools exist that are small enough for child-sized ear canals and deep sedation and/or surgery are often required to remove the objects. OHSU researcher and emergency room physician Dr. David Sheridan has designed a simple device, called the external auricular retrieval (EA...</description><pubDate>Thu, 09 Sep 2021 14:41:03 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44892</guid></item><item><title>Inclusive Language Guide</title><caseId>3053</caseId><link>http://icoregon.technologypublisher.com/technology/44880</link><description><![CDATA[
Summary

A cross-departmental assembly of Oregon Health &amp; Science University (OHSU) members has developed a guide for inclusive language, which can be used by businesses, universities and hospitals to educate staff and promote diversity. 

Technology Overview

The Inclusive Language Guide is intended as a tool to help employers and employees learn about and use inclusive language in institutional communications, patient care (including chart notes), instruction and presentations around descriptors of:


	Race and ethnicity
	Immigration status
	Gender and sexual orientation
	Ability (inclu...]]></description><pubDate>Wed, 08 Sep 2021 09:30:06 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44880</guid></item><item><title>My Pregnancy Plate</title><caseId>2241</caseId><link>http://icoregon.technologypublisher.com/technology/44677</link><description><![CDATA[SummaryOregon Health &amp; Science University dietitian Christie Naze has developed an easy visual guide to proper nutrition during pregnancy.Materials OverviewProper nutrition during pregnancy is critical for a baby's health, both during development and later in life; however, excessive weight gain during pregnancy is common and associated with an increased risk for several conditions including gestational diabetes and cesarean section delivery. The My Pregnancy Plate graphic was developed to be a visual aid towards proper nutrition during pregnancy.&nbsp; In addition to the helpful images of...]]></description><pubDate>Tue, 17 Aug 2021 08:24:26 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44677</guid></item><item><title>Quantification of vascular abnormality with OCT angiography</title><caseId>2062</caseId><link>http://icoregon.technologypublisher.com/technology/44468</link><description>
Summary

Current OCT techniques are limited in their ability to accurately detect vasculature changes, and patients with retinal vascular diseases often require more invasive intravenous contrast dye-based angiography procedures. The current technology is an OCT-based non-injection, dye-free method that allows for 3D visualization of superimposed structural and angiography data to improve detection of vascular pathologies. 

Technology Overview

Optical coherence tomography (OCT) has become the standard imaging modality in ophthalmology for evaluating fluid accumulation in retinal vascular di...</description><pubDate>Tue, 03 Aug 2021 07:03:16 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44468</guid></item><item><title>Forward scanning vitrectomy OCT microprobe</title><caseId>1757</caseId><link>http://icoregon.technologypublisher.com/technology/44306</link><description>
Summary

The practical employment of OCT probes in surgeries of solid organs or internal cavities has been limited by the lack of miniature forward-scanning probes. Dr. David Huang and colleagues have developed a small forward-scanning OCT vitrectomy probe that would allow for the incorporation of OCT into probe-guided procedures for a variety of organs.

Technology Overview

Most current OCT probes are side scanning, but forward imaging probes are needed in situations where the OCT image itself is used to guide the advance and positioning of the probe in a solid organ (i.e. brain, breast) or...</description><pubDate>Mon, 19 Jul 2021 06:26:39 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44306</guid></item><item><title>Subtyping autism using a novel machine learning method</title><caseId>2556</caseId><link>http://icoregon.technologypublisher.com/technology/44228</link><description><![CDATA[
Summary

Autism spectrum&nbsp;disorder (ASD) is a heterogenous disease, making it difficult to develop diagnostic measures and effective treatments. Oregon Health and Science University researchers have developed a novel AI method for identifying ASD subgroups, which could help refine ASD diagnostic criteria and further the study of precision medicine for individuals with ASD.

Technology Overview

The prevalence of ASD is increasing globally, but the variability in symptoms, severity and adaptive behavioral impairments makes the disease difficult to diagnose and treat. The laboratory of Dr. ...]]></description><pubDate>Tue, 06 Jul 2021 15:13:35 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44228</guid></item><item><title>Compositions for treatment of neurological and oxidative stress disorders</title><caseId>2750</caseId><link>http://icoregon.technologypublisher.com/technology/44048</link><description><![CDATA[
Summary

Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health &amp; Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. 

Technology Overview

The mitochondrial permeability transition pore (mtPTP) plays a key role in a wide variety of human diseases whose common pathology may be based in mitochondrial dysfunction; however, there are few small molecule inhibitors of mtPT...]]></description><pubDate>Tue, 22 Jun 2021 11:11:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/44048</guid></item><item><title>Systems and methods for retinal capillary oximetry</title><caseId>2714</caseId><link>http://icoregon.technologypublisher.com/technology/43864</link><description>
Summary
A system and method to assess the blood oxygen saturation in retinal vessels and capillaries, in high resolution. This invention can quantify the oxygen saturation in a single capillary using a non-invasive and dye-free technique.

Technology Overview
Altered oxygen supply is thought to be a critical factor underlying many retinal disorders that may precede loss of visual acuity and observable changes in vascular morphology. If quantified accurately, blood oxygen saturation could be used as a biomarker to monitor retinal metabolism, predict its pathologies, and can serve as a valuable...</description><pubDate>Wed, 09 Jun 2021 15:35:45 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43864</guid></item><item><title>Versatile Interacting Peptide tags for high resolution microscopy</title><caseId>2270</caseId><link>http://icoregon.technologypublisher.com/technology/43843</link><description><![CDATA[
Summary

Researchers at OHSU have developed a novel system for tracking multiple cellular proteins using genetically encoded peptide tags, which are smaller than antibodies and demonstrate greater labeling efficiency, expanding the capabilities of existing imaging and microscopy techniques. 

Technology Overview

Protein labeling methods often rely on large, bulky molecules (such as, fluorescent proteins, labeled antibodies and protein tags), which can interfere with the target protein&rsquo;s activity and subcellular localization, and are limited in their color options for techniques such as...]]></description><pubDate>Tue, 08 Jun 2021 07:18:57 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43843</guid></item><item><title>Visual field simulation using OCT and OCT angiography</title><caseId>2658</caseId><link>http://icoregon.technologypublisher.com/technology/43825</link><description><![CDATA[Summary
Preventing glaucoma disease progression requires regular monitoring and timely treatment. However, current assessment of visual field loss is subjective and can be unreliable for monitoring small progressive vision loss. Accordingly, Dr. David Huang et al. developed an OCTA test that produces simulated visual fields. The test provides a more objective and more reliable test than the conventional visual field method to assess progressive visual field deficits in mild to moderate disease stage glaucoma.&nbsp; &nbsp;

Technology Overview
Effective monitoring of glaucoma patients requires ...]]></description><pubDate>Fri, 04 Jun 2021 12:33:46 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43825</guid></item><item><title>Remote endarterectomy device</title><caseId>2421</caseId><link>http://icoregon.technologypublisher.com/technology/43823</link><description>
Summary

A surgical device comprising design features to allow flexibility and differential size accommodations for peripheral vascular plaque removal. 

Technology Overview

In the United States alone, 8-12 million people have peripheral arterial disease. These numbers are increasing due to persistent risk factors such as smoking, diabetes, and age. Remote endarterectomy is used in peripheral vascular surgery to remove plaque from an occluded femoral artery. Products currently used by surgeons have limited flexibility with a fixed diameter metal ring that cannot accommodate changes in the si...</description><pubDate>Fri, 04 Jun 2021 06:42:48 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43823</guid></item><item><title>Novel device for ultrasound-assisted IV placement</title><caseId>2685</caseId><link>http://icoregon.technologypublisher.com/technology/43740</link><description><![CDATA[
Summary

Intravenous (IV) lines are placed over 200 million times per year, but difficulties occur in securing proper placement in a large percentage of cases, approximately 20-30%. Oregon Health &amp; Science University researchers have developed a novel device to allow for easier execution of ultrasound-guided IV placement. 

Technology Overview

IV lines are difficult to place in a growing patient population, including those with obesity and vein damage due to IV drug use, chronic renal disease, or chemotherapy. Patients with difficult access experience delays in lab tests and pain medicat...]]></description><pubDate>Wed, 19 May 2021 14:35:08 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43740</guid></item><item><title>Bioactive polymers with anti-fouling properties for medical implants</title><caseId>2850</caseId><link>http://icoregon.technologypublisher.com/technology/43590</link><description><![CDATA[
Summary

The development of bacterial biofilms can affect the structural integrity of in-dwelling medical devices and materials, reducing their longevity. Oregon Health &amp; Science University researchers have developed bioactive polymers, which are compatible with traditional dental reconstruction materials and reduce biofilm formation to potentially increase the durability of medical implants, including dental restorations.

&nbsp;

Technology Overview

Indwelling medical devices and materials are highly susceptible to bacterial colonization, and these bacterial biofilms can be detrimental...]]></description><pubDate>Tue, 11 May 2021 06:49:48 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43590</guid></item><item><title>LIGHTNING™ Barley (DH130910)</title><caseId>OSU-20-50</caseId><link>http://icoregon.technologypublisher.com/technology/43579</link><description><![CDATA[Technology Description

Lightning &ndash; this is the first facultative two-row multi-use variety in the world! It was developed by Oregon State University (OSU). The variety has excellent disease resistance, resistance to pre-harvest, sprouting, and will be a high yielding variety for those interested in producing barley for feed, pearling, and/or able to adjust malting parameters to achieve suitable quality for brewing and distilling. When fall-planted, in the Pacific Northwest, west of the Cascades, Lightning has a 20 bushel/acre yield advantage over these varieties. Heading dates are compa...]]></description><pubDate>Mon, 10 May 2021 09:34:03 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/43579</guid></item><item><title>Tomographic bright field imaging (TBFI)</title><caseId>1791</caseId><link>http://icoregon.technologypublisher.com/technology/43471</link><description>
Summary

Tomographic bright field image analysis enables the three-dimensional measurement of engineered and biological specimens without the requirement of sample labeling or expensive specialized optical equipment. This novel software offers the unique advantage of true quantitative image analysis of factors like mass and density and could provide a novel way of tracking cellular structure and dynamics over time.

Technology Overview

Current bright field imaging techniques (i.e. dark field, bright field, phase, differential interreference contrast, etc.) remain largely qualitative, prevent...</description><pubDate>Tue, 27 Apr 2021 06:17:47 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43471</guid></item><item><title>Antibacterial monomers for dental applications</title><caseId>2687</caseId><link>http://icoregon.technologypublisher.com/technology/43441</link><description><![CDATA[
Summary

Oregon Health &amp; Science University researchers have developed a novel monomer adhesive with increased antibacterial properties compared to existing adhesives, which may reduce infection and increase the longevity of dental restorations.

Technology Overview

Biofilm colonization of restorative surfaces is one of the main issues leading to secondary caries, which in turn is one of the leading causes for replacement. The laboratory of Dr. Carmem Pfeifer has developed a novel class of monomers with antibacterial properties. These compounds demonstrate similar structural and mechanic...]]></description><pubDate>Tue, 20 Apr 2021 14:07:29 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43441</guid></item><item><title>Polymerizable compounds for applications in dental materials</title><caseId>2482</caseId><link>http://icoregon.technologypublisher.com/technology/43414</link><description><![CDATA[Summary
Adhesives are widely used in dentistry to create a bond between teeth and restorative material, but current commercially available dental adhesives are often acidic and undergo degradation in the aqueous oral environment. Oregon Health &amp; Science University researchers have developed an acrylamide based dental adhesive with reduced degradation resulting in a more stable and long-lasting seal of the tooth-filing interface. 

Technology Overview
Current dental adhesives often contain methacrylates and high concentrations of hydrophilic and/or ionic monomers, resulting in high levels o...]]></description><pubDate>Wed, 14 Apr 2021 10:53:00 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43414</guid></item><item><title>Self-tracking real-time high-resolution wide-field OCT angiography (OCTA)</title><caseId>2837</caseId><link>http://icoregon.technologypublisher.com/technology/43404</link><description><![CDATA[
Summary

Optical coherence tomographic angiography (OCTA) provides superior resolution and volumetric data compared to fluorescein angiography, but this 3D technology requires motion artifact compensation caused by movements during the scan. Oregon Health &amp; Science University researchers have developed a method to suppress motion artifacts caused by eye motion and blinking in real-time during OCTA scans without requiring any additional hardware. 

Technology Overview

OCTA provides high-resolution angiographic data by measuring inherent motion contrast between successive OCT images; howev...]]></description><pubDate>Tue, 13 Apr 2021 08:04:07 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43404</guid></item><item><title>High Efficiency Carbon-Based Micro-LED</title><caseId>OSU-19-50</caseId><link>http://icoregon.technologypublisher.com/technology/43337</link><description>Carbon-based materials for efficient, inexpensive, and tunable micro-LED display applications 

Background   
Micro light emitting diode (micro-LED) display is emerging as a candidate to drive a new generation of display technology. LED-based light sources are also widely used in lighting applications. It remains a challenge to develop cost-effective color conversion micro-LED technologies with enhanced light emission efficiency and minimized excitation light leakage through its color conversion layer. Carbon dots are also an emerging material for micro-LEDs as an alternative to more expensive...</description><pubDate>Thu, 01 Apr 2021 10:41:51 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/43337</guid></item><item><title>A method to regenerate vascularized dental pulp for root canal dental therapy</title><caseId>2228</caseId><link>http://icoregon.technologypublisher.com/technology/43328</link><description><![CDATA[Summary
Current root canal therapies rely on removing necrotic tissue and filling the area with inert material, reducing vascularity in the dental pulp and overall health in the remaining tooth.&nbsp; The laboratory of Dr. Luiz Bertassoni has developed a novel root canal treatment that features a hydrogel filling with a hollow central chamber, which can be seeded with endothelial cells and potentially promote vascularization after root canal.&nbsp; 

Technology Overview
The biological function of the dental pulp is primarily regulated via the vasculature; therefore, novel root canal strategies...]]></description><pubDate>Wed, 31 Mar 2021 11:58:43 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43328</guid></item><item><title>"Tooth on a chip"- A microfluidic device to test interactions of biomaterials with dental structures</title><caseId>2544</caseId><link>http://icoregon.technologypublisher.com/technology/43326</link><description><![CDATA[
Summary

The development of novel dental biomaterials requires in vitro validation and cytotoxicity studies; however, research platforms that accurately emulate the oral environment, the interface between biomaterials with the tooth, and the underlying dental pulp, do not currently exist. This is traditionally done by exposing plated cells to eluents of biomaterials, or using animal models. OHSU researcher Dr. Luiz Bertassoni has developed the first-of-its-kind tooth-on-a-chip platform that replicates both the tooth&#39;s key components to test dental materials in a more clinically relevant m...]]></description><pubDate>Wed, 31 Mar 2021 11:51:13 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/43326</guid></item><item><title>Radiation-enhanced delivery of antisense oligonucleotides against MGMT</title><caseId>2291</caseId><link>http://icoregon.technologypublisher.com/technology/42835</link><description><![CDATA[
Summary

MGMT is a critical enzyme driving DNA repair, and down-regulation of this molecule in tumors is linked to increased efficacy of cancer therapies that promote DNA damage and apoptosis of cancer cells. Researchers at the Veteran&rsquo;s Affair Hospital and Oregon Health &amp; Science University have developed a new cancer therapeutic strategy consisting of anti-MGMT morpholino oligonucleotides (AMON), which, when used with traditional radiation therapy, can be locally-delivered and cross the blood brain barrier for treatment of brain cancer. 

Technology Overview

Alkylating chemothera...]]></description><pubDate>Thu, 28 Jan 2021 15:00:08 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/42835</guid></item><item><title>Snow Pea Exp. S1431</title><caseId>OSU-20-60</caseId><link>http://icoregon.technologypublisher.com/technology/42507</link><description>Technology Description

The S1431 is a snow or Chinese pea with large, low-fiber and tasty medium-green pods intended for organic production. They should be harvested when pods are still flat and seeds have not yet developed. This cultivar is a tall vine with the first node at about 3.3 feet and should be trained to a trellis to facilitate multiple hand pickings over the growing season. They have smooth, round seed that have been selected for good germination and emergence in cool soils without the application of fungicide seed. S1431 has an excellent disease package with durable resistance to...</description><pubDate>Thu, 03 Dec 2020 09:59:30 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/42507</guid></item><item><title><![CDATA[Snap Pea Exp. S1423 & 1430]]></title><caseId>OSU-20-59</caseId><link>http://icoregon.technologypublisher.com/technology/42505</link><description><![CDATA[Technology Description

S1423 and S1430 are a pair of tall-vined snap peas that were bred for production under organic conditions. They have dimpled seed that has been selected for good germination and emergence in cool soils without the application of fungicide seed treatments. The flavorful pods are medium green in color, thick-walled and succulent and have suture strings. They should be trained to a trellis to facilitate multiple hand pickings over the growing season. Height to first node is about 2&frac12; ft for S1423 and 3 ft for S1430. The cultivars have an excellent disease package wit...]]></description><pubDate>Thu, 03 Dec 2020 09:55:23 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/42505</guid></item><item><title>Morpholino Oligomers to Prevent and Treat Coronavirus Infection</title><caseId>OSU-20-27</caseId><link>http://icoregon.technologypublisher.com/technology/42473</link><description>

This technology licensing opportunity relates to antisense agents for treating or preventing a SARS-CoV-2 infection. The antisense agents are peptide-conjugated morpholino oligomers targeting pre-mRNA of a host (human) gene that encodes a protease. Some antisense agents included within the scope of this technology include agents previously shown to be useful against influenza, however, new antisense agents are also envisioned. The novelty of applying the agents against SARS-CoV-2 infection lies in the discovery that the targeted protease is required for efficient SARS-CoV-2 infectivity.

In ...</description><pubDate>Tue, 24 Nov 2020 12:29:50 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/42473</guid></item><item><title>Blood Separation and Diagnostic Device</title><caseId>OSU-19-30</caseId><link>http://icoregon.technologypublisher.com/technology/42466</link><description>Technology Description

Oregon State University is seeking a licensee to develop and commercialize products based on a patent pending membrane device that provides a platform for blood separation and analysis. This device is a simple Janus-type membrane-based wicking microfluidic device fabricated on a polycaprolactone-filled glass microfiber membrane which enables separation of blood plasma/serum from whole blood, followed by collection. This device can be integrated with many chemistries and assays to develop inexpensive point-of-care diagnostic devices. It can also be used as a sample prepa...</description><pubDate>Mon, 23 Nov 2020 10:41:39 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/42466</guid></item><item><title>The FOoD Kitchen</title><caseId>2191</caseId><link>http://icoregon.technologypublisher.com/technology/41872</link><description><![CDATA[
Technology Overview 

This is a cookbook designed for patients with a long-chain fatty acid oxidation disorder. The recipes are low in fat with added MCT oil. There are some great ideas about how to use MCT oil in cooking everything from main dishes and salads to desserts. Enjoy cooking some new recipes that are designed specifically for you.

The cookbook can be previewed here.

The cookbook can be ordered here.&nbsp;]]></description><pubDate>Wed, 16 Sep 2020 14:11:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41872</guid></item><item><title>Recombinant human CD74 for cancer and immunology research</title><caseId>2219</caseId><link>http://icoregon.technologypublisher.com/technology/41867</link><description><![CDATA[
Summary&nbsp;
A recombinant chimeric version of CD74 containing the human extracellular domain, which binds MIF-1 and MIF-2 and has the potential as a valuable research tool for cancer and immunology studies examining the CD74-MIF axis. 

Technology Overview
CD74 interactions with migration inhibitory factor (MIF) is a growing area of cancer and immunology research.&nbsp; However, current recombinant versions of CD74 have a limited ability to bind MIF.&nbsp; Researchers at OHSU have developed an E. coli-expressed recombinant version of human CD74 with the following properties:


	Improved bin...]]></description><pubDate>Wed, 16 Sep 2020 13:59:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41867</guid></item><item><title>Diagnostic classification and questionnaire for facial pain</title><caseId>2271</caseId><link>http://icoregon.technologypublisher.com/technology/41866</link><description>
Technology Overview
This Facial Pain Survey is a helpful questionnaire for the diagnosis and treatment of patients suffering from varies types of trigeminal neuralgia.
Licensing Opportunity
This survey is available for licensing.</description><pubDate>Wed, 16 Sep 2020 13:59:33 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41866</guid></item><item><title>ImmortaMAITs: immortalized Mucosal Associated Invariant T (MAIT) cells as new human cell line reagents for human immunobiology research</title><caseId>2274</caseId><link>http://icoregon.technologypublisher.com/technology/41865</link><description><![CDATA[
Technology Overview

The Immorta-MAITs are human mucosal-associated invariant T (MAIT) cells.&nbsp; There are ten cell lines which are confirmed to express the MAIT T cell receptor alpha (TRAV1-2) and full TCR sequencing has been performed.&nbsp; The cell lines stain with an MR1-tetramer loaded with a MAIT antigen 5-OP-RU and not control MR1-tetramer loaded with 6FP.&nbsp; The Immorta-MAITs are able to grow in a simple media without the addition of cytokines, human serum, or stimulation.&nbsp; These cell lines are clonal and were generated by single cloning methods from healthy thymus tissue ...]]></description><pubDate>Wed, 16 Sep 2020 13:59:17 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41865</guid></item><item><title>The Drug Information Database web application</title><caseId>2392</caseId><link>http://icoregon.technologypublisher.com/technology/41862</link><description>
Technology Overview

The Drug Information (DI) Database is a web application for receiving, archiving and searching consults and drug requests. In particular, it offers a simple end-user application that allows easy navigation and access for both healthcare professionals as well as patient from multiple device types.

Licensing Opportunity

This technology is available for licensing.</description><pubDate>Wed, 16 Sep 2020 13:55:27 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41862</guid></item><item><title>Polyclonal rabbit antibody to gonadotropin-releasing hormone (GnRH)</title><caseId>2422</caseId><link>http://icoregon.technologypublisher.com/technology/41861</link><description><![CDATA[
Technology Overview

A rabbit polyclonal antibody made against gonadotropin-releasing hormone (GnRH) that is highly specific to mammalian, fish and avian forms of GnRH and has been validated for use in immunohistochemistry and hormone assay systems.

Publication

Urbanski HF, et al., &ldquo;The influence of photoperiod and 6-methoxybenzoxazolinone on the reproductive axis of inbred LSH/Ss Lak male hamsters.&rdquo; Journal of Reproduction and Fertility, 90 (1990): 157-163. Link

Licensing Opportunity

This antibody is available for licensing.]]></description><pubDate>Wed, 16 Sep 2020 13:55:04 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41861</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Gerry</title><caseId>1221-F</caseId><link>http://icoregon.technologypublisher.com/technology/41859</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-F is 
the&nbsp;Gerry strain.
Inventor ProfileDr. Jay Nelson...]]></description><pubDate>Wed, 16 Sep 2020 13:53:00 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41859</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Edding</title><caseId>1221-E</caseId><link>http://icoregon.technologypublisher.com/technology/41858</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-E is 
the&nbsp;Edding strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Wed, 16 Sep 2020 13:52:46 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41858</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Dement</title><caseId>1221-D</caseId><link>http://icoregon.technologypublisher.com/technology/41856</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-D is 
the&nbsp;Dement strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Wed, 16 Sep 2020 13:52:22 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41856</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Davis</title><caseId>1221-C</caseId><link>http://icoregon.technologypublisher.com/technology/41855</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-C is 
the&nbsp;Davis strain.
Inventor ProfileDr. Jay Nelson...]]></description><pubDate>Wed, 16 Sep 2020 13:52:00 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41855</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Brown</title><caseId>1221-B</caseId><link>http://icoregon.technologypublisher.com/technology/41854</link><description><![CDATA[&nbsp;Technology 
Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-B is 
the&nbsp;Brown strain.
Inventor ProfileDr. Jay...]]></description><pubDate>Wed, 16 Sep 2020 13:51:13 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41854</guid></item><item><title>The Pacific Northwest Anti-Inflammatory Reference Cookbook</title><caseId>1162-A</caseId><link>http://icoregon.technologypublisher.com/technology/41847</link><description><![CDATA[
Summary

Are you curious about the Anti-Inflammatory diet and ready for a change in your eating habits?&nbsp; This reference cookbook will be valuable to anyone interested in the nutritional content of anti-inflammatory foods. There are over&nbsp;61 delicious recipes as well as suggested menus, nutrient analysis, cooking tips, and helpful shopping information.&nbsp;Given its avoidance of many pro-allergenic foods, patients with food sensitivities or allergies may find this diet particularly helpful.

&nbsp;

Technology Summary

This cookbook was created at Oregon Health &amp; Science Universi...]]></description><pubDate>Wed, 16 Sep 2020 13:40:34 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41847</guid></item><item><title>HPd2 monoclonal antibody supernatant from hybridoma DHIC3-5H10 (duct cell marker)</title><caseId>1038K</caseId><link>http://icoregon.technologypublisher.com/technology/41840</link><description><![CDATA[
Technology Overview

The monoclonal antibody HPd2 is derived from the hybridoma DHIC3-5H10. HPd2 selectively reacts with a cell surface molecule on human pancreatic duct cells.

Antibody:&nbsp;HPd2 Supernatant
Hybridoma cell line:&nbsp;DHIC3-5H10
Isotype:&nbsp;Mouse IgM
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp;1mL supernatant aliquot.]]></description><pubDate>Wed, 16 Sep 2020 13:37:38 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41840</guid></item><item><title>HPd1 monoclonal antibody supernatant from hybridoma DHIC2-4A10 (duct cell marker)</title><caseId>1038J</caseId><link>http://icoregon.technologypublisher.com/technology/41839</link><description><![CDATA[
Technology Overview

The monoclonal antibody HPd1 is derived from the hybridoma DHIC2-4A10. HPd1 selectively reacts with a cell surface molecule on human pancreatic duct cells.

Antibody:&nbsp;HPd1 Supernatant
Hybridoma cell line:DHIC2-4A10
Isotype:&nbsp;Mouse IgG1
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:1mL supernatant aliquot.]]></description><pubDate>Wed, 16 Sep 2020 13:37:29 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41839</guid></item><item><title>HPx2 monoclonal antibody supernatant from hybridoma HIC1-1C10 (exocrine cell marker)</title><caseId>1038I</caseId><link>http://icoregon.technologypublisher.com/technology/41838</link><description><![CDATA[
Technology Overview
The monoclonal antibody HPx2 is derived from the hybridoma HIC1-1C10.&nbsp; HPx2 selectively reacts with a cell surface module on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types.

Antibody:&nbsp;HPx2 Supernatant
Hybridoma cell line:&nbsp;HIC1-1C10
Isotype:&nbsp; Mouse IgM
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL supernatant aliquot.

&nbsp;]]></description><pubDate>Wed, 16 Sep 2020 13:37:19 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41838</guid></item><item><title>HPa2 Monoclonal Antibody Supernatant from Hybridoma DHIC2-2B4 (alpha cell marker)</title><caseId>1038H</caseId><link>http://icoregon.technologypublisher.com/technology/41837</link><description><![CDATA[
Technology Overview


The monoclonal antibody HPa2 is derived from the hybridoma DHIC2-2B4.&nbsp; HPa2 selectively reacts with a cell surface module on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types.

&nbsp;


Antibody:&nbsp;HPa2 Supernatant
Hybridoma cell line:&nbsp;DHIC2-2B4
Isotype:&nbsp;Mouse IgM
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL supernatant aliquot.


&nbsp;]]></description><pubDate>Wed, 16 Sep 2020 13:37:11 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41837</guid></item><item><title>HPa1 monoclonal antibody supernatant from hybridoma DHIC2-2C12 (alpha cell marker)</title><caseId>1038G</caseId><link>http://icoregon.technologypublisher.com/technology/41836</link><description><![CDATA[
Technology Overview

&nbsp;The monoclonal antibody HPa1 is derived from the hybridoma DHIC2-2C12.&nbsp; HPa1 selectively reacts with a cell surface module on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types.
&nbsp;

Antibody:&nbsp;HPa1 Supernatant
Hybridoma cell line:&nbsp;DHIC2-2C12
Isotype:&nbsp;Mouse IgM
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL supernatant aliquot.


&nbsp;]]></description><pubDate>Wed, 16 Sep 2020 13:37:02 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41836</guid></item><item><title>FITC conjugated HPs1 monoclonal antibody supernatant from hybridoma HIC0-3C5 (islet cell subset marker)</title><caseId>1038F-1</caseId><link>http://icoregon.technologypublisher.com/technology/41835</link><description><![CDATA[
Technology Overview


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The monoclonal antibody HPs1 is derived from hybridoma HIC0-3C5 and conjugated to FITC.&nbsp; HPs1 selectively reacts with a cell surface module on human pancreatic endocrine cells. This antibody reacts with islet cell subset...]]></description><pubDate>Wed, 16 Sep 2020 13:36:51 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41835</guid></item><item><title>HPs1 monoclonal antibody supernatant from hybridoma HIC0-3C5 (islet cell subset marker)</title><caseId>1038F</caseId><link>http://icoregon.technologypublisher.com/technology/41834</link><description><![CDATA[
The monoclonal antibody HPs1 is derived from hybridoma HIC0-3C5.&nbsp; HPs1 selectively reacts with a cell surface module on human pancreatic endocrine cells. This antibody reacts with islet cell subsets.

&nbsp;

&nbsp;

Antibody:&nbsp;HPs1 Supernatant
Hybridoma cell line:&nbsp;HIC0-3C5
Isotype:&nbsp;Mouse IgM
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL supernatant aliquot.]]></description><pubDate>Wed, 16 Sep 2020 13:36:41 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41834</guid></item><item><title>APC conjugated HPi2 antibody from hybridoma HIC1-2B4 (endocrine cell marker)</title><caseId>1038B-2</caseId><link>http://icoregon.technologypublisher.com/technology/41833</link><description><![CDATA[
Technology Overview

This APC conjugated monoclonal antibody HPi2 is derived from the hybridoma HIC1-2B4.&nbsp; HPi2 selectively reacts&nbsp;with a cell surface module on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types.

&nbsp;

Antibody:&nbsp;HPi2 Supernatant
Hybridoma cell line:&nbsp;HIC1-2B4
Isotype:&nbsp;Mouse IgG1
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL supernatant aliquot.]]></description><pubDate>Wed, 16 Sep 2020 13:36:31 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41833</guid></item><item><title>Purified HPi2 antibody from hybridoma HIC1-2B4 (endocrine cell marker)</title><caseId>1038B-1</caseId><link>http://icoregon.technologypublisher.com/technology/41832</link><description><![CDATA[
Technology Overview

The monoclonal antibody HPi2 is derived from the hybridoma HIC1-2B4.&nbsp; HPi2 selectively reacts&nbsp;with a cell surface module on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types.

&nbsp;

Antibody:&nbsp;HPi2 Supernatant
Hybridoma cell line:&nbsp;HIC1-2B4
Isotype:&nbsp;Mouse IgG1
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL purified antibody aliquot.]]></description><pubDate>Wed, 16 Sep 2020 13:36:22 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41832</guid></item><item><title>HPi2 monoclonal antibody supernatant from hybridoma HIC1-2B4 (endocrine cell marker)</title><caseId>1038B</caseId><link>http://icoregon.technologypublisher.com/technology/41831</link><description><![CDATA[
Technology Overview


The monoclonal antibody HPi2 is derived from the hybridoma HIC1-2B4.&nbsp; HPi2 selectively reacts&nbsp;with a cell surface module on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types.

&nbsp;

Antibody:&nbsp;HPi2 Supernatant
Hybridoma cell line:&nbsp;HIC1-2B4
Isotype:&nbsp;Mouse IgG1
Species reactivity:&nbsp;Human
Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry
Availability:&nbsp; 1mL supernatant aliquot.

&nbsp;

&nbsp;

&nbsp;]]></description><pubDate>Wed, 16 Sep 2020 13:36:13 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41831</guid></item><item><title>HPi1 monoclonal antibody supernatant from hybridoma HIC0-4F9 (endocrine cell marker)</title><caseId>1038A</caseId><link>http://icoregon.technologypublisher.com/technology/41830</link><description><![CDATA[
Technology Overview

The monoclonal antibody HPi1 is derived from the hybridoma HIC0-4F9. HPi1 selectively reacts with a cell surface molecule on human pancreatic endocrine cells. This antibody reacts with multiple endocrine cell types. 

&nbsp;

Antibody:&nbsp;HPi1 Supernatant

Hybridoma cell line:&nbsp;HICO-4F9

Isotype:&nbsp;Mouse IgG1

Species reactivity:&nbsp;Human

Applications:&nbsp;Immunohistochemistry (acetone fixation recommended), Flow cytometry

Availability:&nbsp; 1mL supernatant aliquot

&nbsp;]]></description><pubDate>Wed, 16 Sep 2020 13:36:03 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41830</guid></item><item><title>Sigma-point filter-nased integrated navigation system</title><caseId>0786</caseId><link>http://icoregon.technologypublisher.com/technology/41822</link><description>
Summary

This technique achieves for the navigational state of the system an estimation accuracy that is greater than that achievable with an extended Kalman filter-based probabilistic inference system.

Technology Overview

USA Today reports that the U.S. military, encouraged by the success of satellite-guided bombs and unmanned spy planes, plans to spend $10 billion between now and 2010 on unmanned vehicles. Small, unmanned aerial vehicles represent one such application. Currently, the internal monitoring unit and software for small unmanned aerial vehicles cost approximately $10,000-$15,00...</description><pubDate>Wed, 16 Sep 2020 13:34:21 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41822</guid></item><item><title>Diagnosis of human malignances associated with activating mutations of platelet derived growth factor receptor alpha (PDGFRA)</title><caseId>0614</caseId><link>http://icoregon.technologypublisher.com/technology/41795</link><description><![CDATA[
Summary

The current technology consists of several novel PDGFRA variant proteins, and nucleic acids encoding these variants along with methods of using these molecules in detecting biological conditions associated with an activating PDGFRA mutation. 

Technology Overview

Tyrosine kinases are expressed in many human cancers and are attractive targets for the development of anticancer therapies. Clinical response to these therapies is often correlated with the mutational status of the target.&nbsp; The identification of a particular mutation in a patient&rsquo;s tumor therefore can be used to...]]></description><pubDate>Wed, 16 Sep 2020 13:26:16 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41795</guid></item><item><title>Antisense Agents for Treating SARS-CoV-2 Infection</title><caseId>OSU-20-33</caseId><link>http://icoregon.technologypublisher.com/technology/41481</link><description>Background   
In December 2019, cases of an acute respiratory disease were reported from Wuhan, the capital of Hubei province in China. The number of infections increased rapidly and spread to other areas of China and on January 13th, 2020, the first case was reported outside of China. The causative agent was identified as a novel coronavirus (CoV) of the lineage b of the genus Betacoronavirus that also includes the 2002 SARS-CoV that caused a global outbreak of severe acute respiratory syndrome (SARS) in 2002 and 2003. The newly-emerged CoV was named SARS-CoV-2 by the World Health Organizatio...</description><pubDate>Wed, 09 Sep 2020 20:28:29 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/41481</guid></item><item><title>Small molecules promoting nerve regeneration</title><caseId>2944</caseId><link>http://icoregon.technologypublisher.com/technology/41446</link><description><![CDATA[
Summary

Nerve regeneration is critical after an injury for proper healing and restoration of function, but many tissues, such as the heart and spinal cord, lack this capacity due to extensive scarring resulting in more permanent injury and loss of function. Researchers at Oregon Health &amp; Science have discovered novel compounds that promote nerve regeneration in tissues that normally undergoing scarring.

&nbsp;

Technology Overview

Nerve damage is a major complication following myocardial infarction, traumatic brain injury, and spinal cord injury. The etiologies of these injuries are di...]]></description><pubDate>Mon, 31 Aug 2020 15:22:43 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41446</guid></item><item><title>Adaptive exercise-enabled proportional-derivative artificial pancreas control algorithm</title><caseId>2526</caseId><link>http://icoregon.technologypublisher.com/technology/41271</link><description><![CDATA[
Summary

The current technology is an adaptive proportional-derivative (APD) control algorithm that provides automated delivery amounts of insulin and optionally glucagon to a person with type 1 diabetes using continuous glucose measurements (CGM) sensed from the person&rsquo;s subcutaneous tissue.&nbsp; The APD algorithm includes a safety layer decision tree to prevent dosing of insulin and glucagon under certain physician-specified conditions.

Technology Overview

The APD algorithm includes a method for adapting postprandial insulin amounts in response to prior postprandial hypoglycemia ep...]]></description><pubDate>Thu, 13 Aug 2020 10:05:01 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41271</guid></item><item><title>Adaptive exercise-enabled model-predictive-control artificial pancreas control algorithm</title><caseId>2533</caseId><link>http://icoregon.technologypublisher.com/technology/41270</link><description><![CDATA[
Summary

Artificial pancreas devices help maintain healthy glucose levels in patients with type 1 diabetes (T1D), but incidences of hypoglycemia are still common after episodes of eating, sleeping and exercise.&nbsp; Oregon Health &amp; Science University researchers have developed an algorithm that features adaptive responses to these factors as well as individual variability, allowing for more personalized and accurate control of type 1 diabetes.

Technology Overview

Fluctuations in glucose and insulin sensitivity occur in a variety of situations, often making it necessary for individuals ...]]></description><pubDate>Thu, 13 Aug 2020 09:54:52 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41270</guid></item><item><title>Clickable, photoactivatable NAD+ analogues as probes for PARP and other NAD+-binding targets</title><caseId>2757</caseId><link>http://icoregon.technologypublisher.com/technology/41227</link><description>
Summary

Researchers at OHSU have developed a screening platform for identification of proteins regulated by PARPs, which relies on a novel bi-functional NAD analog containing a photo-reactive group for crosslinking to binding targets and a click tag for their identification. This tool can be used to efficiently screen cell lysates to uncover novel PARP biology for translational research.

Technology Overview

PARP enzymes regulate diverse cellular functions through a post-translational modification involving the transfer of ADP-ribose moiety from an NAD molecule to a targeted protein. PARP i...</description><pubDate>Fri, 07 Aug 2020 14:08:28 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41227</guid></item><item><title>Non-invasive imaging detection of tumor-associated macrophages in glioblastoma</title><caseId>2598</caseId><link>http://icoregon.technologypublisher.com/technology/41221</link><description>
Summary
Tracking immune responses in chemotherapy treated glioblastomas is important for interpreting disease progression, but current methods are invasive and require biopsies. OHSU researchers have developed an MRI-based method to detect tumor-associated macrophages to enable non-invasive monitoring of glioblastomas for research and surgical planning.

Technology Overview
Tumor-associated macrophages (TAMs) are a major constituent of the immune response to glioblastoma therapy, but assessing changes in this microenvironment is difficult and often requires invasive biopsies. OHSU researchers...</description><pubDate>Thu, 06 Aug 2020 16:36:35 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41221</guid></item><item><title>Collaborative workstation on wheels</title><caseId>2765</caseId><link>http://icoregon.technologypublisher.com/technology/41217</link><description>
Summary

Medical rounds are designed to increase communication between medical teams and improve patient care; however, errors in the electronic health record (EHR) are common and dangerous. Researchers at OHSU have designed a mobile computer on wheels device, consisting of three workstations in a triangular formulation, that provides collaborative and synchronous viewing of EHRs to increase rounds efficiency and reduce errors.

Technology Overview

Errors in patient electronic health records (EHR) can occur when there is a large volume of data and poor communication between inter-professiona...</description><pubDate>Thu, 06 Aug 2020 11:00:54 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41217</guid></item><item><title>Method of producing human pluripotent stem cells by somatic cell nuclear transfer</title><caseId>1838</caseId><link>http://icoregon.technologypublisher.com/technology/41211</link><description><![CDATA[
Summary

This is a method for producing patient-matched histocompatible pluripotent stem cells (PSC&rsquo;s) by somatic cell nuclear transfer (SCNT). 

Technology Overview

Pluripotent stem cells only naturally exist in early human embryos.&nbsp; The current methods produce experimental pluripotent stem cells (PSC&rsquo;s) using the patient&rsquo;s own skin cells as a starting point. Human PSC&rsquo;s derived by SCNT are histocompatible to a patient who provide skin cells, while conventional embryonic stem cells (ESC&rsquo;s) are isogenic. Furthermore, PSC&rsquo;s derived by SCNT have the sam...]]></description><pubDate>Wed, 05 Aug 2020 13:40:13 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/41211</guid></item><item><title><![CDATA[Feature Extraction & Segmentation]]></title><caseId>OSU-19-48</caseId><link>http://icoregon.technologypublisher.com/technology/41031</link><description>Technology Description

A common task in systems that utilize LiDAR data is the extraction of useful features from the cloud of points that LiDAR systems produce. This task is vital, and Norvana offers an efficient solution to the problem of feature extraction and segmentation of point cloud data. Given a collection of LiDAR data with 1 million points Norvana can process it within a second. Furthermore, the Norvana system is autonomous. Many applications involving LiDAR currently require immense amounts of human power, this technology allows these processes to be automated. This has benefits f...</description><pubDate>Thu, 16 Jul 2020 09:19:56 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/41031</guid></item><item><title>LiDAR Trajectory Reconstruction</title><caseId>OSU-19-47</caseId><link>http://icoregon.technologypublisher.com/technology/41006</link><description>Technology Description

Mobile LiDAR systems are used in a variety of applications such as mapping and autonomous vehicles. A fundamental part of mobile systems is deriving the trajectory of the LiDAR unit as it is moving. Many LiDAR systems do not capture this data requiring it to be reconstructed. This method for trajectory reconstruction offers the ability to reconstruct the trajectory data from point cloud data alone. This is useful because the ability to reconstruct trajectories allows systems to do much more accurate feature extraction, segmentation, and classification. One can also use ...</description><pubDate>Wed, 15 Jul 2020 11:09:45 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/41006</guid></item><item><title>A fast and robust standard-deviation based method for bulk-motion compensation in phase-based functional OCT</title><caseId>2530</caseId><link>http://icoregon.technologypublisher.com/technology/40837</link><description><![CDATA[Summary
Motion compensation algorithms are needed to correct for artifacts in phase-based functional OCT imaging, but current solutions require trade-offs between processing speed and &nbsp;image quality. Research at OHSU has led to the development of a novel motion compensation algorithm that can be processed quickly without sacrificing image quality, potentially improving diagnostic interpretation of OCT angiography and doppler OCT results.

Technology Overview
Phase-based functional OCT imaging (i.e. Doppler OCT and OCT angiography) relies on the comparison of multiple scans for extraction ...]]></description><pubDate>Thu, 09 Jul 2020 11:08:06 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/40837</guid></item><item><title>CRISIS ventilator</title><caseId>2889</caseId><link>http://icoregon.technologypublisher.com/technology/40521</link><description><![CDATA[
Summary

Researchers at OHSU have designed a novel ventilator system that 1) can be produced quickly, 2) has minimal operational requirements allowing for use in disaster settings and field facilities, and 3) has the capacity to provide both standard and severe respiratory distress ventilation support.

Technology Overview

The COVID-19 pandemic revealed flaws in the stockpiling and distribution of ventilators, demonstrating a need for more rapidly available and inexpensive alternatives.&nbsp; In addition, less expensive ventilators that can be utilized with limited resources can be critical ...]]></description><pubDate>Tue, 30 Jun 2020 14:31:46 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/40521</guid></item><item><title>New Drugs for Treatment of Type 1 Diabetes</title><caseId>OSU-18-63</caseId><link>http://icoregon.technologypublisher.com/technology/40461</link><description>Background   
Type 1 diabetes (T1D) is a life-threatening autoimmune disease that usually appears in childhood without warning. Current treatment options involve the administration of various insulin analogs and auxiliary therapies. The global market for T1D treatment is over $25 billion and growing. T1D is caused by the immune-mediated destruction of insulin producing beta cells in the pancreas, which leads to an inability to regulate blood glucose levels. People with T1D depend on lifelong insulin injections and constant testing of blood glucose in order to survive. However even T1D patients...</description><pubDate>Tue, 23 Jun 2020 21:38:27 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/40461</guid></item><item><title>Substituted Phenols and Benzenes for Pharmaceuticals, Agrochemicals and Synthetic Materials</title><caseId>OSU-20-03</caseId><link>http://icoregon.technologypublisher.com/technology/40013</link><description>Technology Description

This technology licensing opportunity is for novel phenol and benzene compounds with any number of substituents and complete positional selectivity. Synthesis of the compounds is achieved by a new synthetic method. The method provides a one-step conversion of readily available starting materials to give phenols with complete regioselective control and in high chemical yield. The programmable nature of the reaction allows construction of non-canonical substitution patterns. Finally, conversion of the phenols to the corresponding benzenes allows synthesis of highly substi...</description><pubDate>Wed, 20 May 2020 23:06:40 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/40013</guid></item><item><title>DailyDose decision support algorithm to improve glycemic control</title><caseId>2704</caseId><link>http://icoregon.technologypublisher.com/technology/39739</link><description><![CDATA[Summary
The DailyDose algorithm provides an artificial intelligence decision support system for improved management of blood glucose in patients with type 1 diabetes using multiple daily injection therapy.

Technology Overview
Up to 40% of patients with type 1 diabetes use multiple daily injections of insulin to manage their condition; however, dosing regimens can be complicated by daily changes in insulin sensitivity due to factors like meals and exercise.&nbsp; Failure to dose insulin properly can result in diabetic ketoacidosis and hypoglycemia, which may lead to coma or death. While many s...]]></description><pubDate>Thu, 30 Apr 2020 13:14:16 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/39739</guid></item><item><title>Method of Producing Oleofurans</title><caseId>OSU-20-11</caseId><link>http://icoregon.technologypublisher.com/technology/39379</link><description><![CDATA[Technology Description

This technology is a method for making oleofurans which can be derived from biomass and used as precursors for high performance oleofuran-based surfactants. This method minimizes or eliminates the use of toxic and/or expensive reagents, such as trifluoroacetic acid, and produces a small number of bi-products. This process produces the oleofuran compounds with commercially useful overall yields at competitive costs by implementing a simple two step synthesis pathway from readily available precursors. 

Features &amp; Benefits


	Safe reagents (NO trifluoroacetic acid)
	S...]]></description><pubDate>Thu, 26 Mar 2020 08:56:56 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/39379</guid></item><item><title>PVP Bean, Dry Peruano 'Patron'</title><caseId>OSU-16-43</caseId><link>http://icoregon.technologypublisher.com/technology/39351</link><description><![CDATA[Technology Description

Oregon State University has developed a new cultivar of yellow seeded &lsquo;Peruano&rsquo; market class dry bean. &lsquo;Patron&rsquo; is an improvement over existing &lsquo;Peruano&rsquo; cultivars in that it possesses the gene resistance to bean common mosaic and bean common mosaic necrosis viruses, and bct for resistance to beet curly top virus. These resistances are essential for production of dry beans in the intermountain western U.S. &lsquo;Patron&rsquo; has seed color similar to &lsquo;Peruano 87&rsquo;, similar maturities, with higher yields. This cultivar is ...]]></description><pubDate>Fri, 20 Mar 2020 10:18:48 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/39351</guid></item><item><title>Thermal Fan</title><caseId>OSU-19-75</caseId><link>http://icoregon.technologypublisher.com/technology/39064</link><description>Technology Description

This thermal fan device operates, in principle, similarly to a heat pipe by utilizing the latent heats of vaporization and condensation with the corresponding phase changes to move a fluid like air. A phase change working fluid is contained within a confined volume that is exposed to the low-grade heat. The working fluid is selected with a vaporization temperature compatible with the high temperature of the low-grade heat source. A compliant or flexible bellow is contained within that otherwise rigid volume, and pressure change resulting from the phase change of the wor...</description><pubDate>Wed, 04 Mar 2020 11:55:27 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/39064</guid></item><item><title>Electrocaloric Device</title><caseId>OSU-14-23</caseId><link>http://icoregon.technologypublisher.com/technology/39054</link><description>Technology Description

This technology is an electrocaloric devices as well as methods of making electrocaloric integrated circuits, and methods of thermally cycling integrated circuits. The electrocaloric device can include an electrocaloric material having a solid solution of two or more components of perovskites BNT, BKT, BZT, BMgT, or BNiT. The electrocaloric material can have an ergodic transition temperature within a range of 50 C to 300 C. The device can also include electrodes associated with the electrocaloric material, as well as an electrical source to add or reduce electrical fiel...</description><pubDate>Tue, 03 Mar 2020 12:11:14 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/39054</guid></item><item><title>Gonorrhea Subunit Vaccine</title><caseId>OSU-19-33</caseId><link>http://icoregon.technologypublisher.com/technology/38376</link><description>Background of Invention

Each year witnesses roughly 78 million new gonorrhea infections [etiologic agent Neisseria gonorrhoeae (Ng)] worldwide. While often asymptomatic (particularly in females), untreated infection can lead to pelvic inflammatory disease, ectopic pregnancy, infertility, and increased transmission/acquisition of HIV. Although antimicrobials have been the standard treatment for gonorrhea, Ng has developed resistance to all antimicrobials used in empiric treatment. WHO, CDC, other public health organizations, and researchers have raised an urgent call for an effective gonorrhea...</description><pubDate>Thu, 30 Jan 2020 15:58:41 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/38376</guid></item><item><title>Fluorescence microscope for high resolution imaging and single-molecule tracking</title><caseId>2330</caseId><link>http://icoregon.technologypublisher.com/technology/38368</link><description>
Summary

Super-resolution microscopy and single-molecule tracking are powerful tools for biological research, but multicolor experiments have been difficult due to spectral crosstalk between fluorophores. Scientists at OHSU have developed a simple-to-use multispectral super-resolution microscope (MSSRM) system, compatible with live- or fixed-cell imaging that allows high precision imaging of biological samples with 10-20 colors at once.

Technology Overview

An important caveat of super-resolution microscopy is color cross-talk, which greatly limits the maximum number of fluorophores that can...</description><pubDate>Thu, 30 Jan 2020 11:01:43 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/38368</guid></item><item><title>Treatment for Hypertension</title><caseId>OSU-14-47</caseId><link>http://icoregon.technologypublisher.com/technology/37684</link><description><![CDATA[Technology Description &nbsp;This technology opportunity provides antisense oligomer compounds and methods for the treatment of hypertension that overcome the various limitations and drawbacks associated with the use of substrate inhibitors. The compounds accumulate in the kidney, which allows for efficient dosing, and can be developed for transdermal, subcutaneous, or oral administration. In certain embodiments, the compound may be especially effective in addressing the unmet medical needs relating to hypertension in the African American population. In addition, this technology provides an op...]]></description><pubDate>Tue, 07 Jan 2020 16:30:30 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/37684</guid></item><item><title>In-Situ Bioremediation with Slow Release Co-metabolism Substrates</title><caseId>OSU-18-70</caseId><link>http://icoregon.technologypublisher.com/technology/37248</link><description>Background of Invention

A variety of highly toxic contaminants of concern persist in soils and groundwater at industrial sites across the country. Treatment, if even feasible, is often very expensive and time consuming. In-situ bioremediation of multiple contaminants with slow release cometabolism allows is attractive, but faces challenges of substrate limitations, slow kinetics, and the prolonged viability of the microorganisms carrying out the remediation. There is a need for technologies that can better sustain the bioremediation process by localizing and retaining the microorganisms in th...</description><pubDate>Tue, 26 Nov 2019 11:11:12 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/37248</guid></item><item><title>Thermally Actuated Freshwater Recovery System for Fracking Wastewater</title><caseId>OSU-19-21</caseId><link>http://icoregon.technologypublisher.com/technology/37247</link><description>Technology Description

This technology, a product of Oregon State University research, details a device for the efficient treatment of wastewater produced from hydraulic fracturing (fracking). Relying upon the properties of water azeotropes and humid gas thermodynamics, this system is capable of treating water with a wide range and high concentration of contaminants without excessive energy consumption or the solute buildup associated with membrane systems. Unique engineering processes surrounding airflow velocity and centrifugal forces allow for the precise control of flow parameters necessa...</description><pubDate>Tue, 26 Nov 2019 10:58:20 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/37247</guid></item><item><title>High Flux Resistance Heating Rod</title><caseId>OSU-19-12</caseId><link>http://icoregon.technologypublisher.com/technology/37240</link><description>A high flux, small diameter heating rod capable of producing 2.5MW/m2 in a matter of tens of milliseconds 

Background   
With the renewed emphasis on the development of advanced reactor technologies, there is an interest in assessing the performance of materials under both normal operating conditions and during hypothesized incident scenarios. Use of nuclear test facilities can be prohibitively expensive and difficult to schedule. The ability to stress materials in a dynamic facility, with operating conditions similar to those of a nuclear reactor, without radiological concerns, is of great b...</description><pubDate>Fri, 22 Nov 2019 15:12:58 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/37240</guid></item><item><title>Aqueous solution precursors for conductive oxide thin films</title><caseId>OSU-18-74</caseId><link>http://icoregon.technologypublisher.com/technology/37239</link><description>Technology Description

Inventors at OSU have developed a method for creating conductive oxide thin films from aqueous precursor solutions that have high density, low surface roughness, high optical transmissivity, and good electronic properties. This solution processing method of preparing the conductive oxide thin films has a lower energy cost than conventional deposition techniques that utilize vacuum and higher temperature anneals. These formulations of high-purity metal oxides are promising materials that can provide performance advantages in a variety of applications, including: Solar pa...</description><pubDate>Fri, 22 Nov 2019 14:46:55 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/37239</guid></item><item><title>Apparatus for Water Desalination</title><caseId>OSU-17-65</caseId><link>http://icoregon.technologypublisher.com/technology/37238</link><description><![CDATA[Technology Description

This technology is a device that can utilize low-grade heat for efficient desalination with minimal fouling. It achieves zero liquid discharge through its utilization of high velocity gases and gas-solid separators to atomize highly saline water. The technology is modular, portable, and is running-cost competitive with large reverse osmosis desalination plants at a fraction of the overhead capital cost. The process is energy efficient and can utilize a wide variety of low-grade heat sources, including solar thermal and waste industrial heat. 

Features &amp; Benefits


...]]></description><pubDate>Fri, 22 Nov 2019 12:54:33 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/37238</guid></item><item><title>Novel agents for the detection and treatment of bladder cancer</title><caseId>2779</caseId><link>http://icoregon.technologypublisher.com/technology/35916</link><description><![CDATA[
Summary

Given the prevalence of bladder cancer in the United States, it is surprising that a limited number of treatments exist for this disease.&nbsp; To address this unmet need, researchers at Oregon Health &amp; Science University have developed novel agents for use in both detecting and treating early stage, non-invasive bladder cancer.&nbsp; 

Technology Overview

About half of all bladder cancers are identified early, when they are in the non-invasive stage and are limited to the innermost layer of the bladder wall.&nbsp; Despite current treatment options, non-invasive bladder cancers ...]]></description><pubDate>Thu, 05 Sep 2019 17:20:18 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/35916</guid></item><item><title>Emerald Sprite Cotoneaster</title><caseId>OSU-18-59</caseId><link>http://icoregon.technologypublisher.com/technology/35529</link><description><![CDATA[Technology Description

Emerald Sprite&nbsp;(Cotoneaster x suecicus) is a new fire blight resistant cotoneaster cultivar with a highly compact, mounding habit, extremely dense foliage, and short internodes. It is novel for its combination of habit and improved disease resistance.

Features &amp; Benefits

The following traits have been repeatedly observed and are determined to be unique to Emerald Sprite. Collectively, these traits distinguish Emerald Sprite&nbsp;from other available cotoneasters.


	Highly compact growth form with a clumping growth habit, as opposed to the more standard creep...]]></description><pubDate>Tue, 20 Aug 2019 13:34:08 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35529</guid></item><item><title>Emerald Beauty</title><caseId>OSU-19-35</caseId><link>http://icoregon.technologypublisher.com/technology/35528</link><description><![CDATA[Technology Description

The new Cotoneaster plant is a result of a breeding program directed by the inventor at Oregon State University, Corvallis, OR (US) to develop new cultivars of cotoneasters that are resistant to fire blight caused by the pathogen Erwinia amylovora, are compact, and perform well in nursery production and landscapes.

Features &amp; Benefits
The following traits have been repeatedly observed and are determined to be unique to Emerald Beauty. Collectively, these traits distinguish Emerald Beauty from other available cotoneasters.


	Resistance to fire blight
	Excellent con...]]></description><pubDate>Tue, 20 Aug 2019 13:30:59 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35528</guid></item><item><title>Glucose prediction algorithm using long-short term memory recurrent neural network</title><caseId>2705</caseId><link>http://icoregon.technologypublisher.com/technology/35182</link><description>Summary
The OHSU glucose prediction algorithm is a data-driven glucose prediction model trained on a big dataset to predict glucose concentration within a short term (30 minute) period for patients with type 1 diabetes.

Technology Overview
Patients with type 1 diabetes do not produce their own insulin and rely on continuous glucose monitoring (CGM) systems and insulin pumps to help manage glucose levels. Accurate glucose prediction algorithms are critical components of CGM systems to help people proactively avoid adverse hyper- or hypo-glycemic events.

The OHSU glucose prediction algorithm i...</description><pubDate>Mon, 29 Jul 2019 10:21:54 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/35182</guid></item><item><title>Solution Deposition of Amorphous Zirconia Thin Films</title><caseId>OSU-18-68</caseId><link>http://icoregon.technologypublisher.com/technology/35067</link><description><![CDATA[Technology Description

OSU researchers have developed methods of making amorphous zirconium and hafnium halogenides with aqueous solution processing. The resulting films are extremely smooth, nearly as dense as fully densified crystalline films, and have high optical transparency. The solution deposition process eliminates the need for processing under a vacuum and enables coverage of large area substrates. The aqueous chemistry eliminates most hazardous and costly solvents and also reduces post-deposition processing.

Features &amp; Benefits


	Less expensive equipment costs
	High quality fi...]]></description><pubDate>Mon, 22 Jul 2019 13:05:38 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35067</guid></item><item><title>Solution Deposition of Transparent Conductive Oxide Thin Films</title><caseId>OSU-18-25</caseId><link>http://icoregon.technologypublisher.com/technology/35066</link><description><![CDATA[Technology Description

This technology is an aqueous solution deposition process for making high quality thin films of tin oxide, tin antimony oxide, and doped compositions of both. Films made by these methods are extremely smooth, highly transparent, and can be made at variable thicknesses from several nanometers up to a micron. The electrical and optical properties of these solution-deposited films are comparable or better than similar films deposited by sputtering.

Features &amp; Benefits


	Low capital costs
	Benign chemistries
	High quality films


Applications


	Solar panels and elect...]]></description><pubDate>Mon, 22 Jul 2019 12:40:23 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35066</guid></item><item><title>Extrusion System for 3D Printing of Silicone Elastomers</title><caseId>OSU-18-73</caseId><link>http://icoregon.technologypublisher.com/technology/35064</link><description>Novel 3D printing system enables rapid fabrication of complex structures from soft, multi-component silicone elastomers 

Background   
Conventional fabrication of an elastomeric component for soft robotic or actuator applications is laborious and time consuming. Many molding and casting techniques are also inconsistent and difficult to control. Additive manufacturing is an attractive alternative, but significant challenges remain in printing highly viscous materials into complex structures. To date, commercially available systems still cannot produce complex components while also achieving si...</description><pubDate>Mon, 22 Jul 2019 12:10:29 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35064</guid></item><item><title>Cu-based Bulk Metallic Glass Alloy</title><caseId>OSU-19-14</caseId><link>http://icoregon.technologypublisher.com/technology/35062</link><description>New production method to create amorphous alloys that possess superior mechanical properties compared to crystalline metals 

Background   
Conventional metals or alloys comprise numerous crystal grains and crystal-related defects such as grain boundaries, dislocations and vacancies/voids. Amorphous alloys, also known as metallic glasses, are free of crystal grains and crystal-related defects, and because of this, possess many properties far superior to conventional alloys. Examples of such properties are theoretical-limit approaching strength, high hardness, high elastic strain limit, and hig...</description><pubDate>Mon, 22 Jul 2019 11:06:01 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35062</guid></item><item><title>Self-Starting Thermoelectric Energy Harvester</title><caseId>OSU-19-19</caseId><link>http://icoregon.technologypublisher.com/technology/35061</link><description><![CDATA[An integrated circuit that can cold start a DC-DC boost converter on a very small input voltage 

Background   
Energy harvested from body heat using thermoelectric generators (TEG) can be used to power wearable electronics, such as wireless sensors. However, owing to the small temperature gradient between the skin surface and ambient air (&sim;1-2 ◦C) and a low Seebeck coefficient, centimeter-scale TEGs can generate only tens of millivolts of open circuit voltage. A DC-DC converter is needed to boost this voltage to &ge;1V for efficient operation of typical load electronics, like a sensor. Ty...]]></description><pubDate>Mon, 22 Jul 2019 09:26:21 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/35061</guid></item><item><title>Nanohoop Compounds as a Biotechnology Tool</title><caseId>UO-17-25</caseId><link>http://icoregon.technologypublisher.com/technology/34626</link><description><![CDATA[
1. Technology Overview&nbsp;

&nbsp;

The invention focuses on cycloparaphenylenes (CPPs), also known as&nbsp;nanohoops, which are being developed as new tools in biotechnology. These CPPs have unique fluorescent properties and can be functionalized for labeling, detection, and incorporation into biomolecules. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery.

&nbsp;

2. Key Features and Benefits&nbsp;


	
	Tunable Fluorescence: Provides high sensitivity for biological detection and im...]]></description><pubDate>Wed, 19 Jun 2019 13:21:19 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/34626</guid></item><item><title>Synthetic Cephalotaxine Synthesis and New Anti-Cancer Compounds</title><caseId>OSU-19-01</caseId><link>http://icoregon.technologypublisher.com/technology/34551</link><description><![CDATA[Technology Description

Oregon State University is seeking a licensee for an improved method to synthesize chemotherapeutic Homoharringtonine (HHT) that overcomes the need to use plant derived cephalotaxine. The synthetic method provides a high yield of chemically synthesized cephalotaxine as an HHT precursor and also enables the synthesis of novel analogues of cephalotaxine, as well as derivative compounds made from cephalotaxine and its analogues. These new compounds provide an opportunity for chemotherapeutic drug discovery and development. This work is published as: Total Synthesis of (&mi...]]></description><pubDate>Fri, 14 Jun 2019 09:19:36 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/34551</guid></item><item><title>Photoreactor for Treatment of Jaundice</title><caseId>OSU-14-27</caseId><link>http://icoregon.technologypublisher.com/technology/32439</link><description><![CDATA[&nbsp;Technology Description &nbsp;Oregon State University is seeking a licensee or research collaborator for development or commercialization of a microfluidic visible light photoreactor for the treatment of jaundice in neonatal patients. The device enables safe extracorporeal blood treatment, making it an excellent replacement for equally effective, yet risky, exchange transfusions while having a safety profile comparable to current phototherapy technologies. Designed components remove heat from the system, ensuring blood cell survival, and an LED light system reacts bilirubin to the nontoxi...]]></description><pubDate>Mon, 22 Apr 2019 14:48:43 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/32439</guid></item><item><title>THUNDER™ Barley (10.0777)</title><caseId>OSU-19-08</caseId><link>http://icoregon.technologypublisher.com/technology/31693</link><description><![CDATA[Technology Description &nbsp;THUNDER&trade; - a two-row winter, malting barley developed by Oregon State University (OSU) - has met AMBAs requirements and was selected for the 2019 recommendation list for malting barley&rsquo;s. &nbsp;THUNDER&trade; is higher yielding than Endeavor and equivalent to Wintmalt, considering all the available data: irrigated, dryland, and high rainfall. THUNDER&trade; and Endeavor are both seven days earlier to head than Wintmalt, an advantage for reducing the number of irrigations required and avoiding summer heat stress, which can reduce malting quality.&nbsp;Un...]]></description><pubDate>Wed, 13 Mar 2019 13:11:33 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/31693</guid></item><item><title>System to detect peripheral neuropathy, balance, and mobility disorders</title><caseId>2063</caseId><link>http://icoregon.technologypublisher.com/technology/31321</link><description><![CDATA[
Summary

A home test for peripheral neuropathy.

Technology Overview

For clinicians and patients who are dissatisfied with the battery of clinical tests for peripheral neuropathy, the PeriVib is a portable home system. The PeriVib comprises a toe vibration motor, a mobile application to measure balance and gait, and algorithms to evaluate the data.

The vibration motor applies a vibration stimulus to the toe with constant pressure to test sensation threshold. The mobile application controls and records the vibration amplitude when onset or loss of vibration sensation is indicated.&nbsp; Acce...]]></description><pubDate>Fri, 15 Feb 2019 09:37:15 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/31321</guid></item><item><title>Monoclonal antibody (10D4) against the β subunit of human epithelial sodium channel (hENaC)</title><caseId>2639-B</caseId><link>http://icoregon.technologypublisher.com/technology/31286</link><description><![CDATA[
Technology Overview
Monoclonal antibody (10D4) against the &beta; subunit of human epithelial sodium channel (hENaC). The antibody recognizes the tertiary, 3D epitope of the beta subunit and is characterized as IgG1 with a kappa light chain. It binds with high affinity and specificity to the respective subunits constituting hENaC.

Epithelial sodium channels (ENaC) are involved in regulating Na+ homeostasis. ENaCs primarily require three different subunits to form a functional channel, &alpha;, &beta; and &gamma;.

Potential uses include:


	purification of human ENaC for structure studies wi...]]></description><pubDate>Mon, 11 Feb 2019 11:09:56 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/31286</guid></item><item><title>Monoclonal antibody (7B1) against the α  subunit of human epithelial sodium channel (hENaC)</title><caseId>2639-A</caseId><link>http://icoregon.technologypublisher.com/technology/31285</link><description><![CDATA[
Technology Overview
Monoclonal antibody (7B1) against the &alpha; subunit of the human epithelial sodium channel (hENaC). The antibody recognizes the tertiary, 3D epitope of the alpha subunit and is characterized as IgG2 with a kappa light chain. It binds with high affinity and specificity to the respective subunits constituting hENaC.

Epithelial sodium channels (ENaC) are involved in regulating Na+ homeostasis. ENaCs primarily require three different subunits to form a functional channel, &alpha;, &beta; and &gamma;.

Potential uses include:


	purification of human ENaC for structure studi...]]></description><pubDate>Mon, 11 Feb 2019 11:08:40 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/31285</guid></item><item><title>A therapeutic approach to minimize residual disease and relapse in cancer</title><caseId>2413</caseId><link>http://icoregon.technologypublisher.com/technology/31128</link><description><![CDATA[
Technology Overview

OHSU researchers have identified a novel treatment method which, when used in combination with first-line cancer therapies, has the potential to minimize residual disease, the primary cause of relapse in all cancers.&nbsp; The method leverages existing drugs that inhibit a metabolic target molecule not previously understood to be involved in autophagy, a biological mechanism that supports tumor cell survival.&nbsp; Inhibition of this target, combined with standard therapy, can be used to treat cancers more effectively.

&nbsp;

Licensing Opportunity

This technology is av...]]></description><pubDate>Fri, 18 Jan 2019 12:05:37 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/31128</guid></item><item><title>Adipose-specific fluorescent dyes for in vivo imaging</title><caseId>2579</caseId><link>http://icoregon.technologypublisher.com/technology/30408</link><description><![CDATA[
Summary

Researchers at Oregon Health &amp; Science University have developed novel adipose-specific fluorescent dyes for use in image-guided surgery of anatomical structures, such as nerves, that are surrounded by adipose tissue. The generated fluorophores exhibit reduced nerve accumulation, and demonstrate higher adipose-to-nerve and adipose-to-muscle contrast than existing adipose-selective dyes.&nbsp; 

Technology Overview

The identification of normal and diseased tissues during surgical procedures is largely dependent upon a surgeon&rsquo;s experience and skill level.&nbsp; However, sur...]]></description><pubDate>Fri, 04 Jan 2019 15:48:41 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/30408</guid></item><item><title>Microfluidic device for blood plasma separation and assays</title><caseId>OSU-17-62</caseId><link>http://icoregon.technologypublisher.com/technology/30035</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking a licensee for a microfluidic device that separates blood plasma from whole blood and can facilitate downstream assays. The device can be used with raw blood or blood treated with anticoagulants, both with a lower volume than is required by current testing strategies. Testing zones of different chemistries and assays can be integrated downstream of the plasma separation zone for point of care diagnostics and target analysis of blood plasma constituents. Composed of a simple membrane-based wicking microfluidic device fabricated on ...]]></description><pubDate>Wed, 05 Dec 2018 09:41:01 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/30035</guid></item><item><title>Improved KNN Thin Film Production</title><caseId>OSU-18-18</caseId><link>http://icoregon.technologypublisher.com/technology/29893</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking a licensee or industry collaborator for an improved KNN based thin film production process. The newly described methods overcome the difficulties in chemical vapor, sol-gel, sputtering, and pulsed-laser deposition methods because it can be performed cost effectively, in air, using less energy, and with the scalability that standard production methods lack. In addition to these advantages, the thin films produced by this method have superior properties in degree of orientation and surface roughness, allowing the film to be aligned ...]]></description><pubDate>Fri, 30 Nov 2018 15:58:29 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/29893</guid></item><item><title>Virtual patient population for mathematical representation of glucose metabolism in type 1 diabetes</title><caseId>2532</caseId><link>http://icoregon.technologypublisher.com/technology/29844</link><description><![CDATA[
Summary

A method for&nbsp;in silico&nbsp;validation and development of devices and algorithms for glucose management, such as insulin pumps. 

Technology Overview

This is a mathematical model of the glucoregulatory system.&nbsp; It is comprised of a set of differential equations that represent compartments in the human body through which glucose is metabolized.&nbsp; The inputs to the model are carbohydrates, exercise, insulin, and glucagon.&nbsp; The output of the model is plasma glucose.&nbsp; From this, a person&rsquo;s plasma glucose level can be estimated based on food intake as well a...]]></description><pubDate>Tue, 27 Nov 2018 10:26:38 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/29844</guid></item><item><title>Hazelnut named ‘PollyO’ Well-Suited for the Blanched Kernel Market for Use in Chocolate Products and Baked Goods</title><caseId>OSU-18-06</caseId><link>http://icoregon.technologypublisher.com/technology/28905</link><description><![CDATA[Technology Description &nbsp;&lsquo;PollyO&rsquo; is being released for the blanched kernel market as a companion for &lsquo;Wepster&rsquo; and &lsquo;McDonald&rsquo;, and as an alternative to &lsquo;Yamhill&rsquo;. The nut shape is nearly round and lends itself well to sizing and cracking. The shells are thin and easy to crack, and most kernels remain whole when the shell is broken. Kernel size is small, similar to &lsquo;McDonald&rsquo; but larger than &lsquo;Wepster&rsquo; and &lsquo;Yamhill&rsquo;.&nbsp;Features &amp; Benefits 'PollyO' is cross-compatible with &lsquo;Wepster&rsquo; and &ls...]]></description><pubDate>Mon, 01 Oct 2018 12:19:18 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/28905</guid></item><item><title>iPancreas: Internet based on-demand  artificial pancreas app-generator to accelerate clinical trials research</title><caseId>2576</caseId><link>http://icoregon.technologypublisher.com/technology/28647</link><description><![CDATA[
Technology Overview

The iPancreas software will enable researchers to rapidly develop a custom artificial pancreas (i.e. automated delivery of insulin and glucagon in response to sensed glucose) smart phone app utilizing their own artificial pancreas control algorithms and user interfaces. The OHSU software is capable of generating an app that can run on a smart phone and execute the functionality of an artificial pancreas.&nbsp; Use of the iPancreas software will allow researchers to develop a customized application for their own specific uses.

Licensing Opportunity

This technology is ava...]]></description><pubDate>Fri, 31 Aug 2018 11:06:16 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/28647</guid></item><item><title>System to measure sleep apnea using portable non-contact sensors and a machine learning algorithm</title><caseId>2595</caseId><link>http://icoregon.technologypublisher.com/technology/28646</link><description>
Summary

Method and system for automatic diagnosis of sleep apnea in the home environment. The system uses pressure sensitive sensors placed underneath a mattress and an algorithm to classify the severity of sleep apnea.

Technology Overview

This in-home system to diagnose sleep apnea saves the patient from having to spend a night in a sleep clinic attached to numerous sensors and wires. In the comfort of their own home, patients will put a rectangular metal plate with attached load cell sensors under their mattress. During the course of the night, these sensors record respiration rate, brea...</description><pubDate>Fri, 31 Aug 2018 10:14:49 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/28646</guid></item><item><title>PE Conjugated HPa3 Monoclonal Antibody Supernatant from Hybridoma HIC3-2D12 (alpha/delta/gamma/epsilon cell marker)</title><caseId>1873-A1</caseId><link>http://icoregon.technologypublisher.com/technology/28434</link><description><![CDATA[Technology Overview
PE conjugated version of the monoclonal antibody HPa3, derived from the hybridoma HIC3-3D12.&nbsp; HPa3 does not label beta cells, labels delta cells dimly, and brightly labels alpha, gamma, and epsilon cells in human pancreatic islets.

Publication
Dorrell C, et al. Human islets contain four distinct subtypes of beta cells. Nat Commun. 2016 Jul 11;7:11756. Link]]></description><pubDate>Thu, 09 Aug 2018 11:03:31 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/28434</guid></item><item><title>HPa3 Monoclonal Antibody Supernatant from Hybridoma HIC3-2D12 (alpha/delta/gamma/epsilon cell marker)</title><caseId>1873-A</caseId><link>http://icoregon.technologypublisher.com/technology/27787</link><description><![CDATA[
Technology Overview
The monoclonal antibody HPa3 is derived from the hybridoma HIC3-3D12.&nbsp; HPa3 does not label beta cells, labels delta cells dimly, and brightly labels alpha, gamma, and epsilon cells in human pancreatic islets.

&nbsp;

Isotype: Mouse IgM

&nbsp;

Publications 
Dorrell C, et al. Human islets contain four distinct subtypes of beta cells. Nat Commun. 2016 Jul 11;7:11756. Link

&nbsp;]]></description><pubDate>Thu, 31 May 2018 15:04:28 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/27787</guid></item><item><title>An Apparatus and Process For Optimizing Radiation Detection Counting Times Using Machine Learning</title><caseId>OSU-17-70</caseId><link>http://icoregon.technologypublisher.com/technology/27743</link><description><![CDATA[Technology Description &nbsp;This algorithm is applicable to radiation detection and counting, for example, in Gamma spectroscopy. The purpose of this algorithm is to eliminate the need for a priori information when counting radioactive material and instead using machine learning techniques to solve the optimal counting time real-time. Data are arranged into a matrix, which can then be used to create training material for classification. Once the desired outcome is achieved (i.e., radiation source is identified, radiation dose reaches a specific threshold, or the radiation applied suffices to ...]]></description><pubDate>Mon, 21 May 2018 14:40:12 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27743</guid></item><item><title>Mycobacterium Bovis Vaccine to Prevent Bovine Tuberculosis</title><caseId>OSU-17-19</caseId><link>http://icoregon.technologypublisher.com/technology/27709</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking a licensee or collaborative research partner to develop a Mycobacterium bovis vaccine for the prevention of bovine tuberculosis. The vaccine is based on the discovery of bacterial surface antigens expressed during an infection. These surface antigens are present on bacteria transmitted from an infected host to an uninfected one. Work done in a mouse model of infection demonstrates the IgA response is superior (statistically significant) when the antigens are delivered into the airway, compared with intradermal immunization.&nbsp;F...]]></description><pubDate>Tue, 15 May 2018 15:27:29 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27709</guid></item><item><title>Pressure Pass-Through Strain Sensor</title><caseId>OSU-17-63</caseId><link>http://icoregon.technologypublisher.com/technology/27696</link><description>A pressure pass-through apparatus for a distributed strain sensor, providing a very economical solution to pass optical fibers 

Background   
Currently, there are a large number of measurement techniques that utilize fiber-optical means, the use of light to acquire measurement. However, these measurement techniques have limitations on how effective they are in certain state conditions of the environment. The current solutions are not reliable in cases when a signal needs to be transmitted between non-ambient (high pressure, high temperature, corrosive, etc.) environments and ambient environme...</description><pubDate>Fri, 11 May 2018 14:23:54 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27696</guid></item><item><title>Plant Protective Coating</title><caseId>OSU-17-40</caseId><link>http://icoregon.technologypublisher.com/technology/27647</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking a licensee or research collaborator interested in developing and commercializing new plant protective coatings that supplement a plant&rsquo;s natural protective cuticle. Application of the coating to fruit can prevent or reduce cracking, sunburn, and insect damage. In certain applications, the coatings also increase fruit size and extend the shelf life of post-harvest fruit.&nbsp;Features &amp; Benefits &nbsp;Protective cuticle supplement for reduced water loss and water usageIncreased fruit sizeReduced fruit damage&nbsp;Applicat...]]></description><pubDate>Wed, 02 May 2018 16:13:47 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27647</guid></item><item><title>Wind turbine sensor array for monitoring avian and bat collisions v2.0</title><caseId>OSU-18-17</caseId><link>http://icoregon.technologypublisher.com/technology/27296</link><description><![CDATA[Technology Description &nbsp;An integrated multi-sensor detection package with event-based data collection has been developed using accelerometers, microphones, and a camera coupled with integrated signal processing. The sensors are installed directly on wind turbine blades and on-board processors wirelessly transmit data to the central controller and data acquisition system immediately after a collision. The accelerometers and contact microphones provide continuous temporal coverage for collision detection. The visual and IR cameras and bioacoustic recorders provide taxonomic classification. ...]]></description><pubDate>Mon, 12 Mar 2018 14:16:14 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27296</guid></item><item><title>Low-Power Remote Logging Weight and Temperature Sensor</title><caseId>OSU-16-64</caseId><link>http://icoregon.technologypublisher.com/technology/27133</link><description><![CDATA[Technology Description &nbsp;The sensor includes a load cell, external temperature sensor, logger, and fuel container. The inexpensive monitor provides an easy launch via simple switch, data collection via SD card for ease of processing, a flexible power supply to last for any desired duration, and a cloud-based analysis platform to indicate the variability and post-processing parameters of interest. This information can provide the needed and currently unavailable robust indicators of programmatic success in terms of user technology uptake and resulting fuel and time savings at a low cost and...]]></description><pubDate>Thu, 15 Feb 2018 14:13:15 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27133</guid></item><item><title>Treatment for Muscle Atrophy and for Enhancing Muscle Growth</title><caseId>OSU-16-44</caseId><link>http://icoregon.technologypublisher.com/technology/27049</link><description>An mRNA based therapeutic that provides for increased hepatic production of follistatin 

Background   
Muscle atrophy is a detrimental and often severely debilitating disease state whose etiology lies within a myriad of disease states ranging from AIDS, sepsis, cardiac failure, muscular dystrophies, cancer, and the natural process of aging. The extent to which the atrophy is occurring can be a clear prognostic indicator of patient recovery and survival. Furthermore, the ability to maintain healthy lean muscle mass whether through exercise or other therapeutic interventions is crucial for the ...</description><pubDate>Thu, 01 Feb 2018 09:01:05 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/27049</guid></item><item><title>Paper-based Microfluidic Well Plates</title><caseId>OSU-17-17</caseId><link>http://icoregon.technologypublisher.com/technology/26732</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking a licensee for a paper-based microfluidic well plate systems that are cheaper, modifiable replacements for plastic well plate systems currently in use. This technology has been tested in a 96-well plate embodiment for analysis of a panel of disease biomarkers, environmental and health toxins, and indicators of wellness. The technology is low-cost, disposable, safer due to limited reagent handling, compatible with existing 96-well plate technologies, and reduces current multi-step assays into just one step. The device is simple, bi...]]></description><pubDate>Fri, 15 Dec 2017 10:38:23 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/26732</guid></item><item><title>Algorithm For Automated Detection of Melanoma</title><caseId>1444</caseId><link>http://icoregon.technologypublisher.com/technology/26571</link><description><![CDATA[
Summary

Incidence of malignant melanoma (MM) are increasing in the United States, and early
detection and excision are critical due to the high tendency for MMs to metastasize. Oregon Health &amp; Science University researchers have developed an automated cellular quantification software for use with reflectance confocal microscopy that could increase the efficiency and accuracy of MM diagnosis as well as identify premature signs of aging. 

Technology Overview

Comprehensive diagnosis of MM typically requires both reliable histopathology and the trained eye of a clinician for assessment, bu...]]></description><pubDate>Thu, 09 Nov 2017 08:02:07 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/26571</guid></item><item><title>Jejunal/enteral tube fixation and locking device</title><caseId>2365</caseId><link>http://icoregon.technologypublisher.com/technology/26542</link><description>
Summary

A fastener device with a novel locking mechanism to attach jejunal/enteral feeding tubes in gastrointestinal surgery. 

Technology Overview

Products currently used by surgeons comprise 4 independent T-fasteners to fix a segment of bowel to the inside of the abdominal wall. A flexible feeding tube is then inserted through the abdominal wall and attached via the fasteners. Problems occur when the fasteners break necessitating surgical intervention, as well as increased pain and skin infections.

The current product consolidates the alignment of the 4 fasteners in a novel housing assem...</description><pubDate>Mon, 06 Nov 2017 09:22:57 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/26542</guid></item><item><title>CRISPR/Cas9-targeted correction of heterozygous mutations in human preimplantation embryos</title><caseId>2391</caseId><link>http://icoregon.technologypublisher.com/technology/25855</link><description><![CDATA[
Technology Overview

More than 10,000 monogenic inherited disorders have been identified, affecting millions of people worldwide. Among these are the autosomal dominant mutations, where inheritance of a single copy of a defective gene can result in clinical symptoms. Dominant mutations that manifest as late-onset adult disorders include BRCA1 and BRCA2, associated with a high risk of breast and ovarian cancers and MYBPC3 causing hypertrophic cardiomyopathy (HCM).&nbsp; OHSU has a proprietary method to correct a mutant allele of a gene of interest in an embryo allowing homology-directed repair...]]></description><pubDate>Fri, 04 Aug 2017 16:30:43 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/25855</guid></item><item><title>High-Anthocyanin “Indigo™ Kiwi” Tomato</title><caseId>OSU-17-29</caseId><link>http://icoregon.technologypublisher.com/technology/25798</link><description><![CDATA[Technology Description &nbsp;Oregon State University has developed a new cultivar of tomato &ldquo;Indigo&trade; Kiwi&rdquo;, a type added to the small fruited Indigo high anthocyanin tomato series. These cultivars are primarily intended for the home garden and fresh market production. This new cultivar exhibits improvements in maturity, growth habit; flavor and leaf curl over the other Indigo&trade; tomato cultivars. Indigo&trade; Kiwi remains green when ripe with the fruit softening and becoming slightly lighter yellow in color. It is recommended that for commercial fresh market growers the ...]]></description><pubDate>Mon, 31 Jul 2017 14:55:37 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25798</guid></item><item><title>Mouse Model for Vitamin D Regulated Antimicrobial Peptide Expression</title><caseId>OSU-16-28</caseId><link>http://icoregon.technologypublisher.com/technology/25608</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking collaborative research opportunities or licensees for a humanized mouse model for vitamin D regulated antimicrobial peptide expression. The developed animal model is a transgenic mouse that carries a 6.2 kb human genomic DNA that possess the cathelicidin antimicrobial peptide (CAMP) gene. Vitamin D regulates the expression of the CAMP gene in both immune and epithelial barrier cells. This occurs via toll-like receptor signaling that activates the vitamin D pathway. This mechanism may explain the ability of vitamin D to boost the i...]]></description><pubDate>Thu, 06 Jul 2017 16:14:29 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25608</guid></item><item><title>A method to increase pregnancy rates for treatment of infertility</title><caseId>2347</caseId><link>http://icoregon.technologypublisher.com/technology/25538</link><description><![CDATA[
Summary

A method of generating functional human oocytes from polar bodies, which could be utilized to increase viable oocyte retrieval and prevent transmission of inherited mitochondrial DNA mutations.

Technology Overview

Because of the trend toward delayed childbearing in the Western world, the age-related infertility, embryonic and fetal loss, as well as birth defects are common. The efficacy of assisted reproductive technologies is limited by the number and quality of available oocytes calling for the development of additional sources of competent, patient-related oocytes.&nbsp; &nbsp; ...]]></description><pubDate>Thu, 22 Jun 2017 16:31:16 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/25538</guid></item><item><title>In vitro fertilization: Spindle transfer method for mitochondrial DNA replacement to circumvent genetically inherited genetic disorders</title><caseId>1376</caseId><link>http://icoregon.technologypublisher.com/technology/25537</link><description><![CDATA[
Summary

The current technology is method of preventing mitochondrial DNA disease transmission through oocyte spindle transfer. 

Technology Overview

Mitochondria, cytoplasmic organelles containing their own DNA (mtDNA), are crucial for the cell as they supply the cell with the majority of energy needed for basic cellular functions. mtDNA is transmitted maternally and normally all its copies are identical within the cell unless mutations in mtDNA occur resulting in the co-existence of normal and mutated mtDNA. Mutations in mtDNA occur at a 10 &ndash;fold or higher rate than in nuclear DNA an...]]></description><pubDate>Thu, 22 Jun 2017 16:18:26 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/25537</guid></item><item><title>Shared Antenna Interface for Simultaneous Transmit and Receive</title><caseId>OSU-17-23</caseId><link>http://icoregon.technologypublisher.com/technology/25532</link><description><![CDATA[Technology Description &nbsp;This technology describes a shared antenna interface for rejecting or passing transmitter and receiver signals. The interface can function up to RF frequencies of interest to cellular and WiFi wireless communications. The architecture is made using discrete or integrated circuits and builds upon N-class circuits where multiple switches are connected to the input enabling very selective filtering at high frequencies. The control signals applied to the switches are such that a certain impedance is presented at the thru and coupled ports for signals that have a certai...]]></description><pubDate>Wed, 21 Jun 2017 15:49:48 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25532</guid></item><item><title>RF Receiver with Interference Rejection</title><caseId>OSU-17-27</caseId><link>http://icoregon.technologypublisher.com/technology/25530</link><description><![CDATA[Technology Description &nbsp;This technology provides a scalable and reconfigurable receiver architecture for receiving code modulated signals at the receiver. Multiple switches operate at RF frequency, creating a n-path receiver that selects desired code for reception while rejecting others. This can improve performance of a receiver by enabling it to tolerate higher power interferers.&nbsp;Features &amp; Benefits &nbsp;Reduced interferenceReduced power consumption Improved spectrum utilization &nbsp;Applications&nbsp;Wireless networks Maritime vessels Defense and security &nbsp;Background of...]]></description><pubDate>Wed, 21 Jun 2017 15:42:52 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25530</guid></item><item><title>MicroRNA inhibitors to enhance radiotherapy efficacy</title><caseId>2414</caseId><link>http://icoregon.technologypublisher.com/technology/25501</link><description><![CDATA[
Summary

A method of enhancing radiotherapy efficacy through microRNA inhibition.

Technology Overview

Almost 50% of cancer patients undergo some form of radiotherapy; however only half of these patients have a significant response to this treatment. Higher doses of radiation can be effective, but often result in damage to nearby healthy organs.&nbsp; One approach to increase radiotherapy sensitivity of the targeted tissue is to enhance the efficacy of lower/normal dose radiation. This is particularly critical for cancers that respond well to radiation, but where toxicity may limit the use o...]]></description><pubDate>Thu, 15 Jun 2017 13:47:30 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/25501</guid></item><item><title>RNA biomarkers for predicting radiotherapy effectiveness</title><caseId>2359</caseId><link>http://icoregon.technologypublisher.com/technology/25500</link><description><![CDATA[
Summary

RNA signature that can differentiate between colorectal cancer patients having a partial or no response to radiation therapy. This signature can also be used as a biomarker to predict which patients will respond to standard-of-care radiation therapy, enabling the clinical management of the non-responding patient to encompass alternative neoadjuvant therapy.

Technology Overview

The standard of care for patients with a diagnosis of colorectal cancer is radiation therapy to reduce tumor size, followed by surgery.&nbsp; However, colorectal cancer patients do not respond equally to radi...]]></description><pubDate>Thu, 15 Jun 2017 13:35:05 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/25500</guid></item><item><title>Peptide Inhibitors of Gonorrhoeae</title><caseId>OSU-16-52</caseId><link>http://icoregon.technologypublisher.com/technology/25453</link><description><![CDATA[Technology Description &nbsp;Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal infections. In nitrite consumption assays carried out with two separate peptides, 90-50% inhibition of nitrite reductase activity was observed at concentrations of 0.6 and 0.3 mM, respectively. Work conducted to-date demonstrates the pep...]]></description><pubDate>Thu, 08 Jun 2017 08:08:08 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25453</guid></item><item><title>Monoclonal antibodies against the rat GluA2 AMPA receptor (14B11 and 15F1)</title><caseId>1671</caseId><link>http://icoregon.technologypublisher.com/technology/25219</link><description><![CDATA[
Technology Overview

The 14B11 and 15F1 antibodies are mouse-derived monoclonal antibodies that bind with high affinity and specificity to the rat GluA2 AMPA receptor.&nbsp; They are exceptional reagents for labeling the intact receptor under native (biological) conditions and can be used for a wide variety of imaging applications. They are not useful, however, for Western blotting, because they recognize 3 dimensional epitopes on the folded, intact receptor.&nbsp; 

Publication

Giannone G, et al., Dynamic superresolution imaging of endogenous proteins on living cells at ultra-high density. ...]]></description><pubDate>Thu, 04 May 2017 13:51:34 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/25219</guid></item><item><title>Anti-cancer Compounds</title><caseId>OSU-16-62</caseId><link>http://icoregon.technologypublisher.com/technology/25062</link><description><![CDATA[&nbsp;Technology Description &nbsp;This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effective as Bcl-2 targeted therapeutics in cancers with high Bcl-2 expression.&nbsp;Features &amp; Benefits &nbsp;Established mechanism of action and proven in vivo efficacy both on primary and metastatic tumor growthPotential to derive addi...]]></description><pubDate>Mon, 10 Apr 2017 15:55:04 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25062</guid></item><item><title>T-Pile: Software for Modeling Torsional Loading of Deep Foundations</title><caseId>OSU-16-37</caseId><link>http://icoregon.technologypublisher.com/technology/25053</link><description><![CDATA[&nbsp;Technology Description &nbsp;This technology is a software tool using a finite difference method to solve the governing differential equations describing the behavior of a drilled shaft or driven pile subjected to torsional loads. This software is used to evaluate the torsional resistance and rotation response of drilled shafts or driven piles in complex multi-layered soils. Users can specify known information about the soil at various depths to accurately reflect soil characteristics. The model program is then validated with torsional loading test data.&nbsp;Features &amp; Benefits &nbs...]]></description><pubDate>Mon, 10 Apr 2017 13:41:04 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25053</guid></item><item><title>Conductive Metalorganic Framework Chemical Sensors</title><caseId>OSU-16-17</caseId><link>http://icoregon.technologypublisher.com/technology/25037</link><description><![CDATA[&nbsp;Technology Description &nbsp;This technology is a gas sensing device made of a highly oriented metal-organic framework (MOF) material on an oxide substrate. The MOF is also made conductive by the addition of a redox active molecule. The conductive MOF is made without using a gold substrate, and the method of assembling the MOF layers incorporating the redox active molecule improves sensitivity and stability in gas sensing applications.&nbsp;Features &amp; Benefits &nbsp;High conductivity and sensitivity Simple manufacturing with known materialsOxide substrate &nbsp;Applications&nbsp;Moni...]]></description><pubDate>Thu, 06 Apr 2017 12:04:20 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/25037</guid></item><item><title>A Method to Treat Alzheimer’s, Heart and Liver Diseases</title><caseId>OSU-15-64</caseId><link>http://icoregon.technologypublisher.com/technology/24977</link><description><![CDATA[&nbsp;Technology Description &nbsp;This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a lipophilic cation, triphenylphosphonium, to target these compounds to mitochondria.&nbsp;Features &amp; Benefits &nbsp; Glutathione and its analogs are coupled to a triphenylphosphonium molecule via a cleavable linker. Once inside mitocho...]]></description><pubDate>Tue, 28 Mar 2017 09:57:36 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/24977</guid></item><item><title>Dried blood spot collection device</title><caseId>1810</caseId><link>http://icoregon.technologypublisher.com/technology/24557</link><description><![CDATA[
Summary

The current technology is an easier-to-use dried blood spot sampling device for either qualitative or quantitative analysis.

Technology Overview

In current Dried Blood Spot (DBS) sampling, poor technique can result in uneven concentrations across the material, which may lead to errors in analysis and unusable samples.

&nbsp;Additionally, many DBS sampling approaches rely on patients and/or clinicians to perform multiple steps that may be cumbersome, or may require disposal of blood collection materials as hazardous waste.&nbsp; The current device is a self-contained, easy-to-use, ...]]></description><pubDate>Wed, 08 Mar 2017 08:48:39 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/24557</guid></item><item><title>Mouse Model for Insulin Resistance</title><caseId>OSU-15-51</caseId><link>http://icoregon.technologypublisher.com/technology/24162</link><description><![CDATA[&nbsp;Opportunity Description &nbsp;Oregon State University is SEEKING RESEARCH COLLABORATIONS or LICENSEES for pharmaceutical R&amp;D, or obesity and diabetes research, to exploit A NEW TYPE 2 DIABETES MOUSE MODEL. Created by Oregon State University professor Chrissa Kioussi, the mouse model is a SKELETAL MUSCLE SPECIFIC PITX2 NULL MOUSE. Development of the mouse model led to the discovery that the sequence specific transcription factor Pitx2 regulates glucose metabolism and has a direct impact on glycemic control of muscle function and all energy control systems. Skeletal muscle is a major o...]]></description><pubDate>Wed, 22 Feb 2017 08:41:12 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/24162</guid></item><item><title>Surgical sponges dectable by magnetic field</title><caseId>1710</caseId><link>http://icoregon.technologypublisher.com/technology/24161</link><description><![CDATA[The prevention of retained surgical instruments currently requires a significant amount of labor in the surgery suite.&nbsp; The current state of the art is to assign surgical nurses to count sponges and instruments, which can allow human error. This is particularly true during long surgeries or if surgical personnel change during surgery.&nbsp;  These errors can result in patient complications and liability costs.&nbsp;This surgical sponge is specially designed to be detected during surgery to reduce the risk of a Retained Surgical Instrument.&nbsp; The design of the closed metal loops within...]]></description><pubDate>Wed, 22 Feb 2017 08:36:43 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/24161</guid></item><item><title>Pomace Based Molded Pulp Products and Packaging</title><caseId>OSU-15-53</caseId><link>http://icoregon.technologypublisher.com/technology/24099</link><description><![CDATA[
&nbsp;

Technology Description

&nbsp;

This technology licensing opportunity relates to pomace based molded pulp products and packaging. Molded pulp is used as a protective packaging and in products such as floral containers, nursery pots, food trays, and beverage containers. It is commonly made using fiber from recycled newspaper and other wood based sources, but reduction in the availability of recycled newspaper has created a need for alternative fibers. Fruit pomace, the byproduct from fruit juice and concentrate processes, is a readily available alternative fiber source. Oregon State Un...]]></description><pubDate>Thu, 16 Feb 2017 14:34:20 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/24099</guid></item><item><title>A High Flux Solar Thermal Receiver</title><caseId>OSU-15-58</caseId><link>http://icoregon.technologypublisher.com/technology/24064</link><description><![CDATA[&nbsp;Technology Description &nbsp;The microchannel based solar receiver (MSR) uses a modular arrangement of microchannels in its design that enable the working fluid to be heated in a concentrating solar receiver. The MSR is made of nickel super alloy and designed with the microchannels operating in parallel, which allows a large amount of flux to be removed by the receiver operating at high temperature and pressure. A branching distribution is used to enable a larger number of short microchannels. Microscale pins are used to reduce the temperature difference between the receiver surface and ...]]></description><pubDate>Mon, 13 Feb 2017 16:56:54 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/24064</guid></item><item><title>Antimicrobial Surface Coating</title><caseId>OSU-05-38</caseId><link>http://icoregon.technologypublisher.com/technology/23994</link><description>Background of Invention   
Advances in biomaterials engineering have led to numerous successful technologies in the medical field and have improved the quality of life for millions of people. However, there are still problems with blood coagulation, fibrosis, and infections associated with currently available materials. Most materials used in medical devices are susceptible to bacterial adhesion, which is very hard to remove once the bacteria forms a biofilm. Therefore, to reduce the chances of a medical device becoming infected, it is critical to prevent biofilm formation. In order to solve t...</description><pubDate>Mon, 06 Feb 2017 16:18:52 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/23994</guid></item><item><title>Marine Probiotic</title><caseId>OSU-16-31</caseId><link>http://icoregon.technologypublisher.com/technology/23745</link><description><![CDATA[Technology Description &nbsp;A newly identified marine bacterium strain useful as an aquaculture probiotic. Preliminary inhibition assays demonstrate that full cell culture and cell-free culture supernatant of the probiotic are sufficient to inhibit growth of the following Vibrio species: V. coralliilyticus (oysters and corals), V. parahaemolyticus (seafood-borne disease, wound infections), V. ulnificius (seafood-borne disease, severe wound infections, septicemia), V. harveyi (opportunistic pathogen of corals and seahorses, and commercially important products like prawn, lobster, barramundi, s...]]></description><pubDate>Tue, 27 Dec 2016 14:08:25 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/23745</guid></item><item><title>Rabbit polyclonal antisera against the Leishmania mexicana metabolic enzymes PPDK, PEPCK, FBPase and PYK</title><caseId>2075</caseId><link>http://icoregon.technologypublisher.com/technology/23687</link><description><![CDATA[
Technology Overview

Rabbit polyclonal antisera against Leishmania mexicana metabolic enzymes:&nbsp;


	Pyruvate phosphate dikinase (PPDK)
	Phosphoenolpyruvate carboxykinase (PEPCK)
	Fructose 1,6-biphosphatase (FBPase) 
	Pyruvate kinase (PYK)&nbsp;


Publication

Rodriguez-Contreras D, Hamilton N. &ldquo;Gluconeogenesis in Leishmania mexicana: contribution of glycerol kinase, phosphoenolpyruvate carboxykinase, and pyruvate phosphate dikinase.&rdquo; J Biol Chem. 2014 Nov 21;289(47):32989-3000. Link 

Licensing Opportunity

50 mL of each are available for non-exclusive licensing.]]></description><pubDate>Mon, 12 Dec 2016 15:35:02 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/23687</guid></item><item><title>A Low-latency Routerless On-chip Network Design for Many-core Processors and Accelerators</title><caseId>OSU-16-09</caseId><link>http://icoregon.technologypublisher.com/technology/22861</link><description><![CDATA[Technology Description &nbsp; The proposed design does not have any on-chip routers, hence it is called routerless design. It also incorporates a layered network which is a mesh like structure that allows the packets to be sent to various core locations. The routerless NoC design also includes circles, traditionally known as rings which ensure an optimal hop count. A low average hop count is optimal because this ensures that the packets need not traverse long distances to reach their destination. This in turn is essential in saving power costs. The circles are also important features because t...]]></description><pubDate>Wed, 14 Sep 2016 16:25:02 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22861</guid></item><item><title>Fast, Economical, and Convenient Heavy Metal Contamination Detection</title><caseId>OSU-16-24</caseId><link>http://icoregon.technologypublisher.com/technology/22851</link><description><![CDATA[Technology Description &nbsp;This technology describes an accurate, inexpensive, simple, and portable membrane-based lateral flow fluidic device, made with both patented and patent pending technologies, to detect copper at concentrations as low as 0.5 ppm. No pre-treatment of the raw sample is needed. With simple modifications, this method can be adapted to detect other targets at similar or better sensitivity. &nbsp;Features &amp; Benefits &nbsp;Simple and rapid analysis requiring no training or specific instruments Eliminates interferences at minimal cost while remaining insensitive to tempe...]]></description><pubDate>Tue, 13 Sep 2016 16:04:14 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22851</guid></item><item><title>Method for identifying Family-Member Specific Targets of Mono-PARPs</title><caseId>2162</caseId><link>http://icoregon.technologypublisher.com/technology/22760</link><description>Summary
Technology developed at OHSU provides a novel method to identify proteins regulated by PARP mono-ADP-ribosylation (MARylation), a post-translational modification carried out by the majority of enzymes within this family. This tool has the ability to link such PARPs to specific targets and broader biological pathways, thereby increasing our understanding of their signaling cascades to improve outcomes of translational research in support of drug development. 
Technology Overview
PARPs are powerful pharmaceutical targets due to their diverse physiological functions, but linking the large...</description><pubDate>Mon, 29 Aug 2016 16:36:54 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/22760</guid></item><item><title>Currant, Flowering ‘Oregon Snowflake’</title><caseId>OSU-14-14</caseId><link>http://icoregon.technologypublisher.com/technology/22632</link><description><![CDATA[Technology Description

&lsquo;Oregon Snowflake&rsquo; resulted from a mutation breeding program that treated wild-collected seed with ethylmethane sulfonate (EMS) to induce variation with the goal of developing more compact forms of flowering currant. &lsquo;Oregon Snowflake&rsquo; was selected for its highly dissected, lacy foliage that is unique among available flowering currant cultivars. This plant has been serially propagated by stem cuttings over generations and roots readily from softwood cuttings collected late spring to summer. It has been observed to maintain its characteristics thr...]]></description><pubDate>Mon, 08 Aug 2016 13:42:42 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22632</guid></item><item><title>A cellular model for human pantothenate kinase 2 dysfunction</title><caseId>2184</caseId><link>http://icoregon.technologypublisher.com/technology/22398</link><description><![CDATA[
Technology Overview
Researchers at Oregon Health &amp; Science University have developed the first and only cell based PKAN model whereby human fibroblasts with respiratory dysfunction are maintained and utilized to screen compounds for biological activity against PKAN cellular phenotypes associated with PANK2 gene mutations. 

Licensing Opportunity

This technology is available for licensing.]]></description><pubDate>Tue, 05 Jul 2016 15:29:09 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/22398</guid></item><item><title>PVP Wheat, Soft White Winter 'ORCF-102' - Clearfield®</title><caseId>OSU-05-16</caseId><link>http://icoregon.technologypublisher.com/technology/22271</link><description>Technology Description    
ORCF-102 also has more acreage planted in than any other variety in Oregon and Washington. ORCF-102 is best adapted to dryland and irrigated wheat-growing regions in northeast Oregon and southeast Washington. ORCF-102 is a cross between Madsen, FS-4, and Wheatherford. It is an awned, medium-tall stature, medium maturity variety with superior straw strength proven performance, and is broadly adapted. ORCF-102 is resistant to strawbreaker footrot, and is also tolerant to Cephaloporium stripe and Fusarium crown rot. This variety also has excellent emergence and performa...</description><pubDate>Thu, 16 Jun 2016 16:22:34 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22271</guid></item><item><title>An Integrated WiFi and Free-space Optic Communication System (WiFIFO)</title><caseId>OSU-14-52</caseId><link>http://icoregon.technologypublisher.com/technology/22264</link><description><![CDATA[&nbsp;Technology Description &nbsp;In addition to normal WiFi transmission, a network of FSO transmitters can be placed in appropriate spots in a room to provide local high-rate FSO transmissions. The system monitors and manages the connections based on the FSO and WiFi channel conditions. The feedback information from the receiver to the AP is sent via WiFi channel. The movement patterns and locations of a user, relative to the transmitters, determine the amount of additional FSO bandwidth for the user. This alleviates the stress of how much bandwidth is going over the WiFi transmission, lead...]]></description><pubDate>Thu, 16 Jun 2016 13:44:57 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22264</guid></item><item><title>Universal modular bicycle gutter</title><caseId>1451</caseId><link>http://icoregon.technologypublisher.com/technology/22228</link><description><![CDATA[
Summary

The current technology is a system that allows cyclists to more easily carry bikes up and down stairs, allowing both commercial and residential buildings to improve usability for bicycle commuters. &nbsp;

Technology Overview

Bicycles and other wheeled conveyances have difficulty traversing stairs. People and riders frequently must pick up the bike and carry it up or down the stairs. The &ldquo;Modular Bicycle Gutter&rdquo; was designed to make stairway access easier for bicycles. It is a channel composed of interlocking beams and a rail based mounting system to be installed on exis...]]></description><pubDate>Mon, 13 Jun 2016 10:51:53 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/22228</guid></item><item><title>Segmented Flow for a Continuous Flow Microwave Reactor</title><caseId>OSU-13-27</caseId><link>http://icoregon.technologypublisher.com/technology/22071</link><description><![CDATA[&nbsp;Technology Description &nbsp;This invention is a continuous, segmented flow reactor system and method for the production of high quality NCs with microwave radiation. The system for NCs synthesis consists of an NC precursor configured to include an NC precursor solution with the ability to include a microwave reactor, segmentation fluid source, or other configurations depending on the nature of the application. The method for synthesizing NCs includes the step of providing and then segmenting the NC precursor solution with an immiscible segmentation fluid. The segmented NCs precursor sol...]]></description><pubDate>Tue, 24 May 2016 15:07:50 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22071</guid></item><item><title><![CDATA[The Hybrid Solid State-Scintillator for Alpha Gamma/x-ray & Neutron Detection]]></title><caseId>OSU-14-02</caseId><link>http://icoregon.technologypublisher.com/technology/22069</link><description><![CDATA[&nbsp;Technology Description &nbsp;This device replaces the PMT of a scintillation-based detector with thin-film materials. The photovoltaic and photo-thermoelectric properties of these materials, allow it to collect photoelectrons directly instead of relying on the PMT. Thin-films will generate photoelectrons upon absorbing photons emitted from the scintillation crystal that has absorbed radiation. The result is a light-harvesting device that is more robust, small, and inexpensive without using a photomultiplier. This device could also require an extremely small external bias needed to collec...]]></description><pubDate>Tue, 24 May 2016 14:55:37 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22069</guid></item><item><title>Engineering Mechanisms to Connect One Muscle to Multiple Tendons in Surgery</title><caseId>OSU-13-80</caseId><link>http://icoregon.technologypublisher.com/technology/22068</link><description><![CDATA[&nbsp;Technology Description &nbsp;This technology is a new tendon-transfer surgical procedure that uses an implanted passive engineering mechanism for attaching multiple tendons to a single donor muscle. This improves hand function in physical interaction tasks such as grasping over the conventional method of directly suturing multiple tendons to a single muscle.&nbsp;Features &amp; Benefits &nbsp;Improved individual finger adaption and reduced slip by 52%Reduced actuation force required to close all four fingers around an object by 45%&nbsp;Applications&nbsp;Tendon-transfer surgeries where o...]]></description><pubDate>Tue, 24 May 2016 14:10:01 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22068</guid></item><item><title>Direction-Sensitive Radiation Detector for Unmanned Vehicles</title><caseId>OSU-14-18</caseId><link>http://icoregon.technologypublisher.com/technology/22066</link><description>Low-cost, lightweight, and high-performance fully digital real-time pulse processing on board 

Background   
Finding and identifying radiation sources or illicit special nuclear materials (SNM) are vital to such efforts as emergency response and border security. It requires a radiation detection system capable of locating any radioisotopes present in the surrounding area in a very short-time operation. Current hand-held detectors do not have a directional capability, and the source must be found by carrying the detector over the suspect area a number of times and observing changes in count ra...</description><pubDate>Tue, 24 May 2016 13:42:03 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22066</guid></item><item><title>Fiber Optic Infrared Absorption Gas Sensors with Metal-Organic Framework Materials</title><caseId>OSU-14-60</caseId><link>http://icoregon.technologypublisher.com/technology/22054</link><description><![CDATA[&nbsp;Technology Description &nbsp;The fiber-optic chemical sensing platform couples light guides with a metal-organic framework (MOF) and plasmonic nanomaterial sensing components to provide increased near-infared (NIR) detection sensitivity. The MOF thin films rapidly absorb and sense gases by leveraging a network of plasmonic nanocrystals that act at the NIR range to concentrate light waves and precisely analyze the quantities of different trace-level gases and volatile organic compounds (VOC&rsquo;s). The MOF can be tuned to increase sensitivity and specific signal transduction for selecte...]]></description><pubDate>Mon, 23 May 2016 16:57:13 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22054</guid></item><item><title>Contour Connection Method: A DEM-Based Landslide Inventorying Algorithm</title><caseId>OSU-14-68</caseId><link>http://icoregon.technologypublisher.com/technology/22053</link><description><![CDATA[&nbsp;Technology Description &nbsp;Researchers at Oregon State University have developed a streamlined method that uses software to process some basic bare earth lidar data inputs, returning identity and class of possible landslide locations, enabling improved resource allocation in landslide risk assessment and mitigation. The technology uses a novel algorithm to automatically and consistently detect landslide deposits on a landscape scale. The algorithm implements a Contour Connection Method (CCM) based primarily on bare earth lidar data while requiring minimal user input. The output is inte...]]></description><pubDate>Mon, 23 May 2016 16:36:29 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22053</guid></item><item><title>Low-cost and Low-power Radiation Spectrometer</title><caseId>OSU-14-69</caseId><link>http://icoregon.technologypublisher.com/technology/22052</link><description>Works by detecting gamma-rays from the surrounding area and generating an energy spectrum based on the readings 

Background   
Gamma ray spectrometers are an essential part of labs, hospitals, power plants, and any other situation where there is a risk of exposure to gamma ray radiation. Gamma ray exposure increases the risk of cancer, and can cause genetic mutations and radiation sickness. However, modern gamma ray spectrometers are expensive, unwieldy, and require a large amount of power to use. Therefore, there is a significant role in radiation safety that can be played by a compact, low-...</description><pubDate>Mon, 23 May 2016 16:24:53 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22052</guid></item><item><title>Printable Conductive Inks</title><caseId>OSU-15-18</caseId><link>http://icoregon.technologypublisher.com/technology/22044</link><description><![CDATA[
Background of Invention

&nbsp;

Silver possesses excellent electrical conductivity, surface plasmon resonance, and high reflectivity, leading to its use in a wide variety of applications including microelectronic circuitry, gas sensors, low emissivity coatings and transparent conductive electrodes. Significant effort has been made toward the development of printable silver inks using nanoparticle suspensions and organo-metallic precursors. However, challenges remain in producing reliable, highly conductive, small scale features due to the stability of ink precursors, consistency of nanoparti...]]></description><pubDate>Mon, 23 May 2016 14:12:26 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22044</guid></item><item><title>Method for Protecting Location Privacy of Mobile Data Users</title><caseId>OSU-16-14</caseId><link>http://icoregon.technologypublisher.com/technology/22037</link><description><![CDATA[&nbsp;Technology Description &nbsp;This algorithm enables an efficient scheme for cooperative spectrum sensing that protects the location privacy of SU&rsquo;s with a low cryptographic overhead while guaranteeing an efficient spectrum sensing. This scheme is secure and robust against users dynamism, failures, and user maliciousness. Our performance analysis indicates that this scheme is significantly more efficient than all other counterpart schemes in terms of computation and communication overhead, even for increased values of the security parameters, but with the cost of including an additi...]]></description><pubDate>Fri, 20 May 2016 16:42:26 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22037</guid></item><item><title>Fiducial Marker for CT and MRI</title><caseId>OSU-15-33</caseId><link>http://icoregon.technologypublisher.com/technology/22017</link><description><![CDATA[&nbsp;Technology Description &nbsp; Attachable fiducial marker with optimized contrast medium that provides optimal imaging in CT and MRI. The marker is easily attached to body of a patient and features proven dual imaging capability that simplifies workflow to save time and money. The triangular design with single side crimp provides for fast and accurate linking of the location of a disease on CT or MRI images to the location of the disease within the patient. The markers are easy to manufacture and can be made from almost any plastic or elastomeric material, such as polyvinyl chloride, poly...]]></description><pubDate>Fri, 20 May 2016 10:25:03 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/22017</guid></item><item><title>Antiproliferative Peptide Coibamide A</title><caseId>OSU-06-52</caseId><link>http://icoregon.technologypublisher.com/technology/21995</link><description>Background   
Cancer is one of the leading causes of morbidity and mortality worldwide, and the number of cases is expected to rise to 22 million over the next 2 decades. Modified natural products continue to be an important source for new drugs that address unmet needs in the battle against cancer.  

Technology Description    
Researchers at Oregon State University have discovered, isolated, and purified a new antiproliferative compound, Coibamide A, which provides for a new and potent family of antiproliferative compounds. The peptidic molecular structure of Coibamide A presents a large num...</description><pubDate>Thu, 19 May 2016 09:55:41 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21995</guid></item><item><title>Novel Color Pigments Based On AM12O19 Oxides</title><caseId>OSU-13-74</caseId><link>http://icoregon.technologypublisher.com/technology/21956</link><description><![CDATA[&nbsp;Technology Description &nbsp;Colors available for these new pigments are different shades of blue, pink, rosy, golden brown, turquoise and more. Specifically, this technology describes a nontoxic, inexpensive and stable blue pigment superior to commercially available ones based on CoAl2O4.&nbsp;Features &amp; Benefits &nbsp;New blue colors are durable, nontoxic, and inexpensiveDemonstrate better Near Infrared Reflectance (NIR) than Co blue pigment CoAl2O4Can be easily prepared through traditional ceramic powder processing techniques in air&nbsp;&nbsp;Background of Invention &nbsp;Many ex...]]></description><pubDate>Tue, 17 May 2016 11:47:49 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21956</guid></item><item><title>Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity</title><caseId>OSU-06-56</caseId><link>http://icoregon.technologypublisher.com/technology/21952</link><description>Background   
The global emergence of multi-drug resistant bacterial infections has resulted in enormous costs and has become a major threat to public health. About seventy percent of nosocomial infections are resistant to at least one commonly use antibiotic. Pactamycin is a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum. Its promising antitumor, antiviral, and anti-protozoal activities make pactamycin a promising parent compound for drug development that shows potent antimicrobial activity. Unfortunately, its development as a clinical compound has been hampere...</description><pubDate>Tue, 17 May 2016 10:22:26 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21952</guid></item><item><title>Low Cost Methods for Producing Microchannel Process Technology</title><caseId>OSU-12-53</caseId><link>http://icoregon.technologypublisher.com/technology/21951</link><description>A manufacturing architecture that uses microchannel flow inserts to enable stamping and avoid photochemical etching 

Background   
Microchannel process technology is useful in a variety of applications including heat exchangers, solar cells, hydrogen storage, and chemical reactors. The surface-area-to-volume ratios of microchannels are as large as possible to promote fast and efficient heat transfer. Microchannels are typically fabricated from expensive metal alloys to accommodate high temperature/high pressure fluid flow and/or corrosive fluids. Microchannel arrays are typically fabricated u...</description><pubDate>Tue, 17 May 2016 10:07:06 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21951</guid></item><item><title>Natural dairy product biopolymer thickener from Lactococcus lactis Ropy352</title><caseId>OSU-99-07</caseId><link>http://icoregon.technologypublisher.com/technology/21926</link><description><![CDATA[&nbsp;Technology Description &nbsp;Natural polysaccharides produced by Ropy352 gives the yogurt a thick, smooth and sweet taste and are generally considered safe. Therefore, no other polysaccharides, like dextran, xanthan, and gellan from potentially pyrogenic inducing bacteria, are needed.&nbsp;Features &amp; Benefits &nbsp;Natural and Generally Regarded As Safe (GRAS)Yogurt made from low-fat or non-fat milk with Ropy352 having appealing texture and tasteNo additional thickener needed, a strong market appeal for nature and health conscience consumersStrong patent position&nbsp;Applications&nb...]]></description><pubDate>Fri, 13 May 2016 15:15:40 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21926</guid></item><item><title>New Approach for Treatment of Type I Diabetes</title><caseId>OSU-14-54</caseId><link>http://icoregon.technologypublisher.com/technology/21924</link><description>Technology Description

This licensing and collaborative research opportunity relates to a new approach to treating diabetes mellitus type 1 (T1DM). The patent pending methods of treatment focus on the use of compounds that provide suppression of autoimmune responses that lead to destruction of pancreatic beta cells. The possibility of preventing disease progression offers a new paradigm in managing T1DM, which may provide patients with the opportunity to avoid dependence on insulin therapy and the numerous disease complications. Based on small-molecule screening for ligands of the Ah receptor...</description><pubDate>Fri, 13 May 2016 14:54:13 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21924</guid></item><item><title>Kisspeptin Neuronal Cell Lines</title><caseId>OSU-15-41</caseId><link>http://icoregon.technologypublisher.com/technology/21920</link><description><![CDATA[&nbsp;Background of Invention &nbsp;Kisspeptin is an important neuropeptide produced by distinct neuronal clusters in the Arcuate nucleus and anteroventral periventricular nuclei of the hypothalamus. It plays a key role in sexual differentiation of the brain, puberty onset, and metabolic control of fertility. It is required for reproduction. There is great interest in understanding the molecular mechanisms of kisspeptin transcriptional regulation, release, and control by sex steroid hormones. However, available cell lines do not represent the distinct populations of the Arcuate nucleus and AVP...]]></description><pubDate>Fri, 13 May 2016 14:13:00 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21920</guid></item><item><title>PVP Wheat, Soft White Winter 'ORCF-103' - Clearfield®</title><caseId>OSU-08-46</caseId><link>http://icoregon.technologypublisher.com/technology/21919</link><description><![CDATA[Technology Description    
ORCF-103 is best adapted to dryland wheat-growing regions in north-central Washington (blue shaded areas). Secondary areas of adaption (red regions) are the larger dryland wheat-growing regions in northeast Oregon and southwest Washington.

ORCF-103 is a cross between Eltan, FS-4, Stephens, and Madsen. It is an awned, intermediate stature, medium-late maturity variety with moderate straw strength. Not only is this variety high yielding, but what really sets ORCF-103 apart from OSU&rsquo;s other CLEARFIELD varieties is its exceptional winter hardiness with good emerge...]]></description><pubDate>Fri, 13 May 2016 14:10:59 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21919</guid></item><item><title>Hazelnut 'McDonald'</title><caseId>OSU-14-07</caseId><link>http://icoregon.technologypublisher.com/technology/21913</link><description><![CDATA[&nbsp;Technology Description &nbsp;&lsquo;McDonald&rsquo; inherits a gene from the cultivar &lsquo;Gasaway&rsquo;, which confers a high level of resistance to EFB; trees remain mostly free of EFB, with only a few cases of small cankers under high disease pressure having been observed to date. Additionally, &lsquo;McDonald&rsquo; is resistant to bud mites (primarily Phytoptus avellanae Nal.) and has very few moldy kernels. Its nuts mature two weeks earlier than 'Barcelona', increasing the chance that they can be harvested before fall rains begin, reducing cleaning and drying costs to growers. N...]]></description><pubDate>Fri, 13 May 2016 11:39:01 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21913</guid></item><item><title>Hazelnut 'Wepster'</title><caseId>OSU-13-07</caseId><link>http://icoregon.technologypublisher.com/technology/21912</link><description><![CDATA[
&nbsp;

Technology Description

&nbsp;

&lsquo;Wepster&rsquo; inherits a gene from the cultivar &lsquo;Gasaway&rsquo;, which confers a high level of resistance to EFB; trees remain mostly free of EFB, with only a few cases of small cankers under high disease pressure having been observed. Additionally, &lsquo;Wepster&rsquo; is resistant to bud mite (primarily Phytoptus avellanae Nalepa) and has very few moldy kernels. The nuts of &lsquo;Wepster&rsquo; mature at least one week earlier than &#39;Barcelona&rsquo;, are small in size and have 46% kernel, by weight. &lsquo;Wepster&rsquo; trees can ...]]></description><pubDate>Fri, 13 May 2016 11:30:14 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21912</guid></item><item><title>Hazelnut, Ornamental Corylus avellana 'Red Dragon'</title><caseId>OSU-08-09</caseId><link>http://icoregon.technologypublisher.com/technology/21910</link><description>Technology Description   
Red Dragon has received high ratings as an ornamental type for contorted growth habit, twig density and maroon-red leaf color retention. Other desirable features of Red Dragon include, moderate to high vigor (for easy propagation), optimal branch spreading and a dense canopy. The nuts are slightly long and produced in clusters of one or two. Benefits include: Resistant to eastern filbert blight; Requires minimal pruning; Red leaves, flowers, husks and nuts create a uniform red canopy; Blight resistance combined with ornamental properties make Red Dragon suitable for l...</description><pubDate>Thu, 12 May 2016 16:46:38 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21910</guid></item><item><title>PVP Wheat, Common 'ORCF-101' - Clearfield®</title><caseId>OSU-03-22</caseId><link>http://icoregon.technologypublisher.com/technology/21909</link><description><![CDATA[Technology Description    
ORCF-101, Soft White Winter Wheat w/ Herbicide Resistance Trait ORCF-101 is best adapted to dryland regions of Wasco, Sherman, Gilliam, and Morrow counties in Oregon (blue areas). Secondary areas of adaption (red regions) are the dryland areas of eastern Oregon and southeastern Washington.

ORCF-101 is a cross between FS-4, Malcolm, Stephens, and Madsen. It is an awned, medium statured, semi-dwarf variety with midseason maturity and high yield potential. The maturity, adaption, and test weight is that compared to &lsquo;Stephens&rsquo;. ORCF-101 also has excellent em...]]></description><pubDate>Thu, 12 May 2016 16:05:20 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21909</guid></item><item><title>PVP Wheat, Hard Red Winter 'Norwest 553'</title><caseId>OSU-07-48</caseId><link>http://icoregon.technologypublisher.com/technology/21908</link><description><![CDATA[Technology Description    
&lsquo;Norwest 553&rsquo; is best adapted to the high rainfall and irrigated regions of eastern Oregon and Washington (blue areas). A secondary area of adaption is the low-to-medium rainfall regions of eastern Oregon and Washington (red areas). &lsquo;Norwest 553&rsquo; is awned, short stature, mid-season maturity, with superior straw strength. In addition, &lsquo;Norwest 553&rsquo; has superior yield potential, especially in high yield environments. It is resistant to stripe rust and moderately resistant to Cephalosporium stripe, Fusarium crown rot, Septoria leaf bl...]]></description><pubDate>Thu, 12 May 2016 16:03:12 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21908</guid></item><item><title>PVP Potato 'Owyhee Russet' (Oregon Tri-State)</title><caseId>OSU-09-13</caseId><link>http://icoregon.technologypublisher.com/technology/21907</link><description>Technology Description   
Owyhee Russet, known as AO96160-3 prior to release, is a mid to late season russet variety with good appearance and processing quality. It produces reasonable yields with a high percentage of U.S. No. 1 tubers with relatively good size uniformity. It has high specific gravity, light fry color, few sugar ends, and few internal and external tuber defects. It is resistant to common scab and Fusarium dry rot and has moderate susceptibility to PVY and PLRV.

Background of Invention
Owyhee Russet has been exclusively licensed for production and sale through the Potato Varie...</description><pubDate>Thu, 12 May 2016 13:51:02 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21907</guid></item><item><title>PVP Potato 'Purple Pelisse' (Oregon Tri-State)</title><caseId>OSU-09-12</caseId><link>http://icoregon.technologypublisher.com/technology/21904</link><description>Technology Description   
Purple Pelisse (POR01PG16-1) is a mid season specialty potato with purple skin and dark purple flesh. This selection is unique among commercially available purple varieties in that plants set a large number of smooth, small, fingerling-shaped tubers. Tubers are ideal for boiling or baking whole. Chips made from Purple Pelisse tubers retain their bright purple color and resist fading.

Purple Pelisse produces small fingerling-shaped tubers with purple skin and dark purple flesh. Tubers are smooth with shallow eyes that are concentrated at the bud end of the tuber with ...</description><pubDate>Thu, 12 May 2016 11:46:58 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21904</guid></item><item><title>Hazelnut 'Felix' [OSU 941.016]</title><caseId>OSU-12-16</caseId><link>http://icoregon.technologypublisher.com/technology/21903</link><description><![CDATA[Technology Description    
&lsquo;Felix&rsquo; carries the &lsquo;Gasaway&rsquo; gene, giving it resistance to EFB. Additionally, &lsquo;Felix&rsquo; is resistant to big bud mite (primarily Phytoptus avellanae Nal.), has very few nut defects, and its well-filled nuts are 50% kernel by weight. &lsquo;Felix&rsquo; has the incompatibility alleles S5 and S21, with S5 being expressed in the pollen. The S5 allele is not common and its pollen will be compatible on most other hazelnut cultivars. &lsquo;Felix&rsquo; sheds pollen later than most other cultivars, making it a useful pollinizer for hazelnu...]]></description><pubDate>Thu, 12 May 2016 11:26:01 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21903</guid></item><item><title>C57BL6-Pahenu2 mouse</title><caseId>1978</caseId><link>http://icoregon.technologypublisher.com/technology/21793</link><description><![CDATA[
Technology Overview

The C57BL6-Pahenu2 mouse is a model of the human disease phenylketonuria (PKU).&nbsp; The mouse was originally on the BTBR genetic background but the mutation was outbred to the C57BL6 background to facilitate breeding.&nbsp; 

Licensing Opportunity

This mouse is available for academic research and non-exclusive licensing. ]]></description><pubDate>Wed, 20 Apr 2016 14:12:40 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21793</guid></item><item><title>Hazelnut 'Burgundy Lace'</title><caseId>OSU-15-24</caseId><link>http://icoregon.technologypublisher.com/technology/21725</link><description><![CDATA[&nbsp;Technology Description &nbsp;Leaves of &lsquo;Burgundy Lace&rsquo; are dark reddish purple when young, are deeply incised and narrower than most European hazelnut cultivars, which have green leaves that are round-ovate and un-dissected. This results in a tree canopy that appears lacey and delicate. &lsquo;Burgundy Lace&rsquo; inherited resistance from the cultivar &lsquo;Gasaway&rsquo; to the Oregon race of Anisogramma anomala, the fungus that causes eastern filbert blight, the principle disease of hazelnuts in the United States. The growth habit and moderate vigor of &lsquo;Burgundy Lac...]]></description><pubDate>Mon, 11 Apr 2016 10:22:17 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21725</guid></item><item><title>Microchannel-based Capacitive Desalination Technology</title><caseId>OSU-13-23</caseId><link>http://icoregon.technologypublisher.com/technology/21650</link><description>A novel microchannel architecture with laminated construction for capacitive desalination 

Background   
The need for potable water is one of the most important challenges in the world. Seawater is readily abundant yet existing methods of purification are expensive and energy intensive. The three primary technologies currently used for seawater desalination (flash distillation, multi-effect desalination, and reverse osmosis filtration) all require large amounts of energy. The first two rely on thermal processes and require large amounts of heat, and the latter processes drive water through RO...</description><pubDate>Thu, 31 Mar 2016 14:08:47 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21650</guid></item><item><title>T2* Mapping for quantitative assessment of placental function and oxygenation</title><caseId>1991</caseId><link>http://icoregon.technologypublisher.com/technology/21561</link><description>
Summary

The current method provides a noninvasive means of assessing placental function and oxygenation from MRI images without the administration of an exogenous contrast agent, to provide a safer means to asses placental health during pregnancy.

Technology Overview

Despite recent focus on placental health and function as a primary driver of fetal growth and development, current in vivo identification and assessment of abnormal placentation is limited. This MRI protocol and modeling methodology, which uses an endogenous contrast agent and therefore is non-invasive, facilitates assessment ...</description><pubDate>Mon, 14 Mar 2016 13:35:03 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21561</guid></item><item><title>Compounds that bind macrophage migration inhibitory factor</title><caseId>2165</caseId><link>http://icoregon.technologypublisher.com/technology/21486</link><description><![CDATA[
Summary
Recombinant polypeptide composition, which selectively block key pro-inflammatory factors that could stop multiple sclerosis (MS) progression.&nbsp;

Technology Overview
MIF acts on the immune system to recruit inflammatory factors within injured tissues, including the central nervous system in MS. Upon binding to its receptor, CD74, MIF activates pathways to promote inflammation. The current composition competes with MIF to bind to CD74 thereby inhibiting inflammation. Derived from CD74, the new composition competes for binding of the CD74 ligand, macrophage migration inhibitory fact...]]></description><pubDate>Tue, 01 Mar 2016 15:13:50 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21486</guid></item><item><title>Mouse CD74: Design, codon optimization, cloning, expression in E coli, and purification</title><caseId>2187</caseId><link>http://icoregon.technologypublisher.com/technology/21485</link><description><![CDATA[
Summary

Recombinant mouse CD74 for use as a research reagent to explore CD74 protein interactions.

Technology Overview&nbsp;

This recombinant mouse CD74 is a 191 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed mouse protein that includes the intracellular domain (N-terminal amino acid residues 1 to 30), the transmembrane domain (amino acid residues 31 to 55) and the extracellular domain (amino acid residues 56 to 191). This protein would be useful for studies aimed at exploring protein-protein interactions, for blocking experiments ...]]></description><pubDate>Tue, 01 Mar 2016 15:05:16 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21485</guid></item><item><title>Genetic incorporation of tetrazine amino acids and use in bioorthogonal ligations</title><caseId>OSU-14-16</caseId><link>http://icoregon.technologypublisher.com/technology/21416</link><description><![CDATA[
Technology Description

&nbsp;

Ideal bioorthogonal reactions containing high reaction rates, high selectivity and high stability would allow for stoichiometric labeling of biomolecules in minutes and eliminate the need to washout excess labeling reagent. Currently no general method exists for controlled stoichiometric or sub-stoichiometric labeling of proteins in live cells. To overcome this limitation we have developed a faster more stable tetrazine-containing amino acid (Tet-2.0) and have genetically encoded this amino acid in response to an amber codon. We have demonstrated that in vivo r...]]></description><pubDate>Thu, 11 Feb 2016 14:35:17 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/21416</guid></item><item><title>Anti-CB1 / Anti-CNR1 monoclonal antibodies: (clone 3A3 - conformationally sensitive)</title><caseId>1744-A</caseId><link>http://icoregon.technologypublisher.com/technology/21207</link><description><![CDATA[
Technology Overview

The mouse monoclonal antisera against human Cannabinoid Receptor 1 (anti-CB1, anti-CNR1). Clone: 3A3. The laboratory of Dr. David Farren&rsquo;s has produced the only monoclonal antibodies on the market that recognizes the well conserved 3rd intracellular loop of CB1 (connecting transmembrane domains 5 and 6). Antiserum from clone 3A3&nbsp;can recognize native, solubilized CB1 receptor in fluorescence detected size-exclusion chromatography.

Antibody:&nbsp;anti-CB1

Hybridoma cell line:&nbsp;Clone 3A3
Isotype:&nbsp;Mouse IgG2b, kappa
Species reactivity:&nbsp;Human (may cr...]]></description><pubDate>Wed, 30 Dec 2015 13:56:24 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21207</guid></item><item><title>Anti-CB1 / Anti-CNR1 Monoclonal Antibodies: (Clone 5G3)</title><caseId>1744-B</caseId><link>http://icoregon.technologypublisher.com/technology/21206</link><description><![CDATA[Technology Overview

The mouse monoclonal antisera against human Cannabinoid Receptor 1 (anti-CB1, anti-CNR1). Clone: 5G3. The laboratory of Dr. David Farren&rsquo;s has produced the only monoclonal antibodies on the market that recognizes the well conserved 3rd intracellular loop of CB1 (connecting transmembrane domains 5 and 6). Antiserum from clone 5G3 can recognize native, solubilized CB1 receptor in fluorescence detected size-exclusion chromatography.

Antibody:&nbsp;anti-CB1
Hybridoma cell line:&nbsp;Clone 5G3
Isotype:&nbsp;Mouse IgG2a, kappa
Species reactivity:&nbsp;Human (may cross rea...]]></description><pubDate>Wed, 30 Dec 2015 13:56:14 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21206</guid></item><item><title>Anti-CB1 / Anti-CNR1 Monoclonal Antibodies: (Clone 6E2)</title><caseId>1744-C</caseId><link>http://icoregon.technologypublisher.com/technology/21205</link><description><![CDATA[Technology Overview

The mouse monoclonal antisera against human Cannabinoid Receptor 1 (anti-CB1, anti-CNR1). Clone: 6E2. The laboratory of Dr. David Farren&rsquo;s has produced the only monoclonal antibodies on the market that recognizes the well conserved 3rd intracellular loop of CB1 (connecting transmembrane domains 5 and 6). 

Antibody:&nbsp;anti-CB1
Hybridoma cell line:&nbsp;Clone 6E2
Species reactivity:&nbsp;Human (may cross react with mouse and rat)
Concentration:&nbsp;1.0 mg/mL
Applications:&nbsp;Western blot (1:50,000)
Availability:&nbsp; The price below is for 100 ug of antisera.&n...]]></description><pubDate>Wed, 30 Dec 2015 13:56:01 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/21205</guid></item><item><title>Lymphatic drug delivery system and drugs for metastatic melanoma</title><caseId>OSU-15-31</caseId><link>http://icoregon.technologypublisher.com/technology/20948</link><description><![CDATA[Technology Description &nbsp;Oregon State University is seeking a licensee for a patented drug delivery system for the treatment of metastatic melanoma. The system is composed of biodegradable, biocompatible, and stable nanoparticles built from amphiphilic block copolymers and contains a mix of drugs commonly used to treat cancer, all while being nontoxic to healthy cells. In one example, a synergistic three-drug combination loaded into nanoparticles was used for in vivo studies of two metastatic mouse models covering mutations in NRAS or RXR&alpha; showed highly effective treatment for melano...]]></description><pubDate>Mon, 23 Nov 2015 14:49:34 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/20948</guid></item><item><title>PVP Potato 'Klamath Russet' (Oregon Tri-State)</title><caseId>OSU-00-15</caseId><link>http://icoregon.technologypublisher.com/technology/20580</link><description><![CDATA[Features &amp; Benefits    


	Consistently produces higher total yields and much higher yields of U.S. No. 1s with larger tuber size than Russet Burbank or Russet Norkotah
	Higher in sugars than and similar in vitamin C and protein to Russet Burbank
	Very resistant to common scab, moderately resistant to verticillium wilt, very susceptible to potato leafroll virus


Status    
Klamath Russet is available for license through the Potato Management Variety Institue, Inc. (PVMI). Please go to www.pvmi.org for more information about license details.]]></description><pubDate>Thu, 22 Oct 2015 08:41:09 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/20580</guid></item><item><title>Sensor for Akt kinase activity in living cells</title><caseId>2049</caseId><link>http://icoregon.technologypublisher.com/technology/20479</link><description><![CDATA[
Technology Overview

Researchers at Oregon Health &amp; Science University have developed a novel Akt biosensor which provides a robust readout for the PI3-kinase signaling pathway in living cells without the use complex microscopy techniques. This biosensor allows quantitative tracking of Akt activity for days in individual cells within a population, and responds within minutes to changes in the signaling pathway that is altered in a variety of disease states and physiological conditions. The biosensor provides a greater dynamic range, is more sensitive and more specific to changes in Akt ac...]]></description><pubDate>Thu, 08 Oct 2015 16:32:38 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/20479</guid></item><item><title>Aptamer-siRNA chimera targeting RORγt in Th17 cells for topical therapy of psoriasis</title><caseId>1896</caseId><link>http://icoregon.technologypublisher.com/technology/20468</link><description><![CDATA[
Summary
Researchers at Oregon Health &amp; Science University and at the Portland VA Medical Center have discovered and validated a novel aptamer-siRNA chimera targeting ROR&gamma;t in Th17 cells for topical treatment of psoriasis.

Technology Overview
Th17 cells produce several inflammatory cytokines, including IL-17, IL-17F, IL-22 and IL-21 which all have been implicated in mediating the chronic inflammation that is characteristic of a number of autoimmune inflammatory diseases. These include rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, psoriasis, inflammatory bow...]]></description><pubDate>Wed, 07 Oct 2015 14:33:08 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/20468</guid></item><item><title>ACE-15, a brief psychometric measure of clinical teamwork skills</title><caseId>2158</caseId><link>http://icoregon.technologypublisher.com/technology/20303</link><description>
Technology Overview

The ACE-15: Assessment for Collaborative Environments is a brief assessment form to evaluate a full range of clinical settings. It is a 1 page 15 item Likert-type measurement tool that can be used to quickly assess clinical teamwork skills in a variety of clinical settings.

Licensing Opportunity

This form is available for licensing.</description><pubDate>Fri, 18 Sep 2015 13:12:17 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/20303</guid></item><item><title>Novel biosensor for direct measurement of bioavailable NAD+</title><caseId>1988</caseId><link>http://icoregon.technologypublisher.com/technology/20189</link><description><![CDATA[
Summary

This technology provides a unique cell-based platform for targeting NAD+-(nicotinamide adenine dinucleotide) regulatory pathways in the treatment of human diseases. An emerging theme in age-related pathologies&mdash;e.g. neurodegeneration, cancer, cardiovascular disease, inflammation, type 2 diabetes, and metabolic disease&mdash;is due to the misregulation of NAD+ metabolism and homeostasis. 

Technology Overview

NAD+ serves dual roles as both an intermediary metabolite and as a required co-substrate for Sirtuin and PARP enzymes, and thus is positioned centrally in a number of biolo...]]></description><pubDate>Fri, 28 Aug 2015 17:03:36 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/20189</guid></item><item><title>Guilty Except for Insanity - Maddening Journeys through an American Asylum - Documentary Film</title><caseId>MHAAJ-01</caseId><link>http://icoregon.technologypublisher.com/technology/19753</link><description><![CDATA[&nbsp;&nbsp;Guilty Except for Insanity: Maddening Journeys through an American AsylumAn educational documentary film directed by Dr. Jan Haaken&nbsp;The FilmIn Guilty Except for Insanity, Director and Professor of Psychology Jan Haaken goes behind the walls of the Oregon State Hospital, the location of One Flew Over the Cuckoo's Nest, and recounts the stories of real patients who enter this famous hospital for the &quot;criminally insane.&quot; Their stories reveal the craziness of an American System where one must commit a crime to receive psychiatric help. The documentary probes this maddeni...]]></description><pubDate>Thu, 11 Jun 2015 13:51:19 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/19753</guid></item><item><title>Graphene Supported Palladium Gold Hybrids as Efficient Catalyst for Waste-Water Purification</title><caseId>MJIAJ-05</caseId><link>http://icoregon.technologypublisher.com/technology/19747</link><description><![CDATA[&nbsp;&nbsp;Graphene Supported Palladium Gold Hybrids as Efficient Catalyst for Waste-Water PurificationFrom the Lab of Dr. Jun Jiao, Portland State University, Portland, OR, USA&nbsp;Portland State University is seeking partnerships for research and commercialization for select technologies developed in university laboratories. This document presents a nanocrystal technology that reclaims industrial waste water by processing toxins to purity levels acceptable for introduction to municipal water treatment systems.&nbsp;OpportunityDevelop disruptive technologies to change the way industrial, co...]]></description><pubDate>Thu, 11 Jun 2015 12:27:43 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/19747</guid></item><item><title>Transgenerational Enhancement of Plant Defenses</title><caseId>MBALD-01</caseId><link>http://icoregon.technologypublisher.com/technology/19742</link><description><![CDATA[&nbsp;Production of Resistant Plants Via Trans-generational Enhancement of Plant DefensesFrom the Lab of Dr. Daniel Ballhorn, Portland State University, Portland, OR, USA&nbsp;Portland State University is seeking partnerships for research and commercialization for select technologies developed in University laboratories. This document presents a method for the production of herbivore-resistant plants via trans-generational enhancement of plant defenses in agriculturally important crops* including lima beans, flax and white clover developed by Dr. Daniel Ballhorn.&nbsp;OpportunityA new technolo...]]></description><pubDate>Thu, 11 Jun 2015 11:01:58 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/19742</guid></item><item><title>Flexible, Reusable Electrodes for new Applications in Measuring Coating Integrity</title><caseId>MCLAT-02</caseId><link>http://icoregon.technologypublisher.com/technology/19741</link><description><![CDATA[&nbsp;Flexible, Reusable Electrodes for new Applications in Measuring Coating IntegrityFrom the Lab of Dr. Tami Lasseter Clare, Portland State University, Portland, OR, USA&nbsp;This technology is a patent pending* flexible hydrogel device for detecting the degradation of various thin coatings in variety of metrology and thin film applications.*Serial No. PCT/US2014/041743OpportunityInnovative new product line in impedance spectroscopy and measurement of coating integrity on metallic and nonmetallic surfaces.&nbsp;Application/AdvantagesElectrochemical Impedance Spectroscopy is a proven method ...]]></description><pubDate>Thu, 11 Jun 2015 10:08:15 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/19741</guid></item><item><title>Corrosion-free, Ultra-lightweight Buckling Restrained Braces</title><caseId>M.DUSP-01</caseId><link>http://icoregon.technologypublisher.com/technology/19696</link><description><![CDATA[&nbsp;Corrosion-free, Ultra-lightweight Buckling Restrained BracedFrom the Lab of Dr. Peter Dusicka, Portland State University, Portland, OR, USAPortland State University is seeking partnerships for research and commercialization for select technologies developed in university laboratories. This corrosion-free, ultra-lightweight buckling restrained brace design is intended for use in the construction of new buildings and is a cost-effective alternative for the seismic retrofitting of older buildings. The technology has been tested at full-scale.OpportunityInnovative new product line for seismi...]]></description><pubDate>Tue, 02 Jun 2015 09:03:36 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/19696</guid></item><item><title>Ultra-Lightweight Corrosion Free Buckling Restrained Brace</title><caseId>DUSP-01</caseId><link>http://icoregon.technologypublisher.com/technology/19695</link><description></description><pubDate>Tue, 02 Jun 2015 08:55:12 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/19695</guid></item><item><title>PVP Wheat [Weatherford]</title><caseId>OSU-98-0</caseId><link>http://icoregon.technologypublisher.com/technology/19498</link><description><![CDATA[OSU-98-06Weatherford is a soft white winter wheat released by Oregon State University. This variety is resistant to stripe rust and foot rot, susceptible to take-all, and moderately resistant to cephalosporium stripe. In addition, it has good milling quality and average baking characteristics. Wheatherford wheat is available as an open release.&nbsp;]]></description><pubDate>Wed, 20 May 2015 11:53:55 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/19498</guid></item><item><title>Durable dental composites</title><caseId>1962</caseId><link>http://icoregon.technologypublisher.com/technology/18823</link><description>Summary
A light-cured, dental resin composite for all types of restorations combining thiourethane oligomers with methacrylamide monomers to increase strength, biocompatibility, and durability.

Technology Overview
Current dental resin composites last, on average, between 5-10 years due to fracture and degradation. Polymerization shrinkage and stress cause degradation at the tooth interface leading to restoration failure. To date, materials developed to reduce polymerization shrinkage and stress have proven inefficient at extending the life span of restorations.

Researchers at the OHSU School...</description><pubDate>Fri, 03 Apr 2015 08:59:05 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18823</guid></item><item><title>Small molecule inhibitors of the mitochondrial permeability transition pore (PTP)</title><caseId>1967</caseId><link>http://icoregon.technologypublisher.com/technology/18173</link><description><![CDATA[
Summary
Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health &amp; Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. 

Technology Overview

The mitochondrial permeability transition pore (mtPTP) plays a key role in a wide variety of human diseases whose common pathology may be based in mitochondrial dysfunction; however, there are few small molecule inhibitors of mtPTP...]]></description><pubDate>Mon, 02 Feb 2015 13:19:50 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18173</guid></item><item><title>A guide for rapid assessment of antibodies following disclosure</title><caseId>2054</caseId><link>http://icoregon.technologypublisher.com/technology/18073</link><description><![CDATA[
Summary

A guide and decision for technology transfer professionals to assist in determining the appropriate commercialization strategies for academically developed antibodies.

Technology Overview

Antibodies are often developed as important tools during the course of fundamental and clinical research conducted at various universities and research institutions. These valuable reagents aid in research, diagnostics, and may be used as therapeutic agents.&nbsp;The global research antibody market is valued at $1.5B as of 2011 and is projected to grow at a rate of 2.9% over the following 5 years....]]></description><pubDate>Thu, 29 Jan 2015 10:20:54 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18073</guid></item><item><title>Oligonucleotides for long QT syndrome</title><caseId>2044</caseId><link>http://icoregon.technologypublisher.com/technology/18072</link><description>
Summary

The current technology consists for compositions under development for the treatment of cardiovascular arrhythmias, specifically Long-QT Syndrome.

Technology Overview

KCNH2, also known as ether-a-go-go related gene 1 (hERG1) encodes the Kv11.1 channel that conducts the rapidly activating delayed rectifier K+ current in the heart. These channels are essential for cardiac action potential repolarization. Mutations in KCNH2 cause long QT syndrome type 2 (LQT2), a disease associated with prolonged cardiac action potential duration and prolonged QT intervals on ECG, which can lead to ve...</description><pubDate>Thu, 29 Jan 2015 10:20:53 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18072</guid></item><item><title>Split-luciferase complementation to measure soluble epoxide hydrolase dimerization</title><caseId>1803</caseId><link>http://icoregon.technologypublisher.com/technology/18068</link><description><![CDATA[Technology Overview
Soluble epoxide hydrolase (sEH) inhibition is a therapeutic target for a large number of cardiovascular diseases. Disrupting dimerization of sEH reduces hydrolase activity and shifts the sub-cellular localization of sEH to peroxisomes. The current technology is a split-firefly luciferase assay that not only measures disruption of sEH dimerization as a means of inhibition, but also acts as a high throughput screen for small molecules that could inhibit sEH dimerization. 

Publication
Nelson JW, et. Al, &ldquo;Soluble epoxide hydrolase dimerization is required for hydrolase a...]]></description><pubDate>Thu, 29 Jan 2015 10:20:39 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18068</guid></item><item><title>Rabbit polyclonal antibody directed against human cytomegalovirus protein UL131</title><caseId>1260-E</caseId><link>http://icoregon.technologypublisher.com/technology/18055</link><description><![CDATA[Technology Overview
Rabbit polyclonal&nbsp;antisera against human cytomegalovirus (CMV) protein UL131 has been developed. This antisera&nbsp;is useful for research involving CMV. Please refer to the following publication for more information on this antisera. 

Aliquot provided: 0.5mL aliquots are provided. A minimum of three (3) aliquots of any combination of polyclonal antisera classified under OHSU Technology #1260 is required for each license/MTA.

Publication
Ryckman B.J., et al. Characterization of the Human Cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and ...]]></description><pubDate>Thu, 29 Jan 2015 10:20:25 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18055</guid></item><item><title>Rabbit polyclonal antibody directed against human cytomegalovirus protein UL130</title><caseId>1260-D</caseId><link>http://icoregon.technologypublisher.com/technology/18054</link><description><![CDATA[Technology Overview
Rabbit polyclonal&nbsp;antisera against human cytomegalovirus (CMV) protein UL130 has been developed. This antisera&nbsp;is useful for research involving CMV. Please refer to the following publication for more information on this antisera. 

Aliquot provided: 0.5mL aliquots are provided. A minimum of three (3) aliquots of any combination of polyclonal antisera classified under OHSU Technology #1260 is required for each license/MTA.

Publication
Ryckman B.J., et al. Characterization of the Human Cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and ...]]></description><pubDate>Thu, 29 Jan 2015 10:20:25 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18054</guid></item><item><title>Rabbit polyclonal antibody directed against human cytomegalovirus protein UL128</title><caseId>1260-C</caseId><link>http://icoregon.technologypublisher.com/technology/18053</link><description><![CDATA[Technology Overview
Rabbit polyclonal&nbsp;antisera against human cytomegalovirus (CMV) protein UL128 has been developed. This antisera&nbsp;is useful for research involving CMV. Please refer to the following publication for more information on this antisera. 

Aliquot provided: 0.5mL aliquots are provided. A minimum of three (3) aliquots of any combination of polyclonal antisera classified under OHSU Technology #1260 is required for each license/MTA.

Publication
Ryckman B.J., et al. Characterization of the Human Cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and ...]]></description><pubDate>Thu, 29 Jan 2015 10:20:24 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18053</guid></item><item><title>Rabbit polyclonal antibody directed against human cytomegalovirus protein gL</title><caseId>1260-B</caseId><link>http://icoregon.technologypublisher.com/technology/18052</link><description><![CDATA[Technology Overview
Rabbit polyclonal&nbsp;antisera against human cytomegalovirus (CMV) protein gL has been developed. This antisera&nbsp;is useful for research involving CMV. Please refer to the following publication for more information on this antisera. 

Aliquot provided: 0.5mL aliquots are provided. A minimum of three (3) aliquots of any combination of polyclonal antisera classified under OHSU Technology #1260 is required for each license/MTA.

Publication
Ryckman B.J., et al. Characterization of the Human Cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and end...]]></description><pubDate>Thu, 29 Jan 2015 10:20:24 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18052</guid></item><item><title>Rabbit polyclonal antibody directed against human cytomegalovirus protein gH</title><caseId>1260-A</caseId><link>http://icoregon.technologypublisher.com/technology/18051</link><description><![CDATA[
Technology Overview

Rabbit polyclonal&nbsp;antisera against human cytomegalovirus (CMV) protein gH has been developed. This antisera&nbsp;is useful for research involving CMV. Please refer to the following publication for more information on this antisera. 

Aliquot provided: 0.5mL aliquots are provided. A minimum of three (3) aliquots of any combination of polyclonal antisera classified under OHSU Technology #1260 is required for each license/MTA.

Publication

Ryckman B.J., et al. Characterization of the Human Cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and ...]]></description><pubDate>Thu, 29 Jan 2015 10:20:23 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18051</guid></item><item><title>Rabbit polyclonal antibodies directed against HCMV proteins gH, gL, UL128, UL130 and UL131</title><caseId>1260</caseId><link>http://icoregon.technologypublisher.com/technology/18033</link><description><![CDATA[
Technology Overview

Rabbit polyclonal antibodies against human cytomegalovirus (CMV) proteins gH, gL, UL128, UL130 and UL131 have been developed. These are useful for research involving CMV. Please refer to the following publication for more information on these antibodies.

Publication
Ryckman B.J. &ldquo;Characterization of the Human Cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.&rdquo; J. Virology (2008) 82(1):60-70. Link

Licensing Opportunity
The polyclonal antisera are available for non-exclusive licensing.]]></description><pubDate>Thu, 29 Jan 2015 10:20:05 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/18033</guid></item><item><title>A Facile Route to New and Old Cyclophanes from a Pnictogen-activated Self-Assembly Reaction</title><caseId>UO-14-55</caseId><link>http://icoregon.technologypublisher.com/technology/17954</link><description><![CDATA[The well-defined topology and high strain of cyclophanes has found utility in a number of applications including asymmetric catalysis, insulating plastics, and organic electronics.&nbsp; Unfortunately, the field of cyclophane chemistry has been hindered by a lack of high yielding and functional group tolerant preparative methods for their synthesis.&nbsp;&nbsp;

University of Oregon&rsquo;s inventors have developed a selective, high yielding alternative to traditional cyclophane synthesis by the use of a pnictogen additive to direct the self-assembly of discrete disulfide cyclophanes.&nbsp; Us...]]></description><pubDate>Fri, 16 Jan 2015 16:22:15 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/17954</guid></item><item><title>Synthesis of Solution Precursors From Aluminum and Gallium Bulk Minerals/Materials</title><caseId>UO-15-08</caseId><link>http://icoregon.technologypublisher.com/technology/17953</link><description><![CDATA[
The inventors developed novel methods for producing Keggin-like structures containing 13 metal ions ranging from all Gallium to all Aluminum to mixed metals of metal ions including combinations of Gallium, Aluminum, and Indium.&nbsp; These clusters are preorganized with the desired stoichiometry, which makes them ideal synthetic precursors for thin film production.&nbsp; They are exceptionally well suited for use in thin film transistors because they are optically clear and have improved electron mobility over existing deposited oxides.&nbsp; In addition, this novel synthetic method allows fo...]]></description><pubDate>Fri, 16 Jan 2015 16:20:09 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/17953</guid></item><item><title>Hazelnut 'Dorris'</title><caseId>OSU-12-17</caseId><link>http://icoregon.technologypublisher.com/technology/17665</link><description><![CDATA[Technology Description    
&lsquo;Dorris&rsquo; inherits a gene from the cultivar &lsquo;Gasaway&rsquo;, which confers a high level of resistance to EFB; trees of &lsquo;Dorris&rsquo; have remained mostly free of EFB, with only a few cases of small cankers under high disease pressure having been observed. Additionally, &lsquo;Dorris&rsquo; is resistant to bud mite (primarily Phytoptus avellanae Nal.). Its nuts mature at the same time as &lsquo;Barcelona&rsquo;, have 43% kernel by weight, and a nut yield efficiency that is significantly higher. As a result, &lsquo;Dorris&rsquo; displays versati...]]></description><pubDate>Wed, 10 Dec 2014 09:45:11 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/17665</guid></item><item><title>Hazelnut 'York'</title><caseId>OSU-12-18</caseId><link>http://icoregon.technologypublisher.com/technology/17664</link><description><![CDATA[Technology Description    
&lsquo;York&rsquo; carries the &lsquo;Gasaway&rsquo; gene, giving it resistance to EFB, with the exception of a few cases of small cankers under high disease pressure. Additionally, &lsquo;York&rsquo; is resistant to big bud mite (primarily Phytoptus avellanae Nal.), has very few nut defects, and its well-filled nuts are 46% kernel by weight. &lsquo;York&rsquo; expresses the incompatibility allele S21 in the pollen. Thus, pollen of &lsquo;York&rsquo; is compatible on most other hazelnut cultivars. &lsquo;York&rsquo; produces a multitude of catkins, copious quantities...]]></description><pubDate>Wed, 10 Dec 2014 09:39:39 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/17664</guid></item><item><title>Ultrasound needle guide</title><caseId>1917</caseId><link>http://icoregon.technologypublisher.com/technology/17602</link><description><![CDATA[
Summary

A two-part ultrasound needle guide system mounted on the end of an ultrasound probe which can be positioned at different locations and angles to guide a needle through the patient&rsquo;s skin and advanced to a preselected depth identified on the ultrasound.

Technology Overview

Some regional anesthetic procedures, such as paravertebral and lumbar plexus blocks, are difficult to perform using in-plane ultrasound needle guides due to the steep angle of needle entry for the procedure, altered trajectory of the needle, and needle depth issues. As a result, clinicians either do not use ...]]></description><pubDate>Wed, 26 Nov 2014 12:15:14 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/17602</guid></item><item><title>Apoptolidin-producing Strain Amycolatopsis sp. ICBB 8242</title><caseId>OSU-11-43</caseId><link>http://icoregon.technologypublisher.com/technology/14140</link><description>Background   
Apoptolidin is a macrolide. It was originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells. 

Technology Description    
A bacterial strain that produces a family of antibiotic compounds known as the apoptolidins. The predominant compound produced is apoptolidin A.


	Benefits include Increased Yield compared to published strains
	Applications include antibiotic and anticancer lead compound development


Opportunity   
Seeking a licensee, industry research sponsor, or collaborative research opportunity

Status    
Avail...</description><pubDate>Tue, 24 Dec 2013 10:57:45 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/14140</guid></item><item><title>Pharmaceutical compositions comprising napthamides</title><caseId>1699</caseId><link>http://icoregon.technologypublisher.com/technology/13535</link><description><![CDATA[SummaryResearchers at Oregon Health &amp; Science University have developed a first-in-class chemical series that regulates transcription activity of CREB via a novel mechanism of action and has the potential to address an unmet medical need for treatment of multiple cancers.&nbsp;Technology OverviewTargeted therapies have demonstrated the ability to effectively halt the progression of many cancers, leading to a global drug market of $93.75 billion in 2020, which is estimated to reach $162 billion by 2028 (Emergen Research, 2021). Cyclic-AMP response element binding protein (CREB) could be a p...]]></description><pubDate>Wed, 16 Oct 2013 16:32:40 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/13535</guid></item><item><title>Naphthamides as anticancer agents inhibiting CREB-mediated gene transcription</title><caseId>1295</caseId><link>http://icoregon.technologypublisher.com/technology/12422</link><description><![CDATA[
Summary

Researchers at Oregon Health &amp; Science University have developed a first-in-class chemical series that regulates transcription activity of CREB via a novel mechanism of action and has the potential to address an unmet medical need for treatment of multiple cancers.&nbsp;

Technology Overview

Targeted therapies have demonstrated the ability to effectively halt the progression of many cancers, leading to a global drug market of $93.75 billion in 2020, which is estimated to reach $162 billion by 2028 (Emergen Research, 2021). Cyclic-AMP response element binding protein (CREB) could...]]></description><pubDate>Wed, 01 May 2013 11:14:05 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/12422</guid></item><item><title>Cloroquine replacement drugs</title><caseId>1688</caseId><link>http://icoregon.technologypublisher.com/technology/11409</link><description><![CDATA[Summary
Researchers at Oregon Health &amp; Science University and at the Portland VA Medical Center have discovered and optimized a novel class of antimalarial compounds that are superior to the standard of care. 

Technology Overview
Malaria remains one of the deadliest diseases in the world today, as it has been for thousands of years. For each of the one million people killed each year, hundreds of millions more suffer from severe illness. The impact of malaria is particularly devastating in sub-Saharan Africa where its victims are primarily young children and pregnant women. This situation...]]></description><pubDate>Mon, 05 Nov 2012 08:09:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/11409</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Watkins</title><caseId>1221-S</caseId><link>http://icoregon.technologypublisher.com/technology/7237</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-S is 
the&nbsp;Watkins strain.
Inventor ProfileDr. Jay Nels...]]></description><pubDate>Tue, 31 May 2011 12:25:57 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7237</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Simpson</title><caseId>1221-R</caseId><link>http://icoregon.technologypublisher.com/technology/7236</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-R is 
the&nbsp;Simpson strain.
Inventor ProfileDr. Jay Nels...]]></description><pubDate>Tue, 31 May 2011 12:25:57 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7236</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Schmoe</title><caseId>1221-Q</caseId><link>http://icoregon.technologypublisher.com/technology/7235</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-Q is 
the&nbsp;Schmoe strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Tue, 31 May 2011 12:25:56 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7235</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Salvo</title><caseId>1221-P</caseId><link>http://icoregon.technologypublisher.com/technology/7234</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-P is 
the&nbsp;Salvo strain.
Inventor ProfileDr. Jay Nelson...]]></description><pubDate>Tue, 31 May 2011 12:25:56 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7234</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Powers</title><caseId>1221-O</caseId><link>http://icoregon.technologypublisher.com/technology/7233</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-O is 
the&nbsp;Powers strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Tue, 31 May 2011 12:25:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7233</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Phoebe</title><caseId>1221-N</caseId><link>http://icoregon.technologypublisher.com/technology/7232</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-N is 
the&nbsp;Phoebe strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Tue, 31 May 2011 12:25:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7232</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  New Rock</title><caseId>1221-M</caseId><link>http://icoregon.technologypublisher.com/technology/7231</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-M is 
the&nbsp;New Rock&nbsp;strain.
Inventor ProfileDr. Ja...]]></description><pubDate>Tue, 31 May 2011 12:25:54 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7231</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Martinez</title><caseId>1221-L</caseId><link>http://icoregon.technologypublisher.com/technology/7230</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-L is 
the&nbsp;Martinez strain.
Inventor ProfileDr. Jay Nel...]]></description><pubDate>Tue, 31 May 2011 12:25:54 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7230</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Lysistrata</title><caseId>1221-K</caseId><link>http://icoregon.technologypublisher.com/technology/7229</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-K is 
the&nbsp;Lysistrata strain.
Inventor ProfileDr. Jay N...]]></description><pubDate>Tue, 31 May 2011 12:25:53 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7229</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Lacey</title><caseId>1221-J</caseId><link>http://icoregon.technologypublisher.com/technology/7228</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-J is 
the&nbsp;Lacey strain.
Inventor ProfileDr. Jay Nelson...]]></description><pubDate>Tue, 31 May 2011 12:25:53 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7228</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Keone</title><caseId>1221-I</caseId><link>http://icoregon.technologypublisher.com/technology/7227</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-I is 
the&nbsp;Keone strain.
Inventor ProfileDr. Jay Nelson...]]></description><pubDate>Tue, 31 May 2011 12:25:52 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7227</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Harris</title><caseId>1221-H</caseId><link>http://icoregon.technologypublisher.com/technology/7226</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-H is 
the&nbsp;Harris strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Tue, 31 May 2011 12:25:52 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7226</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Gruden</title><caseId>1221-G</caseId><link>http://icoregon.technologypublisher.com/technology/7225</link><description><![CDATA[Technology Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-G is 
the&nbsp;Gruden strain.
Inventor ProfileDr. Jay Nelso...]]></description><pubDate>Tue, 31 May 2011 12:25:51 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7225</guid></item><item><title>Human cytomegalovirus (HCMV) clinical isolate strain:  Adinis</title><caseId>1221-A</caseId><link>http://icoregon.technologypublisher.com/technology/7219</link><description><![CDATA[
Technology 
Overview
Dr. Jay Nelson has a collection of HCMV 
strains available for licensing as a package or on an individual strain basis. 
The full list of strains which are available are listed under OHSU Technology 
#1221.&nbsp; These are all clinical isolates that are at early passage and have 
not been adapted to any cell type and should therefore retain both endothelial 
and epithelial cell tropism.&nbsp; These strains are useful for 
a variety of research applications in the field of HCMV.
The particular strain under OHSU 1221-A is the 
Adinis strain.
Inventor ProfileDr. Jay Nelson j...]]></description><pubDate>Tue, 31 May 2011 12:25:48 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7219</guid></item><item><title>Human cytomegalovirus  (HCMV) clinical isolate strains</title><caseId>1221</caseId><link>http://icoregon.technologypublisher.com/technology/7205</link><description><![CDATA[
Technology Overview

Dr. Jay Nelson has a collection of HCMV strains available for licensing as a package or on an individual strain basis.&nbsp; These are all clinical isolates that are at early passage and have not been adapted to any cell type and should therefore retain both endothelial and epithelial cell tropism.&nbsp; 

&nbsp;

The strains which are available include:

Adinis

Brown

Davis

Dement

Edding

Gerry 

Gruden

Harris

Keone

Lacey

Lysistrata

Martinez

New Rock

Phoebe

Powers

Salvo

Schmoe

Simpson

Watkins

These strains are useful for a variety of research applications...]]></description><pubDate>Tue, 31 May 2011 12:24:37 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/7205</guid></item><item><title>Fractal Interconnects for Neuro-Electronic Interfaces, Including Artificial Retinas</title><caseId>UO-11-01</caseId><link>http://icoregon.technologypublisher.com/technology/6947</link><description><![CDATA[
In conditions such as macular degeneration and retinitis pigmentosa, impaired vision&nbsp;is caused by a loss of function&nbsp;in the photoreceptor cells (the rods and cones),&nbsp;which lie&nbsp;within the retina at the back of the eye.&nbsp;However, the rest of the visual system, including the optic nerve and the visual processing centers in the brain, remain intact. If&nbsp;one can devise a viable work-around for the initial signal processing by the lost photoreceptors,&nbsp;one can replace the broken link in the system and restore vision.&nbsp;This is the aim of various researchers workin...]]></description><pubDate>Wed, 06 Apr 2011 10:21:31 GMT</pubDate><author>techtran@uoregon.edu</author><guid>http://icoregon.technologypublisher.com/technology/6947</guid></item><item><title>Flagmor transgenic mouse</title><caseId>1402</caseId><link>http://icoregon.technologypublisher.com/technology/5089</link><description><![CDATA[Summary
FLAGMOR transgenic mice provides an advantage to studying signal transduction of mu-opioid receptors (MOR) through the activation of potassium-ion channels, desensitization, and receptor trafficking.&nbsp;

Technology Overview
Mu-opioid receptors are a class of G-protein coupled receptors found primarily in the CNS and the GI system. The activation of MOR by opioids cause decreased perception of pain, decreased reaction to pain, and increased pain tolerance by inhibiting excitatory pathways.

The current mice express an epitope-tagged mu-opioid receptor (FLAGMOR) targeted to catecholam...]]></description><pubDate>Fri, 30 Apr 2010 15:34:55 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/5089</guid></item><item><title>BB19 cell line</title><caseId>1289</caseId><link>http://icoregon.technologypublisher.com/technology/5058</link><description><![CDATA[
Technology Overview
The current technology is an immortalized human brain capillary endothelial cell line named BB19.&nbsp; BB19 cells are derived from human brain endothelium and are immortalized with E6E7 genes of human papilloma virus.&nbsp; This cell line has been used to study cytoadherence of Plasmodium falciparum-infected erythrocytes in vitro.&nbsp; 

The cells partly maintain endothelial properties as shown by tubule formation with MatrigelTM as substrate.&nbsp; They express Factor VIII-related antigen and von Willebrand&rsquo;s factor.&nbsp; The cells exhibit cobblestone like morpho...]]></description><pubDate>Wed, 28 Apr 2010 15:32:08 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/5058</guid></item><item><title>C-Terminal Binding Protein (CtBP) single isoform lentiviral stable cell lines</title><caseId>1285</caseId><link>http://icoregon.technologypublisher.com/technology/5056</link><description><![CDATA[Technology Overview
These cell lines re-introduce CtBP wild type and functional mutant isoforms (both CtBP1 and 2) back into a CtBP1+2 null mouse embryonic fibroblast (MEF) line.&nbsp; These cells contain lentiviral-introduced protein encoding sequences that allow for stable expression of physiologic levels of CtBP isoforms under the tetracycline operon regulated promoter.&nbsp; This results in a cell in which either the wild type or mutant CtBP (1 or 2) is expressed in isolation, allowing study of gene specific regulatory events that are thought to be reliant upon CtBP.

These lines allow for...]]></description><pubDate>Wed, 28 Apr 2010 15:32:07 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/5056</guid></item><item><title>Bacterial artificial chromosome (BAC) clone containing the genome of human cytomegalovirus (HCMV) TR strain</title><caseId>1222</caseId><link>http://icoregon.technologypublisher.com/technology/5052</link><description><![CDATA[Technology Overview
The TR BAC was prepared from the TR clinical HCMV isolate. This virus is resistant to ganciclovir and cidofovir and lacks UL97 codons 591-594.&nbsp;The BAC clone was generated by substituting BAC DNA for the US2-US5 region of the TR genome. The TR strain infects almost any diploid endothelial or epithelial cell as well as macrophages.&nbsp; This strain is useful for studies on HCMV including genetic studies.

Publication
Murphy E, et al., Coding potential of laboratory and clinical strains of human cytomegalovirus. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14976-81.&nbsp...]]></description><pubDate>Wed, 28 Apr 2010 15:31:56 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/5052</guid></item><item><title>Glutathione Detection (RS-06 and -07)</title><caseId>STRR-03</caseId><link>http://icoregon.technologypublisher.com/technology/4963</link><description><![CDATA[Robert Strongin&nbsp;and his lab focus on dyes and fluorescing compounds 
for use in a variety of applications.&nbsp; Recently, they have developed new 
compounds for the colorometric detection of glutathione.&nbsp; The compounds are 
useful in detecting thiols generally, but can also be used to selectively detect 
glutathione, cysteine, and homocysteine.&nbsp; Current reported methods for 
thiol detection rely on non-specific redox chemistry, immunoassays, or 
derivitization with chromophores or fluorophores.&nbsp; These compounds meet a 
substantial need for detecting and distinguishing betw...]]></description><pubDate>Thu, 15 Apr 2010 12:25:01 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/4963</guid></item><item><title>Curriculum for HR Professionals to Support Employees with Children with Disabilities</title><caseId>BREE-01</caseId><link>http://icoregon.technologypublisher.com/technology/4792</link><description>Human Resources professionals sometimes lack knowledge in how best to provide support for their employees who have children with special needs. As this population of employees increases, more training and resources are needed. PSU's team from the Regional Research Institute has created and tested a set of effective materials for use with Human Resources professionals.</description><pubDate>Tue, 23 Mar 2010 15:16:44 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/4792</guid></item><item><title>PVP Potato 'Red Sunset' (Oregon Tri-State)</title><caseId>OSU-09-27</caseId><link>http://icoregon.technologypublisher.com/technology/4617</link><description><![CDATA[Technology Description   
Modoc vines mature slightly earlier than Red LaSoda, and are sensitive to metribuzin injury. Modoc is susceptible to most fungal diseases. It is susceptible to late blight foliar and tuber infection. Experience with seed increases indicate it is not particularly susceptible to virus diseases and expresses readily discernible foliar symptoms to PVY.

Features &amp; Benefits    


	High Fresh Market Quality
	High Marketable Yield
	Few Tuber Defects
	Bright Red Skin Color
	High Vitamin C Content


Background of Invention
Red Sunset is available for license through the Po...]]></description><pubDate>Thu, 11 Feb 2010 11:29:50 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/4617</guid></item><item><title>Plasmid IE86kd able to produce the human CMV IE86 protein</title><caseId>1266</caseId><link>http://icoregon.technologypublisher.com/technology/4500</link><description><![CDATA[Technology Overview
Technology # 1266, Plasmid IE86kd has been generated which can be utilized to produce the full length human cytomegalovirus (CMV) IE86 protein.&nbsp; 

Publication
Jupp R., et al.,&nbsp; Direct interaction of the Human Cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.&nbsp; J. Virology 1993 Sept;67(9):5595-5604. Link

Licensing Opportunity
The plasmid is available for non-exclusive licensing.

&nbsp;]]></description><pubDate>Thu, 28 Jan 2010 13:31:56 GMT</pubDate><author>techmgmt@ohsu.edu</author><guid>http://icoregon.technologypublisher.com/technology/4500</guid></item><item><title>Student Foreign Language Entrepreneurship</title><caseId>FISW-01</caseId><link>http://icoregon.technologypublisher.com/technology/3217</link><description><![CDATA[Fischer works with students enrolled in courses to enable them to learn business vocabulary and skills, all in a foreign language.&nbsp; This culminates in the release of products.&nbsp; Originally working only with German, Fischer and other faculty are now exploring how the course can be expanded to other languages.]]></description><pubDate>Thu, 23 Jul 2009 11:24:49 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3217</guid></item><item><title>Guilty Except For Insanity</title><caseId>HAAJ-01</caseId><link>http://icoregon.technologypublisher.com/technology/3216</link><description><![CDATA[Guilty Except for Insanity: Maddening journeys through an American Asylum&nbsp;is a documentary film directed by psychology professor Jan Haaken. The film follows the journeys of individuals over a period of a year who enter the Oregon State Hospital under the "guilty except for insanity" plea. Site of the filming of One Flew Over the Cuckoo's Nest, based on the novel by Ken Kesey, the Oregon State Hospital has been the focus of intense controversy, including charges by the U.S. Department of Justice of massive civil rights abuses of patients. This documentary tells a different side of the sto...]]></description><pubDate>Thu, 23 Jul 2009 11:24:49 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3216</guid></item><item><title>Best Practices for Data Analysis of Longitudinal Studies on Aging: A Practical Guide</title><caseId>NEWJ-01</caseId><link>http://icoregon.technologypublisher.com/technology/3215</link><description>As experts in the area, Newsom and colleagues are creating a new handbook on longitudinal studies on aging, designed for publication through a commercial publisher.</description><pubDate>Thu, 23 Jul 2009 11:24:48 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3215</guid></item><item><title>An Efficient Region-of-Interest Cropping Algorithm to Extract Small Regions of Video Out of Compressed Video Streams</title><caseId>FEN2-01</caseId><link>http://icoregon.technologypublisher.com/technology/3213</link><description><![CDATA[PSU researchers have created a technology which supports fast and efficient region-of-interest cropping from high-resolution video.&nbsp; We have a mechanism to compress a compliant video stream, and still allow cropping.]]></description><pubDate>Thu, 23 Jul 2009 11:24:48 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3213</guid></item><item><title>Modulating Activity of Calcium Release Channels</title><caseId>ABRJ-02</caseId><link>http://icoregon.technologypublisher.com/technology/3212</link><description><![CDATA[Using a new assay for drug development (see Abrj-01), PSU researchers have developed new compounds that may prove useful in the treatment of heart arrhythmia.
&nbsp;
Ventricular arrhythmias appear to be caused by a calcium leak from the sarcoplasmic reticulum in cardiac muscle, and arrhythmias often lead to heart failure.&nbsp; Drugs that prevent and treat arrhythmias often work by inhibiting this calcium leak.&nbsp;&nbsp; The PSU researchers have shown that their new compounds are a potent inhibitor of calcium leak in skeletal muscle, and will soon be testing the compounds in cardiac muscle...]]></description><pubDate>Thu, 23 Jul 2009 11:24:47 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3212</guid></item><item><title><![CDATA[Lecture and Q&A with Jane Jacobs]]></title><caseId>BALK-01</caseId><link>http://icoregon.technologypublisher.com/technology/3211</link><description>Video footage of a 2004 interview with Jane Jacobs, an American-born Canadian urbanist, writer and activist best known for The Death and Life of Great American Cities (1961), a powerful critique of the urban renewal policies of the 1950s in the United States.</description><pubDate>Thu, 23 Jul 2009 11:24:47 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3211</guid></item><item><title>Method and Apparatus for Sample Analysis</title><caseId>OBRR-01</caseId><link>http://icoregon.technologypublisher.com/technology/3210</link><description><![CDATA[PSU researchers have developed a novel way to collect, concentrate and analyze gas samples for analysis, primarily in environmental applications. By increasing pressure and performing analyses on a focused gas sample, this technology easily and cheaply enables continuous and real-time monitoring of air quality.&nbsp; Emission sources are more easily identified.&nbsp; An additional application is in metabolic studies or disease diagnosis.]]></description><pubDate>Thu, 23 Jul 2009 11:24:46 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3210</guid></item><item><title>Student Atlas of Oregon</title><caseId>BULT-01</caseId><link>http://icoregon.technologypublisher.com/technology/3199</link><description><![CDATA[Bulman and collaborators have developed a printed atlas of Oregon designed for students.&nbsp; Providing these printed atlases to users very inexpensively, they hope to improve students’ knowledge of Oregon geography.&nbsp; They also provide associated workshops around the State.]]></description><pubDate>Mon, 20 Jul 2009 16:52:09 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3199</guid></item><item><title>Method of Using and Producing Tropoelastin and Tropoelastic Biomaterials</title><caseId>WAMC-01</caseId><link>http://icoregon.technologypublisher.com/technology/3198</link><description><![CDATA[PSU researchers, in collaboration with the Oregon Biomedical Engineering Institute, have developed a new biomaterial that can be used to coat biomedical implants.&nbsp; The technology is currently licensed and under development. ]]></description><pubDate>Mon, 20 Jul 2009 16:52:08 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3198</guid></item><item><title>Fluorophore-Tagged Cisplatin</title><caseId>STRR-01</caseId><link>http://icoregon.technologypublisher.com/technology/3197</link><description><![CDATA[Many types of cancer, including carcinomas, lymphomas, sarcomas, and others, are treated with the chemotherapy agent Cisplatin.&nbsp; Based on the element platinum, cisplatin causes apoptosis in cancer cells by cross-linking their DNA.&nbsp; Like many chemotherapy agents, Cisplatin's effectiveness could be improved by better understanding how the body moves it around internally, so that it can be better targeted to cancer cells and thus protect normal cells from its effect.
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PSU researchers invented a fluorescently tagged cisplatin molecule that has been shown by collaborators at Oregon ...]]></description><pubDate>Mon, 20 Jul 2009 16:52:07 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3197</guid></item><item><title>Solution-Based Synthesis of Functional Graphene</title><caseId>YANM-04</caseId><link>http://icoregon.technologypublisher.com/technology/3196</link><description><![CDATA[PSU researchers have developed techniques to covalently attach single and multiple layers of graphene sheets on substrates. The graphene can subsequently be functionalized for use in nanobiosensor applications. Procedures are being developed for the solution-based synthesis and functionalization of graphene sheets from graphite in a way that is straightforward, and chemically adaptable.
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A wide range of range of graphene derivatives can be prepared, promising new materials for graphene based nano-composties, nano-biosensors, and nano-bioeletronics.
]]></description><pubDate>Mon, 20 Jul 2009 16:52:07 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3196</guid></item><item><title>Nitrogen Dioxide Gas Sensor</title><caseId>PRAS-02</caseId><link>http://icoregon.technologypublisher.com/technology/3194</link><description><![CDATA[PSU researchers have developed a new chemical gas sensor capable of detecting nitrogen dioxide (NO2) at levels less than 100ppb (two orders of magnitude more sensitive than current chemiluminescent based NOx sensors), having a dynamic linear range of parts per million to parts per billion, and a speed of detection of 60-120 seconds.
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Unlike existing chemical gas sensors, the PSU technology uses a special nanocomposite that undergoes selective linear changes in electrical resistance/conductance in the presence of NO2 in a near instant response.
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Prototypes of the sensor are under de...]]></description><pubDate>Mon, 20 Jul 2009 16:52:06 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3194</guid></item><item><title>Mono-Layer and Multi-Layer Nanowire Networks</title><caseId>JIAJ-02</caseId><link>http://icoregon.technologypublisher.com/technology/3193</link><description><![CDATA[The fabrication of nanoscale materials (by both bottom-up and top-down routes) has been driven by miniaturization of devices and the limitations of Si COMS technology.&nbsp; Research using one-dimensional nano-wires and nanotubes to fabricate nanodevices has demonstrated their potential applications, including field effect transistors, nano-biosensors, solar cells, and nano-generators; however, by and large these devices have been fabricated using a single nano-wire or an array of nano-wires assembled in a complicated, multi-step process.&nbsp; The mass-production of nano-structured devices re...]]></description><pubDate>Mon, 20 Jul 2009 16:52:06 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3193</guid></item><item><title>Nanoporous Membrane Protein Biomarker Detectors</title><caseId>PRAS-01</caseId><link>http://icoregon.technologypublisher.com/technology/3192</link><description><![CDATA[Disease assessment can be based on one or many biomarkers – a specific gene, protein, or other biological substance – that can be used to assess disease progress and aid in determining treatment. Unfortunately, biomarker-based measurements are often slow, expensive or otherwise impractical.
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PSU researchers have fabricated biomarker detectors with nano-pores. A nanoporous membrane of biomarker detectors can be sensitized to respond to a single target compound for increased accuracy, or different portions of the nano-membrane can be differently sensitized, allowing for more efficient dete...]]></description><pubDate>Mon, 20 Jul 2009 16:52:04 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3192</guid></item><item><title>Microelectrode Recording Analysis and Visualization for Improved Target Location</title><caseId>MCNJ-01</caseId><link>http://icoregon.technologypublisher.com/technology/3191</link><description>This is a neurosurgery tool to record and analyze microelectrode readings, resulting in more accurate targeting. In addition, these microelectrode visualization methods can be used in other fields of medicine where microelectrodes are used to determine neurological structures, such as deep brain stimulation for alleviating chronic pain, or seizure control.</description><pubDate>Mon, 20 Jul 2009 16:52:03 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3191</guid></item><item><title>Synthesis of Nanoscale Structures in Defined Locations</title><caseId>JIAJ-01</caseId><link>http://icoregon.technologypublisher.com/technology/3190</link><description><![CDATA[Since their discovery in 1991 by microscopist Sumio Iijima, carbon nanotubes have intrigued researchers with their structures and the applications enabled by their unique physical properties.&nbsp; Nanotubes exhibit high chemical resistance and mechanical strength, among other desirable physical properties.&nbsp; However, one ongoing challenge to exploiting these desirable properties is the difficulty associated with isolating and manipulating nanotubes for use as discrete device elements.
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PSU researchers have developed methods for directly synthesizing nanoscale structures in defined l...]]></description><pubDate>Mon, 20 Jul 2009 16:52:03 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/3190</guid></item><item><title>PVP Potato 'Umatilla Russet'</title><caseId>OSU-99-05</caseId><link>http://icoregon.technologypublisher.com/technology/3172</link><description><![CDATA[&nbsp;Technology Description Umatilla Russet, a moderately late maturing variety especially suitable for frozen French fry processing was jointly released by the Agricultural Experiment Stations of Oregon, Idaho, and Washington and the U.S. Department of Agriculture in 1998.&nbsp;Umatilla Russet was evaluated in irrigated trials in Oregon from 1988 to 1997, and in western regional trials from 1989 to 1991. Total yields were similar to those of Russet Burbank, but Umatilla Russetproduced higher marketable yields. In three years of regional trials at up to 13 locations in seven western states, U...]]></description><pubDate>Fri, 17 Jul 2009 14:42:20 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/3172</guid></item><item><title>Insight Resume™ (Copyright)</title><caseId>OSU-09-01</caseId><link>http://icoregon.technologypublisher.com/technology/2759</link><description><![CDATA[Technology Description    
The purpose of Insight Resume (IR) is to promote student success through more accurate assessment of student preparedness and academic potential. In addition to it&#39;s potential for making more accurate admissions decisions, this non-cognitive, holistic assessment provides OSU with more information on applicants, earlier than we&#39;ve ever had before. With this instrument developed by OSU, and the information it provides, we are able to proactively connect students to services that will help them be successful when they matriculate to OSU.]]></description><pubDate>Tue, 16 Jun 2009 11:09:27 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/2759</guid></item><item><title>PVP Potato 'Modoc' (Oregon Tri-State)</title><caseId>OSU-05-02</caseId><link>http://icoregon.technologypublisher.com/technology/2749</link><description>Technology Description   
Modoc (NDO4300-1R)is an early maturing, round to oval, red skinned clone suitable for fresh market use. It produces total yields slightly lower than those of Dark Red Norland and Red LaSoda but with a more desirable size profile, with higher yields of small, high-value tubers, and fewer culls. Tubers are round to oval, and seldom exhibit growth cracks or irregular shape common to Dark Red Norland and Red LaSoda. The tubers are a uniform bright skin color that does not fade in storage, and have shallow eye depth compared to Red LaSoda.Modoc tubers have specific gravity...</description><pubDate>Mon, 15 Jun 2009 10:49:27 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/2749</guid></item><item><title>PVP Potato 'Willamette' (Oregon Tri-State)</title><caseId>OSU-05-01</caseId><link>http://icoregon.technologypublisher.com/technology/2748</link><description>Technology Description   
Willamette (AO91812-1) is a high yielding round white variety with excellent chipping qualities. Tubers are similar in shape to those of Atlantic but average slightly smaller as shown by higher yields of tubers weighing less than 4 ounces, reduced tuber size may be due in part to later maturity. Willamette vines are medium large, vigorous and mature later than Atlantic. The flower color ranges from blue-purple violet inner corollas to light gray acumen, or petal tips. Willamette has typically shown fewer internal defects, especially brown center, hollow heart and inte...</description><pubDate>Mon, 15 Jun 2009 10:49:26 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/2748</guid></item><item><title>PVP Potato 'Wallowa Russet' (Oregon Tri-State)</title><caseId>OSU-01-27</caseId><link>http://icoregon.technologypublisher.com/technology/2745</link><description><![CDATA[Features &amp; Benefits    


	Produces much higher yield of U.S. No. 1s than Russet Burbank
	Excellent frozen processing characteristics
	Adapts to a wide range of soil and climatic conditions


Status    
Wallowa Russet is available for license through the Potato Variety Mangement Insitute, Inc. (PVMI). Please go to www.pvmi.org for more information about license details.]]></description><pubDate>Mon, 15 Jun 2009 10:49:25 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/2745</guid></item><item><title>PVP Potato 'Winema' (Oregon Tri-State)</title><caseId>OSU-00-17</caseId><link>http://icoregon.technologypublisher.com/technology/2743</link><description><![CDATA[Features &amp; Benefits    


	Excellent appearance with a bright red skin, shallow eyes and few defects
	Produces a high percentage of marketable tubers
	Susceptible to most fungal diseases and corky ringspot


Status    
Winema potatoes are available for license through the Potato Variety Management Institute, Inc. (PVMI). Please go to www.pvmi.org for more information about license details.]]></description><pubDate>Mon, 15 Jun 2009 10:49:24 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/2743</guid></item><item><title>PVP Potato 'Mazama' (Oregon Tri-State)</title><caseId>OSU-00-16</caseId><link>http://icoregon.technologypublisher.com/technology/2742</link><description>Technology Description   
Mazama (NDO2686-6R) is an early maturing clone with oval, bright red skinned tubers suitable for table use and the red-skinned creamer market. It produces lower total yields than Red LaSoda and Dark Red Norland, but similar marketable yields with a high percentage of small, high-value tubers, and significantly fewer culls. Mazama tubers are oval with uniformly bright red skin color that does not fade in storage, and have shallow eyes. They have higher specific gravity than Dark Red Norland and Red LaSoda. Internal defects, including hollow heart and brown center, and ...</description><pubDate>Mon, 15 Jun 2009 10:49:23 GMT</pubDate><author>advantage@oregonstate.edu</author><guid>http://icoregon.technologypublisher.com/technology/2742</guid></item><item><title>Screen for Redox Activity of Compounds</title><caseId>ABRJ-01</caseId><link>http://icoregon.technologypublisher.com/technology/2671</link><description><![CDATA[The design of new and effective drugs is a multi-billion dollar business, requiring great expense and extensive testing of drug candidate compounds.&nbsp; Obtaining a better understanding of the pharmacodynamics and mechanisms of action of drug candidates is an important and necessary step in optimizing any lead compound.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 

A property of increasing importance to some drugs' mechanism of action is their redox activity; in particular, a common factor in drugs aimed at affecting membrane bound transport proteins appears to be their ability to redox couple to th...]]></description><pubDate>Wed, 03 Jun 2009 14:09:21 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2671</guid></item><item><title>Shear-Force Ultrasonic Near-Field Microscope</title><caseId>LARA-01</caseId><link>http://icoregon.technologypublisher.com/technology/2670</link><description>
The Shear-Force Ultrasonic Near-Field Microscope (SUNM) is a nanometrology tool for surface and subsurface materials characterization, including the dynamic behavior of fluid-like mesoscopic films confined between two sliding solid boundaries. By mechanically exciting the film and detecting the resulting sound emitted, the elastic properties of the absorbed film itself (which can be altered by the sample's surface properties) and the mechanical response of the surrounding surface (which can be altered by the presence of subsurface defects) can be inferred.
As a surface metrology tool, the SUN...</description><pubDate>Wed, 03 Jun 2009 14:09:20 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2670</guid></item><item><title>New Dyes for Forensic Applications</title><caseId>STRR-02</caseId><link>http://icoregon.technologypublisher.com/technology/2645</link><description><![CDATA[Fingerprints are the most common and useful physical evidence for the apprehension and conviction of crime perpetrators.&nbsp; Reagents for the detection and enhancement of fingerprints are among the most useful tools in this regard.&nbsp; However, the available fluorogenic reagents for detecting and enhancing fingerprints left in blood have several associated challenges.&nbsp; For instance,&nbsp;some are generally unsuitable for dark and multi-colored substrates, while those that are (luminol, fluorescin) are not compatible with fixatives and their oxidation products or are not insoluble, lea...]]></description><pubDate>Wed, 27 May 2009 18:16:56 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2645</guid></item><item><title>Ambient Pressure NO2 Sensor</title><caseId>GEOL-01</caseId><link>http://icoregon.technologypublisher.com/technology/2614</link><description><![CDATA[The measurement of nitrogen dioxide (NO2) is important to both environmental monitoring and to research of flame, combustion, and surface chemistry.&nbsp; Current methods and devices operate at very low, sub-ambient pressures, requiring a substantial pumping system and limiting their usefulness in applications in higher pressure environments where direct and non-intrusive measurement of NO2 are desirable.
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PSU researchers have developed a selective and sensitive fluorescence based method and instrument for the direct measurement of NO2 at ambient pressure.&nbsp; The current prototype has...]]></description><pubDate>Tue, 26 May 2009 12:37:05 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2614</guid></item><item><title>Learner Web</title><caseId>REDS-01</caseId><link>http://icoregon.technologypublisher.com/technology/2613</link><description>The Learner Web is a learning support system providing structure and resources for adults who want to accomplish specific learning objectives. A learner can access the system through the Internet. In addition to on-line resources, the Learner Web integrates support services from existing local education programs, community based organizations, tutors, and telephone helpers. 
The Learner Web consists of a Web-based software system that is implemented regionally. The System is organized around Learning Plans. A Learning Plan is a set of steps structured around achieving an identified goal. For ...</description><pubDate>Tue, 26 May 2009 12:37:04 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2613</guid></item><item><title>Transparent Proof-of-Work Mechanism for Protecting Web Applications from Attack</title><caseId>FENW-01</caseId><link>http://icoregon.technologypublisher.com/technology/2611</link><description><![CDATA[PSU researchers have developed a transparent, backwards compatible proof-of-work system -- a defense mechanism that allows server owners to give client-specific challenges to those requesting access to network resources.&nbsp; All clients are provided tasks to perform prior to access being granted, with easier &amp; harder tasks available depending on the maliciousness of the client and the demand load on the server.]]></description><pubDate>Tue, 26 May 2009 12:37:04 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2611</guid></item><item><title>Cleaner, Less Expensive Amine Production</title><caseId>IWAD-01</caseId><link>http://icoregon.technologypublisher.com/technology/2610</link><description><![CDATA[PSU researchers and their collaborators have uncovered and engineered a new class of enzymes - the nitrile oxido reductases - that can aid in the chemical production of amines.
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In today's society, chemical manufacturing industries are facing increasing demands to practice environmentally conscientious methods and processes.&nbsp; Like all businesses, they also have a constant need to increase efficiency in their processes to maximize their bottom line.&nbsp; These two factors, among others, are driving a rapid increase in the use of enzymes in important industrial chemical transformatio...]]></description><pubDate>Tue, 26 May 2009 12:37:01 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2610</guid></item><item><title>Carbon Nanotube Multiplexers</title><caseId>ALRA-01</caseId><link>http://icoregon.technologypublisher.com/technology/2608</link><description><![CDATA[
Miniaturization of electronic and mechanical devices has permitted complex and sophisticated products to be realized inexpensively in compact packages.&nbsp; Such miniaturization has developed based primarily on advances in silicon wafer processing for circuit fabrication or micro-electromechanical systems.&nbsp; Unfortunately, at this point in time the incremental improvement of silicon wafer processing cannot lead to further significant enhancements in miniaturization.&nbsp; New nano-scale technologies that greatly reduce the size of circuits, actuators, and multiplexers will bring about th...]]></description><pubDate>Tue, 26 May 2009 12:37:00 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2608</guid></item><item><title>High Frequency Active Inductor</title><caseId>DAAR-01</caseId><link>http://icoregon.technologypublisher.com/technology/2607</link><description><![CDATA[An integrated inductor capable of operating at gigahertz (1 billion Hz) frequencies and above is a critical element in oscillators, filters, and wide-band low-noise amplifiers, (LNAs). The main applications are radio-frequency (RF) communication and high-speed data processing integrated circuits, such as those in cellular phones, wireless network cards, and broadband transceivers.
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Active integrated inductors are an alternative to passive inductors when the need for maximum selectivity (Q) prohibits the use of a passive inductor or when die area is limited.&nbsp; The key innovations of t...]]></description><pubDate>Tue, 26 May 2009 12:37:00 GMT</pubDate><author>iia@pdx.edu</author><guid>http://icoregon.technologypublisher.com/technology/2607</guid></item></channel></rss>