Search Results - therapeutics - neurology

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DRĪ±1-MOG-35-55 treatment of Traumatic Brain Injury
Treatment of traumatic brain injury is limited to medications to limit secondary damage to the brain, surgery to relieve pressure on the brain, and rehabilitation. The OHSU discovery uses a proprietary construct comprised of the human leukocyte antigen (HLA)-DRα1 domain linked covalently to mouse (m)MOG-35-55 peptide (DRα1-MOG-35-55 con...
Published: 3/20/2017   |   Inventor(s): Halina Offner-Vandenbark, Arthur Vandenbark
Keywords(s): Therapeutics, Therapeutics - Neurology
Category(s): Therapeutics
Small Molecule Inhibitors of the Mitochondrial Permeability Transition Pore (PTP)
Compositions for Treatment of Neurological and Oxidative Stress DisordersResearchers at Oregon Health & Science University and Kansas University discovered novel small molecule inhibitors of mitochondrial permeability transition pore (mtPTP) for treatment of cellular disorders associated with an over-accumulation of mitochondrial calcium or rea...
Published: 2/2/2015   |   Inventor(s): Michael Forte, Dennis Bourdette, Paolo Bernardi, Justina Sileikyte, Frank Schoenen, Sudeshna Roy
Keywords(s): Therapeutics, Therapeutics - Cardiology, Therapeutics - Neurology
Category(s): Therapeutics
POMC transgenic mice and neuron-specific promoter
Technology OverviewPOMC neurons of the hypothalamus are critical components of the neural circuitry controlling appetite, feeding, and metabolism. In addition they modulate the activity of other hypothalamic neurons which control reproduction, thyroid hormone levels, growth hormone secretion and neuroendocrine stress responses. Genetic evidence in ...
Published: 4/28/2010   |   Inventor(s): Malcolm Low, Marcelo Rubinstein, Flavio Silva De Souza
Keywords(s): Biological Materials, Biological Materials - Mice, Therapeutics, Therapeutics - Neurology
Category(s): Research Tools
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