Search Results - imaging+-+other

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Label-free fluorescent sensing of protease activity
­Summary The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. Technology Overview Dysregulated proteolytic activity is linked to many human diseases, including...
Published: 1/18/2023   |   Inventor(s): Adem Yildirim, Bruce Branchaud, Justin Plaut, Srivathsan Ranganathan, Sean Speese, Corey Dambacher, Sarah Barnhill, Emma Olson
Keywords(s): Diagnostics, Imaging, Imaging - Other, Research Tools
Category(s): Imaging, Research Tools, Diagnostics
Improved removal of projection artifacts in optical coherence tomographic angiography
­Summary The current algorithm improves projection artifacts removal for more accurate optical coherence tomographic angiography (OCTA) scans and better quantitative detection and monitoring of vascular abnormalities. Technology Overview Projection artifacts are one of the significant limitations of OCTA imaging, and a reliable projection-resolved...
Published: 12/6/2022   |   Inventor(s): Yali Jia, Jie Wang
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other
Category(s): Imaging, Diagnostics
Software for deep learning-based inference of biomarker distribution in cancer samples
Summary Multiplexed tissue imaging (MTI) is a powerful tool for cancer pathology, but it is also expensive, which has limited its availability for underserved communities, particularly in the developing world. The current software uses hematoxylin & eosin (H&E) staining, which is more widely available, to predict oncology biomarker distribution,...
Published: 12/2/2022   |   Inventor(s): Young Hwan Chang, Erik Burlingame, Geoffrey Schau, Elliot Gray
Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Diagnostics, Software
Fully-automated diabetic retinopathy (DR) screening based on OCT and its angiography
Summary The current technology provides a framework for a fully-automated deep-learning-based diabetic retinopathy screening that relies solely on optical coherence tomography (OCT) and its angiography, without the need for fundus photography or time-intensive clinical evaluation. Technology Overview Diabetic retinopathy (DR) is a leading cause of...
Published: 10/14/2022   |   Inventor(s): Yali Jia, Pengxiao Zang
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Diagnostics, Imaging, Software
OCT-based artificial intelligence for irregular cornea classification
Summary ­The current technology provides for an OCT-based artificial intelligence (AI) algorithm to improve classification and diagnosis between common corneal shape abnormalities including forme fruste (pre-clinical) keratoconus (FFK), contact lens related warpage, dry eye disease, and Fuch’s endothelial dystrophy. Technology Overview Keratoconus...
Published: 7/14/2022   |   Inventor(s): David Huang, Yan Li, Elias Pavlatos, Xubo Song
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other
Category(s): Diagnostics, Imaging
Sensorless adaptive optics (AO) control method for OCT/OCT-angiography retinal imaging
Summary Researchers have developed an improved method of adaptive optics for OCT/OCT-angiography retinal scanning that is sensorless and allows for optical aberrations correction without considerably increasing scan times. Technology Overview Adaptive optics OCT (AO-OCT) allows for high lateral resolution imaging of the retinal tissue and blood flow...
Published: 1/19/2022   |   Inventor(s): Yifan Jian, Acner Camino Benech
Keywords(s): Imaging, Imaging - Other
Category(s): Imaging
Algorithm for assessing retinal fluid volume using OCT/OCTA
SummaryMeasurement of retinal fluid volume could improve diagnosis and tracking of diabetic macular edema (DME); however, current methods rely on two-dimensional measurements, which have limited accuracy. The current technology uses volumetric OCT/OCT angiography scans to provide a three-dimensional and more accurate retinal fluid volume, potentially...
Published: 10/29/2021   |   Inventor(s): Yali Jia, Yukun Guo
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other, Software, Software - Other
Category(s): Diagnostics, Imaging, Software
Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications
SummaryRhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...
Published: 7/1/2022   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Quantification of vascular abnormality with OCT angiography
Summary Current OCT techniques are limited in their ability to accurately detect vasculature changes, and patients with retinal vascular diseases often require more invasive intravenous contrast dye-based angiography procedures. The current technology is an OCT-based non-injection, dye-free method that allows for 3D visualization of superimposed structural...
Published: 9/23/2022   |   Inventor(s): David Huang, Yali Jia
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software
Category(s): Diagnostics, Imaging, Software
Forward scanning vitrectomy OCT microprobe
SummaryThe practical employment of OCT probes in surgeries of solid organs or internal cavities has been limited by the lack of miniature forward-scanning probes. Dr. David Huang and colleagues have developed a small forward-scanning OCT vitrectomy probe that would allow for the incorporation of OCT into probe-guided procedures for a variety of organs.Technology...
Published: 7/20/2022   |   Inventor(s): David Huang, Yimin Wang, James Fujimoto, Chen Lu, David Wilson, John Stout
Keywords(s): Device, Device - Surgical, Imaging, Imaging - Other
Category(s): Device, Imaging
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