Search Results - imaging+-+other

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Artificial Intelligence-Assisted Projection-Resolved Optical Coherence Tomographic Angiography (aiPR-OCTA)

Summary The current artificial intelligence algorithm removes projection artifacts in optical coherence tomographic angiography images and improves the signal-to-noise ratio. Technology Overview A major limitation of optical coherence tomography angiography (OCTA) are image artifacts, particularly projection artifacts, which make the detection of...

Published: 2/2/2024 | Inventor(s): Yali Jia, Jie Wang

Keywords(s): Imaging, Imaging - Other

Category(s): Imaging

An OCT method to improve scleral lens fitting

Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...

Published: 1/5/2024 | Inventor(s): David Huang, Yan Li, Clara Llorens Quintana

Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Imaging, Software

Label-free fluorescent sensing of protease activity

Summary The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. Technology Overview Dysregulated proteolytic activity is linked to many human diseases, including...

Published: 9/27/2023 | Inventor(s): Adem Yildirim, Bruce Branchaud, Justin Plaut, Srivathsan Ranganathan, Sean Speese, Corey Dambacher, Sarah Barnhill, Emma Olson

Keywords(s): Diagnostics, Imaging, Imaging - Other, Research Tools

Category(s): Imaging, Research Tools, Diagnostics

Improved removal of projection artifacts in optical coherence tomographic angiography

Summary The current algorithm improves projection artifacts removal for more accurate optical coherence tomographic angiography (OCTA) scans and better quantitative detection and monitoring of vascular abnormalities. Technology Overview Projection artifacts are one of the significant limitations of OCTA imaging, and a reliable projection-resolved...

Published: 9/27/2023 | Inventor(s): Yali Jia, Jie Wang

Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other

Category(s): Imaging, Diagnostics

Software for deep learning-based inference of biomarker distribution in cancer samples

Summary Multiplexed tissue imaging (MTI) is a powerful tool for cancer pathology, but it is also expensive, which has limited its availability for underserved communities, particularly in the developing world. The current software uses hematoxylin & eosin (H&E) staining, which is more widely available, to predict oncology biomarker distribution,...

Published: 9/27/2023 | Inventor(s): Young Hwan Chang, Erik Burlingame, Geoffrey Schau, Elliot Gray

Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Diagnostics, Software

Fully-automated diabetic retinopathy (DR) screening based on OCT and its angiography

Summary The current technology provides a framework for a fully-automated deep-learning-based diabetic retinopathy screening that relies solely on optical coherence tomography (OCT) and its angiography, without the need for fundus photography or time-intensive clinical evaluation. Technology Overview Diabetic retinopathy (DR) is a leading cause of...

Published: 10/14/2022 | Inventor(s): Yali Jia, Pengxiao Zang

Keywords(s): Diagnostics, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Diagnostics, Imaging, Software

Sensorless adaptive optics (AO) control method for OCT/OCT-angiography retinal imaging

Summary Researchers have developed an improved method of adaptive optics for OCT/OCT-angiography retinal scanning that is sensorless and allows for optical aberrations correction without considerably increasing scan times. Technology Overview Adaptive optics OCT (AO-OCT) allows for high lateral resolution imaging of the retinal tissue and blood flow...

Published: 1/19/2022 | Inventor(s): Yifan Jian, Acner Camino Benech

Keywords(s): Imaging, Imaging - Other

Category(s): Imaging

Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications

Summary Rhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...

Published: 9/21/2023 | Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano

Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents

Category(s): Imaging, Research Tools

Quantification of vascular abnormality with OCT angiography

Summary Current OCT techniques are limited in their ability to accurately detect vasculature changes, and patients with retinal vascular diseases often require more invasive intravenous contrast dye-based angiography procedures. The current technology is an OCT-based non-injection, dye-free method that allows for 3D visualization of superimposed structural...

Published: 8/23/2023 | Inventor(s): David Huang, Yali Jia

Keywords(s): Diagnostics, Imaging, Imaging - Other, Software

Category(s): Diagnostics, Imaging, Software

Forward scanning vitrectomy OCT microprobe

Summary The practical employment of OCT probes in surgeries of solid organs or internal cavities has been limited by the lack of miniature forward-scanning probes. Dr. David Huang and colleagues have developed a small forward-scanning OCT vitrectomy probe that would allow for the incorporation of OCT into probe-guided procedures for a variety of organs. Technology...

Published: 9/26/2023 | Inventor(s): David Huang, Yimin Wang, James Fujimoto, Chen Lu, David Wilson, John Stout

Keywords(s): Device, Device - Surgical, Imaging, Imaging - Other

Category(s): Device, Imaging

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