Search Results - imaging

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Label-free fluorescent sensing of protease activity
­Summary The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. Technology Overview Dysregulated proteolytic activity is linked to many human diseases, including...
Published: 1/18/2023   |   Inventor(s): Adem Yildirim, Bruce Branchaud, Justin Plaut, Srivathsan Ranganathan, Sean Speese, Corey Dambacher, Sarah Barnhill, Emma Olson
Keywords(s): Diagnostics, Imaging, Imaging - Other, Research Tools
Category(s): Imaging, Research Tools, Diagnostics
Improved removal of projection artifacts in optical coherence tomographic angiography
­Summary The current algorithm improves projection artifacts removal for more accurate optical coherence tomographic angiography (OCTA) scans and better quantitative detection and monitoring of vascular abnormalities. Technology Overview Projection artifacts are one of the significant limitations of OCTA imaging, and a reliable projection-resolved...
Published: 12/6/2022   |   Inventor(s): Yali Jia, Jie Wang
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other
Category(s): Imaging, Diagnostics
Framework for 3D retinal pathology detection by OCT/OCT-angiography
​​Summary The current technology provides a platform for a fully-automated OCT-based 3D detection of retinal pathologies with significantly reduced processing requirements, which could allow for more wide-spread adoption of OCT/OCT-angiography 3D analysis. Technology Overview Optical coherence tomography (OCT) and its angiography can be used to provide...
Published: 10/14/2022   |   Inventor(s): Yali Jia, Shaohua Pi
Keywords(s): Diagnostics, Imaging, Software, Software - Diagnostic/Detection
Category(s): Diagnostics, Imaging, Software
Fully-automated diabetic retinopathy (DR) screening based on OCT and its angiography
Summary The current technology provides a framework for a fully-automated deep-learning-based diabetic retinopathy screening that relies solely on optical coherence tomography (OCT) and its angiography, without the need for fundus photography or time-intensive clinical evaluation. Technology Overview Diabetic retinopathy (DR) is a leading cause of...
Published: 10/14/2022   |   Inventor(s): Yali Jia, Pengxiao Zang
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Diagnostics, Imaging, Software
Universal nanoprobes for imaging and treatment of cancer
Summary Medical imaging is currently incapable of detecting very small tumors and there is a need for new contrast agents that allow for earlier detection of cancers. The current technology is a self-assembled nanoprobe that specifically accumulates in a broad range of solid tumors to enable 1) high-resolution imaging for earlier cancer detection...
Published: 8/16/2022   |   Inventor(s): Adem Yildirim, Jared Fischer, Bruce Branchaud
Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Therapeutics, Therapeutics - Cancer
Category(s): Diagnostics, Imaging, Therapeutics
OCT-based artificial intelligence for irregular cornea classification
Summary ­The current technology provides for an OCT-based artificial intelligence (AI) algorithm to improve classification and diagnosis between common corneal shape abnormalities including forme fruste (pre-clinical) keratoconus (FFK), contact lens related warpage, dry eye disease, and Fuch’s endothelial dystrophy. Technology Overview Keratoconus...
Published: 7/14/2022   |   Inventor(s): David Huang, Yan Li, Elias Pavlatos, Xubo Song
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other
Category(s): Diagnostics, Imaging
Device and method for creating Gaussian electron beams
University of Oregon Researchers: Benjamin McMorran Patent: 9,240,255 issued 1/19/2016 (UO-13-07) Device and Method for Creating Gaussian Electron Beams. Technology Background/Definition of Problem: Electron beams used in instrumentation such as scanning electron microscopes, transmission electron microscopes, microprobes, etc. exhibit numerous...
Published: 6/10/2022   |   Inventor(s): Benjamin McMorran
Category(s): Engineering, Imaging, Materials Science, Nanoscience & Microtechnologies, Physical Science, Research Tools
Deterministic Quantum Emitter Formation in Hexagonal Boron Nitride via Controlled Edge Creation
­ Technology Background: Sources of single photons are a key component of many emerging quantum information technologies such as quantum computation, communication, and sensing. However, the more commonly used quantum emitters (QEs), such as cold atoms and spontaneous parametric down-conversion sources, require complex setups that limit their...
Published: 6/10/2022   |   Inventor(s): Benjamin Aleman
Keywords(s): Science
Category(s): Chemistry, Engineering, Imaging, Materials Science, Nanoscience & Microtechnologies, Communications, Physical Science
Fluorinated CPPs
HEADLINE: Groundbreaking fluorescent marker technology using nanohoops Description: Biocompatible fluorescent molecules are essential for observing complex biological events in real time. Our groundbreaking fluorescent marker technology gives researchers a new kind of optical tag to use in biotechnology, biomedical sciences and chemical biology research....
Published: 5/2/2022   |   Inventor(s): Ramesh Jasti, Jeff Van Raden, Erik Leonhardt
Category(s): Chemistry, Imaging, Materials Science, Nanoscience & Microtechnologies, Physical Science
Fluorescent Halogen Bonding Arylethynyl Scaffolds For Anion Recognition
­The synthesis of new molecules designed to bind or sense and report the presence of a particular substrate is an area of chemistry that is attracting attention. There exists a general lack of ligand-specific host molecules, such as specific hosts for toxic ions and small molecules of interest. There also is a dearth of specific hosts that report...
Published: 5/2/2022   |   Inventor(s): Darren Johnson, Michael Haley, Jessica Lohrman
Keywords(s): Science
Category(s): Chemistry, Agricultural, Imaging, Materials Science, Nanoscience & Microtechnologies, Physical Science
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