Search Results - imaging

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Fluorophores for multicolor microscopy
SummaryMulticolor microscopy can be used to localize and visualize complex subcellular systems, but current systems are often limited in the number of fluorophores that can be imaged simultaneously. Oregon Health & Science University researchers have developed novel fluorophores that increase the number of channels and subcellular structures that...
Published: 12/2/2021   |   Inventor(s): Summer Dowell (Gibbs), Amy Bittel, Xiaolin Nan
Keywords(s): Imaging, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Algorithm for assessing retinal fluid volume using OCT/OCTA
SummaryMeasurement of retinal fluid volume could improve diagnosis and tracking of diabetic macular edema (DME); however, current methods rely on two-dimensional measurements, which have limited accuracy. The current technology uses volumetric OCT/OCT angiography scans to provide a three-dimensional and more accurate retinal fluid volume, potentially...
Published: 10/29/2021   |   Inventor(s): Yali Jia, Yukun Guo
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other, Software, Software - Other
Category(s): Diagnostics, Imaging, Software
Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications
SummaryRhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...
Published: 10/27/2021   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Quantification of Vascular Abnormality with OCT Angiography
SummaryCurrent OCT techniques are limited in their ability to accurately detect vasculature changes, and patients with retinal vascular diseases often require more invasive intravenous contrast dye-based angiography procedures. The current technology is an OCT-based non-injection, dye-free method that allows for 3D visualization of superimposed structural...
Published: 8/3/2021   |   Inventor(s): David Huang, Yali Jia
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software
Category(s): Diagnostics, Imaging, Software
Forward scanning vitrectomy OCT microprobe
SummaryThe practical employment of OCT probes in surgeries of solid organs or internal cavities has been limited by the lack of miniature forward-scanning probes. Dr. David Huang and colleagues have developed a small forward-scanning OCT vitrectomy probe that would allow for the incorporation of OCT into probe-guided procedures for a variety of organs.Technology...
Published: 7/19/2021   |   Inventor(s): David Huang, Yimin Wang, James Fujimoto, Chen Lu, David Wilson, John Stout
Keywords(s): Device, Device - Surgical, Imaging, Imaging - Other
Category(s): Device, Imaging
Systems and Methods for Retinal Capillary Oximetry
SummaryA system and method to assess the blood oxygen saturation in retinal vessels and capillaries, in high resolution. This invention can quantify the oxygen saturation in a single capillary using a non-invasive and dye-free technique.Technology OverviewAltered oxygen supply is thought to be a critical factor underlying many retinal disorders that...
Published: 6/9/2021   |   Inventor(s): Yali Jia, Shaohua Pi
Keywords(s): Imaging - Other
Category(s): Imaging
Visual Field Simulation Using OCT and OCT Angiography
Summary Preventing glaucoma disease progression requires regular monitoring and timely treatment. However, current assessment of visual field loss is subjective and can be unreliable for monitoring small progressive vision loss. Accordingly, Dr. David Huang et al. developed an OCTA test that produces simulated visual fields. The test provides a more...
Published: 6/4/2021   |   Inventor(s): David Huang, Ou Tan, Liang Liu
Keywords(s): Device, Engineering & Physical Science, Imaging, Software
Category(s): Imaging, Device, Software, Engineering
Novel Device for Ultrasound-assisted IV placement
SummaryIntravenous (IV) lines are placed over 200 million times per year, but difficulties occur in securing proper placement in a large percentage of cases, approximately 20-30%. Oregon Health & Science University researchers have developed a novel device to allow for easier execution of ultrasound-guided IV placement. Technology OverviewIV lines...
Published: 5/19/2021   |   Inventor(s): Matthew Hansen
Keywords(s): Device, Device - Other, Imaging - Acoustic, Imaging - Other
Category(s): Device, Imaging
Tomographic bright field imaging (TBFI)
SummaryTomographic bright field image analysis enables the three-dimensional measurement of engineered and biological specimens without the requirement of sample labeling or expensive specialized optical equipment. This novel software offers the unique advantage of true quantitative image analysis of factors like mass and density and could provide a...
Published: 4/27/2021   |   Inventor(s): Owen McCarty, Kevin Phillips, Steven Jacques
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Other, Software, Software - Other
Category(s): Imaging, Software, Research Tools
Self-tracking real-time high-resolution wide-field OCT angiography (OCTA)
SummaryOptical coherence tomographic angiography (OCTA) provides superior resolution and volumetric data compared to fluorescein angiography, but this 3D technology requires motion artifact compensation caused by movements during the scan. Oregon Health & Science University researchers have developed a method to suppress motion artifacts caused...
Published: 4/13/2021   |   Inventor(s): Yali Jia, Xiang Wei
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Software, Imaging
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