Search Results - imaging

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Novel Second Generation Fluorescent Dyes For In Vivo Nerve-specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed a second generation of novel, nerve-specific fluorescent dyes for diagnostic use in image-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visual identification of nerves. Technology OverviewDuri...
Published: 1/4/2019   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Adipose-specific fluorescent dyes for in vivo imaging
Technology SummaryResearchers at Oregon Health & Science University have developed novel adipose-specific fluorescent dyes for use in image-guided surgery of anatomical structures, such as nerves, that are surrounded by adipose tissue. The generated fluorophores exhibit reduced nerve accumulation, and demonstrate higher adipose-to-nerve and adi...
Published: 1/4/2019   |   Inventor(s): Jesse Korber, Connor Barth, Summer Dowell (Gibbs)
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Novel Fluorescent Dyes for In Vivo Nerve-Specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed novel, small molecule near infrared (NIR) nerve-specific fluorophores for diagnostic use in fluorescence-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visualization of nerves during surgical pr...
Published: 11/8/2018   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Contrast-Enhanced Magnetic Resonance Imaging for Detection and Quantification of Fibrosis in Human Myocardium
Technology OverviewMyocardial fibrosis is a morphologic change common to multiple cardiac disease conditions. In addition to replacement (scar) fibrosis, there is increasing recognition of interstitial (reactive) fibrosis acting as an important player in structural remodeling of the diseased heart, as well as the genesis of fatal arrhythmia leading...
Published: 3/16/2018   |   Inventor(s): Michael Jerosch-Herold, Sumeet Chugh
Keywords(s): Diagnostics, Diagnostics - Cardiology, Imaging, Imaging - MRI, Software
Category(s): Diagnostics
Algorithm For Automated Detection of Melanoma
Technology Overview Comprehensive diagnosis of melanoma typically requires both reliable histopathology and the trained eye of a clinician for assessment. With optical (as opposed to physical) sectioning of tissue and OHSU created software to process confocal images, it is possible to distinguish the diagnostic traits of malignancy, such as the...
Published: 11/9/2017   |   Inventor(s): Daniel Gareau, Ricky Hennessy, Steven Jacques
Keywords(s): Device, Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Other, Software
Category(s): Diagnostics
T2* Mapping for quantitative assessment of placental function and oxygenation
Despite recent focus, including the announcement of the NIH Human Placenta Project, on placental health and function as a primary driver of fetal growth and development, current in vivo identification and assessment of abnormal placentation is limited. This MRI protocol and modeling methodology, which uses an endogeneous contrast agent and therefor...
Published: 3/14/2016   |   Inventor(s): Matthias Schabel, Antonio Frias, Christopher Kroenke
Keywords(s): Diagnostics, Imaging, Imaging - MRI
Category(s): Diagnostics, Imaging
Super-Resolution Image Analysis for 2D/3D Reconstruction
A professor at Oregon Health & Science University has developed a novel algorithm that can be incorporated into digital imaging systems to create super-resolution (SR) images beyond the camera Nyquist frequency. The broad utility of the algorithm enables sharper, more detailed images to be reconstructed from sensitive imaging instruments such a...
Published: 9/16/2015   |   Inventor(s): James (zhi) Chen
Keywords(s): Imaging, Software - Diagnostic/Detection
Category(s): Imaging, Software, Research Tools
3-D directional blood perfusion mapping by use of optical coherence angiography in vivo OCT
Technology OverviewOHSU has developed technology for optical coherence tomography (OCT) imaging that extends OCT’s depth imaging range, enables real time flow imaging, and further enables optical coherence angiography. In vivo three-dimensional mapping of biologic tissue and vasculature is a challenging proposition due to the highly-scatteri...
Published: 1/29/2015   |   Inventor(s): Ruikang Wang
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other, Software
Category(s): Diagnostics, Imaging, Software
Software for Real-space Refinement of Macromolecular Structures: Software to Improve the Fit of Biomolecular Models to Experimental Images
Value Proposition: Researchers at Oregon Health & Science University have developed software that utilizes real-space refinement to optimize atomic models of macromolecules fit into experimental electron density maps obtained either by x-ray crystallography or 3D electron microscopy. Real-space refinement optimizes the agreement between d...
Published: 5/1/2013   |   Inventor(s): Michael Chapman, Andrew Trzynka, Brynmor Chapman
Keywords(s): Imaging, Research Tools, Research Tools - Other, Software, Software - Bioinformatics, Software - Other
Category(s): Software
Method and device for non-invasive analyte measurement
Technology OverviewPeople with diabetes can significantly reduce the risk of complications associated with disease by actively monitoring their blood glucose levels. The current standard method of monitoring blood glucose levels involves painful finger sticks and many diabetic patients fail to actively manage their glucose levels for the primary r...
Published: 4/8/2010   |   Inventor(s): Peter Jacobs, Dawn Konrad-Martin, Eric Wan
Keywords(s): Device, Imaging, Imaging - Acoustic, Software
Category(s): Device
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