Search Results - imaging

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Algorithm for assessing retinal fluid volume using OCT/OCTA
SummaryMeasurement of retinal fluid volume could improve diagnosis and tracking of diabetic macular edema (DME); however, current methods rely on two-dimensional measurements, which have limited accuracy. The current technology uses volumetric OCT/OCT angiography scans to provide a three-dimensional and more accurate retinal fluid volume, potentially...
Published: 10/29/2021   |   Inventor(s): Yali Jia, Yukun Guo
Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other, Software, Software - Other
Category(s): Diagnostics, Imaging, Software
Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications
SummaryRhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...
Published: 10/27/2021   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Quantification of Vascular Abnormality with OCT Angiography
SummaryCurrent OCT techniques are limited in their ability to accurately detect vasculature changes, and patients with retinal vascular diseases often require more invasive intravenous contrast dye-based angiography procedures. The current technology is an OCT-based non-injection, dye-free method that allows for 3D visualization of superimposed structural...
Published: 8/3/2021   |   Inventor(s): David Huang, Yali Jia
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software
Category(s): Diagnostics, Imaging, Software
Forward scanning vitrectomy OCT microprobe
SummaryThe practical employment of OCT probes in surgeries of solid organs or internal cavities has been limited by the lack of miniature forward-scanning probes. Dr. David Huang and colleagues have developed a small forward-scanning OCT vitrectomy probe that would allow for the incorporation of OCT into probe-guided procedures for a variety of organs.Technology...
Published: 7/19/2021   |   Inventor(s): David Huang, Yimin Wang, James Fujimoto, Chen Lu, David Wilson, John Stout
Keywords(s): Device, Device - Surgical, Imaging, Imaging - Other
Category(s): Device, Imaging
Visual Field Simulation Using OCT and OCT Angiography
Summary Preventing glaucoma disease progression requires regular monitoring and timely treatment. However, current assessment of visual field loss is subjective and can be unreliable for monitoring small progressive vision loss. Accordingly, Dr. David Huang et al. developed an OCTA test that produces simulated visual fields. The test provides a more...
Published: 6/4/2021   |   Inventor(s): David Huang, Ou Tan, Liang Liu
Keywords(s): Device, Engineering & Physical Science, Imaging, Software
Category(s): Imaging, Device, Software, Engineering
Tomographic bright field imaging (TBFI)
SummaryTomographic bright field image analysis enables the three-dimensional measurement of engineered and biological specimens without the requirement of sample labeling or expensive specialized optical equipment. This novel software offers the unique advantage of true quantitative image analysis of factors like mass and density and could provide a...
Published: 4/27/2021   |   Inventor(s): Owen McCarty, Kevin Phillips, Steven Jacques
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Other, Software, Software - Other
Category(s): Imaging, Software, Research Tools
Self-tracking real-time high-resolution wide-field OCT angiography (OCTA)
SummaryOptical coherence tomographic angiography (OCTA) provides superior resolution and volumetric data compared to fluorescein angiography, but this 3D technology requires motion artifact compensation caused by movements during the scan. Oregon Health & Science University researchers have developed a method to suppress motion artifacts caused...
Published: 4/13/2021   |   Inventor(s): Yali Jia, Xiang Wei
Keywords(s): Diagnostics, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Software, Imaging
Nanoparticle ultrasound contrast agents with high acoustic activity
SummaryContrast-enhanced ultrasound allows for low-cost minimally-invasive imaging; however, the size of typical contrast reagents prevents them from penetrating tumors thereby limiting their utility for cancer diagnostic and therapeutic purposes (theranostics). Oregon Health & Science University (OHSU) researchers have developed novel nanoparticle...
Published: 2/24/2021   |   Inventor(s): Adem Yildirim, Jose Montoya Mira, Sadik Esener, Stuart Ibsen
Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Acoustic, Research Tools, Therapeutics
Category(s): Diagnostics, Imaging, Nanoscience & Microtechnologies, Research Tools, Therapeutics
Novel albumin binder for improving the targeting efficacy of diagnostic or therapeutic reagents
Technology Summary Albumin binders have been developed to improve tumor uptake of therapeutic radioisotopes (radiopeptides) by prolonging radiopeptide blood circulation. However, use of these albumin binders also results in an increased uptake of radiopeptide in healthy organs, negating the benefits of the treatment. Researchers at Oregon Health...
Published: 1/28/2021   |   Inventor(s): Dexing Zeng, Lingyi Sun, Zhonghan Li
Keywords(s): Diagnostics - Cancer, Imaging, Therapeutics - Cancer
Category(s): Therapeutics, Chemical, Imaging
Novel Fluorescent Dyes for In Vivo Nerve-Specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed novel, small molecule near infrared (NIR) nerve-specific fluorophores for diagnostic use in fluorescence-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visualization of nerves during surgical procedures,...
Published: 9/16/2020   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
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