Search Results - srivathsan+ranganathan

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Summary The current technology is an improved method of antibody conjugation that allows for rapid and scalable antibody labeling, which could be utilized for a number of omics techniques and other antibody-based platforms. Technology Overview In order to label and functionalize antibodies, direct or secondary conjugations are typically employed....

Published: 11/2/2023 | Inventor(s): Kai Tao, Srivathsan Ranganathan, Emine (Sila) Ozdemir, Matthew Rames, Michael Brasino, Mingchong Dai, Gulsu Sener Yildrim

Keywords(s): Research Tools

Category(s): Research Tools, Proteomics

De novo peptide sequencer

Summary De novo protein-sequencing approaches are poised to revolutionize nearly all fields of biological research and medicine; however current approaches are low-throughput and limited in their sensitivity. The current technology is a novel method that could be implemented with existing reagents and equipment to improve de novo peptide sequencing...

Published: 5/17/2023 | Inventor(s): Eugene Tu, Fehmi Civitci, Kevin Schilling, Mingchong Dai, Nicholas Groves, Justin Plaut, Srivathsan Ranganathan, Andy Mendoza, Riccardo Carloni, Yu-Jui (Roger) Chiu, Emine (Sila) Ozdemir, Bruce Branchaud

Keywords(s): Research Tools, Research Tools - Other

Category(s): Proteomics, Research Tools

Label-free fluorescent sensing of protease activity

Summary The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. Technology Overview Dysregulated proteolytic activity is linked to many human diseases, including...

Published: 9/27/2023 | Inventor(s): Adem Yildirim, Bruce Branchaud, Justin Plaut, Srivathsan Ranganathan, Sean Speese, Corey Dambacher, Sarah Barnhill, Emma Olson

Keywords(s): Diagnostics, Imaging, Imaging - Other, Research Tools

Category(s): Imaging, Research Tools, Diagnostics