Search Results - summer+dowell+(gibbs)

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Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications
SummaryRhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...
Published: 10/27/2021   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Novel Fluorescent Dyes for In Vivo Nerve-Specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed novel, small molecule near infrared (NIR) nerve-specific fluorophores for diagnostic use in fluorescence-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visualization of nerves during surgical procedures,...
Published: 9/16/2020   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Fluorescence microscope for high resolution imaging and single-molecule tracking
SummaryDespite improvements in the field of fluorescence microscopy, a major drawback of existing microscopes is their spectral resolution, as they can distinguish only up to 3-4 colors at a time and requiring multiple excitation sources, limiting their practical use in biomedical research. Scientists at OHSU have recently solved this problem by developing...
Published: 1/30/2020   |   Inventor(s): Don Kania, Joe Gray, Steven Jacques, Summer Dowell (Gibbs), Xiaolin Nan
Keywords(s): Device, Engineering & Physical Science, Imaging, Research Tools
Category(s): Device, Engineering, Imaging, Physical Science, Research Tools
Novel Second Generation Fluorescent Dyes For In Vivo Nerve-specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed a second generation of novel, nerve-specific fluorescent dyes for diagnostic use in image-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visual identification of nerves. Technology OverviewDuring...
Published: 1/4/2019   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Adipose-specific fluorescent dyes for in vivo imaging
Technology SummaryResearchers at Oregon Health & Science University have developed novel adipose-specific fluorescent dyes for use in image-guided surgery of anatomical structures, such as nerves, that are surrounded by adipose tissue. The generated fluorophores exhibit reduced nerve accumulation, and demonstrate higher adipose-to-nerve and adipose-to-muscle...
Published: 1/4/2019   |   Inventor(s): Jesse Korber, Connor Barth, Summer Dowell (Gibbs)
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
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