Search Results - summer+dowell+(gibbs)

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Fluorophores for multicolor microscopy
SummaryMulticolor microscopy can be used to localize and visualize complex subcellular systems, but current systems are often limited in the number of fluorophores that can be imaged simultaneously. Oregon Health & Science University researchers have developed novel fluorophores that increase the number of channels and subcellular structures that...
Published: 12/2/2021   |   Inventor(s): Summer Dowell (Gibbs), Amy Bittel, Xiaolin Nan
Keywords(s): Imaging, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications
SummaryRhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...
Published: 7/1/2022   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
Novel Fluorescent Dyes for In Vivo Nerve-Specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed novel, small molecule near infrared (NIR) nerve-specific fluorophores for diagnostic use in fluorescence-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visualization of nerves during surgical procedures,...
Published: 1/27/2023   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Fluorescence microscope for high resolution imaging and single-molecule tracking
Summary Super-resolution microscopy and single-molecule tracking are powerful tools for biological research, but multicolor experiments have been difficult due to spectral crosstalk between fluorophores. Scientists at OHSU have developed a simple-to-use multispectral super-resolution microscope (MSSRM) system, compatible with live- or fixed-cell imaging...
Published: 9/30/2022   |   Inventor(s): Don Kania, Joe Gray, Steven Jacques, Summer Dowell (Gibbs), Xiaolin Nan
Keywords(s): Device, Engineering & Physical Science, Imaging, Research Tools
Category(s): Device, Engineering, Imaging, Physical Science, Research Tools
Novel Second Generation Fluorescent Dyes For In Vivo Nerve-specific Imaging
Technology SummaryResearchers at Oregon Health & Science University have developed a second generation of novel, nerve-specific fluorescent dyes for diagnostic use in image-guided surgery. The fluorophores can be administered directly to the surgical site or intravenously for the precise visual identification of nerves. Technology OverviewDuring...
Published: 6/17/2021   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Connor Barth
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
Adipose-specific fluorescent dyes for in vivo imaging
Summary Researchers at Oregon Health & Science University have developed novel adipose-specific fluorescent dyes for use in image-guided surgery of anatomical structures, such as nerves, that are surrounded by adipose tissue. The generated fluorophores exhibit reduced nerve accumulation, and demonstrate higher adipose-to-nerve and adipose-to-muscle...
Published: 10/3/2022   |   Inventor(s): Jesse Korber, Connor Barth, Summer Dowell (Gibbs)
Keywords(s): Diagnostics, Imaging
Category(s): Diagnostics, Imaging
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