Search Results - Diagnostics

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Machine-learning based forecasting of visual field deficits for glaucoma management
Summary The current technology is a machine learning algorithm that can accurately forecast glaucoma-induced visual field deficits and outperforms existing forecasting methods. This technology could allow for more efficient management of glaucoma by reducing the number of office-based visual field assessments. Technology Overview Glaucoma is characterized...
Published: 8/15/2024   |   Inventor(s): Ashkan Abbasi, Hiroshi Ishikawa, Sowjanya Gowrisankaran, Xubo Song, Bhavna Antony, Gadi (Chaim) Wollstein, Joel Schuman
Keywords(s): Diagnostics, Diagnostics - Other, Software, Software - Diagnostic/Detection
Category(s): Diagnostics, Software
Protease Activity Sensing Probes For Early Detection and Prognosis of Pancreatic Cancer
Summary The current technology is a liquid biopsy diagnostic screen for pancreatic ductal adenocarcinoma (PDAC), which is high throughput, requires very small blood volumes and has been validated in a large patient dataset. Technology Overview Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers and is typically discovered by accident...
Published: 7/31/2024   |   Inventor(s): Jared Fischer, Jose Luis Montoya Mira
Keywords(s): Diagnostics, Diagnostics - Cancer
Category(s): Diagnostics
5th Amendment to A Radio-Frequency-Free Hybrid Electrostatic/ Magnetostatic Cell for Transporting, Trapping, and Dissociating Ions in Mass Spectrometers - Internal Electron Source Configurations
Background The need to identify complex molecules in real-world samples has propelled mass spectrometry into a $3 billion industry growing 8% annually. The fragmentation of molecules within a mass spectrometer is necessary to accurately reveal their identity. The current approach uses a sledgehammer that complicates identification. Our technology...
Published: 6/17/2024   |   Inventor(s): Joseph Beckman, Valery Voinov, Douglas Barofsky
Keywords(s):  
Category(s): Diagnostics
CD74 as a biomarker and therapeutic target for familial platelet (FPD) disorder
Summary Research at OHSU has identified the CD74 signaling cascade as a potential therapeutic target and diagnostic biomarker for RUNX1-mutated familial platelet disorder (FPD), which is a premalignant condition for acute myeloid leukemia. Technology Overview Current estimates suggest as many as 18,000 people may be living with RUNX1-FPD in the United...
Published: 2/27/2024   |   Inventor(s): Anupriya Agarwal, Mona Mohammadhosseini
Keywords(s): Diagnostics, Diagnostics - Cancer, Diagnostics - Other, Therapeutics, Therapeutics - Cancer, Therapeutics - Other
Category(s): Diagnostics, Therapeutics
Electrocatalytic Polymer Biosensor
An extremely sensitive, stable, and specific biosensor using electrocatalytic molecularly imprinted polymers and no enzymes or reagents Background Electrochemical biosensors can successfully detect and quantify diverse biological samples including macromolecules, whole viruses, and cells. Due to their fabrication methods electrochemical biosensors...
Published: 8/25/2023   |   Inventor(s): Li-Jing Cheng, Sanjida Yeasmin
Keywords(s): Biosensors, Medical Device
Category(s): Medical Devices, Device, Diagnostics
Nanoparticle ultrasound contrast agents with high acoustic activity
Summary Contrast-enhanced ultrasound allows for low-cost minimally-invasive imaging; however, the size of typical contrast reagents prevents them from penetrating tumors thereby limiting their utility for cancer diagnostic and therapeutic purposes (theranostics). Oregon Health & Science University (OHSU) researchers have developed novel nanoparticle...
Published: 11/22/2023   |   Inventor(s): Adem Yildirim, Jose Luis Montoya Mira, Sadik Esener, Stuart Ibsen
Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Acoustic, Research Tools, Therapeutics
Category(s): Diagnostics, Imaging, Nanoscience & Microtechnologies, Research Tools, Therapeutics
Novel single-gene biomarker for acute myeloid leukemia prognosis
Summary The current technology is a novel set of biomarkers derived from the largest ever genomic and transcriptomic data set for acute myeloid leukemia (AML), which includes a novel single gene biomarker capable of strongly predicting AML prognosis. Technology Overview Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with an incidence...
Published: 9/27/2023   |   Inventor(s): Daniel Bottomly, Brian Druker, Kara Johnson, Stephen (Steve) Kurtz, Nicola Long, Shannon McWeeney, Anna Reister Schultz, Cristina Tognon, Jeffrey (Jeff) Tyner
Keywords(s): Diagnostics, Diagnostics - Cancer
Category(s): Diagnostics
Improved detection of heart-rate variability for wearable devices
Summary Heart-rate variability (HRV) is a suggested marker of the autonomic nervous system, but artifacts produced by movement with wrist worn devices decreases the validity and utility of this data. Oregon Health & Science University researchers have developed an improved method of removing motion artifacts, understanding the amount of data that...
Published: 3/24/2023   |   Inventor(s): David Sheridan, Steven Baker, Ryan Dehart
Keywords(s): Diagnostics, Research Tools, Software
Category(s): Diagnostics, Research Tools, Software
Anoxic/hypoxic brain imaging map
Summary Brain damage in newborns arises as a consequence of oxygen shortage in the brain. This injury is often difficult to diagnose in young children due to intrinsic differences between the developing and adult brain. Scientists at OHSU have developed a highly-accurate diagnostic analysis to localize brain injuries in developing as well as adult brains....
Published: 3/16/2023   |   Inventor(s): Jeffrey Pollock, Ningcheng (Peter) Li
Keywords(s): Diagnostics, Diagnostics - Neurology, Imaging, Imaging - MRI
Category(s): Diagnostics, Imaging
Effective combinations of targeted agents for hematologic malignancies
Summary Current treatment strategies for acute myeloid leukemia (AML) have low efficacy rates, due in part to the complex and heterogenous underlying genetics of this cancer. Oregon Health & Science University researchers have developed a precision medicine approach for the treatment of AML by identifying an effective combination therapy for a specific...
Published: 9/27/2023   |   Inventor(s): Jeffrey (Jeff) Tyner, Elie Traer, Stephen (Steve) Kurtz, Brian Druker, Andrew Kaempf, Christopher (Chris) Eide, Motomi (Tomi) Mori
Keywords(s): Diagnostics, Diagnostics - Cancer
Category(s): Diagnostics
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