Search Results - shannon+mcweeney

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Novel single-gene biomarker for acute myeloid leukemia prognosis
Summary The current technology is a novel set of biomarkers derived from the largest ever genomic and transcriptomic data set for acute myeloid leukemia (AML), which includes a novel single gene biomarker capable of strongly predicting AML prognosis. Technology Overview Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with an incidence...
Published: 9/27/2023   |   Inventor(s): Daniel Bottomly, Brian Druker, Kara Johnson, Stephen (Steve) Kurtz, Nicola Long, Shannon McWeeney, Anna Reister Schultz, Cristina Tognon, Jeffrey (Jeff) Tyner
Keywords(s): Diagnostics, Diagnostics - Cancer
Category(s): Diagnostics
Methods of treating venetoclax-resistant acute myeloid leukemia
SummaryAcute myeloid leukemia (AML) is difficult to treat due to the genetic heterogeneity of the disorder and accompanying drug resistance observed in many patients. Oregon Health & Science University researchers have identified a new therapeutic approach to overcome venetoclax resistance and improve outcomes and prognoses for AML patients experiencing...
Published: 9/19/2023   |   Inventor(s): Jeffrey (Jeff) Tyner, Haijiao Zhang, Beth Wilmot, Daniel Bottomly, Shannon McWeeney, Stephen (Steve) Kurtz, Christopher (Chris) Eide, Ravindra Majeti
Keywords(s): Diagnostics, Diagnostics - Cancer, Therapeutics, Therapeutics - Cancer
Category(s): Diagnostics, Therapeutics
Mutation-specific treatment strategies for acute myeloid leukemia
Summary The implementation of targeted therapies for acute myeloid leukemia (AML) has been challenged by complex mutational patterns within and across patients as well as a dearth of pharmacologic agents for most mutational events. Oregon Health & Science University (OHSU) researchers have identified treatment strategies for a broad scope of AML...
Published: 10/3/2022   |   Inventor(s): Jeffrey Tyner, Cristina Tognon, Brian Druker, Daniel Bottomly, Beth Wilmot, Stephen (Steve) Kurtz, Samantha Savage, Nicola Long, Anna Reister Schultz, Elie Traer, Shannon McWeeney
Keywords(s): Diagnostics, Diagnostics - Cancer, Therapeutics, Therapeutics - Cancer
Category(s): Therapeutics, Diagnostics
Subtyping autism using a novel machine learning method
Summary Autism spectrum disorder (ASD) is a heterogenous disease, making it difficult to develop diagnostic measures and effective treatments. Oregon Health and Science University researchers have developed a novel AI method for identifying ASD subgroups, which could help refine ASD diagnostic criteria and further the study of precision medicine for...
Published: 10/3/2022   |   Inventor(s): Eric Feczko, Damien Fair, Shannon McWeeney
Keywords(s): Diagnostics, Diagnostics - Neurology, Diagnostics - Other, Research Tools, Software - Diagnostic/Detection
Category(s): Diagnostics, Research Tools, Software
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