Search Results - gil+benedek

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Mouse/human chimera CD74: Design, codon optimization, cloning, expression in E coli, and purification
Protein: Recombinant human CD74This recombinant human version of CD74 is a 190 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed recombinant protein that includes the intracellular domain (N-terminal amino acid residues 1 to 30) and the transmembrane domain (amino acid residues 31 to 55) from the...
Published: 9/16/2020   |   Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek
Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools
Category(s): Biological Materials, Research Tools
Compounds that bind macrophage migration inhibitory factor
Technology Summary:Recombinant polypeptide composition for treatment of progressive multiple sclerosis (MS). This peptide approach selectively blocks key pro-inflammatory factors that could stop MS progression. Derived from CD74, the new composition competes for binding of the CD74 ligand, macrophage migration inhibitory factor (MIF). CD74 is a chaperone...
Published: 3/1/2016   |   Inventor(s): Arthur Vandenbark, Gil Benedek, Roberto Meza-Romero
Keywords(s): Therapeutics, Therapeutics - Immunology
Category(s): Therapeutics
Mouse CD74: Design, codon optimization, cloning, expression in E coli, and purification
Protein: Recombinant mouse CD74This recombinant mouse CD74 is a 191 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed mouse protein that includes the intracellular domain (N-terminal amino acid residues 1 to 30), the transmembrane domain (amino acid residues 31 to 55) and the extracellular domain...
Published: 3/1/2016   |   Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek
Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools
Category(s): Biological Materials, Research Tools
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