Search Results - biological+materials

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Rat monoclonal antibody to pS62-MYC
Summary MYC is a proto-oncogene associated with tumor pathogenesis in multiple cancer types, but currently there is a lack of reliable antibodies to assess MYC levels in FFPE patient samples. OHSU researchers have developed a rat monoclonal Serine 62 phosphorylated MYC antibody, which recognizes a form of MYC associated with increased protein stability...
Published: 4/13/2021   |   Inventor(s): Rosalie Sears, Colin Daniel
Keywords(s): Biological Materials, Biological Materials - Antibodies, Diagnostics - Cancer, Research Tools
Category(s): Biological Materials, Research Tools
A strong micro-promoter for AAV
Summary Viral mediated transgene delivery often utilizes specialized promoters that drive ubiquitous expression; however, these promoters are large and limit the amount of remaining space in AAV vectors for the transgene. The laboratory of Dr. Markus Grompe at OHSU has identified a novel promoter, which drives strong expression in multiple cell types...
Published: 10/9/2020   |   Inventor(s): Markus Grompe, Sunghee Chai
Keywords(s): Biological Materials, Therapeutics
Category(s): Biological Materials, Therapeutics
Mouse/human chimera CD74: Design, codon optimization, cloning, expression in E coli, and purification
Protein: Recombinant human CD74This recombinant human version of CD74 is a 190 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed recombinant protein that includes the intracellular domain (N-terminal amino acid residues 1 to 30) and the transmembrane domain (amino acid residues 31 to 55) from the...
Published: 9/16/2020   |   Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek
Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools
Category(s): Biological Materials, Research Tools
A biomimetic mineralizing cell-culture medium
A cell culture medium to control mineralization of extracellular matrix (hydrogels) in 2D and 3D cell cultures in regeneration studies. It allows the organic scaffold or matrix to mineralize over a set period of time in the presence of cells resulting in a structure that is similar to natural mineralized tissue.Executive Summary:Problem: Bones consist...
Published: 9/16/2020   |   Inventor(s): Luiz Bertassoni
Keywords(s): Biological Materials, Research Tools
Category(s): Biological Materials, Research Tools
Polyclonal rabbit antibody to gonadotropin-releasing hormone (GnRH)
A rabbit polyclonal antibody made against gonadotropin-releasing hormone (GnRH) that is highly specific to mammalian, fish and avian forms of GnRH and has been validated for use in immunohistochemistry and hormone assay systems. Relevant publication: Urbanski HF, Kim SO, Connolly ML (1990). The influence of photoperiod and 6-methoxybenzoxazolinone on...
Published: 9/16/2020   |   Inventor(s): Henryk Urbanski
Keywords(s): Biological Materials, Biological Materials - Antibodies
Category(s): Biological Materials
Human cytomegalovirus (HCMV) clinical isolate strain: Gerry
Technology Overview Dr. Jay Nelson has a collection of HCMV strains available for licensing as a package or on an individual strain basis. The full list of strains which are available are listed under OHSU Technology #1221. These are all clinical isolates that are at early passage and have not been adapted to any cell type and should therefore...
Published: 9/16/2020   |   Inventor(s): Jay Nelson
Keywords(s): Biological Materials, Biological Materials - Other, Research Tools, Research Tools - Reagents, Research Tools - Screening
Category(s): Biological Materials, Research Tools
Human cytomegalovirus (HCMV) clinical isolate strain: Edding
Technology Overview Dr. Jay Nelson has a collection of HCMV strains available for licensing as a package or on an individual strain basis. The full list of strains which are available are listed under OHSU Technology #1221. These are all clinical isolates that are at early passage and have not been adapted to any cell type and should therefore...
Published: 9/16/2020   |   Inventor(s): Jay Nelson
Keywords(s): Biological Materials, Biological Materials - Other, Research Tools, Research Tools - Reagents, Research Tools - Screening
Category(s): Biological Materials, Research Tools
Human cytomegalovirus (HCMV) clinical isolate strain: Dement
Technology Overview Dr. Jay Nelson has a collection of HCMV strains available for licensing as a package or on an individual strain basis. The full list of strains which are available are listed under OHSU Technology #1221. These are all clinical isolates that are at early passage and have not been adapted to any cell type and should therefore...
Published: 9/16/2020   |   Inventor(s): Jay Nelson
Keywords(s): Biological Materials, Biological Materials - Other, Research Tools, Research Tools - Reagents, Research Tools - Screening
Category(s): Biological Materials, Research Tools
Human cytomegalovirus (HCMV) clinical isolate strain: Davis
Technology Overview Dr. Jay Nelson has a collection of HCMV strains available for licensing as a package or on an individual strain basis. The full list of strains which are available are listed under OHSU Technology #1221. These are all clinical isolates that are at early passage and have not been adapted to any cell type and should therefore...
Published: 9/16/2020   |   Inventor(s): Jay Nelson
Keywords(s): Biological Materials, Biological Materials - Other, Research Tools, Research Tools - Reagents, Research Tools - Screening
Category(s): Biological Materials, Research Tools
Human cytomegalovirus (HCMV) clinical isolate strain: Brown
Technology Overview Dr. Jay Nelson has a collection of HCMV strains available for licensing as a package or on an individual strain basis. The full list of strains which are available are listed under OHSU Technology #1221. These are all clinical isolates that are at early passage and have not been adapted to any cell type and should therefore...
Published: 9/16/2020   |   Inventor(s): Jay Nelson
Keywords(s): Biological Materials, Biological Materials - Other, Research Tools, Research Tools - Reagents, Research Tools - Screening
Category(s): Biological Materials, Research Tools
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