Search Results - arthur vandenbark

5 Results Sort By:
DRĪ±1-MOG-35-55 treatment of Traumatic Brain Injury
Treatment of traumatic brain injury is limited to medications to limit secondary damage to the brain, surgery to relieve pressure on the brain, and rehabilitation. The OHSU discovery uses a proprietary construct comprised of the human leukocyte antigen (HLA)-DRα1 domain linked covalently to mouse (m)MOG-35-55 peptide (DRα1-MOG-35-55 con...
Published: 3/20/2017   |   Inventor(s): Halina Offner-Vandenbark, Arthur Vandenbark
Keywords(s): Therapeutics, Therapeutics - Neurology
Category(s): Therapeutics
Compounds that bind macrophage migration inhibitory factor
Compositions for recombinant polypeptides derived from CD74, a chaperone that assists with the folding and trafficking of Class II MHC (Major Histocompatibility Complex), that compete for binding of the CD74 ligand macrophage migration inhibitory factor (MIF). Possible use as a therapeutic to block inflammation driven by MIF interactions with CD 74...
Published: 3/1/2016   |   Inventor(s): Arthur Vandenbark, Gil Benedek, Roberto Meza-Romero
Keywords(s): Therapeutics, Therapeutics - Immunology
Category(s): Therapeutics
Mouse CD74: Design, codon optimization, cloning, expression in E coli, and purification
Protein: Recombinant mouse CD74This recombinant mouse CD74 is a 191 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed mouse protein that includes the intracellular domain (N-terminal amino acid residues 1 to 30), the transmembrane domain (amino acid residues 31 to 55) and the extracellular dom...
Published: 3/1/2016   |   Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek
Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools
Category(s): Biological Materials, Research Tools
Mouse/human chimera CD74: Design, codon optimization, cloning, expression in E coli, and purification
Protein: Recombinant human CD74This recombinant human version of CD74 is a 190 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed recombinant protein that includes the intracellular domain (N-terminal amino acid residues 1 to 30) and the transmembrane domain (amino acid residues 31 to 55) from ...
Published: 3/1/2016   |   Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek
Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools
Category(s): Biological Materials, Research Tools
Methods of selecting T cell receptor V peptides for therapeutic use
Technology OverviewTechnology 0618 represents a method to identify a T cell receptor (TCR) peptide for use as a therapeutic agent in patients with autoimmune diseases. Regulatory T cells are generated that can inhibit the activation of inflammatory cells involved in autoimmune diseases to be used as a treatment for subjects. Methods are also ...
Published: 2/10/2010   |   Inventor(s): Arthur Vandenbark
Keywords(s): Research Tools - Screening
Category(s): Research Tools
© 2019. All Rights Reserved. Powered by Inteum