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Development of a Novel Zebrafish Screening System and Identification of a Novel Protein That Induces Pancreatic Beta-Cell Proliferation

This invention enables a novel, microbiome-derived approach to diabetes treatment by leveraging a protein from the gut bacterium Aeromonas that increases pancreatic β cell number through enhanced proliferation, differentiation, and survival. By targeting restoration of insulin-producing β cells, the technology addresses a core unmet need in...

Published: 1/6/2026 | Inventor(s): Karen Guillemin, Jennifer Hampton

Keywords(s): Biochemistry, Biological Materials, Biotech, Therapeutics, Zebrafish

Category(s): Diagnostics, Therapeutics, Research Tools