Search Results - karen+guillemin

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SpdE, a Novel Amino Acid-sensing Diguanylate Cyclase

1. Technology Overview The invention introduces SpdE, a novel bacterial protein that senses specific amino acids (valine, proline, and isoleucine) at nanomolar concentrations. This highly sensitive protein offers significant potential for applications in clinical diagnostics, biotechnology, and industrial processes. The technology leverages established...

Published: 1/8/2026 | Inventor(s): Karen Guillemin, Emily Sweeney, Catherine Robinson

Keywords(s): Science

Category(s): Diagnostics, Research Tools, Therapeutics

Development of a Novel Zebrafish Screening System and Identification of a Novel Protein That Induces Pancreatic Beta-Cell Proliferation

This invention enables a novel, microbiome-derived approach to diabetes treatment by leveraging a protein from the gut bacterium Aeromonas that increases pancreatic β cell number through enhanced proliferation, differentiation, and survival. By targeting restoration of insulin-producing β cells, the technology addresses a core unmet need in...

Published: 1/6/2026 | Inventor(s): Karen Guillemin, Jennifer Hampton

Keywords(s): Biochemistry, Biological Materials, Biotech, Therapeutics, Zebrafish

Category(s): Diagnostics, Therapeutics, Research Tools