Search Results - pharmaceuticals

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Chlamydia Trachomatis Genomic DNA Fragments Encoding Novel Vaccine Candidates For Prevention Of Chlamydial Diesase

The invention relates to the detection of Chlamydia and to the diagnosis, treatment and prevention of Chlamydia infections in animals. The invention includes the use of Chlamydia proteins that show enhanced expression in the reticulate body (RB) stage relative to the elementary body (EB) stage of the Chlamydia life cycle. These proteins are not...

Published: February 11, 2010 | Inventor(s): John Bannantine, Daniel Rockey

Keywords(s): Biomedical, Biotechnology, Pharmaceuticals, Veterinary Science & Technologies

Category(s): Vaccines

A Coated, Platform-Generating Tablet

This invention teaches a method where controlled release tablet formulation which is relatively easy and inexpensive to produce using standard equipment, and which can easily be modified by the formulator to program drug release as desired. This invention describes tablets containing expending hydrophilic polymer gums in a matrix tablet which h...

Published: July 01, 2009 | Inventor(s): James Ayres

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, Pharmaceuticals

Category(s): Therapeutics

Biosynthetic Gene Cluster of the anticancer antibiotic pactamycin and its potential use

About 70 percent of the bacteria that cause infections in hospitals are now resistant to at least one of the drugs most commonly used for treatment. For example, some organisms are resistant to all approved antibiotics and can only be treated with experimental and potentially toxic drugs. Therefore, to stay ahead of the development of antibact...

Published: June 30, 2009 | Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt

Keywords(s): Biotechnology, Pharmaceuticals

Category(s): Therapeutics

Biopolymer Thickener

Lactic acid bacteria are capable of producing many types of exopolysaccharides, some of which play important roles as thickeners and stabilizers in food products. This invention includes a natural isolate of Lactococcus lactis ssp. cremoris that produces a smooth body and excellent texture in low fat or no fat dairy products. This bacterial str...

Published: June 30, 2009 | Inventor(s): Janine Trempy, Eric Knoshaug, William Sandine, Karen Dierksen, Jeff Ahlgren

Keywords(s): Food Science / Nutrition, Medical Science & Technologies, Pharmaceuticals

Category(s): Therapeutics

Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin

This technology describes the molecular cloning of the enduracidin biosynthetic gene cluster from Streptomyces fungicidicus, the characterization of the individual genes in the gene cluster and the proteins encoded thereby. In addition, enduracidin analogs are described which are produced by mutant Streptomyces organisms. For example, tetrah...

Published: June 18, 2009 | Inventor(s): T. Mark Zabriskie, Xihou Yin

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, Pharmaceuticals

Category(s): Therapeutics

Hydrazide-Functionalized Isotope-Coded Affinity Tag (HICAT)

Current techniques for detecting lipid- generated aldehydes have the important disadvantage that they are not quantitative. This invention however provides a new analytical method that is capable of identifying, characterizing, and quantifying oxylipids-conjugated proteins in complex peptide mixtures. The invention provides a new group of reag...

Published: June 18, 2009 | Inventor(s): Claudia Susanne Maier, Jan Frederik Stevens

Keywords(s): Biomedical, Biotechnology, Pharmaceuticals

Category(s): Research Tools

Induction of apoptosis in cancer cells

The present invention provides compounds that are useful inducers or inhibitors of apoptosis or apoptosis preceded by cell-cycle arrest. This invention provides pharmaceutical compositions and methods for treating mammals with leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells. U.S. Patent: 7,0...

Published: June 18, 2009 | Inventor(s): Mark Leid, Marcia Dawson, Joseph Fontanta, Xiao-kun Zhang, Ling Jong, Peter Hobbs

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, Pharmaceuticals

Category(s): Veterinary Science, Therapeutics

Novel Enteric Coated Compositionsthat Release Therapeutics in Gastric Fluid

The invention is directed to a pharmaceutical composition for site specific delivery of drugs to the stomach or to small intestine. This pharmaceutical composition consists of enteric material composition that delivers drug into gastric fluid and into intestinal fluid. The specific enteric material composition allows gastric fluid to penetrate...

Published: June 18, 2009 | Inventor(s): James Ayres

Keywords(s): Biomedical, Biotechnology, Pharmaceuticals

Category(s): Therapeutics

Isolation and Structure Elucidation of the Antiproliferative Peptide Coibamide A

This technology is related to cancer treatment. Chemotherapy has become a focus in cancer treatment, however natural products are the ultimate source of more than fifty percent of the clinical trials for the treatment of caner. The present invention relates to isolation, structure, and purification, of the novel antiproliferative cyclic peptid...

Published: June 16, 2009 | Inventor(s): Kerry McPhail, Rebecca Medina, William Gerwick, Douglas Geoger, Susan Moobery, Todd Capson

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, Pharmaceuticals

Category(s): Therapeutics

Methods of Producing Validienamycin Analogs and Uses

The antifungal agent validamycin A is a commercially important compound due to its wide application in controlling fungal infection of rice plants caused by Rhizoctonia solani. This invention is a method of producing validamycin A analogs and biosynthesis and their potential use. The invention further relates to the use of validamycin biosynth...

Published: June 16, 2009 | Inventor(s): Taifo Mahmud, Hui Xu, Jongtae Yang, Zixin Deng, Linquan Bai

Keywords(s): Pharmaceuticals, Medical Science & Technologies, Biomedical

Category(s): Therapeutics

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