Search Results - nanomedicine

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Next-Generation ROS Nanotherapy for Targeted Cancer Destruction

Produces complementary reactive oxygen species in tumors, enabling efficient tumor killing without external activation Background Conventional cancer treatments such as surgery, chemotherapy, and radiotherapy are often invasive, non-specific, and associated with systemic toxicity and long-term side effects. Emerging nanomedicine approaches improve...

Published: 5/8/2026 | Updated: 5/8/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Chao Wang

Keywords(s): breast cancer, chemodynamic therapy (CDT), Fenton reaction, ferrous, immuno-oncology, metal-organic framework (MOF), nanomedicine, oncology therapeutics, porphyrin, reactive oxygen species (ROS), Russell mechanism, solid tumor, tumor microenvironment, tumor suppression, tumor targeting, tumour microenvironment

Category(s): Therapeutics

Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia

Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Yoon Tae Goo

Keywords(s): anti-inflammatory, Anti-inflammatory drugs, biodegradable, biodistribution, blood-brain barrier, brain delivery, brain inflammation, CNS drug delivery, cytokine expression, Drug Delivery, Drug Development, glutathione, immune cell, immunohistochemistry, irak4 inhibitor, lipopolysaccharides, microglia, mouse model, nanocarrier, nanocarriers, nanomedicine, neuroinflammation, pancreatic cancer, pharmaceuticals, pharmacokinetics, preservation, pro-inflammatory cytokine, small molecules, water-soluble, weight maintenance

Category(s): Therapeutics