Search Results - biotechnology

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Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin
Technology Description To produce a library of S. fungicidicus mutants, an in vitro transposon-based method was devised to randomly insert a selectable marker and oriT element in fosmid inserts carrying segments of the enramycin biosynthetic gene cluster and adjacent regions. This library of mutagenized fosmids was screened to identify specific disrupted...
Published: 3/13/2024   |   Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银
Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics
Shoot Inducing Genes for Improved Production of Transgenic Plants
This invention, using Agrobacterium gene clusters, enables passive regeneration of transgenic cells without the need for plant hormones Background For plants which are recalcitrant (difficult) to transform, poor performance is usually associated with inadequate DNA delivery or difficult regeneration response. There is a need for improved methods...
Published: 8/25/2023   |   Inventor(s): Greg Goralogia, Steven Strauss
Keywords(s): Agrobacterium, Biotechnology, gene transfer, gene-edited, transgenic
Category(s): Agricultural
Mouse Model for Vitamin D Regulated Antimicrobial Peptide Expression
Technology Description Oregon State University is seeking collaborative research opportunities or licensees for a humanized mouse model for vitamin D regulated antimicrobial peptide expression. The developed animal model is a transgenic mouse that carries a 6.2 kb human genomic DNA that possess the cathelicidin antimicrobial peptide (CAMP) gene. Vitamin...
Published: 1/16/2023   |   Inventor(s): Adrian Gombart
Keywords(s): Animal Model, Antimicrobial, Biotechnology, Vitamin D regulation
Category(s): Therapeutics, Biological Materials, Research Tools
Mouse Model for Insulin Resistance
Opportunity Description Oregon State University is SEEKING RESEARCH COLLABORATIONS or LICENSEES for pharmaceutical R&D, or obesity and diabetes research, to exploit A NEW TYPE 2 DIABETES MOUSE MODEL. Created by Oregon State University professor Chrissa Kioussi, the mouse model is a SKELETAL MUSCLE SPECIFIC PITX2 NULL MOUSE. Development of the mouse...
Published: 5/10/2021   |   Inventor(s): Chrissa Kioussi
Keywords(s): Biotechnology, Diabetes, insulin resistance, pharmaceuticals, Type 2 Diabetes
Category(s): Biological Materials, Chemical, Medical Devices, Therapeutics
Fluidic devices with photo-actuated gates and re-patternable channels
Technology Description This patented technology (US 8,580,161) describes ways of controlling fluid movement in microfluidic devices and microwell plates. Fluid movement is achieved by controlling gating, valving, and permeation using light-actuated compounds such as a spiropyran. Prototypes have been tested in the lab and we are looking for a licensee...
Published: 5/10/2021   |   Inventor(s): Vincent Remcho, Jintana Nammoonnoy, Myra Koesdjojo
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Biological & Environmental Engineering, Biomedical, Biotechnology, Chemicals / Chemical Engineering, Diagnostic, Medical Science & Technologies, Multiplexing, Nanotechnology, Physics / Applied Engineering, Research Tools
Category(s): Device, Chemical, Chemistry, Diagnostics, Engineering, Nanoscience & Microtechnologies, Research Tools
Antiproliferative Peptide Coibamide A
Technology Description Researchers at Oregon State University have discovered, isolated, and purified a new antiproliferative compound, Coibamide A, which provides for a new and potent family of antiproliferative compounds. The peptidic molecular structure of Coibamide A presents a large number of possible combinations and permutations of component...
Published: 5/10/2021   |   Inventor(s): Kerry Mcphail, Rebecca Medina, William Gerwick, Douglas Goeger, Susan Moobery, Todd Capson
Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics
Genetic incorporation of tetrazine amino acids and use in bioorthogonal ligations
Technology Description Ideal bioorthogonal reactions containing high reaction rates, high selectivity and high stability would allow for stoichiometric labeling of biomolecules in minutes and eliminate the need to washout excess labeling reagent. Currently no general method exists for controlled stoichiometric or sub-stoichiometric labeling of proteins...
Published: 3/19/2024   |   Inventor(s): Ryan Mehl, Robert Blizzard
Keywords(s): Biological & Environmental Engineering, Biomedical, Biotechnology, Diagnostic, Labels, Protein Polymer Hybrids, Research Tools
Category(s): Diagnostics
Method of Using and Producing Tropoelastin and Tropoelastic Biomaterials
PSU researchers, in collaboration with the Oregon Biomedical Engineering Institute, have developed a new biomaterial that can be used to coat biomedical implants. The technology is currently licensed and under development.
Published: 8/6/2015   |   Inventor(s): Carl Wamser
Keywords(s): Biotechnology
Category(s): Chemistry
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