Search Results - siva+kolluri

3 Results

Sort By:

New Drugs for Treatment of Type 1 Diabetes

Technology Description Oregon State University is seeking a licensee to develop and commercialize a new family of compounds that target the Ah receptor for treatment of Type 1 Diabetes. The compounds are based on the parental compound 11-Cl-BBQ, the use of which is described PCT patent application No. US2015/057873, in U.S. patent No. 10,308,649, and...

Published: 8/3/2023 | Inventor(s): Siva Kolluri, Nancy Kerkvliet, Jit Chakravarty, Sebastian Bernales

Keywords(s): Diabetes, pharmaceuticals, Therapeutic, Type 1 Diabetes

Category(s): Therapeutics

Anti-cancer Compounds

Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effective...

Published: 1/7/2022 | Inventor(s): Siva Kolluri, Prasad Kopparapu

Keywords(s): Cancer, metastatic tumor, small peptides

Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics

New Approach for Treatment of Type I Diabetes

Technology Description This licensing and collaborative research opportunity relates to a new approach to treating diabetes mellitus type 1 (T1DM). The patent pending methods of treatment focus on the use of compounds that provide suppression of autoimmune responses that lead to destruction of pancreatic beta cells. The possibility of preventing disease...

Published: 5/24/2023 | Inventor(s): Nancy Kerkvliet, Siva Kolluri

Keywords(s): Diabetes, Drug, Immune, Therapeutic

Category(s): Chemical, Therapeutics