Search Results - medical+science+%26+technologies

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Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin

Technology Description To produce a library of S. fungicidicus mutants, an in vitro transposon-based method was devised to randomly insert a selectable marker and oriT element in fosmid inserts carrying segments of the enramycin biosynthetic gene cluster and adjacent regions. This library of mutagenized fosmids was screened to identify specific disrupted...

Published: 3/13/2024 | Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Photoreactor for Treatment of Jaundice

Technology Description Oregon State University is seeking a licensee or research collaborator for development or commercialization of a microfluidic visible light photoreactor for the treatment of jaundice in neonatal patients. The device enables safe extracorporeal blood treatment, making it an excellent replacement for equally effective, yet risky,...

Published: 1/16/2023 | Inventor(s): John Lahmann, Adam Higgins

Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Bilirubin, Blood, hyperbilirubinemia, light, Medical Science & Technologies, Neonatal, Newborn, Photoreactor, Sepsis, treatment

Category(s): Medical Devices, Therapeutics, Engineering

A Method to Treat Alzheimer’s, Heart and Liver Diseases

Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a lipophilic...

Published: 5/26/2021 | Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby

Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease

Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics

Engineering Mechanisms to Connect One Muscle to Multiple Tendons in Surgery

Technology Description This technology is a new tendon-transfer surgical procedure that uses an implanted passive engineering mechanism for attaching multiple tendons to a single donor muscle. This improves hand function in physical interaction tasks such as grasping over the conventional method of directly suturing multiple tendons to a single muscle.Features...

Published: 1/7/2022 | Inventor(s): Ravi Balasubramanian, Taymaz Homayouni

Keywords(s): Biomedical, Materials Science, Medical Science & Technologies, Veterinary Science & Technologies

Category(s): Medical Devices, Engineering, Device, Therapeutics

Fluidic devices with photo-actuated gates and re-patternable channels

Technology Description This patented technology (US 8,580,161) describes ways of controlling fluid movement in microfluidic devices and microwell plates. Fluid movement is achieved by controlling gating, valving, and permeation using light-actuated compounds such as a spiropyran. Prototypes have been tested in the lab and we are looking for a licensee...

Published: 5/10/2021 | Inventor(s): Vincent Remcho, Jintana Nammoonnoy, Myra Koesdjojo

Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Biological & Environmental Engineering, Biomedical, Biotechnology, Chemicals / Chemical Engineering, Diagnostic, Medical Science & Technologies, Multiplexing, Nanotechnology, Physics / Applied Engineering, Research Tools

Category(s): Device, Chemical, Chemistry, Diagnostics, Engineering, Nanoscience & Microtechnologies, Research Tools

Antiproliferative Peptide Coibamide A

Technology Description Researchers at Oregon State University have discovered, isolated, and purified a new antiproliferative compound, Coibamide A, which provides for a new and potent family of antiproliferative compounds. The peptidic molecular structure of Coibamide A presents a large number of possible combinations and permutations of component...

Published: 5/10/2021 | Inventor(s): Kerry Mcphail, Rebecca Medina, William Gerwick, Douglas Goeger, Susan Moobery, Todd Capson

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Natural dairy product biopolymer thickener from Lactococcus lactis Ropy352

Technology Description Natural polysaccharides produced by Ropy352 gives the yogurt a thick, smooth and sweet taste and are generally considered safe. Therefore, no other polysaccharides, like dextran, xanthan, and gellan from potentially pyrogenic inducing bacteria, are needed.Features & Benefits Natural and Generally Regarded As Safe (GRAS)Yogurt...

Published: 3/17/2024 | Inventor(s): Janine Trempy, Eric Knoshaug, William Sandine, Jeff Ahlgren, Karen Dierksen

Keywords(s): Agriculture, Food Science / Nutrition, Medical Science & Technologies, pharmaceuticals

Category(s): Agricultural, Chemistry, Research Tools