Search Results - cancer

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Anticancer Compounds
Technology Description Oregon State University seeks a licensee or collaborative research and development partner to further develop and commercialize a family of newly identified anti-cancer compounds. All inquiries are welcome. Preclinical studies have demonstrated that these compounds are effective in inhibiting viability of Ewing's sarcoma cell...
Published: 5/2/2018   |   Inventor(s): Mark Leid, Elahe Esfandiari
Keywords(s): Cancer, Sarcoma, Tumor
Category(s): Therapeutics
Anti-cancer Compounds
Technology Description This technology describes using compounds to induce cell death in Bcl-2 high-expressing cancer cells refractory to chemotherapeutic drugs but with minimal effects on normal cells. Further, the anti-cancer effect of these compounds is also confirmed in mouse xenograft studies. These results indicate that our compounds are effe...
Published: 4/10/2017   |   Inventor(s): Siva Kolluri, Prasad Kopparapu
Keywords(s): Cancer, metastatic tumor, small peptides
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
A Method to Treat Alzheimer’s, Heart and Liver Diseases
Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a ...
Published: 3/28/2017   |   Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby
Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease
Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics
Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity
Technology Description: Patented (US8957251) pactamycin analogs having antibacterial, antitumor, antiviral and antimalarial activity. Also patented are biosynthetic methods of producing both the identified and additional new analogs. The identified analogs and methods of biosynthetic production provide a promising opportunity for discovery and deve...
Published: 5/17/2016   |   Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt
Keywords(s): Antibiotics, Antiviral, Cancer, Malaria
Category(s): Therapeutics
Lymphatic drug delivery system and drugs for metastatic melanoma
Technology Description Oregon State University is seeking a licensee for a patented drug delivery system for the treatment of metastatic melanoma. The system is composed of biodegradable, biocompatible, and stable nanoparticles built from amphiphilic block copolymers and contains a mix of drugs commonly used to treat cancer, all while being nontoxi...
Published: 11/23/2015   |   Inventor(s): Adam Alani
Keywords(s): Cancer, Drug, Drug Delivery, drugs, lymphatic, melanoma, metastatic tumor, Pharmaceuticals, Therapeutic
Category(s): Therapeutics
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