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High Sensitivity and Specificity Biosensor
This sensor architecture enables signal amplification for detection of biomarkers and analytes at extremely low concentration Background Molecular diagnostics increasingly rely on sensitive detection of biomarkers such as nucleic acids, proteins, and cytokines in complex biological samples. Traditional biosensor probes often suffer from signal...
Published: 5/9/2026
|
Updated: 5/9/2026
|
Inventor(s):
Li-Jing Cheng
,
Ye Liu
Keywords(s):
analyte
,
assay
,
biomarkers
,
biosensor
,
diagnostic
,
immuno
assay
,
magnetic nanoparticles
,
molecular diagnostics
,
molecular probe
,
multiplexed detection
,
nanoparticle
,
nanoparticles
,
plasmonics
,
raman system
,
sensor
,
signal amplification
Category(s):
Diagnostics
Inclusion Body–Based Expression Platform for PTM-Preserved Proteins (PIInBody)
Enables high-yield production of unstable, post-translationally modified proteins by protecting them during expression and gentle release Background Intrinsically disordered proteins (IDPs), particularly those carrying labile post-translational modifications (PTMs), are difficult to produce recombinantly due to degradation, aggregation, and loss...
Published: 5/9/2026
|
Updated: 2/19/2026
|
Inventor(s):
Richard Cooley
,
Cat Vesely
,
Ryan Mehl
Keywords(s):
antibody
,
architecture
,
assay
,
assay
development
,
bacterial
,
bacterial expression system
,
binders
,
cancer
,
code
,
denaturing
,
diagnostic
,
drug development
,
enzymatic
,
epitope
,
expression platform
,
expression system
,
fusion
,
homogeneous
,
inclusion
,
isotopic
,
isotopic labeling
,
mass spectrometry
,
neurodegeneration
,
post-translational
,
protein
,
purification
,
reagent
,
recombinant
,
screening
assay
s
,
structural biology
Category(s):
Biological Materials
Paper-based Microfluidic Well Plates
Technology Description Oregon State University is seeking a licensee for a paper-based microfluidic well plate systems that are cheaper, modifiable replacements for plastic well plate systems currently in use. This technology has been tested in a 96-well plate embodiment for analysis of a panel of disease biomarkers, environmental and health toxins,...
Published: 5/26/2021
|
Updated: 12/15/2017
|
Inventor(s):
Christopher Heist
,
Sumate Pengpumkiat
,
Gayan Bandara
,
Vincent Remcho
Keywords(s):
Assay
,
Chemicals / Chemical Engineering
,
Detection
,
Diagnostic
,
Microfluidics
,
Paper
Category(s):
Research Tools
,
Diagnostics
,
Chemical
,
Nanoscience & Microtechnologies
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