Search Results - antimicrobial

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Mouse Model for Vitamin D Regulated Antimicrobial Peptide Expression

Technology Description Oregon State University is seeking collaborative research opportunities or licensees for a humanized mouse model for vitamin D regulated antimicrobial peptide expression. The developed animal model is a transgenic mouse that carries a 6.2 kb human genomic DNA that possess the cathelicidin antimicrobial peptide (CAMP) gene. Vitamin...

Published: 1/16/2023 | Inventor(s): Adrian Gombart

Keywords(s): Animal Model, Antimicrobial, Biotechnology, Vitamin D regulation

Category(s): Therapeutics, Biological Materials, Research Tools

Peptide Inhibitors of Gonorrhoeae

Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...

Published: 12/23/2021 | Inventor(s): Aleksandra Sikora, Konstantin Korotkov

Keywords(s): Antibiotics, Antimicrobial, Drug, Drug Development, Gonorrhea, Inhibitor, Microbiology, Peptide, Therapeutic

Category(s): Therapeutics, Vaccines

Antimicrobial Surface Coating

Technology Description Some known antimicrobial compounds, such as nisin or other lantibiotics, which have highly surface active and bactericidal action, can be linked with a block polymer to form a long lasting antimicrobial surface coating. As for the block polymer, PLURONIC and end group activated polymers (EGAP) are used. Both of them can contact...

Published: 12/23/2021 | Inventor(s): Joseph Mcguire, Pranav Joshi

Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Antimicrobial, Peptide, polymer

Category(s): Engineering