Search Results - t.+mark+zabriskie

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Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin
Technology Description To produce a library of S. fungicidicus mutants, an in vitro transposon-based method was devised to randomly insert a selectable marker and oriT element in fosmid inserts carrying segments of the enramycin biosynthetic gene cluster and adjacent regions. This library of mutagenized fosmids was screened to identify specific disrupted...
Published: 3/13/2024   |   Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银
Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals
Category(s): Therapeutics
Apoptolidin-producing Strain Amycolatopsis sp. ICBB 8242
A bacterial strain that produces a family of antibiotic compounds known as the apoptolidins. The predominant compound produced is apoptolidin A.*Applications include antibiotic and anticancer lead compound development.*Benefits include increased yield compared to published strains.Seeking a… LICENSEE INDUSTRY RESEARCH...
Published: 3/17/2024   |   Inventor(s): T. Zabriskie, Dwi Andreas Santosa, Taifo Mahmud, Philip Proteau
Keywords(s): Chemicals / Chemical Engineering, pharmaceuticals
Category(s): Research Tools
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