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Diagnostic Method for Predicting Increased Risk of Coronary Artery Disease
Technology Description Oregon State University is seeking a licensee to develop and commercialize products based on a method for detecting a subject's oxylipin level to predict or determine the subject’s risk for or stage of coronary artery disease (CAD). This method is dependent on the inventors' discovery that the presence and number...
Published: 5/10/2021
|
Inventor(s):
Manuel Garcia-Jaramillo Rodriguez
,
Gerd Bobe
,
Claudia Maier
,
Donald Jump
,
Armando Alcázar-Magaña
,
Dai-Trang (Elizabeth) Le
,
Sanjiv Kaul
,
Nabil Alkayed
Keywords(s):
artery
,
CAD
,
coronary
,
Diagnostic
,
heart disease
Category(s):
Diagnostics
Split-luciferase complementation to measure soluble epoxide hydrolase dimerization
Technology Overview Soluble epoxide hydrolase (sEH) inhibition is a therapeutic target for a large number of cardiovascular diseases. Disrupting dimerization of sEH reduces hydrolase activity and shifts the sub-cellular localization of sEH to peroxisomes. The current technology is a split-firefly luciferase assay that not only measures disruption of...
Published: 9/19/2023
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Inventor(s):
Jonathan Nelson
,
Nabil Alkayed
,
Xiangshu Xiao
Keywords(s):
Biological Materials
,
Research Tools - Screening
Category(s):
Biological Materials
,
Research Tools
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