Search Results - diagnostics+-+platforms

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New method of targeted sequencing using CRISPR-Cas12a-mediated capture of nucleic acids
SummaryOregon Health & Science University researchers have developed an improved method of targeted sequencing that is inexpensive, scalable and could be utilized to create custom sequencing panels for genetic testing.Technology OverviewNumerous methods for targeted sequencing have been developed but each have their own limitations. PCR-based approaches...
Published: 7/22/2021   |   Inventor(s): Brian O'Roak, Andrew Adey, Taylor Mighell, Ryan Mulqueen, Casey Thornton
Keywords(s): Diagnostics - Platforms, Next Generation Sequencing, Research Tools
Category(s): Research Tools
Method for identifying Family-Member Specific Targets of Mono-PARPs
Summary Technology developed at OHSU provides a novel method to identify proteins regulated by PARP mono-ADP-ribosylation (MARylation), a post-translational modification carried out by the majority of enzymes within this family. This tool has the ability to link such PARPs to specific targets and broader biological pathways, thereby increasing our understanding...
Published: 8/29/2016   |   Inventor(s): Michael Cohen, Ian Carter-O'Connell, Rory Morgan, Haihong Jin
Keywords(s): Diagnostics - Platforms, Research Tools
Category(s): Diagnostics, Proteomics, Research Tools
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