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Fluorophore-Tagged Cisplatin
Many types of cancer, including carcinomas, lymphomas, sarcomas, and others, are treated with the chemotherapy agent Cisplatin. Based on the element platinum, cisplatin causes apoptosis in cancer cells by cross-linking their DNA. Like many chemotherapy agents, Cisplatin's effectiveness could be improved by better understanding how the body moves it...
Published: 7/20/2009   |   Inventor(s): Robert Strongin, Martha Sibrian-Vazquez, Jorge Escobedo, Peter Streyger
Keywords(s): Biology, Chemistry, Drug Screening, Therapeutics
Category(s): Therapeutics
Screen for Redox Activity of Compounds
The design of new and effective drugs is a multi-billion dollar business, requiring great expense and extensive testing of drug candidate compounds. Obtaining a better understanding of the pharmacodynamics and mechanisms of action of drug candidates is an important and necessary step in optimizing any lead compound. A property of increasing...
Published: 6/3/2009   |   Inventor(s): Jonathan Abramson, Benjamin Marinov, Rotimi Olojo
Keywords(s): Biology, Chemistry, Drug Screening
Category(s): Therapeutics
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