Search Results - bingbing li

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In vitro expansion of liver repopulating cells
Researchers at Oregon Health & Science University have developed a novel tissue culture media capable of expanding primary epithelial cells from cirrhotic human livers for greater than 10 passages, while retaining the ability to re-differentiate into hepatocytes capable of liver repopulation.
Published: 3/7/2017   |   Inventor(s): Markus Grompe, Bin Li, Yuhan Wang
Keywords(s): Research Tools - Reagents
Category(s): Research Tools
Novel Pyrroloquinazolines as Anti-cancer Agents
Novel and Effective Compounds for Triple Negative Breast Cancer Researchers at Oregon Health & Science University have discovered a novel lead compound that is active against triple negative breast cancer through what is believed to be a novel (unknown at this point-target identification underway) mechanism of action. The lead compound is not...
Published: 10/16/2013   |   Inventor(s): Xiangshu Xiao, Jingjin Chen, Bingbing Li
Keywords(s): Therapeutics - Cancer
Category(s): Therapeutics, Chemical
Naphthamides as anticancer agents inhibiting CREB-mediated gene transcription
Value Proposition: Researchers at Oregon Health & Science University discovered a novel compound that regulates transcription activity of CREB via a novel mechanism of action. Lead optimization resulted in a first in class chemical series that is potent and highly selective. The efficacy of these compounds has been validated in vitro (e.g.,...
Published: 5/1/2013   |   Inventor(s): Xiangshu Xiao, Bingbing Li
Keywords(s): Therapeutics, Therapeutics - Cancer
Category(s): Chemical, Therapeutics
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