Search Results - therapeutics+-+other

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Malaria transmission blocking using ELQ-infused bed nets

Summary Insecticide-treated mosquito bed nets reduce the transmission of malaria, but mosquitos have developed resistance to insecticides leading to reduced efficacy. Our new technology is a chemical solution for mosquito nets that kills malaria, is less prone to drug-resistance and is not toxic to humans. Technology Overview Insecticide-treated...

Published: 10/15/2024 | Inventor(s): Michael Riscoe, Aaron Nilsen, Joseph (Stone) Doggett, Flaminia Catteruccia, Douglas (Doug) Paton

Keywords(s): Therapeutics, Therapeutics - Infectious Diseases, Therapeutics - Other

Category(s): Therapeutics, Device, Chemical

CD74 as a biomarker and therapeutic target for familial platelet (FPD) disorder

Summary Research at OHSU has identified the CD74 signaling cascade as a potential therapeutic target and diagnostic biomarker for RUNX1-mutated familial platelet disorder (FPD), which is a premalignant condition for acute myeloid leukemia. Technology Overview Current estimates suggest as many as 18,000 people may be living with RUNX1-FPD in the United...

Published: 2/27/2024 | Inventor(s): Anupriya Agarwal, Mona Mohammadhosseini

Keywords(s): Diagnostics, Diagnostics - Cancer, Diagnostics - Other, Therapeutics, Therapeutics - Cancer, Therapeutics - Other

Category(s): Diagnostics, Therapeutics

Compositions for treatment of neurological and oxidative stress disorders

Summary Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health & Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. Technology...

Published: 10/3/2022 | Inventor(s): Michael Cohen, Michael Forte, Justina Sileikyte, Jordan Devereaux, Aaron Nilsen, Paolo Bernardi

Keywords(s): Therapeutics, Therapeutics - Neurology, Therapeutics - Other

Category(s): Therapeutics

Oligonucleotides for long QT syndrome

Summary The current technology consists for compositions under development for the treatment of cardiovascular arrhythmias, specifically Long-QT Syndrome. Technology Overview KCNH2, also known as ether-a-go-go related gene 1 (hERG1) encodes the Kv11.1 channel that conducts the rapidly activating delayed rectifier K+ current in the heart. These channels...

Published: 12/12/2023 | Inventor(s): Zhengfeng Zhou, Qiuming Gong, Matthew Stump

Keywords(s): Therapeutics, Therapeutics - General, Therapeutics - Other

Category(s): Therapeutics