Search Results - aaron+nilsen

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Malaria transmission blocking using ELQ-infused bed nets

Summary Insecticide-treated mosquito bed nets reduce the transmission of malaria, but mosquitos have developed resistance to insecticides leading to reduced efficacy. Our new technology is a chemical solution for mosquito nets that kills malaria, is less prone to drug-resistance and is not toxic to humans. Technology Overview Insecticide-treated...

Published: 10/15/2024 | Inventor(s): Michael Riscoe, Aaron Nilsen, Joseph (Stone) Doggett, Flaminia Catteruccia, Douglas (Doug) Paton

Keywords(s): Therapeutics, Therapeutics - Infectious Diseases, Therapeutics - Other

Category(s): Therapeutics, Device, Chemical

Compositions for treatment of neurological and oxidative stress disorders

Summary Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health & Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. Technology...

Published: 10/3/2022 | Inventor(s): Michael Cohen, Michael Forte, Justina Sileikyte, Jordan Devereaux, Aaron Nilsen, Paolo Bernardi

Keywords(s): Therapeutics, Therapeutics - Neurology, Therapeutics - Other

Category(s): Therapeutics

Cloroquine replacement drugs

Summary Researchers at Oregon Health & Science University and at the Portland VA Medical Center have discovered and optimized a novel class of antimalarial compounds that are superior to the standard of care. Technology Overview Malaria remains one of the deadliest diseases in the world today, as it has been for thousands of years. For each of...

Published: 9/22/2022 | Inventor(s): Michael Riscoe, Rolf Winter, Sovitj Pou, David Hinrichs, Jane Kelly, Yuexin Li, Aaron Nilsen

Keywords(s): Therapeutics, Therapeutics - Infectious Diseases

Category(s): Therapeutics, Chemical