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Compositions for treatment of neurological and oxidative stress disorders
Summary Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health & Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. Technology...
Published: 10/3/2022   |   Inventor(s): Michael Cohen, Michael Forte, Justina Sileikyte, Jordan Devereaux, Aaron Nilsen, Paolo Bernardi
Keywords(s): Therapeutics, Therapeutics - Neurology, Therapeutics - Other
Category(s): Therapeutics
Small molecule inhibitors of the mitochondrial permeability transition pore (PTP)
Summary Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health & Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. Technology...
Published: 9/23/2022   |   Inventor(s): Michael Forte, Dennis Bourdette, Paolo Bernardi, Justina Sileikyte, Frank Schoenen, Sudeshna Roy
Keywords(s): Therapeutics, Therapeutics - Cardiology, Therapeutics - Neurology
Category(s): Therapeutics
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