Search Results - dmitry temiakov

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Methods to limit pathogenic mitochondrial DNA amplification in mitochondrial replacement therapy
Technology Overview Maternally inherited mitochondrial DNA (mtDNA) mutations, estimated to affect 778 newborns in US each year, result in mitochondrial dysfunction and may cause severe and life threatening disease with no effective treatment, such as Leigh Syndrome, MELAS or NARP. Therefore, mitochondrial replacement techniques have been developed to...
Published: 6/22/2017   |   Inventor(s): Dmitry Temiakov, Shoukhrat Mitalipov
Keywords(s): Biological Materials, Biological Materials - Cell Lines, Therapeutics - Reproductive
Category(s): Biological Materials, Therapeutics
A method to increase pregnancy rates for treatment of infertility
Technology OverviewBecause of the trend toward delayed childbearing in the Western world, the age-related infertility, embryonic and fetal loss, as well as birth defects are common. The main cause of this type of infertility, as several findings implicate, is the decline in oocyte quality associated to cytoplasmic deficiencies and mitochondrial dysfunction....
Published: 6/22/2017   |   Inventor(s): Shoukhrat Mitalipov, Nuria Marti-Gutierrez, Dmitry Temiakov
Keywords(s): Biological Materials - Cell Lines, Therapeutics - Reproductive
Category(s): Biological Materials, Therapeutics
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