Search Results - dhanir+tailor

2 Results Sort By:
Anti-cancer Compounds with Improved Cardiac Safety and Drug Resistance Profiles
SummaryTyrosine kinase inhibitors are effective targeted anti-cancer therapeutics, but currently available inhibitors have limitations due to drug resistance and cardiotoxic effects. Oregon Health & Science University researchers have developed a class of kinase inhibitors with an improved cardiovascular safety profile and the potential to overcome...
Published: 9/7/2021   |   Inventor(s): Sanjay Malhotra, Mallesh Pandrala, Dhanir Tailor, Mark Mercola, Arne Antoon Bruyneel
Keywords(s): Therapeutics, Therapeutics - Cancer
Category(s): Therapeutics
A first in class small molecule as a novel YB1 inhibitor.
SummaryThe development of resistance to chemotherapy treatment in solid tumors is associated with up-regulation of the DNA/RNA binding protein Y box binding protein 1 (YB-1) and a worsened prognosis for cancer patients. Oregon Health & Science University researchers have developed a first-in-class small molecule inhibitor of YB-1 that synergizes...
Published: 9/7/2021   |   Inventor(s): Sanjay Malhotra, Dhanir Tailor
Keywords(s): Therapeutics, Therapeutics - Cancer
Category(s): Therapeutics
© 2021. All Rights Reserved. Powered by Inteum