Search Results - t.+zabriskie

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Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin

Background The emerging and persistent threat of multidrug-resistant bacterial infections has resulted in enormous healthcare costs and poses major challenges to public health. To address the need for new antibiotics capable of combating the gowning problem of resistance, Oregon State University researchers cloned and patented the biosynthetic gene...

Published: 9/12/2024 | Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Apoptolidin-producing Strain Amycolatopsis sp. ICBB 8242

Background Apoptolidin is a macrolide. It was originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells. Technology Description A bacterial strain that produces a family of antibiotic compounds known as the apoptolidins. The predominant compound produced is apoptolidin A. Benefits...

Published: 6/17/2024 | Inventor(s): T. Zabriskie, Dwi Andreas Santosa, Taifo Mahmud, Philip Proteau

Keywords(s): Chemicals / Chemical Engineering, pharmaceuticals

Category(s): Research Tools