Search Results - taifo+mahmud

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Pactamycin Analogs Having Antibacterial, Antitumor, and Antimalarial Activity

Background The global emergence of multi-drug resistant bacterial infections has resulted in enormous costs and has become a major threat to public health. About seventy percent of nosocomial infections are resistant to at least one commonly use antibiotic. Pactamycin is a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum....

Published: 6/17/2024 | Inventor(s): Taifo Mahmud, Takuya Ito, Niran Roongsawang, Norifumi Shirasaka, Patricia Flatt

Keywords(s): Antibiotics, antiviral, Cancer, Malaria

Category(s): Therapeutics

Apoptolidin-producing Strain Amycolatopsis sp. ICBB 8242

Background Apoptolidin is a macrolide. It was originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells. Technology Description A bacterial strain that produces a family of antibiotic compounds known as the apoptolidins. The predominant compound produced is apoptolidin A. Benefits...

Published: 6/17/2024 | Inventor(s): T. Zabriskie, Dwi Andreas Santosa, Taifo Mahmud, Philip Proteau

Keywords(s): Chemicals / Chemical Engineering, pharmaceuticals

Category(s): Research Tools