Apoptolidin-producing Strain Amycolatopsis sp. ICBB 8242

Case ID:
OSU-11-43
Web Published:
12/24/2013
Description:

Background
Apoptolidin is a macrolide. It was originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells.

Technology Description
A bacterial strain that produces a family of antibiotic compounds known as the apoptolidins. The predominant compound produced is apoptolidin A.

  • Benefits include Increased Yield compared to published strains
  • Applications include antibiotic and anticancer lead compound development

Opportunity
Seeking a licensee, industry research sponsor, or collaborative research opportunity

Status
Available under a non-exclusive biological material license

Patent Information:
Category(s):
Research Tools
For Information, Contact:
Joe Christison
Assistant Director, IP & Licensing
Oregon State University
541-737-9016
joe.christison@oregonstate.edu
Inventors:
T. Zabriskie
Dwi Andreas Santosa
Taifo Mahmud
Philip Proteau
Keywords:
Chemicals / Chemical Engineering
pharmaceuticals
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