Search Results - medical+science+%26+technologies

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Biosynthetic Gene Cluster for the Peptide Antibiotic Enduracidin

Background The emerging and persistent threat of multidrug-resistant bacterial infections has resulted in enormous healthcare costs and poses major challenges to public health. To address the need for new antibiotics capable of combating the gowning problem of resistance, Oregon State University researchers cloned and patented the biosynthetic gene...

Published: 9/12/2024 | Inventor(s): T. Zabriskie, Xihou 希厚 Yin 银

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Photoreactor for Treatment of Jaundice

Technology Description Oregon State University is seeking a licensee or research collaborator for development or commercialization of a microfluidic visible light photoreactor for the treatment of jaundice in neonatal patients. The device enables safe extracorporeal blood treatment, making it an excellent replacement for equally effective, yet risky,...

Published: 1/16/2023 | Inventor(s): John Lahmann, Adam Higgins

Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Bilirubin, Blood, hyperbilirubinemia, light, Medical Science & Technologies, Neonatal, Newborn, Photoreactor, Sepsis, treatment

Category(s): Medical Devices, Therapeutics, Engineering

A Method to Treat Alzheimer’s, Heart and Liver Diseases

Technology Description This technology describes a process for the preparation of the tripeptide glutathione or its precursors to be delivered to the mitochondria for treating age-related conditions, toxicologic exposures, neurodegeneration, heart disease, and liver damage. More specifically, glutathione precursors and derivatives are coupled to a lipophilic...

Published: 5/26/2021 | Inventor(s): Tory Hagen, Joseph Beckman, Pamela Beilby

Keywords(s): ALS, Alzheimer's, Antioxidant, Cancer, Liver disease, Medical Science & Technologies, Mitochondria, Neurodegenerative disease

Category(s): Biological Materials, Chemical, Diagnostics, Research Tools, Therapeutics

Engineering Mechanisms to Connect One Muscle to Multiple Tendons in Surgery

Technology Description This technology is a new tendon-transfer surgical procedure that uses an implanted passive engineering mechanism for attaching multiple tendons to a single donor muscle. This improves hand function in physical interaction tasks such as grasping over the conventional method of directly suturing multiple tendons to a single muscle.Features...

Published: 7/30/2024 | Inventor(s): Ravi Balasubramanian, Taymaz Homayouni

Keywords(s): Biomedical, Materials Science, Medical Science & Technologies, Veterinary Science & Technologies

Category(s): Medical Devices, Engineering, Device, Therapeutics

Fluidic devices with photo-actuated gates and re-patternable channels

Background Microfluidic devices are a popular means of analyzing minute quantities of samples and feature high-throughput sampling capabilities and suitability for providing highly controlled microreactor environments; however, many types of microfluidic devices and related fabrication approaches can be costly and require great effort and time to...

Published: 6/17/2024 | Inventor(s): Vincent Remcho, Jintana Nammoonnoy, Myra Koesdjojo

Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Biological & Environmental Engineering, Biomedical, Biotechnology, Chemicals / Chemical Engineering, Diagnostic, Medical Science & Technologies, Multiplexing, Nanotechnology, Physics / Applied Engineering, Research Tools

Category(s): Device, Chemical, Chemistry, Diagnostics, Engineering, Nanoscience & Microtechnologies, Research Tools

Antiproliferative Peptide Coibamide A

Background Cancer is one of the leading causes of morbidity and mortality worldwide, and the number of cases is expected to rise to 22 million over the next 2 decades. Modified natural products continue to be an important source for new drugs that address unmet needs in the battle against cancer. Technology Description Researchers at Oregon...

Published: 6/17/2024 | Inventor(s): Kerry Mcphail, Rebecca Medina, William Gerwick, Douglas Goeger, Susan Moobery, Todd Capson

Keywords(s): Biomedical, Biotechnology, Medical Science & Technologies, pharmaceuticals

Category(s): Therapeutics

Natural dairy product biopolymer thickener from Lactococcus lactis Ropy352

Technology Description Natural polysaccharides produced by Ropy352 gives the yogurt a thick, smooth and sweet taste and are generally considered safe. Therefore, no other polysaccharides, like dextran, xanthan, and gellan from potentially pyrogenic inducing bacteria, are needed.Features & Benefits Natural and Generally Regarded As Safe (GRAS)Yogurt...

Published: 11/19/2024 | Inventor(s): Janine Trempy, Eric Knoshaug, William Sandine, Jeff Ahlgren, Karen Dierksen

Keywords(s): Agriculture, Food Science / Nutrition, Medical Science & Technologies, pharmaceuticals

Category(s): Agricultural, Chemistry, Research Tools