Search Results - therapeutics+-+cardiology

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Small molecules promoting nerve regeneration

Summary Nerve regeneration is critical after an injury for proper healing and restoration of function, but many tissues, such as the heart and spinal cord, lack this capacity due to extensive scarring resulting in more permanent injury and loss of function. Researchers at Oregon Health & Science have discovered novel compounds that promote nerve...

Published: 9/21/2023 | Inventor(s): Michael Cohen, Beth Habecker, Haihong Jin, Ryan Gardner, Matthew Blake

Keywords(s): Therapeutics - Cardiology, Therapeutics - Neurology

Category(s): Therapeutics

Small molecule inhibitors of the mitochondrial permeability transition pore (PTP)

Summary Dysfunction of the mitochondrial permeability transition pore (mtPTP) is associated with accumulation of reactive oxygen species (ROS) in many disease states. Researchers at Oregon Health & Science University, University of Kansas, and University of Padova have developed highly potent and stable small molecule inhibitors of mtPTP. Technology...

Published: 9/23/2022 | Inventor(s): Michael Forte, Dennis Bourdette, Paolo Bernardi, Justina Sileikyte, Frank Schoenen, Sudeshna Roy

Keywords(s): Therapeutics, Therapeutics - Cardiology, Therapeutics - Neurology

Category(s): Therapeutics