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Many types of cancer, including carcinomas, lymphomas, sarcomas, and others, are treated with the chemotherapy agent Cisplatin. Based on the element platinum, cisplatin causes apoptosis in cancer cells by cross-linking their DNA. Like many chemotherapy agents, Cisplatin's effectiveness could be improved by better understanding how the body moves it...

Published: 1/18/2019 | Inventor(s): Robert Strongin, Martha Sibrian-Vazquez, Jorge Escobedo, Peter Streyger

Keywords(s): Biology, Chemistry, Drug Screening, Therapeutics

Category(s): Therapeutics

Screen for Redox Activity of Compounds

The design of new and effective drugs is a multi-billion dollar business, requiring great expense and extensive testing of drug candidate compounds. Obtaining a better understanding of the pharmacodynamics and mechanisms of action of drug candidates is an important and necessary step in optimizing any lead compound. A property of increasing...

Published: 1/18/2019 | Inventor(s): Jonathan Abramson, Benjamin Marinov, Rotimi Olojo

Keywords(s): Biology, Chemistry, Drug Screening

Category(s): Therapeutics