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Aptamer-siRNA chimera targeting RORĪ³t in Th17 cells for topical therapy of psoriasis
Summary Researchers at Oregon Health & Science University and at the Portland VA Medical Center have discovered and validated a novel aptamer-siRNA chimera targeting RORγt in Th17 cells for topical treatment of psoriasis. Technology Overview Th17 cells produce several inflammatory cytokines, including IL-17, IL-17F, IL-22 and IL-21 which...
Published: 9/22/2022   |   Inventor(s): Cong-Qiu Chu, Gang Wang
Keywords(s): Therapeutics - Dermatology
Category(s): Therapeutics
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