Search Results - george thomas

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A therapeutic approach to minimize residual disease and relapse in cancer
Technology SummaryOHSU researchers have identified a novel treatment method which, when used in combination with first-line cancer therapies, has the potential to minimize residual disease, the primary cause of relapse in all cancers. The method leverages existing drugs that inhibit a metabolic target molecule not previously understood to be invol...
Published: 1/18/2019   |   Inventor(s): George Thomas, Hui-wen Lue, Jennifer Podolak, Kevin Kolahi
Keywords(s): Therapeutics - Cancer
Category(s): Therapeutics
Use of Von Hippel-Lindau (VHL) as a marker to identify cancer patients responsive to Src kinase inhibitors
Targeted therapies are effective in treating homogeneous cancers driven by a single activating oncogene. However, they are much less effective at treating molecularly heterogeneous cancers, such as metastatic Renal Cell Carcinoma (RCC). Thus, there is an ongoing need to identify cancer biomarkers that can be used to determine appropriate and effe...
Published: 6/22/2016   |   Inventor(s): George Thomas
Keywords(s): Diagnostics
Category(s): Diagnostics
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