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Small molecules promoting nerve regeneration
Summary Nerve regeneration is critical after an injury for proper healing and restoration of function, but many tissues, such as the heart and spinal cord, lack this capacity due to extensive scarring resulting in more permanent injury and loss of function. Researchers at Oregon Health & Science have discovered novel compounds that promote nerve...
Published: 9/21/2023
|
Inventor(s):
Michael Cohen
,
Beth Habecker
,
Haihong Jin
,
Ryan Gardner
,
Matthew Blake
Keywords(s):
Therapeutics - Cardiology
,
Therapeutics - Neurology
Category(s):
Therapeutics
Method for identifying Family-Member Specific Targets of Mono-PARPs
Summary Technology developed at OHSU provides a novel method to identify proteins regulated by PARP mono-ADP-ribosylation (MARylation), a post-translational modification carried out by the majority of enzymes within this family. This tool has the ability to link such PARPs to specific targets and broader biological pathways, thereby increasing our understanding...
Published: 9/29/2022
|
Inventor(s):
Michael Cohen
,
Ian Carter-O'Connell
,
Rory Morgan
,
Haihong Jin
Keywords(s):
Diagnostics - Platforms
,
Research Tools
Category(s):
Diagnostics
,
Proteomics
,
Research Tools
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