Search Results - imaging

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Artificial Intelligence-Assisted Projection-Resolved Optical Coherence Tomographic Angiography (aiPR-OCTA)

Summary The current artificial intelligence algorithm removes projection artifacts in optical coherence tomographic angiography images and improves the signal-to-noise ratio. Technology Overview A major limitation of optical coherence tomography angiography (OCTA) are image artifacts, particularly projection artifacts, which make the detection of...

Published: 2/2/2024 | Inventor(s): Yali Jia, Jie Wang

Keywords(s): Imaging, Imaging - Other

Category(s): Imaging

An OCT method to improve scleral lens fitting

Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...

Published: 1/5/2024 | Inventor(s): David Huang, Yan Li, Clara Llorens Quintana

Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Imaging, Software

Nanoparticle ultrasound contrast agents with high acoustic activity

Summary Contrast-enhanced ultrasound allows for low-cost minimally-invasive imaging; however, the size of typical contrast reagents prevents them from penetrating tumors thereby limiting their utility for cancer diagnostic and therapeutic purposes (theranostics). Oregon Health & Science University (OHSU) researchers have developed novel nanoparticle...

Published: 11/22/2023 | Inventor(s): Adem Yildirim, Jose Luis Montoya Mira, Sadik Esener, Stuart Ibsen

Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Acoustic, Research Tools, Therapeutics

Category(s): Diagnostics, Imaging, Nanoscience & Microtechnologies, Research Tools, Therapeutics

Anoxic/hypoxic brain imaging map

Summary Brain damage in newborns arises as a consequence of oxygen shortage in the brain. This injury is often difficult to diagnose in young children due to intrinsic differences between the developing and adult brain. Scientists at OHSU have developed a highly-accurate diagnostic analysis to localize brain injuries in developing as well as adult brains....

Published: 3/16/2023 | Inventor(s): Jeffrey Pollock, Ningcheng (Peter) Li

Keywords(s): Diagnostics, Diagnostics - Neurology, Imaging, Imaging - MRI

Category(s): Diagnostics, Imaging

Metabolic activity diffusion imaging (MADI): dye-free, high-resolution MRI metabolic imaging

Summary The current technology is a contrast agent-free method of metabolic imaging based on detection of Na/K ATPase activity with MRI, that provides significantly higher resolution than current approaches such as PET. Technology Overview Measuring metabolic activity in vivo can facilitate diagnoses of disease states and therapeutic responses....

Published: 1/15/2024 | Inventor(s): Gregory Wilson, Jeffrey Maki, Charles Springer, Jr., Xin Li, William (Bill) Rooney, Brendan Moloney, Wei Huang, Tom Barbara, Eric Baker

Keywords(s): Diagnostics, Imaging, Imaging - MRI, Software, Software - Other

Category(s): Imaging, Software

Label-free fluorescent sensing of protease activity

Summary The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. Technology Overview Dysregulated proteolytic activity is linked to many human diseases, including...

Published: 7/19/2024 | Inventor(s): Adem Yildirim, Bruce Branchaud, Justin Plaut, Srivathsan Ranganathan, Sean Speese, Corey Dambacher, Sarah Barnhill, Emma Olson

Keywords(s): Diagnostics, Imaging, Imaging - Other, Research Tools

Category(s): Imaging, Research Tools, Diagnostics

Improved removal of projection artifacts in optical coherence tomographic angiography

Summary The current algorithm improves projection artifacts removal for more accurate optical coherence tomographic angiography (OCTA) scans and better quantitative detection and monitoring of vascular abnormalities. Technology Overview Projection artifacts are one of the significant limitations of OCTA imaging, and a reliable projection-resolved...

Published: 9/27/2023 | Inventor(s): Yali Jia, Jie Wang

Keywords(s): Diagnostics, Diagnostics - Other, Imaging, Imaging - Other

Category(s): Imaging, Diagnostics

Software for deep learning-based inference of biomarker distribution in cancer samples

Summary Multiplexed tissue imaging (MTI) is a powerful tool for cancer pathology, but it is also expensive, which has limited its availability for underserved communities, particularly in the developing world. The current software uses hematoxylin & eosin (H&E) staining, which is more widely available, to predict oncology biomarker distribution,...

Published: 9/27/2023 | Inventor(s): Young Hwan Chang, Erik Burlingame, Geoffrey Schau, Elliot Gray

Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Diagnostics, Software

Framework for 3D retinal pathology detection by OCT/OCT-angiography

Summary The current technology provides a platform for a fully-automated OCT-based 3D detection of retinal pathologies with significantly reduced processing requirements, which could allow for more wide-spread adoption of OCT/OCT-angiography 3D analysis. Technology Overview Optical coherence tomography (OCT) and its angiography can be used to provide...

Published: 3/1/2023 | Inventor(s): Yali Jia, Shaohua Pi

Keywords(s): Diagnostics, Imaging, Software, Software - Diagnostic/Detection

Category(s): Diagnostics, Imaging, Software

Fully-automated diabetic retinopathy (DR) screening based on OCT and its angiography

Summary The current technology provides a framework for a fully-automated deep-learning-based diabetic retinopathy screening that relies solely on optical coherence tomography (OCT) and its angiography, without the need for fundus photography or time-intensive clinical evaluation. Technology Overview Diabetic retinopathy (DR) is a leading cause of...

Published: 10/14/2022 | Inventor(s): Yali Jia, Pengxiao Zang

Keywords(s): Diagnostics, Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Diagnostics, Imaging, Software

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