Search Results - bruce+branchaud

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Summary De novo protein-sequencing approaches are poised to revolutionize nearly all fields of biological research and medicine; however current approaches are low-throughput and limited in their sensitivity. The current technology is a novel method that could be implemented with existing reagents and equipment to improve de novo peptide sequencing...

Published: 7/19/2024 | Inventor(s): Eugene Tu, Fehmi Civitci, Kevin Schilling, Mingchong Dai, Nicholas Groves, Justin Plaut, Srivathsan Ranganathan, Andy Mendoza, Riccardo Carloni, Yu-Jui (Roger) Chiu, Emine (Sila) Ozdemir, Bruce Branchaud

Keywords(s): Research Tools, Research Tools - Other

Category(s): Proteomics, Research Tools

Label-free fluorescent sensing of protease activity

Summary The current technology offers advantages over existing protease probes, with lower background noise, simplified label-free synthesis, compatibility with any protease of interest and utility for translational research and clinical diagnostics. Technology Overview Dysregulated proteolytic activity is linked to many human diseases, including...

Published: 7/19/2024 | Inventor(s): Adem Yildirim, Bruce Branchaud, Justin Plaut, Srivathsan Ranganathan, Sean Speese, Corey Dambacher, Sarah Barnhill, Emma Olson

Keywords(s): Diagnostics, Imaging, Imaging - Other, Research Tools

Category(s): Imaging, Research Tools, Diagnostics

Universal nanoprobes for imaging and treatment of cancer

Summary Medical imaging is currently incapable of detecting very small tumors and there is a need for new contrast agents that allow for earlier detection of cancers. The current technology is a self-assembled nanoprobe that specifically accumulates in a broad range of solid tumors to enable 1) high-resolution imaging for earlier cancer detection and...

Published: 9/21/2023 | Inventor(s): Adem Yildirim, Jared Fischer, Bruce Branchaud

Keywords(s): Diagnostics, Diagnostics - Cancer, Imaging, Therapeutics, Therapeutics - Cancer

Category(s): Diagnostics, Imaging, Therapeutics

Nanohoops as new tools in biotechnology

HEADLINE: Groundbreaking fluorescent marker technology using nanohoops Description: Biocompatible fluorescent molecules are essential for observing complex biological events in real time. Our groundbreaking fluorescent marker technology gives researchers a new kind of optical tag to use in biotechnology, biomedical sciences and chemical biology research....

Published: 5/2/2022 | Inventor(s): Ramesh Jasti, Bruce Branchaud, Brittany White

Keywords(s):

Category(s): Chemistry