Search Results - arthur+vandenbark

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Recombinant human CD74 for cancer and immunology research

Summary A recombinant chimeric version of CD74 containing the human extracellular domain, which binds MIF-1 and MIF-2 and has the potential as a valuable research tool for cancer and immunology studies examining the CD74-MIF axis. Technology Overview CD74 interactions with migration inhibitory factor (MIF) is a growing area of cancer and immunology...

Published: 9/19/2023 | Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek

Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools

Category(s): Biological Materials, Research Tools

Compounds that bind macrophage migration inhibitory factor

Summary Recombinant polypeptide composition, which selectively block key pro-inflammatory factors that could stop multiple sclerosis (MS) progression. Technology Overview MIF acts on the immune system to recruit inflammatory factors within injured tissues, including the central nervous system in MS. Upon binding to its receptor, CD74, MIF activates...

Published: 9/21/2023 | Inventor(s): Arthur Vandenbark, Gil Benedek, Roberto Meza-Romero

Keywords(s): Therapeutics, Therapeutics - Immunology

Category(s): Therapeutics

Mouse CD74: Design, codon optimization, cloning, expression in E coli, and purification

Summary Recombinant mouse CD74 for use as a research reagent to explore CD74 protein interactions. Technology Overview This recombinant mouse CD74 is a 191 amino acid residue polypeptide that lacks the C-terminal thyroglobulin domain. It is an E. coli expressed mouse protein that includes the intracellular domain (N-terminal amino acid residues...

Published: 9/29/2022 | Inventor(s): Roberto Meza-Romero, Arthur Vandenbark, Gil Benedek

Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Research Tools

Category(s): Biological Materials, Research Tools