Search Results - summer+dowell+(gibbs)

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SummaryMulticolor microscopy can be used to localize and visualize complex subcellular systems, but current systems are often limited in the number of fluorophores that can be imaged simultaneously. Oregon Health & Science University researchers have developed novel fluorophores that increase the number of channels and subcellular structures that...

Published: 12/2/2021 | Inventor(s): Summer Dowell (Gibbs), Amy Bittel, Xiaolin Nan

Keywords(s): Imaging, Research Tools, Research Tools - Reagents

Category(s): Imaging, Research Tools

Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications

Summary Rhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...

Published: 9/21/2023 | Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano

Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents

Category(s): Imaging, Research Tools

Fluorescence microscope for high resolution imaging and single-molecule tracking

Summary Super-resolution microscopy and single-molecule tracking are powerful tools for biological research, but multicolor experiments have been difficult due to spectral crosstalk between fluorophores. Scientists at OHSU have developed a simple-to-use multispectral super-resolution microscope (MSSRM) system, compatible with live- or fixed-cell imaging...

Published: 9/30/2022 | Inventor(s): Don Kania, Joe Gray, Steven Jacques, Summer Dowell (Gibbs), Xiaolin Nan

Keywords(s): Device, Engineering & Physical Science, Imaging, Research Tools

Category(s): Device, Engineering, Imaging, Physical Science, Research Tools

Adipose-specific fluorescent dyes for in vivo imaging

Summary Researchers at Oregon Health & Science University have developed novel adipose-specific fluorescent dyes for use in image-guided surgery of anatomical structures, such as nerves, that are surrounded by adipose tissue. The generated fluorophores exhibit reduced nerve accumulation, and demonstrate higher adipose-to-nerve and adipose-to-muscle...

Published: 10/3/2023 | Inventor(s): Jesse Korber, Connor Barth, Summer Dowell (Gibbs)

Keywords(s): Diagnostics, Imaging

Category(s): Diagnostics, Imaging