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Biological H2S / COS Donation by Thiocarbamates
University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...
Published: 5/2/2022
|
Inventor(s):
Michael Pluth
,
Andrea Steiger
,
Yu Zhao
Keywords(s):
Category(s):
Chemistry
,
Physical Science
,
Therapeutics
A new method for detection for hydrosulfide anion (HS-) and hydrogen sulfide (H2S)
Hydrogen sulfide (H2S), although generally known for its toxicity and characteristic odor, is now recognized as an important signaling molecule with diverse biological roles. The biological roles of H2S range from roles in angiogenesis to wound healing. In mammals, H2S production is derived primarily from three enzymes: cystathionine-γ-lyase...
Published: 11/4/2024
|
Inventor(s):
Michael Haley
,
Darren Johnson
,
Michael Pluth
,
Ryan Hansen
,
Matt Hartle
,
Blakely Tresca
Keywords(s):
Category(s):
Chemistry
,
Materials Science
,
Nanoscience & Microtechnologies
,
Physical Science
,
Imaging
Compounds for Thiol-Triggered COS and/or H2s Release and Methods of Making and Using the Same
University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in a class...
Published: 5/2/2022
|
Inventor(s):
Michael Pluth
,
Yu Zhao
,
Matt Cerda
Keywords(s):
Science
Category(s):
Chemistry
,
Engineering
,
Medical Devices
,
Physical Science
,
Therapeutics
Thionoesters that Release H2S upon Thiol Ligation
University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in a class...
Published: 5/2/2022
|
Inventor(s):
Michael Pluth
,
Matt Cerda
Keywords(s):
Science
Category(s):
Chemistry
,
Diagnostics
,
Medical Devices
,
Physical Science
,
Therapeutics
Gamma-ketothiocarbamate molecules that release COS
University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...
Published: 5/2/2022
|
Inventor(s):
Michael Pluth
,
Yu Zhao
Keywords(s):
Category(s):
Chemistry
,
Diagnostics
,
Engineering
,
Medical Devices
,
Physical Science
,
Research Tools
,
Therapeutics
Chemiluminescent Probe for H2S Detection
Hydrogen sulfide is an important biological signalling molecule and an important environmental detection target. Biological H2S exhibits significant effects in both the cardiovascular and neuronal systems and is produced endogenously from cystathionine-β-synthase (CBS), cystathionine-gamma-lyase (CSE), and 3-mercaptopyruvate sulfur transferase...
Published: 10/1/2021
|
Inventor(s):
Michael Pluth
,
Thomas "spencer" Bailey
Keywords(s):
Category(s):
Chemistry
Colorimetric H2S Detection
Hydrogen sulfide is an important biological signalling molecule and an important environmental detection target. Biological H2S exhibits significant effects in both the cardiovascular and neuronal systems and is produced endogenously from cystathionine-β-synthase (CBS), cystathionine-gamma-lyase (CSE), and 3-mercaptopyruvate sulfur transferase...
Published: 10/1/2021
|
Inventor(s):
Michael Pluth
,
Taylor Pearce
,
Leticia Montoya
Keywords(s):
Category(s):
Chemistry
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