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Radiation-enhanced delivery of antisense oligonucleotides against MGMT

Summary MGMT is a critical enzyme driving DNA repair, and down-regulation of this molecule in tumors is linked to increased efficacy of cancer therapies that promote DNA damage and apoptosis of cancer cells. Researchers at the Veteran’s Affair Hospital and Oregon Health & Science University have developed a new cancer therapeutic strategy...

Published: 9/30/2022 | Inventor(s): Prakash Ambady, Ying-Jen (Jeffrey) Wu, Edward Neuwelt

Keywords(s): Therapeutics - Cancer

Category(s): Therapeutics