Search Results - luiz+bertassoni

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A photocrosslinkable bone derived biomaterial for tissue engineering applications

Summary Demineralized bone matrix has been widely used in the clinic to heal bone injuries due to its remarkable regenerative properties. However, this is not a material that can be synthesized in large batches, with highly reproducible chemistry, and cannot be set/polymerized in-situ for precise adaptation. BoneMA is photopolymerizable material that...

Published: 7/23/2025 | Inventor(s): Luiz Bertassoni, Avathamsa Athirasala

Keywords(s):

Category(s): Therapeutics, Device

eDentin- a tissue engineered reparative dentin

Summary Current dental restoration materials trigger immune responses and poorly replicate the natural structure of the tooth, which delays the healing process. The current technology is a novel biomaterial that more closely mimics natural dentin and thereby allows for more efficient healing of the tooth. Technology Overview Cement-based materials...

Published: 12/3/2024 | Inventor(s): Luiz Bertassoni, Cristiane Miranda Franca

Keywords(s): Dental, Device, Device - Other

Category(s): Dental, Device

A method to regenerate vascularized dental pulp for root canal dental therapy

Summary Current root canal therapies rely on removing necrotic tissue and filling the area with inert material, reducing vascularity in the dental pulp and overall health in the remaining tooth. The laboratory of Dr. Luiz Bertassoni has developed a novel root canal treatment that features a hydrogel filling with a hollow central chamber, which can...

Published: 1/15/2024 | Inventor(s): Luiz Bertassoni, Anthony Tahayeri, Avathamsa Athirasala, Jack Ferracane

Keywords(s):

Category(s): Dental

"Tooth on a chip"- A microfluidic device to test interactions of biomaterials with dental structures

Summary The development of novel dental biomaterials requires in vitro validation and cytotoxicity studies; however, research platforms that accurately emulate the oral environment, the interface between biomaterials with the tooth, and the underlying dental pulp, do not currently exist. This is traditionally done by exposing plated cells to eluents...

Published: 6/21/2024 | Inventor(s): Luiz Bertassoni

Keywords(s): Dental, Device, Research Tools - Other

Category(s): Device