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Morpholino Oligomers to Prevent and Treat Coronavirus Infection

This technology licensing opportunity relates to antisense agents for treating or preventing a SARS-CoV-2 infection. The antisense agents are peptide-conjugated morpholino oligomers targeting pre-mRNA of a host (human) gene that encodes a protease. Some antisense agents included within the scope of this technology include agents previously shown to...

Published: 5/26/2021 | Inventor(s): Hong Moulton, David Stein, Eva Bottcher-Friebershauser

Keywords(s):

Category(s): Therapeutics

Antisense Agents for Treating SARS-CoV-2 Infection

Background In December 2019, cases of an acute respiratory disease were reported from Wuhan, the capital of Hubei province in China. The number of infections increased rapidly and spread to other areas of China and on January 13th, 2020, the first case was reported outside of China. The causative agent was identified as a novel coronavirus (CoV)...

Published: 7/31/2023 | Inventor(s): David Stein, Hong Moulton, Kyle Rosenke, Heinrich Feldmann

Keywords(s): antisense, coronavirus, covid-19, Drug, SARS-CoV-2, Therapeutic

Category(s): Therapeutics